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Volumn 21, Issue 6, 2013, Pages 454-461

Neuroprotective effects of a Butanol fraction of Rosa hybrida petals in a middle cerebral artery occlusion model

Author keywords

Anti inflammation; Antioxidation; Glial fibrillary acidic protein; Ischemic brain injury; Middle cerebral artery occlusion; Rosa hybrida

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; BUTANOL; CYCLOOXYGENASE 2; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROPROTECTIVE AGENT; NITRIC OXIDE SYNTHASE; PLANT EXTRACT; ROSA HYBRIDA EXTRACT; UNCLASSIFIED DRUG;

EID: 84888777128     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2013.067     Document Type: Article
Times cited : (15)

References (34)
  • 2
    • 0032049505 scopus 로고    scopus 로고
    • A reliable procedure for comparison of antioxidants in rat brain homogenates
    • Callaway, J. K., Beart, P. M. and Jarrott, B. (1998) A reliable procedure for comparison of antioxidants in rat brain homogenates. J. Pharmacol. Toxicol. Methods 39, 155-162.
    • (1998) J. Pharmacol. Toxicol. Methods , vol.39 , pp. 155-162
    • Callaway, J.K.1    Beart, P.M.2    Jarrott, B.3
  • 3
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan, P. H. (1996) Role of oxidants in ischemic brain damage. Stroke 27, 1124-1129.
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.H.1
  • 4
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan, P. H. (2001) Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21, 2-14.
    • (2001) J. Cereb. Blood Flow Metab , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 5
    • 0041336987 scopus 로고    scopus 로고
    • Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picryl-hydrazyl radical
    • Cho, E. J., Yokozawa, T., Rhyu, D. Y., Kim, S. L., Shibahara, N. and Park, J. C. (2003) Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picryl-hydrazyl radical. Phytomedicine 10, 544-551.
    • (2003) Phytomedicine , vol.10 , pp. 544-551
    • Cho, E.J.1    Yokozawa, T.2    Rhyu, D.Y.3    Kim, S.L.4    Shibahara, N.5    Park, J.C.6
  • 6
    • 84455167486 scopus 로고    scopus 로고
    • Neurobehavioral deficits correlate with the cerebral infarction volume of stroke animals: A comparative study on isch-emia-reperfusion and photothrombosis models
    • Choi, B. I., Park, D., Lee, S. H., Bae, D. K., Yang, G., Yang, Y. H., Kim, T. K., Choi, E. K., Lee, H. J., Choi, K. C., Nahm, S. S. and Kim, Y. B. (2012) Neurobehavioral deficits correlate with the cerebral infarction volume of stroke animals: a comparative study on isch-emia-reperfusion and photothrombosis models. Environ. Toxicol. Pharmacol. 33, 60-69.
    • (2012) Environ. Toxicol. Pharmacol , vol.33 , pp. 60-69
    • Choi, B.I.1    Park, D.2    Lee, S.H.3    Bae, D.K.4    Yang, G.5    Yang, Y.H.6    Kim, T.K.7    Choi, E.K.8    Lee, H.J.9    Choi, K.C.10    Nahm, S.S.11    Kim, Y.B.12
  • 7
    • 0035075997 scopus 로고    scopus 로고
    • Efficacy of antioxidant therapies in transient focal ischemia in mice
    • Clark, W. M., Rinker, L. G., Lessov, N. S., Lowery, S. L. and Cipolla, M. J. (2001) Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke 32, 1000-1004.
    • (2001) Stroke , vol.32 , pp. 1000-1004
    • Clark, W.M.1    Rinker, L.G.2    Lessov, N.S.3    Lowery, S.L.4    Cipolla, M.J.5
  • 9
    • 0035143182 scopus 로고    scopus 로고
    • Cerebral ischemia and inflammation
    • Iadecola, C. and Alexander, M. (2001) Cerebral ischemia and inflammation. Curr. Opin. Neurol. 14, 89-94.
    • (2001) Curr. Opin. Neurol , vol.14 , pp. 89-94
    • Iadecola, C.1    Alexander, M.2
  • 10
    • 0030664096 scopus 로고    scopus 로고
    • Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
    • Iadecola, C., Zhang, F., Casey, R., Nagayama, M. and Ross, M. E. (1997) Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci. 17, 9157-9164.
    • (1997) J. Neurosci , vol.17 , pp. 9157-9164
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Nagayama, M.4    Ross, M.E.5
  • 12
    • 79961226112 scopus 로고    scopus 로고
    • Antimicrobial and antioxi-dant properties of secondary metabolites from white rose flower
    • Joo, S. S., Kim, Y. B. and Lee, D. I. (2010) Antimicrobial and antioxi-dant properties of secondary metabolites from white rose flower. Plant Pathol. J. 26, 57-62.
    • (2010) Plant Pathol. J , vol.26 , pp. 57-62
    • Joo, S.S.1    Kim, Y.B.2    Lee, D.I.3
  • 13
    • 0032877148 scopus 로고    scopus 로고
    • Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epi-catechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action
    • Kondo, K., Kurihara, M., Miyata, N., Suzuki, T. and Toyoda, M. (1999) Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epi-catechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action. Free Radic. Biol. Med. 27, 855-863.
    • (1999) Free Radic. Biol. Med , vol.27 , pp. 855-863
    • Kondo, K.1    Kurihara, M.2    Miyata, N.3    Suzuki, T.4    Toyoda, M.5
  • 14
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • Lakhan, S. E., Kirchgessner, A. and Hofer, M. (2009) Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J. Transl. Med. 7, 97.
    • (2009) J. Transl. Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hofer, M.3
  • 15
    • 79961228921 scopus 로고    scopus 로고
    • Anti-inflammatory effects of hexane fraction from white rose flower extracts via inhibition of inflammatory repertoires
    • Lee, H. J., Kim, H. S., Kim, S. T., Park, D., Hong, J. T., Kim, Y. B. and Joo, S. S. (2011) Anti-inflammatory effects of hexane fraction from white rose flower extracts via inhibition of inflammatory repertoires. Biomol. Ther. 19, 331-335.
    • (2011) Biomol. Ther , vol.19 , pp. 331-335
    • Lee, H.J.1    Kim, H.S.2    Kim, S.T.3    Park, D.4    Hong, J.T.5    Kim, Y.B.6    Joo, S.S.7
  • 16
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa, E. Z., Weinstein, P. R., Carlson, S. and Cummins, R. (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20, 84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 17
    • 22544462551 scopus 로고    scopus 로고
    • Antioxidant strategies in the treatment of stroke
    • Margaill, I., Plotkine, M. and Lerouet, D. (2005) Antioxidant strategies in the treatment of stroke. Free Radic. Biol. Med. 39, 429-443.
    • (2005) Free Radic. Biol. Med , vol.39 , pp. 429-443
    • Margaill, I.1    Plotkine, M.2    Lerouet, D.3
  • 18
    • 84857458147 scopus 로고    scopus 로고
    • Contribution of nitric oxide synthase (NOS) in blood-brain barrier disruption during acute focal cerebral ischemia in normal rat
    • Mohammadi, M. T., Shid-Moosavi, S. M. and Dehghani, G. A. (2012) Contribution of nitric oxide synthase (NOS) in blood-brain barrier disruption during acute focal cerebral ischemia in normal rat. Pathophysiology 19, 13-20.
    • (2012) Pathophysiology , vol.19 , pp. 13-20
    • Mohammadi, M.T.1    Shid-Moosavi, S.M.2    Dehghani, G.A.3
  • 19
    • 34249660052 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of mono-cyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes
    • Mojsilovic-Petrovic, J., Callaghan, D., Cui, H., Dean, C., Stanimirovic, D. B. and Zhang, W. (2007) Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of mono-cyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes. J. Neuroinflammation 4, 12.
    • (2007) J. Neuroinflammation , vol.4 , pp. 12
    • Mojsilovic-Petrovic, J.1    Callaghan, D.2    Cui, H.3    Dean, C.4    Stanimirovic, D.B.5    Zhang, W.6
  • 20
    • 18344389580 scopus 로고    scopus 로고
    • Rose (Rosa rugosa)-flower extract increases the activities of antioxidant enzymes and their gene expression and reduces lipid peroxidation
    • Ng, T. B., Gao, W., Li, L., Niu, S. M., Zhao, L., Liu, J., Shi, L. S., Fu, M. and Liu, F. (2005) Rose (Rosa rugosa)-flower extract increases the activities of antioxidant enzymes and their gene expression and reduces lipid peroxidation. Biochem. Cell Biol. 83, 78-85.
    • (2005) Biochem. Cell Biol , vol.83 , pp. 78-85
    • Ng, T.B.1    Gao, W.2    Li, L.3    Niu, S.M.4    Zhao, L.5    Liu, J.6    Shi, L.S.7    Fu, M.8    Liu, F.9
  • 22
    • 0032167857 scopus 로고    scopus 로고
    • Interaction between inducible nitric oxide syn-thase and cyclooxygenase-2 after cerebral ischemia
    • Nogawa, S., Forster, C., Zhang, F., Nagayama, M., Ross, M. E. and Iadecola, C. (1998) Interaction between inducible nitric oxide syn-thase and cyclooxygenase-2 after cerebral ischemia. Proc. Natl. Acad. Sci. U.S.A. 95, 10966-10971.
    • (1998) Proc. Natl. Acad. Sci. U.S.A , vol.95 , pp. 10966-10971
    • Nogawa, S.1    Forster, C.2    Zhang, F.3    Nagayama, M.4    Ross, M.E.5    Iadecola, C.6
  • 23
    • 0030909616 scopus 로고    scopus 로고
    • Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage
    • Nogawa, S., Zhang, F., Ross, M. E. and Iadecola, C. (1997) Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage. J. Neurosci. 17, 2746-2755.
    • (1997) J. Neurosci , vol.17 , pp. 2746-2755
    • Nogawa, S.1    Zhang, F.2    Ross, M.E.3    Iadecola, C.4
  • 24
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa, H., Ohishi, N. and Yagi, K. (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95, 351-358.
    • (1979) Anal. Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 26
    • 74549219051 scopus 로고    scopus 로고
    • Antioxidative activities of white rose flower extract and pharmaceutical advantages of its hexane fraction via free radical scavenging effects
    • Park, D., Jeon, J. H., Kwon, S. C., Shin, S., Jang, J. Y., Jeong, H. S., Lee, D. I., Kim, Y. B. and Joo, S. S. (2009) Antioxidative activities of white rose flower extract and pharmaceutical advantages of its hexane fraction via free radical scavenging effects. Biochem. Cell Biol. 87, 943-952.
    • (2009) Biochem. Cell Biol , vol.87 , pp. 943-952
    • Park, D.1    Jeon, J.H.2    Kwon, S.C.3    Shin, S.4    Jang, J.Y.5    Jeong, H.S.6    Lee, D.I.7    Kim, Y.B.8    Joo, S.S.9
  • 27
    • 83155182379 scopus 로고    scopus 로고
    • Microtubule-associated protein 2, an early blood marker of ischemic brain injury
    • Park, D., Joo, S. S., Lee, H., Choi, K. C., Kim, S. U. and Kim, Y. B. (2012) Microtubule-associated protein 2, an early blood marker of ischemic brain injury. J. Neurosci. Res. 90, 461-467.
    • (2012) J. Neurosci. Res , vol.90 , pp. 461-467
    • Park, D.1    Joo, S.S.2    Lee, H.3    Choi, K.C.4    Kim, S.U.5    Kim, Y.B.6
  • 29
    • 84155181890 scopus 로고    scopus 로고
    • Emerging role of astrocytes in cerebral ischemia/ reperfusion injury
    • Raghubir, R. (2008) Emerging role of astrocytes in cerebral ischemia/ reperfusion injury. Ann. Neurosci. 15, 17-24.
    • (2008) Ann. Neurosci , vol.15 , pp. 17-24
    • Raghubir, R.1
  • 30
    • 0030891121 scopus 로고    scopus 로고
    • Photothrombotic lesions of the rat cortex impair acquisition of the water maze
    • Rogers, D. C. and Hunter, A. J. (1997) Photothrombotic lesions of the rat cortex impair acquisition of the water maze. Pharmacol. Bio-chem. Behav. 56, 747-754.
    • (1997) Pharmacol. Bio-chem. Behav , vol.56 , pp. 747-754
    • Rogers, D.C.1    Hunter, A.J.2
  • 31
    • 0031665617 scopus 로고    scopus 로고
    • A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: Evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flow metry
    • Schmid-Elsaesser, R., Zausinger, S., Hungerhuber, E., Baethmann, A. and Reulen, H. J. (1998) A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats by laser-Doppler flow metry. Stroke 29, 2162-2170.
    • (1998) Stroke , vol.29 , pp. 2162-2170
    • Schmid-Elsaesser, R.1    Zausinger, S.2    Hungerhuber, E.3    Baethmann, A.4    Reulen, H.J.5
  • 32
    • 72149093510 scopus 로고    scopus 로고
    • Mitochondria, oxidative metabolism and cell death in stroke
    • Sims, N. R. and Muyderman, H. (2010) Mitochondria, oxidative metabolism and cell death in stroke. Biochim. Biophys. Acta 1802, 80-91.
    • (2010) Biochim. Biophys. Acta , vol.1802 , pp. 80-91
    • Sims, N.R.1    Muyderman, H.2
  • 33
    • 85027946695 scopus 로고    scopus 로고
    • Neuroprotective effect of Spiruli-na in cerebral ischemia-reperfusion injury in rats
    • Thaakur, S. and Sravanthi, R. (2010) Neuroprotective effect of Spiruli-na in cerebral ischemia-reperfusion injury in rats. J. Neural Transm. 117, 1083-1091.
    • (2010) J. Neural Transm , vol.117 , pp. 1083-1091
    • Thaakur, S.1    Sravanthi, R.2
  • 34
    • 0032826065 scopus 로고    scopus 로고
    • Neuroprotective properties of statins in cerebral ischemia and stroke
    • Vaughan, C. J. and Delanty, N. (1999) Neuroprotective properties of statins in cerebral ischemia and stroke. Stroke 30, 1969-1973.
    • (1999) Stroke , vol.30 , pp. 1969-1973
    • Vaughan, C.J.1    Delanty, N.2


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