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Volumn 20, Issue 9, 2009, Pages 715-725

Protective effect of docosahexaenoic acid against brain injury in ischemic rats

Author keywords

Apoptosis; Cerebral ischemia reperfusion; DHA; Inflammation; Neuroprotection; Oxidative stress

Indexed keywords

CASPASE 3; DOCOSAHEXAENOIC ACID; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; SUPEROXIDE DISMUTASE;

EID: 68249126664     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.06.014     Document Type: Article
Times cited : (103)

References (53)
  • 1
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J Neurobiol 23 (1992) 1261-1276
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 2
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia; mechanisms of damage and treatment
    • Siesjö B.K. Pathophysiology and treatment of focal cerebral ischemia; mechanisms of damage and treatment. J Neurosurg 77 (1992) 337-354
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjö, B.K.1
  • 3
    • 0027501851 scopus 로고
    • Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
    • Linnik M.D., Zobrist R.H., and Hatfield M.D. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24 (1993) 2002-2008
    • (1993) Stroke , vol.24 , pp. 2002-2008
    • Linnik, M.D.1    Zobrist, R.H.2    Hatfield, M.D.3
  • 4
    • 0029959730 scopus 로고    scopus 로고
    • Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion
    • Hamann G.F., Okada Y., and del Zoppo G.J. Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion. J Cereb Blood Flow Metab 16 (1996) 1373-1378
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 1373-1378
    • Hamann, G.F.1    Okada, Y.2    del Zoppo, G.J.3
  • 5
    • 0034705731 scopus 로고    scopus 로고
    • Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion
    • Chen C.J., Cheng F.C., Liao S.L., Chen W.Y., Lin N.N., and Kuo J.S. Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion. Neurosci Lett 287 (2000) 113-116
    • (2000) Neurosci Lett , vol.287 , pp. 113-116
    • Chen, C.J.1    Cheng, F.C.2    Liao, S.L.3    Chen, W.Y.4    Lin, N.N.5    Kuo, J.S.6
  • 6
    • 0033795665 scopus 로고    scopus 로고
    • Proinflammatory cytokines and early neurological worsening in ischemic stroke
    • Vila N., Castillo J., Dávalos A., and Chamorro A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke 31 (2000) 2325-2329
    • (2000) Stroke , vol.31 , pp. 2325-2329
    • Vila, N.1    Castillo, J.2    Dávalos, A.3    Chamorro, A.4
  • 7
    • 0035800215 scopus 로고    scopus 로고
    • Association of immune responses and ischemic brain infarction in rat
    • Liao S.L., Chen W.Y., Raung S.L., Kuo J.S., and Chen C.J. Association of immune responses and ischemic brain infarction in rat. NeuroReport 12 (2001) 1943-1947
    • (2001) NeuroReport , vol.12 , pp. 1943-1947
    • Liao, S.L.1    Chen, W.Y.2    Raung, S.L.3    Kuo, J.S.4    Chen, C.J.5
  • 8
    • 0142102436 scopus 로고    scopus 로고
    • Temporal assessment of caspase activation in experimental models of focal and global ischemia
    • Cho S., Liu D., Gonzales C., Zaleska M.M., and Wood A. Temporal assessment of caspase activation in experimental models of focal and global ischemia. Brain Res 982 (2003) 146-155
    • (2003) Brain Res , vol.982 , pp. 146-155
    • Cho, S.1    Liu, D.2    Gonzales, C.3    Zaleska, M.M.4    Wood, A.5
  • 9
    • 2542551340 scopus 로고    scopus 로고
    • Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia
    • Gursoy-Ozdemir Y., Can A., and Dalkara T. Reperfusion-induced oxidative/nitrative injury to neurovascular unit after focal cerebral ischemia. Stroke 35 (2004) 1449-1453
    • (2004) Stroke , vol.35 , pp. 1449-1453
    • Gursoy-Ozdemir, Y.1    Can, A.2    Dalkara, T.3
  • 10
    • 33947628060 scopus 로고    scopus 로고
    • Molecular targets in cerebral ischemia for developing novel therapeutics
    • Mehta S.L., Manhas N., and Raghubir R. Molecular targets in cerebral ischemia for developing novel therapeutics. Brain Res Rev 54 (2007) 34-66
    • (2007) Brain Res Rev , vol.54 , pp. 34-66
    • Mehta, S.L.1    Manhas, N.2    Raghubir, R.3
  • 11
    • 0028801677 scopus 로고
    • High dose methylprednisolone therapy reduces expression of JE/MCP-1 mRNA and macrophage accumulation in the ischemic rat brain
    • Kim J.S., Chopp M., and Gautam S.C. High dose methylprednisolone therapy reduces expression of JE/MCP-1 mRNA and macrophage accumulation in the ischemic rat brain. J Neurol Sci 128 (1995) 28-35
    • (1995) J Neurol Sci , vol.128 , pp. 28-35
    • Kim, J.S.1    Chopp, M.2    Gautam, S.C.3
  • 12
    • 0030698685 scopus 로고    scopus 로고
    • Antileukocyte adhesion therapy: preclinical trials and combination therapy
    • Clark W.M., and Zivin J.A. Antileukocyte adhesion therapy: preclinical trials and combination therapy. Neurology 49 (1997) S32-S38
    • (1997) Neurology , vol.49
    • Clark, W.M.1    Zivin, J.A.2
  • 13
    • 0033011472 scopus 로고    scopus 로고
    • Inhibition of neutrophil migration by a protein kinase inhibitor for the treatment of ischemic brain infarction
    • Satoh S., Kobayashi T., Hitomi A., Ikegaki I., Suzuki Y., Shibuya M., et al. Inhibition of neutrophil migration by a protein kinase inhibitor for the treatment of ischemic brain infarction. Jpn J Pharmacol 80 (1999) 41-48
    • (1999) Jpn J Pharmacol , vol.80 , pp. 41-48
    • Satoh, S.1    Kobayashi, T.2    Hitomi, A.3    Ikegaki, I.4    Suzuki, Y.5    Shibuya, M.6
  • 14
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
    • Yrjanheikki J., Tikka T., Keinanen R., Goldsteins G., Chan P.H., and Koistinaho J. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci USA 96 (1999) 13496-13500
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5    Koistinaho, J.6
  • 15
    • 0033918122 scopus 로고    scopus 로고
    • Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia
    • Phillips J.B., Williams A.J., Adams J., Elliott P.J., and Tortella F.C. Proteasome inhibitor PS519 reduces infarction and attenuates leukocyte infiltration in a rat model of focal cerebral ischemia. Stroke 31 (2000) 1686-1693
    • (2000) Stroke , vol.31 , pp. 1686-1693
    • Phillips, J.B.1    Williams, A.J.2    Adams, J.3    Elliott, P.J.4    Tortella, F.C.5
  • 16
    • 33846194681 scopus 로고    scopus 로고
    • Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat
    • Nagel S., Genius J., Heiland S., Horstmann S., Gardner H., and Wagner S. Diphenyleneiodonium and dimethylsulfoxide for treatment of reperfusion injury in cerebral ischemia of the rat. Brain Res 1132 (2007) 210-217
    • (2007) Brain Res , vol.1132 , pp. 210-217
    • Nagel, S.1    Genius, J.2    Heiland, S.3    Horstmann, S.4    Gardner, H.5    Wagner, S.6
  • 17
    • 3342978256 scopus 로고    scopus 로고
    • Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: effect of dietary fish oil
    • Choi-Kwon S., Park K.A., Lee H.J., Park M.S., Lee J.H., Jeon S.E., et al. Temporal changes in cerebral antioxidant enzyme activities after ischemia and reperfusion in a rat focal brain ischemia model: effect of dietary fish oil. Dev Brain Res 152 (2004) 11-18
    • (2004) Dev Brain Res , vol.152 , pp. 11-18
    • Choi-Kwon, S.1    Park, K.A.2    Lee, H.J.3    Park, M.S.4    Lee, J.H.5    Jeon, S.E.6
  • 18
    • 20244366112 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia
    • Wei L., Cui L., Snider B.J., Rivkin M., Yu S.S., Lee C.S., et al. Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiol Dis 19 (2005) 183-193
    • (2005) Neurobiol Dis , vol.19 , pp. 183-193
    • Wei, L.1    Cui, L.2    Snider, B.J.3    Rivkin, M.4    Yu, S.S.5    Lee, C.S.6
  • 19
    • 10944242029 scopus 로고    scopus 로고
    • Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus
    • Wong L.F., Ralph G.S., Walmsley L.E., Bienemann A.S., Parham S., Kingsman S.M., et al. Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus. Mol Ther 11 (2005) 89-95
    • (2005) Mol Ther , vol.11 , pp. 89-95
    • Wong, L.F.1    Ralph, G.S.2    Walmsley, L.E.3    Bienemann, A.S.4    Parham, S.5    Kingsman, S.M.6
  • 20
    • 33750443222 scopus 로고    scopus 로고
    • Ischemic preconditioning-induced activation of ERK1/2 in the rat hippocampus
    • Choi J.S., Kim H.Y., Cha J.H., and Lee M.Y. Ischemic preconditioning-induced activation of ERK1/2 in the rat hippocampus. Neurosci Lett 409 (2006) 187-191
    • (2006) Neurosci Lett , vol.409 , pp. 187-191
    • Choi, J.S.1    Kim, H.Y.2    Cha, J.H.3    Lee, M.Y.4
  • 21
    • 0030798959 scopus 로고    scopus 로고
    • Fatty acid dietary intake and the risk of ischemic stroke: a multicentre case-control study
    • Ricci S., Celani M.G., Righetti E., Caruso A., Medio G.D., Trovarelli G., et al. Fatty acid dietary intake and the risk of ischemic stroke: a multicentre case-control study. J Neurol 244 (1997) 360-364
    • (1997) J Neurol , vol.244 , pp. 360-364
    • Ricci, S.1    Celani, M.G.2    Righetti, E.3    Caruso, A.4    Medio, G.D.5    Trovarelli, G.6
  • 22
    • 0036330004 scopus 로고    scopus 로고
    • Linoleic acid, other fatty acids, and the risk of stroke
    • Iso H., Sato S., Umemura U., Kudo M., Koike K., Kitamura A., et al. Linoleic acid, other fatty acids, and the risk of stroke. Stroke 33 (2002) 2086-2093
    • (2002) Stroke , vol.33 , pp. 2086-2093
    • Iso, H.1    Sato, S.2    Umemura, U.3    Kudo, M.4    Koike, K.5    Kitamura, A.6
  • 24
  • 25
    • 0042880827 scopus 로고    scopus 로고
    • Measurement of free fatty acids in cerebrospinal fluid from patients with hemorrhagic and ischemic stroke
    • Politsis J.G., Coplin W.M., O'Regan M.H., Wellwood J.M., Diaz F.G., Fairfax M.R., et al. Measurement of free fatty acids in cerebrospinal fluid from patients with hemorrhagic and ischemic stroke. Brain Res 985 (2003) 198-201
    • (2003) Brain Res , vol.985 , pp. 198-201
    • Politsis, J.G.1    Coplin, W.M.2    O'Regan, M.H.3    Wellwood, J.M.4    Diaz, F.G.5    Fairfax, M.R.6
  • 26
    • 34247126893 scopus 로고    scopus 로고
    • Chronic daily administration of ethyl docosahexaenoate protects against gerbil brain ischemic damage through reduction of arachidonic acid liberation and accumulation
    • Cao D., Yang B., Hou L., Xu J., Xue R., Sun L., et al. Chronic daily administration of ethyl docosahexaenoate protects against gerbil brain ischemic damage through reduction of arachidonic acid liberation and accumulation. J Nutr Biochem 18 (2007) 297-304
    • (2007) J Nutr Biochem , vol.18 , pp. 297-304
    • Cao, D.1    Yang, B.2    Hou, L.3    Xu, J.4    Xue, R.5    Sun, L.6
  • 27
    • 35649023664 scopus 로고    scopus 로고
    • Detrimental effects of post-treatment of fatty acids on brain injury in ischemic rats
    • Yang D.Y., Pan H.C., Yen Y.J., Wang C.C., Chuang Y.H., Chen S.Y., et al. Detrimental effects of post-treatment of fatty acids on brain injury in ischemic rats. Neurotoxicology 28 (2007) 1220-1229
    • (2007) Neurotoxicology , vol.28 , pp. 1220-1229
    • Yang, D.Y.1    Pan, H.C.2    Yen, Y.J.3    Wang, C.C.4    Chuang, Y.H.5    Chen, S.Y.6
  • 28
    • 0032973031 scopus 로고    scopus 로고
    • Delayed administration of ethyl eicosapentate improves local cerebral blood flow and metabolism without affecting infarct volumes in the rat focal ischemic model
    • Katsumata T., Katayama Y., Obo R., Muramatsu H., Ohtori T., and Terashi A. Delayed administration of ethyl eicosapentate improves local cerebral blood flow and metabolism without affecting infarct volumes in the rat focal ischemic model. Eur J Pharmacol 372 (1999) 167-174
    • (1999) Eur J Pharmacol , vol.372 , pp. 167-174
    • Katsumata, T.1    Katayama, Y.2    Obo, R.3    Muramatsu, H.4    Ohtori, T.5    Terashi, A.6
  • 30
    • 0037185379 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids induce ischemic and epileptic tolerance
    • Blondeau N., Widmann C., Lazdunski M., and Heurteaux C. Polyunsaturated fatty acids induce ischemic and epileptic tolerance. Neuroscience 109 (2002) 231-241
    • (2002) Neuroscience , vol.109 , pp. 231-241
    • Blondeau, N.1    Widmann, C.2    Lazdunski, M.3    Heurteaux, C.4
  • 31
    • 0037199790 scopus 로고    scopus 로고
    • The effect of n-3 polyunsaturated fatty acid-rich diets on cognitive and cerebrovascular parameters in chronic cerebral hypoperfusion
    • de Wilde M.C., Farkas E., Gerrits M., Kiliaan A.J., and Luiten P.G.M. The effect of n-3 polyunsaturated fatty acid-rich diets on cognitive and cerebrovascular parameters in chronic cerebral hypoperfusion. Brain Res 947 (2002) 166-173
    • (2002) Brain Res , vol.947 , pp. 166-173
    • de Wilde, M.C.1    Farkas, E.2    Gerrits, M.3    Kiliaan, A.J.4    Luiten, P.G.M.5
  • 32
    • 10044224770 scopus 로고    scopus 로고
    • Protective effect of chronic ethyl docosahexaenoate administration on brain injury in ischemic gerbils
    • Cao D.H., Xu J.F., Xue R.H., Zheng W.F., and Liu Z.L. Protective effect of chronic ethyl docosahexaenoate administration on brain injury in ischemic gerbils. Pharmacol Biochem Behav 79 (2004) 651-659
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 651-659
    • Cao, D.H.1    Xu, J.F.2    Xue, R.H.3    Zheng, W.F.4    Liu, Z.L.5
  • 33
    • 27344437673 scopus 로고    scopus 로고
    • Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils
    • Cao D., Li M., Xue R., Zheng W., Liu Z., and Wang X. Chronic administration of ethyl docosahexaenoate decreases mortality and cerebral edema in ischemic gerbils. Life Sci 78 (2005) 74-81
    • (2005) Life Sci , vol.78 , pp. 74-81
    • Cao, D.1    Li, M.2    Xue, R.3    Zheng, W.4    Liu, Z.5    Wang, X.6
  • 34
    • 33645078417 scopus 로고    scopus 로고
    • Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion
    • Cao D., Zhou C., Sun L., Xue R., Xu J., and Liu Z. Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion. J Nutr Biochem 17 (2006) 234-241
    • (2006) J Nutr Biochem , vol.17 , pp. 234-241
    • Cao, D.1    Zhou, C.2    Sun, L.3    Xue, R.4    Xu, J.5    Liu, Z.6
  • 35
    • 33846575271 scopus 로고    scopus 로고
    • The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus
    • Bas O., Songur A., Sahin O., Mollaoglu H., Ozen O.A., Yaman M., et al. The protective effect of fish n-3 fatty acids on cerebral ischemia in rat hippocampus. Neurochem Int 50 (2007) 548-554
    • (2007) Neurochem Int , vol.50 , pp. 548-554
    • Bas, O.1    Songur, A.2    Sahin, O.3    Mollaoglu, H.4    Ozen, O.A.5    Yaman, M.6
  • 36
    • 23344439553 scopus 로고    scopus 로고
    • Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival
    • Akbar M., Calderon F., Wen Z., and Kim H.Y. Docosahexaenoic acid: a positive modulator of Akt signaling in neuronal survival. Proc Natl Acad Sci USA 102 (2005) 10858-10863
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 10858-10863
    • Akbar, M.1    Calderon, F.2    Wen, Z.3    Kim, H.Y.4
  • 37
    • 33644691914 scopus 로고    scopus 로고
    • Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells
    • Chen W., Esselman W.J., Jump D.B., and Busik J.V. Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci 46 (2005) 4342-4347
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 4342-4347
    • Chen, W.1    Esselman, W.J.2    Jump, D.B.3    Busik, J.V.4
  • 38
    • 33644875009 scopus 로고    scopus 로고
    • Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-β oligomers
    • Florent S., Malaplate-Armand C., Youssef I., Kriem B., Koziel V., Escanyé M.C., et al. Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-β oligomers. J Neurochem 96 (2006) 385-395
    • (2006) J Neurochem , vol.96 , pp. 385-395
    • Florent, S.1    Malaplate-Armand, C.2    Youssef, I.3    Kriem, B.4    Koziel, V.5    Escanyé, M.C.6
  • 39
    • 33746875974 scopus 로고    scopus 로고
    • Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway
    • German O.L., Insua M.F., Gentili C., Rotstein N.P., and Politi L.E. Docosahexaenoic acid prevents apoptosis of retina photoreceptors by activating the ERK/MAPK pathway. J Neurochem 98 (2006) 1507-1520
    • (2006) J Neurochem , vol.98 , pp. 1507-1520
    • German, O.L.1    Insua, M.F.2    Gentili, C.3    Rotstein, N.P.4    Politi, L.E.5
  • 40
    • 30544445874 scopus 로고    scopus 로고
    • Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats
    • Kao T.K., Ou Y.C., Kuo J.S., Chen W.Y., Liao S.L., Wu C.W., et al. Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats. Neurochem Int 48 (2006) 166-176
    • (2006) Neurochem Int , vol.48 , pp. 166-176
    • Kao, T.K.1    Ou, Y.C.2    Kuo, J.S.3    Chen, W.Y.4    Liao, S.L.5    Wu, C.W.6
  • 41
    • 0036249850 scopus 로고    scopus 로고
    • Oxidative stress involve in astrocytic alterations induced by manganese
    • Chen C.J., and Liao S.L. Oxidative stress involve in astrocytic alterations induced by manganese. Exp Neurol 175 (2002) 216-225
    • (2002) Exp Neurol , vol.175 , pp. 216-225
    • Chen, C.J.1    Liao, S.L.2
  • 42
    • 7644224458 scopus 로고    scopus 로고
    • Upregulation of RANTES gene expression in neuroglia by Japanese encephalitis virus infection
    • Chen C.J., Chen J.H., Chen S.Y., Liao S.L., and Raung S.L. Upregulation of RANTES gene expression in neuroglia by Japanese encephalitis virus infection. J Virol 78 (2004) 12107-12119
    • (2004) J Virol , vol.78 , pp. 12107-12119
    • Chen, C.J.1    Chen, J.H.2    Chen, S.Y.3    Liao, S.L.4    Raung, S.L.5
  • 43
    • 16944366242 scopus 로고    scopus 로고
    • Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia
    • Kondo T., Reaume A.G., Huang T.T., Carlson E., Murakami K., Chen S.F., et al. Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia. J Neurosci 17 (1997) 4180-4189
    • (1997) J Neurosci , vol.17 , pp. 4180-4189
    • Kondo, T.1    Reaume, A.G.2    Huang, T.T.3    Carlson, E.4    Murakami, K.5    Chen, S.F.6
  • 44
    • 0033782260 scopus 로고    scopus 로고
    • Caspase pathways, neuronal apoptosis, and CNS injury
    • Eldadah B.A., and Faden A.I. Caspase pathways, neuronal apoptosis, and CNS injury. J Neurotrauma 17 (2000) 811-829
    • (2000) J Neurotrauma , vol.17 , pp. 811-829
    • Eldadah, B.A.1    Faden, A.I.2
  • 46
    • 0036052311 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, inflammation and immunity
    • Calder P.C., and Grimble R.F. Polyunsaturated fatty acids, inflammation and immunity. Eur J Clin Nutr 56 (2002) S14-S19
    • (2002) Eur J Clin Nutr , vol.56
    • Calder, P.C.1    Grimble, R.F.2
  • 47
    • 0037971463 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic
    • Calder P.C. n-3 polyunsaturated fatty acids and inflammation: from molecular biology to the clinic. Lipids 38 (2003) 343-352
    • (2003) Lipids , vol.38 , pp. 343-352
    • Calder, P.C.1
  • 48
    • 0036192957 scopus 로고    scopus 로고
    • Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals
    • Kim G.W., Kondo T., Noshita N., and Chan P.H. Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals. Stroke 33 (2002) 809-815
    • (2002) Stroke , vol.33 , pp. 809-815
    • Kim, G.W.1    Kondo, T.2    Noshita, N.3    Chan, P.H.4
  • 49
    • 0021345093 scopus 로고
    • Eicosapentaenoic acid: effect on brain prostaglandins, cerebral blood flow and edema in ischemic gerbils
    • Black K.L., Hoff J.T., Radin N.S., and Deshmukh G.D. Eicosapentaenoic acid: effect on brain prostaglandins, cerebral blood flow and edema in ischemic gerbils. Stroke 15 (1984) 65-69
    • (1984) Stroke , vol.15 , pp. 65-69
    • Black, K.L.1    Hoff, J.T.2    Radin, N.S.3    Deshmukh, G.D.4
  • 50
    • 0242466233 scopus 로고    scopus 로고
    • Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal bcl-x(L) and bcl-2 expression through a fibroblast growth factor receptor 1- and ERK-dependent pathway
    • Desire L., Courtois Y., and Jeanny J.C. Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal bcl-x(L) and bcl-2 expression through a fibroblast growth factor receptor 1- and ERK-dependent pathway. J Neurochem 75 (2000) 151-163
    • (2000) J Neurochem , vol.75 , pp. 151-163
    • Desire, L.1    Courtois, Y.2    Jeanny, J.C.3
  • 51
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death
    • Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., and Korsmeyer S.J. Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces Bax and promotes cell death. Cell 80 (1995) 285-291
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.H.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 52
    • 0030803271 scopus 로고    scopus 로고
    • Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis
    • Adachi S., Cross A.R., Babior B.M., and Gottlieb R.A. Bcl-2 and the outer mitochondrial membrane in the inactivation of cytochrome c during Fas-mediated apoptosis. J Biol Chem 272 (1997) 21878-21882
    • (1997) J Biol Chem , vol.272 , pp. 21878-21882
    • Adachi, S.1    Cross, A.R.2    Babior, B.M.3    Gottlieb, R.A.4
  • 53
    • 33846857139 scopus 로고    scopus 로고
    • Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection
    • Bazan N.G. Omega-3 fatty acids, pro-inflammatory signaling and neuroprotection. Curr Opin Clin Nutr Metab Care 10 (2007) 136-141
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , pp. 136-141
    • Bazan, N.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.