A reliable procedure for comparison of antioxidants in rat brain homogenates

Journal of Pharmacological and Toxicological Methods

Volumn 39, Issue 3, 1998, Pages 155-162

  Callaway, Jennifer K ^a   Beart, Philip M ^a   Jarrott, Bevyn ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Antioxidant; Free radical scavengers; Iron dependent lipid peroxidation; Malondialdehyde; Thiobarbituric acid reacting substances

Indexed keywords

2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; 2,6 DI TERT BUTYL 4 [(ETHYLAMINO)METHYL]PHENOL; 21 [4 [5,6 BIS(DIETHYLAMINO) 2 PYRIDYL] 1 PIPERAZINYL] 16ALPHA METHYLPREGNA 1,4,9(11) TRIENE 3,20 DIONE; ANTIOXIDANT; BUTYLCRESOL; IDEBENONE; MALONALDEHYDE; SCAVENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TROLOX C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; BRAIN ISCHEMIA; IN VITRO STUDY; LIPID PEROXIDATION; MALE; NERVE CELL LESION; NONHUMAN; OXIDATIVE STRESS; RAT; TECHNIQUE;

ANIMALS; ANTIOXIDANTS; BRAIN; BRAIN CHEMISTRY; CHROMANS; DEFEROXAMINE; FERRIC COMPOUNDS; INHIBITORY CONCENTRATION 50; IRON CHELATING AGENTS; LIPID PEROXIDATION; MALE; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0032049505     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(98)00022-7     Document Type: Article

References (46)

1. Aisen P., Listowsky I. Iron transport and storage proteins. Annu Rev Biochem. 49:1980;357-393.
2. Auroma O.I., Halliwell B., Laughton M.J., Quinlan G.J., Gutteridge J.M.C. The mechanism of initiation of lipid peroxidation. Evidence against a requirement for an iron(II)-iron(III) complex. Biochem J. 258:1989;617-620.
3. Barclay L.R.C., Locke S.J., Mac Neil J.M. Antioxidation in micelles. Synergism of vitamin C with lipid-soluble vitamin E and water-soluble Trolox. Can J Chem. 63:1985;366-374.
4. Barkai A.I., Durkin M., Dwork A.J., Nelson H.D. Autoradiographic study of iron binding sites in the rat brain distribution and relationship to aging . J Neurosci Res. 29:1991;390-395.
5. Ben-Shachar D., Eshel G., Finberg J.P.M., Youdim M. The iron-chelator desferroxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigral striatal dopamine neurons. Neurochemistry. 56:1991;1441-1444.
6. Biemond P., Swaak A.J.G., Beindorff C.M., Koster J.F. Superoxide-dependent and independent mechanisms of iron mobilization from ferritin by xanthine oxidase. Implications for oxygen-free-radical-induced tissue destruction during ischaemia and inflammation. Biochem J. 239:1986;169-173.
7. Buege J.A., Aust S.D. Microsomal lipid peroxidation. Methods Enzymol. 52:1978;302-310.
8. Boehme D.H., Kosecki R., Carsson S., Stern F., Marks N. Lipoperoxidation in human and rat brain tissue developmental and regional studies . Brain Res. 136:1977;11-21.
9. Braughler J.M., Duncan L.A., Chase R.L. The involvement of iron in lipid peroxidation importance of ferric to ferrous ratios in initiation . J Biol Chem. 261:1986;10282-10289.
10. Braughler J.M., Pregenzer J.F., Chase R.L., Duncan L.A., Jacobsen E.J., McCall J.M. Novel 21-amino steroids as potent inhibitors of iron-dependent lipid peroxidation. J Biol Chem. 262:1987;10438-10440.
11. Braughler J.M., Burton P.S., Chase R.L., Pregenzer J.F., Jacobsen E.J., Vandoornik F.J., Tustin J.M., Ayer D.E., Bundy G.L. Novel membrane localised iron chelators as inhibitors or iron-dependent lipid peroxidation. Biochem Pharmacol. 37:1988;3853-3860.
12. Clemens J.A., Saunders R.D., Ho P.P., Phebus L.A., Panetta J.A. The antioxidant LY231617 reduces global ischemic neuronal injury in rats. Stroke. 24:1993;716-723.
13. Cort W.M. Antioxidant activity of tocopherols, ascorbyl palmitate, and ascorbic acid and their mode of action. JAOCS. 51:1974;321.
14. Coyle J.T., Puttfarken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science. 262:1993;689-695.
15. Doba T., Burton G.W., Ingold K.U. Antioxidant and co-oxidant activity of vitamin C. The effect of vitamin C, alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multiamellar phospholipid liposomes. Biochim Biophys Acta. 835:1985;298-303.
16. Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products malondialdehyde and 4-hydroxynonenal . Methods Enzymol. 186:1990;407-421.
17. Fraga C.G., Leibovitz B.E., Tappel A.L. Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices characterisation and comparison with homogenates and microsomes . Free Rad Biol Chem. 4:1988;155-161.
18. Gutteridge J.M.C. Aspects to consider when detecting and measuring lipid peroxidation. Free Rad Biol Med. 1:1986;173-184.
19. Gutteridge J.M.C., Tickner T.R. The characterisation of thiobarbituric acid reactivity in human plasma and urine. Anal Biochem. 91:1978;250-257.
20. Gutteridge J.M.C., Richmond R., Halliwell B. Inhibition of the iron-catalysed formation of hydroxyl radicals from superoxide and a lipid peroxidation by desferrioxamine. Biochem J. 184:1979;469-472.
21. Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelators is it a mechanism for hydroxyl radical production in biochemical systems? FEBS Lett. 92:1978;321-326.
22. Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem. 59:1992;1609-1623.
23. Halliwell B, Gutteridge JMC (1988) Iron as a biological pro-oxidant. ISI Atlas of Science: Biochemistry Vol. 1 48-52.
24. Halliwell B., Gutteridge J.M.C. The importance of free radicals and catalytic metal ions in human diseases. Mol Aspects Med. 8:1985;89-193.
25. Janero D.R. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Rad Biol Med. 9:1990;515-540.
26. Jellinger K., Kienzl E., Rumpelmair G., Riederer P., Stachelberger H., Ben-Shachar D., Youdim M.B.M. Iron-melanin complex in substantia nigra of Parkinsonian brains an x-ray microanalysis . J Neurochem. 59:1992;1168-1171.
27. Koster J.F., Slee R.G. Ferritin, a physiological iron donor for microsomal lipid peroxidation. FEBS Lett. 199:1986;85-88.
28. Kukielka E., Cederbaum A.I. Ferritin stimulation of lipid peroxidation by microsomes after chronic ethanol treatment role of cytochrome P4502E1 . Arch Biochem Biophys. 332:1996;121-127.
29. Lentner C. Documenta Geigy Scientific Tables. 8th ed. 1992;210-215 Ciba Geigy, Basel.
30. Ludbrook J. Comparing methods of measurement. Clin Exp Pharmacol Physiol. 24:1997;193-203.
31. Mickle DAG, Li R-K, Weisel RD, Birnbaum PL, Wu T-W, Jackowski G, Madonik MM, Burton GW, Ingold KU (1989) Myocardial salvage with Trolox and ascorbic acid for an acute evolving infarction. Ann Thorac Surg 47:564-557.
32. Minotti G., Aust S.D. The role of iron in the initiation of lipid peroxidation. Chem Phys Lipid. 44:1987;191-208.
33. Minotti G., Aust S.D. The requirement for iron (III) in the initiation of lipid peroxidation by iron (II) and hydrogen peroxide. J Biol Chem. 262:1987;1098-1104.
34. Narla R.S., Rao M.N.A. Scavenging of free-radicals and inhibition of lipid peroxidation by 3-phenylsydnone. J Pharm Pharmacol. 47:1994;623-625.
35. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 95:1979;351-358.
36. Olanow C.W. A rationale for monoamine oxidase inhibition as neuroprotective therapy for Parkinson's disease. Mov Disorders. 8:1993;S1-S7.
37. Placer Z.A., Cushman L.L., Johnson B.C. Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Anal Biochem. 16:1966;359-364.
38. Puppo A., Halliwell B. Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is hemoglobin a biological Fenton reagent? Biochem J. 249:1988;185-190.
39. Scott J.W., Cort W.M., Harley H., Parrish D.R., Saucy G. 6-Hydroxychroman-2-carboxylic acids novel antioxidants . JAOCS. 51:1974;250.
40. Siesjo B.K., Agardh C.D., Bengtsson F. Free radicals and brain damage. Cerebrovasc Brain Metab Rev. 1:1989;165-211.
41. Suno M., Nagaoka A. Inhibition of lipid peroxidation by a novel compound, idebenone (CV-2619). Japan J Pharmacol. 35:1984;196-198.
42. Tadolini B., Hakim G. The mechanism of iron (III) stimulation of lipid peroxidation. Free Rad Res. 25:1996;221-227.
43. Tarladgis B.G., Pearson A.M., Dugan L.R. Jr. The chemistry of the 2-thiobarbituric acid test for the determination of oxidative rancidity in foods. I. Some important side reactions. J Am Oil Chem Soc. 39:1962;34-39.
44. Tien B., Svingen B.A., Aust S.D. An investigation into the role of hydroxyl radical in xanthine oxidase-dependent lipid peroxidation. Arch Biochem Biophys. 216:1982;142-151.
45. Willmore L.J., Triggs W.J. Iron-induced lipid peroxidation and brain injury responses. Int J Dev Neurosci. 9:1991;175-191.
46. 2+)-ATPase against iron-induced inhibition. Eur J Pharmacol (Mol Pharmacol). 290:1995;133-139.