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Volumn 5, Issue 5, 2013, Pages 683-697

Cardiac regeneration: Current therapies-future concepts

Author keywords

Myocardial infarction; Regenerative medicine; Reprogramming; Stem cells; Tissue engineering

Indexed keywords

ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 84888389693     PISSN: 20721439     EISSN: 20776624     Source Type: Journal    
DOI: 10.3978/j.issn.2072-1439.2013.08.71     Document Type: Review
Times cited : (103)

References (119)
  • 1
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics--2013 update: a report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation 2013;127:e6-e245.
    • (2013) Circulation , vol.127
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 84878722569 scopus 로고    scopus 로고
    • Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics
    • Bartunek J, Behfar A, Dolatabadi D, et al. Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified biologics. J Am Coll Cardiol 2013;61:2329-38.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 2329-2338
    • Bartunek, J.1    Behfar, A.2    Dolatabadi, D.3
  • 3
    • 84864453582 scopus 로고    scopus 로고
    • Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis
    • Jeevanantham V, Butler M, Saad A, et al. Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis. Circulation 2012;126:551-68.
    • (2012) Circulation , vol.126 , pp. 551-568
    • Jeevanantham, V.1    Butler, M.2    Saad, A.3
  • 5
    • 79956334658 scopus 로고    scopus 로고
    • Heart regeneration
    • Laflamme MA, Murry CE. Heart regeneration. Nature 2011;473:326-35.
    • (2011) Nature , vol.473 , pp. 326-335
    • Laflamme, M.A.1    Murry, C.E.2
  • 6
    • 84874409958 scopus 로고    scopus 로고
    • Early cardiac retention of administered stem cells determines clinical efficacy of cell therapy in patients with dilated cardiomyopathy
    • Assmus B, Zeiher AM. Early cardiac retention of administered stem cells determines clinical efficacy of cell therapy in patients with dilated cardiomyopathy. Circ Res 2013;112:6-8.
    • (2013) Circ Res , vol.112 , pp. 6-8
    • Assmus, B.1    Zeiher, A.M.2
  • 7
    • 0035943333 scopus 로고    scopus 로고
    • Intracoronary, human autologous stem cell transplantation for myocardial regeneration following myocardial infarction
    • Strauer BE, Brehm M, Zeus T, et al. Intracoronary, human autologous stem cell transplantation for myocardial regeneration following myocardial infarction. Dtsch Med Wochenschr 2001;126:932-8.
    • (2001) Dtsch Med Wochenschr , vol.126 , pp. 932-938
    • Strauer, B.E.1    Brehm, M.2    Zeus, T.3
  • 8
    • 0037417501 scopus 로고    scopus 로고
    • Autologous bone-marrow stem-cell transplantation for myocardial regeneration
    • Stamm C, Westphal B, Kleine HD, et al. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003;361:45-6.
    • (2003) Lancet , vol.361 , pp. 45-46
    • Stamm, C.1    Westphal, B.2    Kleine, H.D.3
  • 9
    • 80052376468 scopus 로고    scopus 로고
    • 10 years of intracoronary and intramyocardial bone marrow stem cell therapy of the heart: from the methodological origin to clinical practice
    • Strauer BE, Steinhoff G. 10 years of intracoronary and intramyocardial bone marrow stem cell therapy of the heart: from the methodological origin to clinical practice. J Am Coll Cardiol 2011;58:1095-104.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 1095-1104
    • Strauer, B.E.1    Steinhoff, G.2
  • 10
    • 72649085884 scopus 로고    scopus 로고
    • Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial.
    • Meyer GP, Wollert KC, Lotz J, et al. Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial. Eur Heart J 2009;30:2978-84.
    • (2009) Eur Heart J , vol.30 , pp. 2978-2984
    • Meyer, G.P.1    Wollert, K.C.2    Lotz, J.3
  • 11
    • 76549111138 scopus 로고    scopus 로고
    • Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction
    • Assmus B, Rolf A, Erbs S, et al. Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction. Circ Heart Fail 2010;3:89-96.
    • (2010) Circ Heart Fail , vol.3 , pp. 89-96
    • Assmus, B.1    Rolf, A.2    Erbs, S.3
  • 12
    • 80054721891 scopus 로고    scopus 로고
    • Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy
    • Leistner DM, Fischer-Rasokat U, Honold J, et al. Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy. Clin Res Cardiol 2011;100:925-34.
    • (2011) Clin Res Cardiol , vol.100 , pp. 925-934
    • Leistner, D.M.1    Fischer-Rasokat, U.2    Honold, J.3
  • 13
    • 84876302976 scopus 로고    scopus 로고
    • Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial.
    • Assmus B, Walter DH, Seeger FH, et al. Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial. JAMA 2013;309:1622-31.
    • (2013) JAMA , vol.309 , pp. 1622-1631
    • Assmus, B.1    Walter, D.H.2    Seeger, F.H.3
  • 14
    • 84856193410 scopus 로고    scopus 로고
    • First experience in humans using adipose tissue-derived regenerative cells in the treatment of patients with ST-segment elevation myocardial infarction
    • Houtgraaf JH, den Dekker WK, van Dalen BM, et al. First experience in humans using adipose tissue-derived regenerative cells in the treatment of patients with ST-segment elevation myocardial infarction. J Am Coll Cardiol 2012;59:539-40.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 539-540
    • Houtgraaf, J.H.1    den Dekker, W.K.2    van Dalen, B.M.3
  • 15
    • 84858019974 scopus 로고    scopus 로고
    • Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial
    • Makkar RR, Smith RR, Cheng K, et al. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 2012;379:895-904.
    • (2012) Lancet , vol.379 , pp. 895-904
    • Makkar, R.R.1    Smith, R.R.2    Cheng, K.3
  • 16
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial
    • Bolli R, Chugh AR, D'Amario D, et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 2011;378:1847-57.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D'Amario, D.3
  • 17
    • 84866458852 scopus 로고    scopus 로고
    • Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance
    • Chugh AR, Beache GM, Loughran JH, et al. Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance. Circulation 2012;126:S54-64.
    • (2012) Circulation , vol.126
    • Chugh, A.R.1    Beache, G.M.2    Loughran, J.H.3
  • 18
    • 78349233886 scopus 로고    scopus 로고
    • Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): a pilot, randomized, placebo-controlled study
    • Taniguchi N, Nakamura T, Sawada T, et al. Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): a pilot, randomized, placebo-controlled study. Circ J 2010;74:2365-71.
    • (2010) Circ J , vol.74 , pp. 2365-2371
    • Taniguchi, N.1    Nakamura, T.2    Sawada, T.3
  • 19
    • 79955396662 scopus 로고    scopus 로고
    • A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure
    • Bergmann MW, Haufe S, von Knobelsdorff-Brenkenhoff F, et al. A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure. Eur J Heart Fail 2011;13:560-8.
    • (2011) Eur J Heart Fail , vol.13 , pp. 560-568
    • Bergmann, M.W.1    Haufe, S.2    von Knobelsdorff-Brenkenhoff, F.3
  • 20
    • 77957229327 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI: results of the single-blind, randomized, placebo-controlled multicentre STem cEll Mobilization in Acute Myocardial Infarction (STEM-AMI) Trial
    • Achilli F, Malafronte C, Lenatti L, et al. Granulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI: results of the single-blind, randomized, placebo-controlled multicentre STem cEll Mobilization in Acute Myocardial Infarction (STEM-AMI) Trial. Eur J Heart Fail 2010;12:1111-21.
    • (2010) Eur J Heart Fail , vol.12 , pp. 1111-1121
    • Achilli, F.1    Malafronte, C.2    Lenatti, L.3
  • 21
    • 84871225685 scopus 로고    scopus 로고
    • Five-year results of intracoronary infusion of the mobilized peripheral blood stem cells by granulocyte colony-stimulating factor in patients with myocardial infarction.
    • Kang HJ, Kim MK, Lee HY, et al. Five-year results of intracoronary infusion of the mobilized peripheral blood stem cells by granulocyte colony-stimulating factor in patients with myocardial infarction. Eur Heart J 2012;33:3062-9.
    • (2012) Eur Heart J , vol.33 , pp. 3062-3069
    • Kang, H.J.1    Kim, M.K.2    Lee, H.Y.3
  • 22
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-5.
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 23
    • 0034988491 scopus 로고    scopus 로고
    • Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
    • Jackson KA, Majka SM, Wang H, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest 2001;107:1395-402.
    • (2001) J Clin Invest , vol.107 , pp. 1395-1402
    • Jackson, K.A.1    Majka, S.M.2    Wang, H.3
  • 24
    • 33947509872 scopus 로고    scopus 로고
    • Non-resident stem cell populations in regenerative cardiac medicine
    • Franco D, Moreno N, Ruiz-Lozano P. Non-resident stem cell populations in regenerative cardiac medicine. Cell Mol Life Sci 2007;64:683-91.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 683-691
    • Franco, D.1    Moreno, N.2    Ruiz-Lozano, P.3
  • 26
    • 0035067539 scopus 로고    scopus 로고
    • Multilineage cells from human adipose tissue: implications for cell-based therapies
    • Zuk PA, Zhu M, Mizuno H, et al. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 2001;7:211-28.
    • (2001) Tissue Eng , vol.7 , pp. 211-228
    • Zuk, P.A.1    Zhu, M.2    Mizuno, H.3
  • 27
    • 74049122788 scopus 로고    scopus 로고
    • Mesenchymal stromal cells for cardiovascular repair: current status and future challenges
    • Mathiasen AB, Haack-Sorensen M, Kastrup J. Mesenchymal stromal cells for cardiovascular repair: current status and future challenges. Future Cardiol 2009;5:605-17.
    • (2009) Future Cardiol , vol.5 , pp. 605-617
    • Mathiasen, A.B.1    Haack-Sorensen, M.2    Kastrup, J.3
  • 28
    • 84872530323 scopus 로고    scopus 로고
    • Stem cell therapy for the treatment of acute myocardial infarction and chronic ischemic heart disease
    • Donndorf P, Strauer BE, Haverich A, et al. Stem cell therapy for the treatment of acute myocardial infarction and chronic ischemic heart disease. Curr Pharm Biotechnol 2013;14:12-9.
    • (2013) Curr Pharm Biotechnol , vol.14 , pp. 12-19
    • Donndorf, P.1    Strauer, B.E.2    Haverich, A.3
  • 29
    • 84871209770 scopus 로고    scopus 로고
    • Regenerating cardiac cells: insights from the bench and the clinic
    • Teng M, Zhao X, Huang Y. Regenerating cardiac cells: insights from the bench and the clinic. Cell Tissue Res 2012;350:189-97.
    • (2012) Cell Tissue Res , vol.350 , pp. 189-197
    • Teng, M.1    Zhao, X.2    Huang, Y.3
  • 30
    • 78649319271 scopus 로고    scopus 로고
    • Promises and pitfalls in cell replacement therapy for heart failure
    • Krane M, Wernet O, Wu SM. Promises and pitfalls in cell replacement therapy for heart failure. Drug Discov Today Dis Mech 2010;7:e109-e115.
    • (2010) Drug Discov Today Dis Mech , vol.7
    • Krane, M.1    Wernet, O.2    Wu, S.M.3
  • 31
    • 84866325647 scopus 로고    scopus 로고
    • Rationale and design of the first randomized, double-blind, placebo-controlled trial of intramyocardial injection of autologous bone-marrow derived mesenchymal stromal cells in chronic ischemic heart failure (MSC-HF Trial)
    • Mathiasen AB, Jorgensen E, Qayyum AA, et al. Rationale and design of the first randomized, double-blind, placebo-controlled trial of intramyocardial injection of autologous bone-marrow derived mesenchymal stromal cells in chronic ischemic heart failure (MSC-HF Trial). Am Heart J 2012;164:285-91.
    • (2012) Am Heart J , vol.164 , pp. 285-291
    • Mathiasen, A.B.1    Jorgensen, E.2    Qayyum, A.A.3
  • 33
    • 79960993428 scopus 로고    scopus 로고
    • Cell-based cardiovascular repair and regeneration in acute myocardial infarction and chronic ischemic cardiomyopathy-current status and future developments
    • Templin C, Luscher TF, Landmesser U. Cell-based cardiovascular repair and regeneration in acute myocardial infarction and chronic ischemic cardiomyopathy-current status and future developments. Int J Dev Biol 2011;55:407-17.
    • (2011) Int J Dev Biol , vol.55 , pp. 407-417
    • Templin, C.1    Luscher, T.F.2    Landmesser, U.3
  • 34
    • 84863110323 scopus 로고    scopus 로고
    • Validating intramyocardial bone marrow stem cell therapy in combination with coronary artery bypass grafting, the PERFECT Phase III randomized multicenter trial: study protocol for a randomized controlled trial
    • Donndorf P, Kaminski A, Tiedemann G, et al. Validating intramyocardial bone marrow stem cell therapy in combination with coronary artery bypass grafting, the PERFECT Phase III randomized multicenter trial: study protocol for a randomized controlled trial. Trials 2012;13:99.
    • (2012) Trials , vol.13 , pp. 99
    • Donndorf, P.1    Kaminski, A.2    Tiedemann, G.3
  • 35
    • 33644616093 scopus 로고    scopus 로고
    • Plasticity of human adipose stem cells toward endothelial cells and cardiomyocytes
    • Fraser JK, Schreiber R, Strem B, et al. Plasticity of human adipose stem cells toward endothelial cells and cardiomyocytes. Nat Clin Pract Cardiovasc Med 2006;3 Suppl 1:S33-7.
    • (2006) Nat Clin Pract Cardiovasc Med , vol.3 SUPPL.
    • Fraser, J.K.1    Schreiber, R.2    Strem, B.3
  • 36
    • 35948999615 scopus 로고    scopus 로고
    • Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction
    • Valina C, Pinkernell K, Song YH, et al. Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction. Eur Heart J 2007;28:2667-77.
    • (2007) Eur Heart J , vol.28 , pp. 2667-2677
    • Valina, C.1    Pinkernell, K.2    Song, Y.H.3
  • 37
    • 77957350400 scopus 로고    scopus 로고
    • Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease
    • Beohar N, Rapp J, Pandya S, et al. Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease. J Am Coll Cardiol 2010;56:1287-97.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 1287-1297
    • Beohar, N.1    Rapp, J.2    Pandya, S.3
  • 38
    • 80052651886 scopus 로고    scopus 로고
    • Erythropoietin as a cardioprotective agent: down but not out
    • Opie LH. Erythropoietin as a cardioprotective agent: down but not out. Heart 2011;97:1537-9.
    • (2011) Heart , vol.97 , pp. 1537-1539
    • Opie, L.H.1
  • 39
    • 33845225092 scopus 로고    scopus 로고
    • Protective effects of erythropoietin in cardiac ischemia: from bench to bedside
    • Lipsic E, Schoemaker RG, van der Meer P, et al. Protective effects of erythropoietin in cardiac ischemia: from bench to bedside. J Am Coll Cardiol 2006;48:2161-7.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2161-2167
    • Lipsic, E.1    Schoemaker, R.G.2    van der Meer, P.3
  • 40
    • 34848832453 scopus 로고    scopus 로고
    • Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization.
    • Westenbrink BD, Lipsic E, van der Meer P, et al. Erythropoietin improves cardiac function through endothelial progenitor cell and vascular endothelial growth factor mediated neovascularization. Eur Heart J 2007;28:2018-27.
    • (2007) Eur Heart J , vol.28 , pp. 2018-2027
    • Westenbrink, B.D.1    Lipsic, E.2    van der Meer, P.3
  • 41
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats.
    • Moon C, Krawczyk M, Ahn D, et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci U S A 2003;100:11612-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11612-11617
    • Moon, C.1    Krawczyk, M.2    Ahn, D.3
  • 42
    • 84868608614 scopus 로고    scopus 로고
    • Erythropoietin treatment in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials.
    • Gao D, Ning N, Niu X, et al. Erythropoietin treatment in patients with acute myocardial infarction: a meta-analysis of randomized controlled trials. Am Heart J 2012;164:715-727.e1.
    • (2012) Am Heart J , vol.164
    • Gao, D.1    Ning, N.2    Niu, X.3
  • 43
    • 77957243198 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor in cardiac repair: time for a reappraisal?
    • Janssens SP. Granulocyte colony-stimulating factor in cardiac repair: time for a reappraisal? Eur J Heart Fail 2010;12:1021-3.
    • (2010) Eur J Heart Fail , vol.12 , pp. 1021-1023
    • Janssens, S.P.1
  • 44
    • 4644247808 scopus 로고    scopus 로고
    • Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization.
    • Ohtsuka M, Takano H, Zou Y, et al. Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. FASEB J 2004;18:851-3.
    • (2004) FASEB J , vol.18 , pp. 851-853
    • Ohtsuka, M.1    Takano, H.2    Zou, Y.3
  • 45
    • 28744438835 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils.
    • Ohki Y, Heissig B, Sato Y, et al. Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils. FASEB J 2005;19:2005-7.
    • (2005) FASEB J , vol.19 , pp. 2005-2007
    • Ohki, Y.1    Heissig, B.2    Sato, Y.3
  • 46
    • 42549086302 scopus 로고    scopus 로고
    • Cardiovascular events and re-stenosis following administration of G-CSF in acute myocardial infarction: systematic review and meta-analysis
    • Ince H, Valgimigli M, Petzsch M, et al. Cardiovascular events and re-stenosis following administration of G-CSF in acute myocardial infarction: systematic review and meta-analysis. Heart 2008;94:610-6.
    • (2008) Heart , vol.94 , pp. 610-616
    • Ince, H.1    Valgimigli, M.2    Petzsch, M.3
  • 47
    • 47649087935 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials
    • Abdel-Latif A, Bolli R, Zuba-Surma EK, et al. Granulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials. Am Heart J 2008;156:216-226.e9.
    • (2008) Am Heart J , vol.156
    • Abdel-Latif, A.1    Bolli, R.2    Zuba-Surma, E.K.3
  • 48
    • 84886284739 scopus 로고    scopus 로고
    • Antidiabetic gliptins in combination with G-CSF enhances myocardial function and survival after acute myocardial infarction
    • Theiss HD, Gross L, Vallaster M, et al. Antidiabetic gliptins in combination with G-CSF enhances myocardial function and survival after acute myocardial infarction. Int J Cardiol 2013;168:3359-69.
    • (2013) Int J Cardiol , vol.168 , pp. 3359-3369
    • Theiss, H.D.1    Gross, L.2    Vallaster, M.3
  • 49
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006;368:1696-705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 50
    • 28844482322 scopus 로고    scopus 로고
    • Van Dyck K, et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses
    • Herman GA, Stevens C, Van Dyck K, et al. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin Pharmacol Ther 2005;78:675-88.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 675-688
    • Herman, G.A.1    Stevens, C.2
  • 51
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, et al. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 2008;103:1204-19.
    • (2008) Circ Res , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3
  • 52
    • 84858076545 scopus 로고    scopus 로고
    • Cardiac regeneration: messages from CADUCEUS
    • Siu CW, Tse HF. Cardiac regeneration: messages from CADUCEUS. Lancet 2012;379:870-1.
    • (2012) Lancet , vol.379 , pp. 870-871
    • Siu, C.W.1    Tse, H.F.2
  • 53
    • 33847145871 scopus 로고    scopus 로고
    • Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens
    • Smith RR, Barile L, Cho HC, et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 2007;115:896-908.
    • (2007) Circulation , vol.115 , pp. 896-908
    • Smith, R.R.1    Barile, L.2    Cho, H.C.3
  • 54
    • 70349661889 scopus 로고    scopus 로고
    • Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy
    • 7 p following 1083
    • Johnston PV, Sasano T, Mills K, et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009;120:1075-83, 7 p following 1083.
    • (2009) Circulation , vol.120 , Issue.7 , pp. 1075-83
    • Johnston, P.V.1    Sasano, T.2    Mills, K.3
  • 55
    • 84863230134 scopus 로고    scopus 로고
    • Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells
    • Li TS, Cheng K, Malliaras K, et al. Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 2012;59:942-53.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 942-953
    • Li, T.S.1    Cheng, K.2    Malliaras, K.3
  • 56
    • 10744228523 scopus 로고    scopus 로고
    • Adult cardiac stem cells are multipotent and support myocardial regeneration
    • Beltrami AP, Barlucchi L, Torella D, et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003;114:763-76.
    • (2003) Cell , vol.114 , pp. 763-776
    • Beltrami, A.P.1    Barlucchi, L.2    Torella, D.3
  • 57
    • 84873806643 scopus 로고    scopus 로고
    • Regenerating new heart with stem cells
    • Anversa P, Kajstura J, Rota M, et al. Regenerating new heart with stem cells. J Clin Invest 2013;123:62-70.
    • (2013) J Clin Invest , vol.123 , pp. 62-70
    • Anversa, P.1    Kajstura, J.2    Rota, M.3
  • 59
    • 74949120679 scopus 로고    scopus 로고
    • Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction
    • Tang XL, Rokosh G, Sanganalmath SK, et al. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 2010;121:293-305.
    • (2010) Circulation , vol.121 , pp. 293-305
    • Tang, X.L.1    Rokosh, G.2    Sanganalmath, S.K.3
  • 60
    • 77950890007 scopus 로고    scopus 로고
    • Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice
    • Chimenti I, Smith RR, Li TS, et al. Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 2010;106:971-80.
    • (2010) Circ Res , vol.106 , pp. 971-980
    • Chimenti, I.1    Smith, R.R.2    Li, T.S.3
  • 61
    • 79960485562 scopus 로고    scopus 로고
    • Bioengineering heart muscle: a paradigm for regenerative medicine
    • Vunjak-Novakovic G, Lui KO, Tandon N, et al. Bioengineering heart muscle: a paradigm for regenerative medicine. Annu Rev Biomed Eng 2011;13:245-67.
    • (2011) Annu Rev Biomed Eng , vol.13 , pp. 245-267
    • Vunjak-Novakovic, G.1    Lui, K.O.2    Tandon, N.3
  • 62
    • 53549131225 scopus 로고    scopus 로고
    • Systems approaches to preventing transplanted cell death in cardiac repair
    • Robey TE, Saiget MK, Reinecke H, et al. Systems approaches to preventing transplanted cell death in cardiac repair. J Mol Cell Cardiol 2008;45:567-81.
    • (2008) J Mol Cell Cardiol , vol.45 , pp. 567-581
    • Robey, T.E.1    Saiget, M.K.2    Reinecke, H.3
  • 63
    • 79958782230 scopus 로고    scopus 로고
    • Cardiac cell therapy: where we've been, where we are, and where we should be headed
    • Malliaras K, Marban E. Cardiac cell therapy: where we've been, where we are, and where we should be headed. Br Med Bull 2011;98:161-85.
    • (2011) Br Med Bull , vol.98 , pp. 161-185
    • Malliaras, K.1    Marban, E.2
  • 64
    • 84864298142 scopus 로고    scopus 로고
    • Stem cell therapy for cardiac disease
    • Bernstein HS, Srivastava D. Stem cell therapy for cardiac disease. Pediatr Res 2012;71:491-9.
    • (2012) Pediatr Res , vol.71 , pp. 491-499
    • Bernstein, H.S.1    Srivastava, D.2
  • 65
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 66
    • 0000155376 scopus 로고
    • The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles
    • Gurdon JB. The developmental capacity of nuclei taken from intestinal epithelium cells of feeding tadpoles. J Embryol Exp Morphol 1962;10:622-40.
    • (1962) J Embryol Exp Morphol , vol.10 , pp. 622-640
    • Gurdon, J.B.1
  • 67
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-72.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 68
    • 84858010940 scopus 로고    scopus 로고
    • Stem cell based therapy--where are we going?
    • Ilic D, Polak J. Stem cell based therapy--where are we going? Lancet 2012;379:877-8.
    • (2012) Lancet , vol.379 , pp. 877-878
    • Ilic, D.1    Polak, J.2
  • 69
    • 84862907693 scopus 로고    scopus 로고
    • Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming
    • Burridge PW, Keller G, Gold JD, et al. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell 2012;10:16-28.
    • (2012) Cell Stem Cell , vol.10 , pp. 16-28
    • Burridge, P.W.1    Keller, G.2    Gold, J.D.3
  • 70
    • 33750456216 scopus 로고    scopus 로고
    • Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages
    • Kattman SJ, Huber TL, Keller GM. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev Cell 2006;11:723-32.
    • (2006) Dev Cell , vol.11 , pp. 723-732
    • Kattman, S.J.1    Huber, T.L.2    Keller, G.M.3
  • 71
    • 33845457194 scopus 로고    scopus 로고
    • Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification
    • Moretti A, Caron L, Nakano A, et al. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 2006;127:1151-65.
    • (2006) Cell , vol.127 , pp. 1151-1165
    • Moretti, A.1    Caron, L.2    Nakano, A.3
  • 72
    • 33845442108 scopus 로고    scopus 로고
    • Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart
    • Wu SM, Fujiwara Y, Cibulsky SM, et al. Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 2006;127:1137-50.
    • (2006) Cell , vol.127 , pp. 1137-1150
    • Wu, S.M.1    Fujiwara, Y.2    Cibulsky, S.M.3
  • 73
    • 84864696029 scopus 로고    scopus 로고
    • Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.
    • Islas JF, Liu Y, Weng KC, et al. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A 2012;109:13016-21.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 13016-13021
    • Islas, J.F.1    Liu, Y.2    Weng, K.C.3
  • 74
    • 0037326459 scopus 로고    scopus 로고
    • Long-term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells
    • Min JY, Yang Y, Sullivan MF, et al. Long-term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells. J Thorac Cardiovasc Surg 2003;125:361-9.
    • (2003) J Thorac Cardiovasc Surg , vol.125 , pp. 361-369
    • Min, J.Y.1    Yang, Y.2    Sullivan, M.F.3
  • 75
    • 29444434297 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types
    • Singla DK, Hacker TA, Ma L, et al. Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types. J Mol Cell Cardiol 2006;40:195-200.
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 195-200
    • Singla, D.K.1    Hacker, T.A.2    Ma, L.3
  • 76
    • 68249094138 scopus 로고    scopus 로고
    • Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells
    • Nelson TJ, Martinez-Fernandez A, Yamada S, et al. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 2009;120:408-16.
    • (2009) Circulation , vol.120 , pp. 408-416
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Yamada, S.3
  • 77
    • 80053544666 scopus 로고    scopus 로고
    • Induced pluripotent stem (iPS) cells repair and regenerate infarcted myocardium
    • Singla DK, Long X, Glass C, et al. Induced pluripotent stem (iPS) cells repair and regenerate infarcted myocardium. Mol Pharm 2011;8:1573-81.
    • (2011) Mol Pharm , vol.8 , pp. 1573-1581
    • Singla, D.K.1    Long, X.2    Glass, C.3
  • 78
    • 84879261618 scopus 로고    scopus 로고
    • Intramyocardial injection of pig pluripotent stem cells improves left ventricular function and perfusion: a study in a porcine model of acute myocardial infarction
    • Li X, Zhang F, Song G, et al. Intramyocardial injection of pig pluripotent stem cells improves left ventricular function and perfusion: a study in a porcine model of acute myocardial infarction. PLoS One 2013;8:e66688.
    • (2013) PLoS One , vol.8
    • Li, X.1    Zhang, F.2    Song, G.3
  • 79
    • 70350514702 scopus 로고    scopus 로고
    • Cardiac applications for human pluripotent stem cells
    • Shiba Y, Hauch KD, Laflamme MA. Cardiac applications for human pluripotent stem cells. Curr Pharm Des 2009;15:2791-806.
    • (2009) Curr Pharm Des , vol.15 , pp. 2791-2806
    • Shiba, Y.1    Hauch, K.D.2    Laflamme, M.A.3
  • 80
    • 35548974727 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts
    • Caspi O, Huber I, Kehat I, et al. Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. J Am Coll Cardiol 2007;50:1884-93.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1884-1893
    • Caspi, O.1    Huber, I.2    Kehat, I.3
  • 81
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 2007;25:1015-24.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 82
    • 73849107793 scopus 로고    scopus 로고
    • Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes
    • van Laake LW, van Donselaar EG, Monshouwer-Kloots J, et al. Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cell Mol Life Sci 2010;67:277-90.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 277-290
    • van Laake, L.W.1    van Donselaar, E.G.2    Monshouwer-Kloots, J.3
  • 83
    • 79955572417 scopus 로고    scopus 로고
    • Harnessing the potential of induced pluripotent stem cells for regenerative medicine
    • Wu SM, Hochedlinger K. Harnessing the potential of induced pluripotent stem cells for regenerative medicine. Nat Cell Biol 2011;13:497-505.
    • (2011) Nat Cell Biol , vol.13 , pp. 497-505
    • Wu, S.M.1    Hochedlinger, K.2
  • 84
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • Gore A, Li Z, Fung HL, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 2011;471:63-7.
    • (2011) Nature , vol.471 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.L.3
  • 85
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009;4:472-6.
    • (2009) Cell Stem Cell , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 86
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
    • Anokye-Danso F, Trivedi CM, Juhr D, et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 2011;8:376-88.
    • (2011) Cell Stem Cell , vol.8 , pp. 376-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Juhr, D.3
  • 87
    • 79955634826 scopus 로고    scopus 로고
    • A more efficient method to generate integration-free human iPS cells
    • Okita K, Matsumura Y, Sato Y, et al. A more efficient method to generate integration-free human iPS cells. Nat Methods 2011;8:409-12.
    • (2011) Nat Methods , vol.8 , pp. 409-412
    • Okita, K.1    Matsumura, Y.2    Sato, Y.3
  • 88
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida YS, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011;471:68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3
  • 89
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010;142:375-86.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3
  • 90
    • 84863629484 scopus 로고    scopus 로고
    • In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
    • Qian L, Huang Y, Spencer CI, et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012;485:593-8.
    • (2012) Nature , vol.485 , pp. 593-598
    • Qian, L.1    Huang, Y.2    Spencer, C.I.3
  • 91
    • 84863626782 scopus 로고    scopus 로고
    • Heart repair by reprogramming non-myocytes with cardiac transcription factors
    • Song K, Nam YJ, Luo X, et al. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 2012;485:599-604.
    • (2012) Nature , vol.485 , pp. 599-604
    • Song, K.1    Nam, Y.J.2    Luo, X.3
  • 92
    • 85027957068 scopus 로고    scopus 로고
    • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5
    • Chen JX, Krane M, Deutsch MA, et al. Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ Res 2012;111:50-5.
    • (2012) Circ Res , vol.111 , pp. 50-55
    • Chen, J.X.1    Krane, M.2    Deutsch, M.A.3
  • 93
    • 84861642380 scopus 로고    scopus 로고
    • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes
    • Jayawardena TM, Egemnazarov B, Finch EA, et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res 2012;110:1465-73.
    • (2012) Circ Res , vol.110 , pp. 1465-1473
    • Jayawardena, T.M.1    Egemnazarov, B.2    Finch, E.A.3
  • 94
    • 84875848994 scopus 로고    scopus 로고
    • Reprogramming of human fibroblasts toward a cardiac fate.
    • Nam YJ, Song K, Luo X, et al. Reprogramming of human fibroblasts toward a cardiac fate. Proc Natl Acad Sci U S A 2013;110:5588-93.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 5588-5593
    • Nam, Y.J.1    Song, K.2    Luo, X.3
  • 95
    • 84877794737 scopus 로고    scopus 로고
    • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes
    • Zhang D, Shadrin IY, Lam J, et al. Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials 2013;34:5813-20.
    • (2013) Biomaterials , vol.34 , pp. 5813-5820
    • Zhang, D.1    Shadrin, I.Y.2    Lam, J.3
  • 96
    • 84884819111 scopus 로고    scopus 로고
    • Trends in cardiovascular engineering: organizing the human heart
    • Tulloch NL, Murry CE. Trends in cardiovascular engineering: organizing the human heart. Trends Cardiovasc Med 2013;23:282-6.
    • (2013) Trends Cardiovasc Med , vol.23 , pp. 282-286
    • Tulloch, N.L.1    Murry, C.E.2
  • 97
    • 0037040160 scopus 로고    scopus 로고
    • Tissue engineering of a differentiated cardiac muscle construct
    • Zimmermann WH, Schneiderbanger K, Schubert P, et al. Tissue engineering of a differentiated cardiac muscle construct. Circ Res 2002;90:223-30.
    • (2002) Circ Res , vol.90 , pp. 223-230
    • Zimmermann, W.H.1    Schneiderbanger, K.2    Schubert, P.3
  • 98
    • 11144248959 scopus 로고    scopus 로고
    • Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds.
    • Radisic M, Park H, Shing H, et al. Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc Natl Acad Sci U S A 2004;101:18129-34.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 18129-18134
    • Radisic, M.1    Park, H.2    Shing, H.3
  • 99
    • 33645737594 scopus 로고    scopus 로고
    • Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts
    • Zimmermann WH, Melnychenko I, Wasmeier G, et al. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med 2006;12:452-8.
    • (2006) Nat Med , vol.12 , pp. 452-458
    • Zimmermann, W.H.1    Melnychenko, I.2    Wasmeier, G.3
  • 101
    • 79952065525 scopus 로고    scopus 로고
    • Transient regenerative potential of the neonatal mouse heart
    • Porrello ER, Mahmoud AI, Simpson E, et al. Transient regenerative potential of the neonatal mouse heart. Science 2011;331:1078-80.
    • (2011) Science , vol.331 , pp. 1078-1080
    • Porrello, E.R.1    Mahmoud, A.I.2    Simpson, E.3
  • 102
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann O, Bhardwaj RD, Bernard S, et al. Evidence for cardiomyocyte renewal in humans. Science 2009;324:98-102.
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1    Bhardwaj, R.D.2    Bernard, S.3
  • 103
    • 84872611623 scopus 로고    scopus 로고
    • Mammalian heart renewal by pre-existing cardiomyocytes
    • Senyo SE, Steinhauser ML, Pizzimenti CL, et al. Mammalian heart renewal by pre-existing cardiomyocytes. Nature 2013;493:433-6.
    • (2013) Nature , vol.493 , pp. 433-436
    • Senyo, S.E.1    Steinhauser, M.L.2    Pizzimenti, C.L.3
  • 104
    • 18844383961 scopus 로고    scopus 로고
    • p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
    • Engel FB, Schebesta M, Duong MT, et al. p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev 2005;19:1175-87.
    • (2005) Genes Dev , vol.19 , pp. 1175-1187
    • Engel, F.B.1    Schebesta, M.2    Duong, M.T.3
  • 105
    • 67650569135 scopus 로고    scopus 로고
    • Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
    • Bersell K, Arab S, Haring B, et al. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell 2009;138:257-70.
    • (2009) Cell , vol.138 , pp. 257-270
    • Bersell, K.1    Arab, S.2    Haring, B.3
  • 106
    • 34547691243 scopus 로고    scopus 로고
    • Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
    • Kühn B, del Monte F, Hajjar RJ, et al. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med 2007;13:962-9.
    • (2007) Nat Med , vol.13 , pp. 962-969
    • Kühn, B.1    del Monte, F.2    Hajjar, R.J.3
  • 107
    • 84880839534 scopus 로고    scopus 로고
    • Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair
    • Xin M, Olson EN, Bassel-Duby R. Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair. Nat Rev Mol Cell Biol 2013;14:529-41.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 529-541
    • Xin, M.1    Olson, E.N.2    Bassel-Duby, R.3
  • 108
    • 84871442001 scopus 로고    scopus 로고
    • Functional screening identifies miRNAs inducing cardiac regeneration
    • Eulalio A, Mano M, Dal Ferro M, et al. Functional screening identifies miRNAs inducing cardiac regeneration. Nature 2012;492:376-81.
    • (2012) Nature , vol.492 , pp. 376-381
    • Eulalio, A.1    Mano, M.2    Dal Ferro, M.3
  • 109
    • 33845708407 scopus 로고    scopus 로고
    • Re-programming of newt cardiomyocytes is induced by tissue regeneration
    • Laube F, Heister M, Scholz C, et al. Re-programming of newt cardiomyocytes is induced by tissue regeneration. J Cell Sci 2006;119:4719-29.
    • (2006) J Cell Sci , vol.119 , pp. 4719-4729
    • Laube, F.1    Heister, M.2    Scholz, C.3
  • 110
    • 77950200829 scopus 로고    scopus 로고
    • Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
    • Jopling C, Sleep E, Raya M, et al. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 2010;464:606-9.
    • (2010) Nature , vol.464 , pp. 606-609
    • Jopling, C.1    Sleep, E.2    Raya, M.3
  • 111
    • 77950201708 scopus 로고    scopus 로고
    • Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes
    • Kikuchi K, Holdway JE, Werdich AA, et al. Primary contribution to zebrafish heart regeneration by gata4(+) cardiomyocytes. Nature 2010;464:601-5.
    • (2010) Nature , vol.464 , pp. 601-605
    • Kikuchi, K.1    Holdway, J.E.2    Werdich, A.A.3
  • 112
    • 0142027772 scopus 로고    scopus 로고
    • Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction
    • Oh H, Bradfute SB, Gallardo TD, et al. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 2003;100:12313-8.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12313-12318
    • Oh, H.1    Bradfute, S.B.2    Gallardo, T.D.3
  • 113
    • 13544272476 scopus 로고    scopus 로고
    • Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages
    • Laugwitz KL, Moretti A, Lam J, et al. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature 2005;433:647-53.
    • (2005) Nature , vol.433 , pp. 647-653
    • Laugwitz, K.L.1    Moretti, A.2    Lam, J.3
  • 114
    • 0347623124 scopus 로고    scopus 로고
    • Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart
    • Martin CM, Meeson AP, Robertson SM, et al. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Dev Biol 2004;265:262-75.
    • (2004) Dev Biol , vol.265 , pp. 262-275
    • Martin, C.M.1    Meeson, A.P.2    Robertson, S.M.3
  • 115
    • 67349160766 scopus 로고    scopus 로고
    • Epicardial control of myocardial proliferation and morphogenesis
    • Sucov HM, Gu Y, Thomas S, et al. Epicardial control of myocardial proliferation and morphogenesis. Pediatr Cardiol 2009;30:617-25.
    • (2009) Pediatr Cardiol , vol.30 , pp. 617-625
    • Sucov, H.M.1    Gu, Y.2    Thomas, S.3
  • 116
    • 79955498411 scopus 로고    scopus 로고
    • Adult mouse epicardium modulates myocardial injury by secreting paracrine factors
    • Zhou B, Honor LB, He H, et al. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J Clin Invest 2011;121:1894-904.
    • (2011) J Clin Invest , vol.121 , pp. 1894-1904
    • Zhou, B.1    Honor, L.B.2    He, H.3
  • 117
    • 33846243239 scopus 로고    scopus 로고
    • Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization
    • Smart N, Risebro CA, Melville AA, et al. Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature 2007;445:177-82.
    • (2007) Nature , vol.445 , pp. 177-182
    • Smart, N.1    Risebro, C.A.2    Melville, A.A.3
  • 118
    • 79959819263 scopus 로고    scopus 로고
    • De novo cardiomyocytes from within the activated adult heart after injury
    • Smart N, Bollini S, Dube KN, et al. De novo cardiomyocytes from within the activated adult heart after injury. Nature 2011;474:640-4.
    • (2011) Nature , vol.474 , pp. 640-644
    • Smart, N.1    Bollini, S.2    Dube, K.N.3
  • 119
    • 84055214880 scopus 로고    scopus 로고
    • Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes
    • Zhou B, Honor LB, Ma Q, et al. Thymosin beta 4 treatment after myocardial infarction does not reprogram epicardial cells into cardiomyocytes. J Mol Cell Cardiol 2012;52:43-7.
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 43-47
    • Zhou, B.1    Honor, L.B.2    Ma, Q.3


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