Regenerating cardiac cells: Insights from the bench and the clinic

Cell and Tissue Research

Volumn 350, Issue 2, 2012, Pages 189-197

  Teng, Miao ^a   Zhao, XiaoHui ^a   Huang, YueSheng ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac; Cardiomyoctyes; Human; Progenitor cells; Regeneration; Stem cells

Indexed keywords

ADULT STEM CELL; CARDIAC STEM CELL; CELL REGENERATION; CELL TYPE; CORONARY ARTERY DISEASE; HEART DISEASE; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE INJURY; HUMAN; MAMMAL; NONHUMAN; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; STEM CELL; TISSUE REPAIR;

ANIMALS; HEART FAILURE; HUMANS; MICE; MYOCYTES, CARDIAC; REGENERATIVE MEDICINE; STEM CELLS;

MAMMALIA;

EID: 84871209770     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-012-1484-7     Document Type: Review

References (61)

1. Ahmadian Kia N, Bahrami AR et al (2010) Comparative analysis of chemokine receptor's expression in mesenchymal stem cells derived from human bone marrow and adipose tissue. J Mol Neurosci 44:178-185
2. Asahara T, Murohara T et al (1997) Isolation of putative progenitor endothelial cells for angiogenesis. Science 275:964-967
3. Assmus B, Schachinger V et al (2002) Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 106:3009-3017
4. Assmus B, Honold J et al (2006) Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med 355:1222-1232
5. Bearzi C, Rota M et al (2007) Human cardiac stem cells. Proc Natl Acad Sci USA 104:14068-14073
6. Beltrami AP, Barlucchi L et al (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114:763-776
7. Blin G, Nury D et al (2010) A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates. J Clin Invest 120:1125-1139
8. Bolli R, Chugh AR et al (2011) Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 378:1847-1857
9. Buckingham M, Meilhac S et al (2005) Building the mammalian heart from two sources of myocardial cells. Nat Rev Genet 6:826-835
10. Cai CL, Liang X et al (2003) Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5:877-889
11. Caprioli A, Koyano-Nakagawa N et al (2011) Nkx2-5 represses Gata1 gene expression and modulates the cellular fate of cardiac progenitors during embryogenesis. Circulation 123:1633-1641
12. Chen HT, Lee MJ, Chen CH, Chuang SC, Chang LF, Ho ML, Hung SH, Fu YC, Wang YH, Wang HI, Wang GJ, Kang L, Chang JK (2011) Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures. J Cell Mol Med 16:582-593
13. Chimenti I, Smith RR et al (2010) Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res 106:971-980
14. Fazel S, Cimini M et al (2006) Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest 116:1865-1877
15. Ferreira-Martins J, Ogorek B et al (2012) Cardiomyogenesis in the developing heart is regulated by c-kit-positive cardiac stem cells. Circ Res 110:701-715
16. Franco D, Moreno N et al (2007) Non-resident stem cell populations in regenerative cardiac medicine. Cell Mol Life Sci 64:683-691
17. Hare JM, Traverse JH et al (2009) A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction. J Am Coll Cardiol 54:2277-2286
18. Hill JM, Zalos G et al (2003) Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 348:593-600
19. Hu Y, Davison F et al (2003) Endothelial replacement and angiogenesis in arteriosclerotic lesions of allografts are contributed by circulating progenitor cells. Circulation 108:3122-3127
20. Hu S, Liu S et al (2011) Isolated coronary artery bypass graft combined with bone marrow mononuclear cells delivered through a graft vessel for patients with previous myocardial infarction and chronic heart failure: a single-center, randomized, double-blind, placebo-controlled clinical trial. J Am Coll Cardiol 57:2409-2415
21. Ikegame Y, Yamashita K et al (2011) Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. Cytotherapy 13:675-685
22. Janssens S, Dubois C et al (2006) Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 367:113-121
23. Kang HJ, Kim HS et al (2004) Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial. Lancet 363:751-756
24. Kawase Y, Ladage D et al (2011) Rescuing the failing heart by targeted gene transfer. J Am Coll Cardiol 57:1169-1180
25. Kocher AA, Schuster MD et al (2001) Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 7:430-436
26. Koninckx R, Daniels A et al (2010) Mesenchymal stem cells or cardiac progenitors for cardiac repair? A comparative study. Cell Mol Life Sci 68:2141-2156
27. Kubo H, Jaleel N et al (2008) Increased cardiac myocyte progenitors in failing human hearts. Circulation 118:649-657
28. Laugwitz KL, Moretti A et al (2008) Islet1 cardiovascular progenitors: a single source for heart lineages? Development 135:193-205
29. Leri A (2009) Human cardiac stem cells: the heart of a truth. Circulation 120:2515-2518
30. Lunde K, Solheim S et al (2006) Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 355:1199-1209
31. Madonna R, De Caterina R (2009) Adipose tissue: a new source for cardiovascular repair. J Cardiovasc Med (Hagerstown) 11(2):71-80
32. Makkar RR, Smith RR et al (2012) Intracoronary cardiospherederived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 379:895-904
33. Martin-Puig S, Wang Z et al (2008) Lives of a heart cell: tracing the origins of cardiac progenitors. Cell Stem Cell 2:320-331
34. Meyer GP, Wollert KC et al (2006) Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 113:1287-1294
35. Moretti A, Caron L et al (2006) Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127:1151-1165
36. Murry CE, Soonpaa MH et al (2004) Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428:664-668
37. Oh H, Bradfute SB et al (2003) Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci USA 100:12313-12318
38. Orlic D, Kajstura J et al (2001) Bone marrow cells regenerate infarcted myocardium. Nature 410:701-705
39. Pittenger MF, Mackay AM et al (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147
40. Planat-Benard V, Menard C et al (2004) Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells. Circ Res 94:223-229
41. Rangappa S, Fen C et al (2003) Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes. Ann Thorac Surg 75:775-779
42. Rosenzweig A (2006) Cardiac cell therapy-mixed results from mixed cells. N Engl J Med 355:1274-1277
43. Sandstedt J, Jonsson M et al (2010) C-kit+ CD45-cells found in the adult human heart represent a population of endothelial progenitor cells. Basic Res Cardiol 105:545-556
44. Scarabelli TM, Gottlieb RA (2004) Functional and clinical repercussions of myocyte apoptosis in the multifaceted damage by ischemia/reperfusion injury: old and new concepts after 10 years of contributions. Cell Death Differ 11 (Suppl 2):S144-S152
45. Schachinger V, Assmus B et al (2004) Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI trial. J Am Coll Cardiol 44:1690-1699
46. Schachinger V, Erbs S et al (2006) Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 355:1210-1221
47. Smith RR, Barile L et al (2007) Regenerative potential of cardiospherederived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115:896-908
48. Stamm C, Westphal B et al (2003) Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 361:45-46
49. Strauer BE, Steinhoff G (2011) 10 years of intracoronary and intramyocardial bone marrow stem cell therapy of the heart: from the methodological origin to clinical practice. J Am Coll Cardiol 58:1095-1104
50. Struthers AD (2005) Pathophysiology of heart failure following myocardial infarction. Heart 91 (Suppl 2):ii14-ii16
51. Tallini YN, Greene KS et al (2009) c-kit expression identifies cardiovascular precursors in the neonatal heart. Proc Natl Acad Sci USA 106:1808-1813
52. Tang XL, Rokosh G et al (2010) Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 121:293-305
53. Tendera M, Wojakowski W et al (2009) Intracoronary infusion of bone marrow-derived selected CD34+ CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre myocardial regeneration by intracoronary infusion of selected population of stem cells in acute myocardial infarction (REGENT) trial. Eur Heart J 30:1313-1321
54. Toma C, Pittenger MF et al (2002) Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105:93-98
55. van Ramshorst J, Bax JJ et al (2009) Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial. JAMA 301:1997-2004
56. Vidal MA, Walker NJ, Napoli E, Borjesson DL (2011) Evaluation of senescence in mesenchymal stem cells isolated from equine bone marrow, adipose tissue, and umbilical cord tissue. Stem Cells Dev 21:273-83
57. Vieira NM, Brandalise V, Zucconi E, Secco M, Strauss BE, Zatz M (2010) Isolation, characterization, and differentiation potential of canine adipose-derived stem cells. Cell Transplant 19:279-289
58. Visconti RP, Ebihara Y et al (2006) An in vivo analysis of hematopoietic stem cell potential: hematopoietic origin of cardiac valve interstitial cells. Circ Res 98:690-696
59. Wollert KC, Meyer GP et al (2004) Intracoronary autologous bonemarrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 364:141-148
60. Wu SM, Fujiwara Yet al (2006) Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 127:1137-1150
61. Yao K, Huang R et al (2008) Administration of intracoronary bone marrow mononuclear cells on chronic myocardial infarction improves diastolic function. Heart 94:1147-1153