Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 32, 2012, Pages 13016-13021

  Islas, Jose Francisco ^a,b   Liu, Yu ^c   Weng, Kuo Chan ^a,b   Robertson, Matthew J ^b   Zhang, Shuxing ^c   Prejusa, Allan ^b   Harger, John ^c   Tikhomirova, Dariya ^b,c   Chopra, Mani ^c   Iyer, Dinakar ^d   Mercola, Mark ^e   Oshima, Robert G ^e   Willerson, James T ^b   Potaman, Vladimir N ^b   Schwartz, Robert J ^b,c  

^a UNIVERSITY OF TEXAS   (United States)

^b ST LUKE S EPISCOPAL HOSPITAL   (United States)

^c University of Houston   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e BURNHAM INSTITUTE   (United States)

Author keywords

Cardiogenesis; Fibroblast reprograming; Kinetic imaging; Protein transduction

Indexed keywords

CALCIUM ION; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 2; TRANSCRIPTION FACTOR MESP1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIVISION; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; HEART MUSCLE CELL; HUMAN; HUMAN CELL; LENTIVIRINAE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMERE; SKIN FIBROBLAST;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOTTING, WESTERN; CELL TRANSDIFFERENTIATION; FIBROBLASTS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKOUT TECHNIQUES; HUMANS; MICE; MYOBLASTS, CARDIAC; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEIN C-ETS-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN;

ASCIDIA; CIONA; LENTIVIRUS; MAMMALIA; MURINAE;

EID: 84864696029     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1120299109     Document Type: Article

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