Editorial: Granulocyte colony-stimulating factor in cardiac repair: Time for a reappraisal?

European Journal of Heart Failure

Volumn 12, Issue 10, 2010, Pages 1021-1023

  Janssens, Stefan P ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE HEART INFARCTION; ANGIOPLASTY; DRUG EFFICACY; EDITORIAL; HEART FAILURE; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE REMODELING; HUMAN; ISCHEMIC HEART DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVASCULARIZATION; SCINTIGRAPHY; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STEM CELL MOBILIZATION; TREATMENT OUTCOME; ACUTE DISEASE; DISEASE COURSE; ECHOGRAPHY; HEART STROKE VOLUME; NOTE; PATHOPHYSIOLOGY; STEM CELL;

ACUTE DISEASE; DISEASE PROGRESSION; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; MYOCARDIAL INFARCTION; STEM CELLS; STROKE VOLUME; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 77957243198     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfq153     Document Type: Editorial

References (15)

1. Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Kober L, Maggioni AP, Solomon SD, Swedberg K, Van de Werf F, White H, Leimberger JD, Henis M, Edwards S, Zelenkofske S, Sellers MA, Califf RM. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 2003;349:1893-1906.
2. Leone AM, Rutella S, Bonanno G, Abbate A, Rebuzzi AG, Giovannini S, Lombardi M, Galiuto L, Liuzzo G, Andreotti F, Lanza GA, Contemi AM, Leone G, Crea F. Mobilization of bone marrow-derived stem cells after myocar-dial infarction and left ventricular function. Eur Heart J 2005;26:1196-1204.
3. Leone AM, Rutella S, Bonanno G, Contemi AM, de Ritis DG, Giannico MB, Rebuzzi AG, Leone G, Crea F. Endogenous G-CSF and CD34+ cell mobilization after acute myocardial infarction. Int J Cardiol 2006;111:202-208.
4. Wojakowski W, Tendera M, Michalowska A, Majka M, Kucia M, Maslankiewicz K, Wyderka R, Ochala A, Ratajczak MZ. Mobilization of CD34/CXCR4+, CD34/CD117+, c-met+ stem cells, and mononuclear cells expressing early cardiac, muscle, and endothelial markers into peripheral blood in patients with acute myo-cardial infarction. Circulation 2004;110:3213-3220.
5. Zohlnhofer D, Ott I, Mehilli J, Schomig K, Michalk F, Ibrahim T, Meisetschlager G, von Wedel J, Bollwein H, Seyfarth M, Dirschinger J, Schmitt C, Schwaiger M, Kastrati A, Schomig A. Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: a randomized controlled trial. JAMA 2006;295:1003-1010.
6. Engelmann MG, Theiss HD, Hennig-Theiss C, Huber A, Wintersperger BJ, Werle-Ruedinger AE, Schoenberg SO, Steinbeck G, Franz WM. Autologous bone marrow stem cell mobilization induced by granulocyte colony-stimulating factor after subacute ST-segment elevation myocardial infarction undergoing late revascularization: final results from the G-CSF-STEMI (Granulocyte Colony-Stimulating Factor ST-Segment Elevation Myocardial Infarction) trial. J Am Coll Cardiol 2006;48:1712-1721.
7. Schmitz N, Dreger P, Suttorp M, Rohwedder EB, Haferlach T, Loffler H, Hunter A, Russell NH. Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor). Blood 1995;85:1666-1672.
8. Ohtsuka M, Takano H, Zou Y, Toko H, Akazawa H, Qin Y, Suzuki M, Hasegawa H, Nakaya H, Komuro I. Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. FASEB J 2004; 18:851-853.
9. Ohki Y, Heissig B, Sato Y, Akiyama H, Zhu Z, Hicklin DJ, Shimada K, Ogawa H, Daida H, Hattori K, Ohsaka A. Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutro-phils. FASEB J 2005;19:2005-2007.
10. Kuhlmann MT, Kirchhof P, Klocke R, Hasib L, Stypmann J, Fabritz L, Stelljes M, Tian W, Zwiener M, Mueller M, Kienast J, Breithardt G, Nikol S. G-CSF/SCF reduces inducible arrhythmias in the infarcted heart potentially via increased con-nexin43 expression and arteriogenesis. J Exp Med 2006;203:87-97.
11. Jorgensen E, Baldazzi F, Ripa RS, Friis T, Wang Y, Helqvist S, Kastrup J. Instent neointimal hyperplasia after percutaneous intervention for ST-elevation myocar-dial infarction and treatment with granulocyte-colony stimulating factor. Results from the stem cells in myocardial infarction (STEMMI) trial. Int J Cardiol 2008; 139:269-275.
12. Abdel-Latif A, Bolli R, Zuba-Surma EK, Tleyjeh IM, Hornung CA, Dawn B. Gra-nulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials. Am Heart J 2008;156:216-226 e219.
13. Zohlnhofer D, Dibra A, Koppara T, de Waha A, Ripa RS, Kastrup J, Valgimigli M, Schomig A, Kastrati A. Stem cell mobilization by granulocyte colony-stimulating factor for myocardial recovery after acute myocardial infarction: a meta-analysis. J Am Coll Cardiol 2008;51: 1429-1437.
14. Achilli F, Malafronte C, Lenatti L, Gentile F, Dadone V, Gibelli G, Magglioni S, Squadroni L, DiLeo C, Burba I, Pesce M, Mircolio L, Capogrossi MC, Di Lelio A, Camisasca P, Morabito A, Colombo G, Pompilio G. Ganulocyte colony-stimulating factor attenuates left ventricular remodelling after acute anterior STEMI. Results of the single-blind, randomized, placebo-controlled multi-centre Stem Cell Mobilization in Acute Myocardial Infarction (STEM-AMI) trial. Eur J Heart Fail 2010;12:1112-1122.
15. Harada M, Qin Y, Takano H, Minamino T, Zou Y, Toko H, Ohtsuka M, Matsuura K, Sano M, Nishi J, Iwanaga K, Akazawa H, Kunieda T, Zhu W, Hasegawa H, Kunisada K, Nagai T, Nakaya H, Yamauchi-Takihara K, Komuro I. G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med 2005;11:305-311.