-
1
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee
-
American College of Chest Physicians/Society of Critical Care Medicine
-
Bone, R. C., R. A. Balk, F. B. Cerra, R. P. Dellinger, A. M. Fein, W. A. Knaus, R. M. Schein, and W. J. Sibbald. 1992. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101: 1644-1655.
-
(1992)
Chest
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
Knaus, W.A.6
Schein, R.M.7
Sibbald, W.J.8
-
2
-
-
34247338128
-
Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003
-
Dombrovskiy, V. Y., A. A. Martin, J. Sunderram, and H. L. Paz. 2007. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit. Care Med. 35: 1244-1250.
-
(2007)
Crit. Care Med.
, vol.35
, pp. 1244-1250
-
-
Dombrovskiy, V.Y.1
Martin, A.A.2
Sunderram, J.3
Paz, H.L.4
-
3
-
-
40049105092
-
Septic shock-vasopressin, norepinephrine, and urgency
-
Parrillo, J. E. 2008. Septic shock-vasopressin, norepinephrine, and urgency. N. Engl. J. Med. 358: 954-956.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 954-956
-
-
Parrillo, J.E.1
-
4
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus, D. C., W. T. Linde-Zwirble, J. Lidicker, G. Clermont, J. Carcillo, and M. R. Pinsky. 2001. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit. Care Med. 29: 1303-1310.
-
(2001)
Crit. Care Med.
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
Clermont, G.4
Carcillo, J.5
Pinsky, M.R.6
-
5
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov, R. 2007. Recognition of microorganisms and activation of the immune response. Nature 449: 819-826.
-
(2007)
Nature
, vol.449
, pp. 819-826
-
-
Medzhitov, R.1
-
6
-
-
34548849117
-
The role of complement in inflammatory diseases from behind the scenes into the spotlight
-
Markiewski, M. M., and J. D. Lambris. 2007. The role of complement in inflammatory diseases from behind the scenes into the spotlight. Am. J. Pathol. 171: 715-727.
-
(2007)
Am. J. Pathol.
, vol.171
, pp. 715-727
-
-
Markiewski, M.M.1
Lambris, J.D.2
-
7
-
-
77955883153
-
Complement: A key system for immune surveillance and homeostasis
-
Ricklin, D., G. Hajishengallis, K. Yang, and J. D. Lambris. 2010. Complement: a key system for immune surveillance and homeostasis. Nat. Immunol. 11: 785-797.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 785-797
-
-
Ricklin, D.1
Hajishengallis, G.2
Yang, K.3
Lambris, J.D.4
-
8
-
-
0034307339
-
The Toll receptor family and microbial recognition
-
Medzhitov, R., and C. Janeway, Jr. 2000. The Toll receptor family and microbial recognition. Trends Microbiol. 8: 452-456.
-
(2000)
Trends Microbiol.
, vol.8
, pp. 452-456
-
-
Medzhitov, R.1
Janeway Jr., C.2
-
9
-
-
62649121369
-
Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis
-
Alves-Filho, J. C., A. Freitas, F. O. Souto, F. Spiller, H. Paula-Neto, J. S. Silva, R. T. Gazzinelli, M. M. Teixeira, S. H. Ferreira, and F. Q. Cunha. 2009. Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis. Proc. Natl. Acad. Sci. USA 106: 4018-4023.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4018-4023
-
-
Alves-Filho, J.C.1
Freitas, A.2
Souto, F.O.3
Spiller, F.4
Paula-Neto, H.5
Silva, J.S.6
Gazzinelli, R.T.7
Teixeira, M.M.8
Ferreira, S.H.9
Cunha, F.Q.10
-
10
-
-
77951620500
-
Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis
-
Zou, L., Y. Feng, Y. J. Chen, R. Si, S. Shen, Q. Zhou, F. Ichinose, M. Scherrer-Crosbie, and W. Chao. 2010. Toll-like receptor 2 plays a critical role in cardiac dysfunction during polymicrobial sepsis. Crit. Care Med. 38: 1335-1342.
-
(2010)
Crit. Care Med.
, vol.38
, pp. 1335-1342
-
-
Zou, L.1
Feng, Y.2
Chen, Y.J.3
Si, R.4
Shen, S.5
Zhou, Q.6
Ichinose, F.7
Scherrer-Crosbie, M.8
Chao, W.9
-
11
-
-
58149149839
-
TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events
-
Cavassani, K. A., M. Ishii, H. Wen, M. A. Schaller, P. M. Lincoln, N. W. Lukacs, C. M. Hogaboam, and S. L. Kunkel. 2008. TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J. Exp. Med. 205: 2609-2621.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2609-2621
-
-
Cavassani, K.A.1
Ishii, M.2
Wen, H.3
Schaller, M.A.4
Lincoln, P.M.5
Lukacs, N.W.6
Hogaboam, C.M.7
Kunkel, S.L.8
-
12
-
-
31344481400
-
Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis
-
Alves-Filho, J. C., A. de Freitas, M. Russo, and F. Q. Cunha. 2006. Toll-like receptor 4 signaling leads to neutrophil migration impairment in polymicrobial sepsis. Crit. Care Med. 34: 461-470.
-
(2006)
Crit. Care Med.
, vol.34
, pp. 461-470
-
-
Alves-Filho, J.C.1
De Freitas, A.2
Russo, M.3
Cunha, F.Q.4
-
13
-
-
60549101332
-
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4
-
Roger, T., C. Froidevaux, D. Le Roy, M. K. Reymond, A. L. Chanson, D. Mauri, K. Burns, B. M. Riederer, S. Akira, and T. Calandra. 2009. Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4. Proc. Natl. Acad. Sci. USA 106: 2348-2352.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2348-2352
-
-
Roger, T.1
Froidevaux, C.2
Le Roy, D.3
Reymond, M.K.4
Chanson, A.L.5
Mauri, D.6
Burns, K.7
Riederer, B.M.8
Akira, S.9
Calandra, T.10
-
14
-
-
45149129895
-
Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis
-
Plitas, G., B. M. Burt, H. M. Nguyen, Z. M. Bamboat, and R. P. DeMatteo. 2008. Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis. J. Exp. Med. 205: 1277-1283.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1277-1283
-
-
Plitas, G.1
Burt, B.M.2
Nguyen, H.M.3
Bamboat, Z.M.4
DeMatteo, R.P.5
-
15
-
-
12644280801
-
Abrogation of the alternative complement pathway by targeted deletion of murine factor B
-
Matsumoto, M., W. Fukuda, A. Circolo, J. Goellner, J. Strauss-Schoenberger, X. Wang, S. Fujita, T. Hidvegi, D. D. Chaplin, and H. R. Colten. 1997. Abrogation of the alternative complement pathway by targeted deletion of murine factor B. Proc. Natl. Acad. Sci. USA 94: 8720-8725.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8720-8725
-
-
Matsumoto, M.1
Fukuda, W.2
Circolo, A.3
Goellner, J.4
Strauss-Schoenberger, J.5
Wang, X.6
Fujita, S.7
Hidvegi, T.8
Chaplin, D.D.9
Colten, H.R.10
-
16
-
-
65249154058
-
Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart
-
Singh, M. V., A. Kapoun, L. Higgins, W. Kutschke, J. M. Thurman, R. Zhang, M. Singh, J. Yang, X. Guan, J. S. Lowe, et al. 2009. Ca2+/calmodulin- dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart. J. Clin. Invest. 119: 986-996.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 986-996
-
-
Singh, M.V.1
Kapoun, A.2
Higgins, L.3
Kutschke, W.4
Thurman, J.M.5
Zhang, R.6
Singh, M.7
Yang, J.8
Guan, X.9
Lowe, J.S.10
-
17
-
-
33645453861
-
Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury
-
Thurman, J. M., P. A. Royer, D. Ljubanovic, B. Dursun, A. M. Lenderink, C. L. Edelstein, and V. M. Holers. 2006. Treatment with an inhibitory monoclonal antibody to mouse factor B protects mice from induction of apoptosis and renal ischemia/reperfusion injury. J. Am. Soc. Nephrol. 17: 707-715.
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 707-715
-
-
Thurman, J.M.1
Royer, P.A.2
Ljubanovic, D.3
Dursun, B.4
Lenderink, A.M.5
Edelstein, C.L.6
Holers, V.M.7
-
18
-
-
34347400796
-
Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo
-
Zhang, X., Y. Kimura, C. Fang, L. Zhou, G. Sfyroera, J. D. Lambris, R. A. Wetsel, T. Miwa, and W. C. Song. 2007. Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood 110: 228-236.
-
(2007)
Blood
, vol.110
, pp. 228-236
-
-
Zhang, X.1
Kimura, Y.2
Fang, C.3
Zhou, L.4
Sfyroera, G.5
Lambris, J.D.6
Wetsel, R.A.7
Miwa, T.8
Song, W.C.9
-
19
-
-
70349260730
-
Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production
-
Fang, C., X. Zhang, T. Miwa, and W. C. Song. 2009. Complement promotes the development of inflammatory T-helper 17 cells through synergistic interaction with Toll-like receptor signaling and interleukin-6 production. Blood 114: 1005-1015.
-
(2009)
Blood
, vol.114
, pp. 1005-1015
-
-
Fang, C.1
Zhang, X.2
Miwa, T.3
Song, W.C.4
-
20
-
-
77955915400
-
Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms
-
Kaczorowski, D. J., A. Afrazi, M. J. Scott, J. H. Kwak, R. Gill, R. D. Edmonds, Y. Liu, J. Fan, and T. R. Billiar. 2010. Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms. J. Leukoc. Biol. 88: 609-618.
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 609-618
-
-
Kaczorowski, D.J.1
Afrazi, A.2
Scott, M.J.3
Kwak, J.H.4
Gill, R.5
Edmonds, R.D.6
Liu, Y.7
Fan, J.8
Billiar, T.R.9
-
21
-
-
77950187449
-
Crosstalk pathways between Toll-like receptors and the complement system
-
Hajishengallis, G., and J. D. Lambris. 2010. Crosstalk pathways between Toll-like receptors and the complement system. Trends Immunol. 31: 154-163.
-
(2010)
Trends Immunol.
, vol.31
, pp. 154-163
-
-
Hajishengallis, G.1
Lambris, J.D.2
-
22
-
-
66149084764
-
Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C
-
Goring, K., Y. Huang, C. Mowat, C. Leger, T. H. Lim, R. Zaheer, D. Mok, L. A. Tibbles, D. Zygun, and B. W. Winston. 2009. Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C. Am. J. Physiol. Cell Physiol. 296: C1140-C1150.
-
(2009)
Am. J. Physiol. Cell Physiol.
, vol.296
-
-
Goring, K.1
Huang, Y.2
Mowat, C.3
Leger, C.4
Lim, T.H.5
Zaheer, R.6
Mok, D.7
Tibbles, L.A.8
Zygun, D.9
Winston, B.W.10
-
23
-
-
77951080405
-
Complement activation in emergency department patients with severe sepsis
-
Younger, J. G., D. O. Bracho, H. M. Chung-Esaki, M. Lee, G. K. Rana, A. Sen, and A. E. Jones. 2010. Complement activation in emergency department patients with severe sepsis. Acad. Emerg. Med. 17: 353-359.
-
(2010)
Acad. Emerg. Med.
, vol.17
, pp. 353-359
-
-
Younger, J.G.1
Bracho, D.O.2
Chung-Esaki, H.M.3
Lee, M.4
Rana, G.K.5
Sen, A.6
Jones, A.E.7
-
24
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451.
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
25
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto, M., S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and S. Akira. 2003. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
26
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
27
-
-
80052396985
-
Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4
-
Li, Y., R. Si, Y. Feng, H. H. Chen, L. Zou, E. Wang, M. Zhang, H. S. Warren, D. E. Sosnovik, and W. Chao. 2011. Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4. J. Biol. Chem. 286: 31308-31319.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 31308-31319
-
-
Li, Y.1
Si, R.2
Feng, Y.3
Chen, H.H.4
Zou, L.5
Wang, E.6
Zhang, M.7
Warren, H.S.8
Sosnovik, D.E.9
Chao, W.10
-
28
-
-
80052966642
-
Nonhematopoietic toll-like receptor 2 contributes to neutrophil and cardiac function impairment during polymicrobial sepsis
-
Zou, L., Y. Feng, M. Zhang, Y. Li, and W. Chao. 2011. Nonhematopoietic toll-like receptor 2 contributes to neutrophil and cardiac function impairment during polymicrobial sepsis. Shock 36: 370-380.
-
(2011)
Shock
, vol.36
, pp. 370-380
-
-
Zou, L.1
Feng, Y.2
Zhang, M.3
Li, Y.4
Chao, W.5
-
29
-
-
61449154547
-
Immunodesign of experimental sepsis by cecal ligation and puncture
-
Rittirsch, D., M. S. Huber-Lang, M. A. Flierl, and P. A. Ward. 2009. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat. Protoc. 4: 31-36.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 31-36
-
-
Rittirsch, D.1
Huber-Lang, M.S.2
Flierl, M.A.3
Ward, P.A.4
-
30
-
-
5444270100
-
A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice
-
Thurman, J. M., D. M. Kraus, G. Girardi, D. Hourcade, H. J. Kang, P. A. Royer, L. M. Mitchell, P. C. Giclas, J. Salmon, G. Gilkeson, and V. M. Holers. 2005. A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice. Mol. Immunol. 42: 87-97.
-
(2005)
Mol. Immunol.
, vol.42
, pp. 87-97
-
-
Thurman, J.M.1
Kraus, D.M.2
Girardi, G.3
Hourcade, D.4
Kang, H.J.5
Royer, P.A.6
Mitchell, L.M.7
Giclas, P.C.8
Salmon, J.9
Gilkeson, G.10
Holers, V.M.11
-
31
-
-
34248676285
-
Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: A randomized placebo-controlled study in mice
-
Leinhase, I., M. Rozanski, D. Harhausen, J. M. Thurman, O. I. Schmidt, A. M. Hossini, M. E. Taha, D. Rittirsch, P. A. Ward, V. M. Holers, et al. 2007. Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice. J. Neuroinflammation 4: 13.
-
(2007)
J. Neuroinflammation
, vol.4
, pp. 13
-
-
Leinhase, I.1
Rozanski, M.2
Harhausen, D.3
Thurman, J.M.4
Schmidt, O.I.5
Hossini, A.M.6
Taha, M.E.7
Rittirsch, D.8
Ward, P.A.9
Holers, V.M.10
-
32
-
-
0032080799
-
Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor
-
Quigg, R. J., Y. Kozono, D. Berthiaume, A. Lim, D. J. Salant, A. Weinfeld, P. Griffin, E. Kremmer, and V. M. Holers. 1998. Blockade of antibody-induced glomerulonephritis with Crry-Ig, a soluble murine complement inhibitor. J. Immunol. 160: 4553-4560.
-
(1998)
J. Immunol.
, vol.160
, pp. 4553-4560
-
-
Quigg, R.J.1
Kozono, Y.2
Berthiaume, D.3
Lim, A.4
Salant, D.J.5
Weinfeld, A.6
Griffin, P.7
Kremmer, E.8
Holers, V.M.9
-
33
-
-
0031015026
-
Extrahepatic complement biosynthesis: Where, when and why?
-
Morgan, B. P., and P. Gasque. 1997. Extrahepatic complement biosynthesis: where, when and why? Clin. Exp. Immunol. 107: 1-7.
-
(1997)
Clin. Exp. Immunol.
, vol.107
, pp. 1-7
-
-
Morgan, B.P.1
Gasque, P.2
-
34
-
-
33644928993
-
Local extravascular pool of C3 is a determinant of postischemic acute renal failure
-
Farrar, C. A., W. Zhou, T. Lin, and S. H. Sacks. 2006. Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J. 20: 217-226.
-
(2006)
FASEB J.
, vol.20
, pp. 217-226
-
-
Farrar, C.A.1
Zhou, W.2
Lin, T.3
Sacks, S.H.4
-
35
-
-
77949541233
-
Novel aspects of complement in kidney injury
-
Vieyra, M. B., and P. S. Heeger. 2010. Novel aspects of complement in kidney injury. Kidney Int. 77: 495-499.
-
(2010)
Kidney Int.
, vol.77
, pp. 495-499
-
-
Vieyra, M.B.1
Heeger, P.S.2
-
36
-
-
0242494429
-
Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection
-
Verschoor, A., M. A. Brockman, M. Gadjeva, D. M. Knipe, and M. C. Carroll. 2003. Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection. J. Immunol. 171: 5363-5371.
-
(2003)
J. Immunol.
, vol.171
, pp. 5363-5371
-
-
Verschoor, A.1
Brockman, M.A.2
Gadjeva, M.3
Knipe, D.M.4
Carroll, M.C.5
-
37
-
-
0030004710
-
Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component
-
Lambris, J. D., Z. Lao, T. J. Oglesby, J. P. Atkinson, C. E. Hack, and J. D. Becherer. 1996. Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component. J. Immunol. 156: 4821-4832.
-
(1996)
J. Immunol.
, vol.156
, pp. 4821-4832
-
-
Lambris, J.D.1
Lao, Z.2
Oglesby, T.J.3
Atkinson, J.P.4
Hack, C.E.5
Becherer, J.D.6
-
38
-
-
23844521731
-
Acute renal failure in critically ill patients: A multinational, multicenter study
-
Uchino, S., J. A. Kellum, R. Bellomo, G. S. Doig, H. Morimatsu, S. Morgera, M. Schetz, I. Tan, C. Bouman, E. Macedo, et al. 2005. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294: 813-818.
-
(2005)
JAMA
, vol.294
, pp. 813-818
-
-
Uchino, S.1
Kellum, J.A.2
Bellomo, R.3
Doig, G.S.4
Morimatsu, H.5
Morgera, S.6
Schetz, M.7
Tan, I.8
Bouman, C.9
Macedo, E.10
-
39
-
-
70349705711
-
Animal models of sepsis and sepsis-induced kidney injury
-
Doi, K., A. Leelahavanichkul, P. S. Yuen, and R. A. Star. 2009. Animal models of sepsis and sepsis-induced kidney injury. J. Clin. Invest. 119: 2868-2878.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2868-2878
-
-
Doi, K.1
Leelahavanichkul, A.2
Yuen, P.S.3
Star, R.A.4
-
40
-
-
79957693494
-
Sepsis and acute kidney injury
-
Zarjou, A., and A. Agarwal. 2011. Sepsis and acute kidney injury. J. Am. Soc. Nephrol. 22: 999-1006.
-
(2011)
J. Am. Soc. Nephrol.
, vol.22
, pp. 999-1006
-
-
Zarjou, A.1
Agarwal, A.2
-
41
-
-
34948814501
-
Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region
-
Zhang, Z., B. D. Humphreys, and J. V. Bonventre. 2007. Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region. J. Am. Soc. Nephrol. 18: 2704-2714.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 2704-2714
-
-
Zhang, Z.1
Humphreys, B.D.2
Bonventre, J.V.3
-
42
-
-
68049135322
-
Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults
-
Siew, E. D., L. B.Ware, T. Gebretsadik, A. Shintani, K. G. Moons, N.Wickersham, F. Bossert, and T. A. Ikizler. 2009. Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J. Am. Soc. Nephrol. 20: 1823-1832.
-
(2009)
J. Am. Soc. Nephrol.
, vol.20
, pp. 1823-1832
-
-
Siew, E.D.1
Ware, L.B.2
Gebretsadik, T.3
Shintani, A.4
Moons, K.G.5
Wickersham, N.6
Bossert, F.7
Ikizler, T.A.8
-
43
-
-
79751536146
-
The Ngal reporter mouse detects the response of the kidney to injury in real time
-
Paragas, N., A. Qiu, Q. Zhang, B. Samstein, S. X. Deng, K. M. Schmidt-Ott, M. Viltard, W. Yu, C. S. Forster, G. Gong, et al. 2011. The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat. Med. 17: 216-222.
-
(2011)
Nat. Med.
, vol.17
, pp. 216-222
-
-
Paragas, N.1
Qiu, A.2
Zhang, Q.3
Samstein, B.4
Deng, S.X.5
Schmidt-Ott, K.M.6
Viltard, M.7
Yu, W.8
Forster, C.S.9
Gong, G.10
-
44
-
-
77952921602
-
Review: Neutrophil gelatinase-associated lipocalin: A troponin-like biomarker for human acute kidney injury
-
Devarajan, P. 2010. Review: neutrophil gelatinase-associated lipocalin: a troponin-like biomarker for human acute kidney injury. Nephrology (Carlton) 15: 419-428.
-
(2010)
Nephrology (Carlton)
, vol.15
, pp. 419-428
-
-
Devarajan, P.1
-
45
-
-
84875262757
-
The inflammatory response in sepsis
-
Bosmann, M., and P. A. Ward. 2013. The inflammatory response in sepsis. Trends Immunol. 34: 129-136.
-
(2013)
Trends Immunol.
, vol.34
, pp. 129-136
-
-
Bosmann, M.1
Ward, P.A.2
-
46
-
-
5944251623
-
Caspase inhibitors improve survival in sepsis: A critical role of the lymphocyte
-
Hotchkiss, R. S., K. C. Chang, P. E. Swanson, K. W. Tinsley, J. J. Hui, P. Klender, S. Xanthoudakis, S. Roy, C. Black, E. Grimm, et al. 2000. Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat. Immunol. 1: 496-501.
-
(2000)
Nat. Immunol.
, vol.1
, pp. 496-501
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Swanson, P.E.3
Tinsley, K.W.4
Hui, J.J.5
Klender, P.6
Xanthoudakis, S.7
Roy, S.8
Black, C.9
Grimm, E.10
-
47
-
-
79952712223
-
Mitochondrial reactive oxygen species drive proinflammatory cytokine production
-
Naik, E., and V. M. Dixit. 2011. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J. Exp. Med. 208: 417-420.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 417-420
-
-
Naik, E.1
Dixit, V.M.2
-
48
-
-
33749357803
-
Role of oxidative stress in experimental sepsis and multisystem organ dysfunction
-
Crimi, E., V. Sica, A. S. Slutsky, H. Zhang, S. Williams-Ignarro, L. J. Ignarro, and C. Napoli. 2006. Role of oxidative stress in experimental sepsis and multisystem organ dysfunction. Free Radic. Res. 40: 665-672.
-
(2006)
Free Radic. Res.
, vol.40
, pp. 665-672
-
-
Crimi, E.1
Sica, V.2
Slutsky, A.S.3
Zhang, H.4
Williams-Ignarro, S.5
Ignarro, L.J.6
Napoli, C.7
-
49
-
-
28944434990
-
Reactive oxygen species
-
Bayir, H. 2005. Reactive oxygen species. Crit. Care Med. 33: S498-S501.
-
(2005)
Crit. Care Med.
, vol.33
-
-
Bayir, H.1
-
50
-
-
24644487357
-
Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection
-
Atkinson, C., H. Song, B. Lu, F. Qiao, T. A. Burns, V. M. Holers, G. C. Tsokos, and S. Tomlinson. 2005. Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection. J. Clin. Invest. 115: 2444-2453.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2444-2453
-
-
Atkinson, C.1
Song, H.2
Lu, B.3
Qiao, F.4
Burns, T.A.5
Holers, V.M.6
Tsokos, G.C.7
Tomlinson, S.8
-
51
-
-
0037105549
-
Cutting edge: Myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection
-
Weighardt, H., S. Kaiser-Moore, R. M. Vabulas, C. J. Kirschning, H. Wagner, and B. Holzmann. 2002. Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection. J. Immunol. 169: 2823-2827.
-
(2002)
J. Immunol.
, vol.169
, pp. 2823-2827
-
-
Weighardt, H.1
Kaiser-Moore, S.2
Vabulas, R.M.3
Kirschning, C.J.4
Wagner, H.5
Holzmann, B.6
-
52
-
-
80052148652
-
MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis
-
Feng, Y., L. Zou, M. Zhang, Y. Li, C. Chen, and W. Chao. 2011. MyD88 and Trif signaling play distinct roles in cardiac dysfunction and mortality during endotoxin shock and polymicrobial sepsis. Anesthesiology 115: 555-567.
-
(2011)
Anesthesiology
, vol.115
, pp. 555-567
-
-
Feng, Y.1
Zou, L.2
Zhang, M.3
Li, Y.4
Chen, C.5
Chao, W.6
-
53
-
-
49549102252
-
The alternative complement pathway revisited
-
Harboe, M., and T. E. Mollnes. 2008. The alternative complement pathway revisited. J. Cell. Mol. Med. 12: 1074-1084.
-
(2008)
J. Cell. Mol. Med.
, vol.12
, pp. 1074-1084
-
-
Harboe, M.1
Mollnes, T.E.2
-
54
-
-
42049109282
-
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury
-
Sheerin, N. S., P. Risley, K. Abe, Z. Tang, W. Wong, T. Lin, and S. H. Sacks. 2008. Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J. 22: 1065-1072.
-
(2008)
FASEB J.
, vol.22
, pp. 1065-1072
-
-
Sheerin, N.S.1
Risley, P.2
Abe, K.3
Tang, Z.4
Wong, W.5
Lin, T.6
Sacks, S.H.7
-
55
-
-
84862589661
-
Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis
-
Schepp-Berglind, J., C. Atkinson, M. Elvington, F. Qiao, P. Mannon, and S. Tomlinson. 2012. Complement-dependent injury and protection in a murine model of acute dextran sulfate sodium-induced colitis. J. Immunol. 188: 6309-6318.
-
(2012)
J. Immunol.
, vol.188
, pp. 6309-6318
-
-
Schepp-Berglind, J.1
Atkinson, C.2
Elvington, M.3
Qiao, F.4
Mannon, P.5
Tomlinson, S.6
-
56
-
-
4544235126
-
Involvement of the lectin pathway of complement activation in antimicrobial immune defense during experimental septic peritonitis
-
Windbichler, M., B. Echtenacher, T. Hehlgans, J. C. Jensenius, W. Schwaeble, and D. N. Mannel. 2004. Involvement of the lectin pathway of complement activation in antimicrobial immune defense during experimental septic peritonitis. Infect. Immun. 72: 5247-5252.
-
(2004)
Infect. Immun.
, vol.72
, pp. 5247-5252
-
-
Windbichler, M.1
Echtenacher, B.2
Hehlgans, T.3
Jensenius, J.C.4
Schwaeble, W.5
Mannel, D.N.6
-
57
-
-
1142310879
-
The dark side of C5a in sepsis
-
Ward, P. A. 2004. The dark side of C5a in sepsis. Nat. Rev. Immunol. 4: 133-142.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 133-142
-
-
Ward, P.A.1
-
58
-
-
0033052453
-
Protective effects of C5a blockade in sepsis
-
Czermak, B. J., V. Sarma, C. L. Pierson, R. L. Warner, M. Huber-Lang, N. M. Bless, H. Schmal, H. P. Friedl, and P. A. Ward. 1999. Protective effects of C5a blockade in sepsis. Nat. Med. 5: 788-792.
-
(1999)
Nat. Med.
, vol.5
, pp. 788-792
-
-
Czermak, B.J.1
Sarma, V.2
Pierson, C.L.3
Warner, R.L.4
Huber-Lang, M.5
Bless, N.M.6
Schmal, H.7
Friedl, H.P.8
Ward, P.A.9
-
59
-
-
0035863922
-
Role of C5a in multiorgan failure during sepsis
-
Huber-Lang, M., V. J. Sarma, K. T. Lu, S. R. McGuire, V. A. Padgaonkar, R. F. Guo, E. M. Younkin, R. G. Kunkel, J. Ding, R. Erickson, et al. 2001. Role of C5a in multiorgan failure during sepsis. J. Immunol. 166: 1193-1199.
-
(2001)
J. Immunol.
, vol.166
, pp. 1193-1199
-
-
Huber-Lang, M.1
Sarma, V.J.2
Lu, K.T.3
McGuire, S.R.4
Padgaonkar, V.A.5
Guo, R.F.6
Younkin, E.M.7
Kunkel, R.G.8
Ding, J.9
Erickson, R.10
-
60
-
-
79952743025
-
Distinct different contributions of the alternative and classical complement activation pathway for the innate host response during sepsis
-
Dahlke, K., C. D. Wrann, O. Sommerfeld, M. Sossdorf, P. Recknagel, S. Sachse, S. W. Winter, A. Klos, G. L. Stahl, Y. X. Ma, et al. 2011. Distinct different contributions of the alternative and classical complement activation pathway for the innate host response during sepsis. J. Immunol. 186: 3066-3075.
-
(2011)
J. Immunol.
, vol.186
, pp. 3066-3075
-
-
Dahlke, K.1
Wrann, C.D.2
Sommerfeld, O.3
Sossdorf, M.4
Recknagel, P.5
Sachse, S.6
Winter, S.W.7
Klos, A.8
Stahl, G.L.9
Ma, Y.X.10
-
61
-
-
0035807813
-
Complement activation in factor D-deficient mice
-
Xu, Y.,M. Ma, G. C. Ippolito, H.W. Schroeder, Jr.,M. C. Carroll, and J. E. Volanakis. 2001. Complement activation in factor D-deficient mice. Proc. Natl. Acad. Sci. USA 98: 14577-14582.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14577-14582
-
-
Xu, Y.1
Ma, M.2
Ippolito, G.C.3
Schroeder Jr., H.W.4
Carroll, M.C.5
Volanakis, J.E.6
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