Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome

Journal of Biological Chemistry

Volumn 288, Issue 47, 2013, Pages 33722-33737

  Ngadjeua, Flora ^a,b   Chiaravalli, Jeanne ^a   Traincard, François ^a   Raynal, Bertrand ^a   Fontan, Elisabeth ^a   Agou, Fabrice ^a  

^a CNRS   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; BINDING PROPERTIES; C-TERMINAL DOMAINS; IMMUNODEFICIENCY SYNDROMES; PATHOGENIC MUTATION; POINT MUTATIONS; SEDIMENTATION VELOCITIES; STRUCTURAL MODELING;

BINDING ENERGY; CELL CULTURE; CHAINS; DEFECTS;

ZINC;

I KAPPA B KINASE; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ZINC FINGER PROTEIN;

AMINO ACID SEQUENCE; ANHIDROTIC ECTODERMAL DYSPLASIA WITH IMMUNODEFICIENCY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; HYPOHIDROTIC ECTODERMAL DYSPLASIA; IMMUNE DEFICIENCY; IN VIVO STUDY; LEUKEMIA CELL LINE; MOLECULAR MODEL; MUTAGENESIS; PATHOGENESIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UBIQUITINATION;

EDA-ID; FLUORESCENCE; IKK COMPLEX; IMMUNODEFICIENCY; NEMO; NF-ΚB; UBIQUITIN; ZINC FINGER;

AMINO ACID SUBSTITUTION; ANIMALS; ECTODERMAL DYSPLASIA; HUMANS; I-KAPPA B KINASE; IMMUNOLOGIC DEFICIENCY SYNDROMES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MICE; MICE, MUTANT STRAINS; MODELS, MOLECULAR; MUTATION, MISSENSE; NF-KAPPA B; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; UBIQUITIN; ZINC FINGERS;

EID: 84888349683     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.483305     Document Type: Article

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