-
1
-
-
0034719680
-
The transcription factor NF-κB: Control of oncogenesis and cancer therapy resistance
-
Mayo, M. W., and A. S. Baldwin. 2000. The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance. Biochim. Biophys. Acto 1470:M55.
-
(2000)
Biochim. Biophys. Acto
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
2
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
Locksley, R. M., N. Killeen, and M. J. Lenardo. 2001. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104:487.
-
(2001)
Cell
, vol.104
, pp. 487
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
3
-
-
0031897632
-
NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh, S., M. May, and E. Kopp. 1998. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:225.
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 225
-
-
Ghosh, S.1
May, M.2
Kopp, E.3
-
4
-
-
0036234459
-
Missing pieces in the NF-κB puzzle
-
Ghosh, S., and K. Karin. 2002. Missing pieces in the NF-κB puzzle. Cell 109:S81.
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, K.2
-
5
-
-
0034661272
-
Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: Additional defect in neurulation
-
Li, Q., G. Estepa, S. Memet, A. Israel, and I. M. Verma. 2000. Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. Genes Dev. 14:1729.
-
(2000)
Genes Dev.
, vol.14
, pp. 1729
-
-
Li, Q.1
Estepa, G.2
Memet, S.3
Israel, A.4
Verma, I.M.5
-
6
-
-
0033563227
-
IKK1-deficient mice exhibit abnormal development of skin and skeleton
-
Li, Q., Q. Lu, J. Y. Hwang, D. Buscher, K.-F. Lee, J. C. Izpisua-Belmonte, and I. M. Verma. 1999. IKK1-deficient mice exhibit abnormal development of skin and skeleton. Genes Dev. 13:1322.
-
(1999)
Genes Dev.
, vol.13
, pp. 1322
-
-
Li, Q.1
Lu, Q.2
Hwang, J.Y.3
Buscher, D.4
Lee, K.-F.5
Izpisua-Belmonte, J.C.6
Verma, I.M.7
-
7
-
-
0033537739
-
Severe liver degeneration in mice lacking the IκB kinase 2 gene
-
Li, Q., D. Van Antwerp, F. Mercurio, K.-F. Lee, and I. M. Verma. 1999. Severe liver degeneration in mice lacking the IκB kinase 2 gene. Science 284:321.
-
(1999)
Science
, vol.284
, pp. 321
-
-
Li, Q.1
Van Antwerp, D.2
Mercurio, F.3
Lee, K.-F.4
Verma, I.M.5
-
8
-
-
0033537757
-
Limb and skin abnormalities in mice lacking IKKα
-
Takeda, K., O. Takeuchi, T. Tsujimura, S. Itami, O. Adachi, T. Kawai, H. Sanjo, K. Yoshikawa, N. Terada, and S. Akira. 1999. Limb and skin abnormalities in mice lacking IKKα. Science 284:313.
-
(1999)
Science
, vol.284
, pp. 313
-
-
Takeda, K.1
Takeuchi, O.2
Tsujimura, T.3
Itami, S.4
Adachi, O.5
Kawai, T.6
Sanjo, H.7
Yoshikawa, K.8
Terada, N.9
Akira, S.10
-
9
-
-
0033537767
-
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase
-
Hu, Y., V. Baud, M. Delhase, P. Zhang, T. Deerinck, M. Ellisman, R. Johnson, and M. Karin. 1999. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKα subunit of IκB kinase. Science 284:316.
-
(1999)
Science
, vol.284
, pp. 316
-
-
Hu, Y.1
Baud, V.2
Delhase, M.3
Zhang, P.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
10
-
-
0037024696
-
Regulation of IκB kinase (IKK)γ/NEMO function by IKKβ-mediated phosphorylation
-
Prajapati, S., and R. B. Gaynor. 2002. Regulation of IκB kinase (IKK)γ/NEMO function by IKKβ-mediated phosphorylation. J. Biol. Chem. 277:24331.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 24331
-
-
Prajapati, S.1
Gaynor, R.B.2
-
11
-
-
0033712615
-
Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation
-
Zhang, S. Q., A. Kovalenko, G. Cantarella, and D. Wallach. 2000. Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKγ) upon receptor stimulation. Immunity 12:301.
-
(2000)
Immunity
, vol.12
, pp. 301
-
-
Zhang, S.Q.1
Kovalenko, A.2
Cantarella, G.3
Wallach, D.4
-
12
-
-
0035021123
-
The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
-
Devin, A., Y. Lin, S. Yamaoka, Z. Li, M. Karin, and Z. G. Liu. 2001. The α and β subunits of IκB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol. Cell. Biol. 21:3986.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3986
-
-
Devin, A.1
Lin, Y.2
Yamaoka, S.3
Li, Z.4
Karin, M.5
Liu, Z.G.6
-
13
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin, A., A. Cook, Y. Lin, Y. Rodriguez, M. Kelliher, and Z. G. Liu. 2000. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 12:419.
-
(2000)
Immunity
, vol.12
, pp. 419
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.G.6
-
14
-
-
0034713270
-
Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti
-
Smahi, A., G. Courtois, P. Vabres, S. Yamaoka, S. Heuertz, A. Munnich, A. Israel, N. S. Heiss, S. M. Klauck, P. Kioschis, et al. 2000. Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti. Nature 405:466.
-
(2000)
Nature
, vol.405
, pp. 466
-
-
Smahi, A.1
Courtois, G.2
Vabres, P.3
Yamaoka, S.4
Heuertz, S.5
Munnich, A.6
Israel, A.7
Heiss, N.S.8
Klauck, S.M.9
Kioschis, P.10
-
15
-
-
0035093630
-
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling
-
Doffinger, R., A. Smahi, C. Bessia, F. Geissmann, J. Feinberg, A. Durandy, C. Bodemer, S. Kenwrick, S. Dupuis-Girod, S. Blanche, et al. 2001. X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling. Nat. Genet. 27:277.
-
(2001)
Nat. Genet.
, vol.27
, pp. 277
-
-
Doffinger, R.1
Smahi, A.2
Bessia, C.3
Geissmann, F.4
Feinberg, J.5
Durandy, A.6
Bodemer, C.7
Kenwrick, S.8
Dupuis-Girod, S.9
Blanche, S.10
-
16
-
-
0035286726
-
Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia
-
Jain, A., C. A. Ma, S. Liu, M. Brown, J. Cohen, and W. Strober. 2001. Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia. Nat. Immun. 2:223.
-
(2001)
Nat. Immun.
, vol.2
, pp. 223
-
-
Jain, A.1
Ma, C.A.2
Liu, S.3
Brown, M.4
Cohen, J.5
Strober, W.6
-
17
-
-
0035825119
-
Wnt-1 signaling inhibits apoptosis by activating β-catenin/T cell factor-mediated transcription
-
Chen, S., D. C. Guttridge, Y. You, Z. Zhang, A. Fribley, M. W. Mayo, J. Kitajewski, and C.-Y. Wang. 2001. Wnt-1 signaling inhibits apoptosis by activating β-catenin/T cell factor-mediated transcription. J. Cell Biol. 152:87.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 87
-
-
Chen, S.1
Guttridge, D.C.2
You, Y.3
Zhang, Z.4
Fribley, A.5
Mayo, M.W.6
Kitajewski, J.7
Wang, C.-Y.8
-
18
-
-
0141621240
-
A role for NF-κB essential modifier/IκB kinase-γ (NEMO/IKKγ) ubiquitination in the activation of the IκB kinase complex by tumor necrosis factor-α
-
Tang, E., C.-Y. Wang, Y. Xiong, and K. Guan. 2003. A role for NF-κB essential modifier/IκB kinase-γ (NEMO/IKKγ) ubiquitination in the activation of the IκB kinase complex by tumor necrosis factor-α. J. Biol. Chem. 278:37297.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37297
-
-
Tang, E.1
Wang, C.-Y.2
Xiong, Y.3
Guan, K.4
-
19
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB
-
Madrid, L. V., C. Y. Wang, D. C. Guttridge, A. J. Schottelius, A. S. Baldwin, Jr., and M. W. Mayo. 2000. Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-κB. Mol. Cell. Biol. 20:1626.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1626
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin Jr., A.S.5
Mayo, M.W.6
-
20
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang, C.-Y., M. W. Mayo, and A. S. Baldwin. 1996. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 274:784.
-
(1996)
Science
, vol.274
, pp. 784
-
-
Wang, C.-Y.1
Mayo, M.W.2
Baldwin, A.S.3
-
21
-
-
0032508414
-
NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Wang, C.-Y., M. W. Mayo, R. C. Korneluk, D. V. Goeddel, and A. S. Baldwin. 1998. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281:1680.
-
(1998)
Science
, vol.281
, pp. 1680
-
-
Wang, C.-Y.1
Mayo, M.W.2
Korneluk, R.C.3
Goeddel, D.V.4
Baldwin, A.S.5
-
22
-
-
0035854749
-
Nuclear factor-κB-inducible death effector domain-containing protein suppresses tumor necrosis factor-mediated apoptosis by inhibiting caspase-8 activity
-
You, Z., H. Ouyang, D. Lopatin, P. J. Polverini, and C.-Y. Wang. 2001. Nuclear factor-κB-inducible death effector domain-containing protein suppresses tumor necrosis factor-mediated apoptosis by inhibiting caspase-8 activity. J. Biol. Chem. 276:26398.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26398
-
-
You, Z.1
Ouyang, H.2
Lopatin, D.3
Polverini, P.J.4
Wang, C.-Y.5
-
23
-
-
0036483890
-
Potentiation of tumor necrosis factor-mediated apoptosis of oral squamous cell carcinoma cells by adenovirus-mediated gene transfer of NF-κB inhibitor
-
Chen, S., A. Fribley, and C.-Y. Wang. 2001. Potentiation of tumor necrosis factor-mediated apoptosis of oral squamous cell carcinoma cells by adenovirus-mediated gene transfer of NF-κB inhibitor. J. Dent. Res. 81:98.
-
(2001)
J. Dent. Res.
, vol.81
, pp. 98
-
-
Chen, S.1
Fribley, A.2
Wang, C.-Y.3
-
24
-
-
0033514445
-
Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis
-
Li, Y., J. Kang, J. Friedman, L. Tarassishin, J. Ye, A. Kovalenko, D. Wallach, and M. S. Horwitz. 1999. Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis. Proc. Natl. Acad. Sci. USA 96:1042.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1042
-
-
Li, Y.1
Kang, J.2
Friedman, J.3
Tarassishin, L.4
Ye, J.5
Kovalenko, A.6
Wallach, D.7
Horwitz, M.S.8
-
25
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga, M. A., W. C. Yeh, I. Sarosi, G. S. Duncan, C. Furlonger, A. Ho, S. Morony, C. Capparelli, G. Van, S. Kaufman, et al. 1999. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1015.
-
(1999)
Genes Dev.
, vol.13
, pp. 1015
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
Duncan, G.S.4
Furlonger, C.5
Ho, A.6
Morony, S.7
Capparelli, C.8
Van, G.9
Kaufman, S.10
-
27
-
-
0037040981
-
Divergence of bacteria[lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1
-
Bannerman, D. D., J. C. Tupper, R. D. Erwert, R. K. Winn, and J. M. Harlan. 2002. Divergence of bacteria[lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1. J. Biol. Chem. 277:8048.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8048
-
-
Bannerman, D.D.1
Tupper, J.C.2
Erwert, R.D.3
Winn, R.K.4
Harlan, J.M.5
-
28
-
-
0036178063
-
Toll receptors: A central element in innate immune responses
-
Vasselon, T., and P. A. Detmers. 2002. Toll receptors: a central element in innate immune responses. Infect. Immun. 70:1033.
-
(2002)
Infect. Immun.
, vol.70
, pp. 1033
-
-
Vasselon, T.1
Detmers, P.A.2
-
29
-
-
0036721696
-
Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase
-
Hull, C., G. McLean, F. Wong, P. J. Duriez, and A. Karsan. 2002. Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase. Immunology 169:2611.
-
(2002)
Immunology
, vol.169
, pp. 2611
-
-
Hull, C.1
McLean, G.2
Wong, F.3
Duriez, P.J.4
Karsan, A.5
-
30
-
-
0034624810
-
Somatic mutagenesis studies of NF-κB signaling in human T cells: Evidence for an essential role of IKKγ in NF-κB activation by T-cell costimulatory signals and HTLV-1 Tax protein
-
Harhaj, E. W., L. Good, G. Xiao, M. Uhlik, M. E. Cvijic, I. Rivera-Walsh, and S. C. Sun. 2000. Somatic mutagenesis studies of NF-κB signaling in human T cells: evidence for an essential role of IKKγ in NF-κB activation by T-cell costimulatory signals and HTLV-1 Tax protein. Oncogene 19:1448.
-
(2000)
Oncogene
, vol.19
, pp. 1448
-
-
Harhaj, E.W.1
Good, L.2
Xiao, G.3
Uhlik, M.4
Cvijic, M.E.5
Rivera-Walsh, I.6
Sun, S.C.7
-
31
-
-
0033537719
-
Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation
-
Delhase, M., M. Hayakawa, Y. Chen, and M. Karin. 1999. Positive and negative regulation of IκB kinase activity through IKKβ subunit phosphorylation. Science 284:309.
-
(1999)
Science
, vol.284
, pp. 309
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
Karin, M.4
-
32
-
-
0036724051
-
The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation
-
Markris, C., J. L. Roberts, and M. Karin. 2002. The carboxyl-terminal region of IκB kinase γ (IKKγ) is required for full IKK activation. Mol. Cell. Biol. 22:6573.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6573
-
-
Markris, C.1
Roberts, J.L.2
Karin, M.3
|