메뉴 건너뛰기




Volumn 27, Issue 1, 2014, Pages 25-31

Structural insights into G protein-coupled receptor kinase function

Author keywords

[No Author keywords available]

Indexed keywords

BALANOL; G PROTEIN COUPLED RECEPTOR KINASE; PAROXETINE; RHODOPSIN; TUBULIN; G PROTEIN COUPLED RECEPTOR; PHOSPHOLIPID;

EID: 84888336227     PISSN: 09550674     EISSN: 18790410     Source Type: Journal    
DOI: 10.1016/j.ceb.2013.10.009     Document Type: Review
Times cited : (52)

References (39)
  • 1
    • 83555168220 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: more than just kinases and not only for GPCRs
    • Gurevich E.V., Tesmer J.J., Mushegian A., Gurevich V.V. G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Pharmacol Ther 2012, 133:40-69.
    • (2012) Pharmacol Ther , vol.133 , pp. 40-69
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 2
    • 84858611820 scopus 로고    scopus 로고
    • The origin and evolution of G protein-coupled receptor kinases
    • Mushegian A., Gurevich V.V., Gurevich E.V. The origin and evolution of G protein-coupled receptor kinases. PLoS One 2012, 7:e33806.
    • (2012) PLoS One , vol.7
    • Mushegian, A.1    Gurevich, V.V.2    Gurevich, E.V.3
  • 3
    • 46649109793 scopus 로고    scopus 로고
    • Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation
    • Singh P., Wang B., Maeda T., Palczewski K., Tesmer J.J. Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation. J Biol Chem 2008, 283:14053-14062.
    • (2008) J Biol Chem , vol.283 , pp. 14053-14062
    • Singh, P.1    Wang, B.2    Maeda, T.3    Palczewski, K.4    Tesmer, J.J.5
  • 4
    • 0037799206 scopus 로고    scopus 로고
    • Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gβγ
    • Lodowski D.T., Pitcher J.A., Capel W.D., Lefkowitz R.J., Tesmer J.J. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gβγ. Science 2003, 300:1256-1262.
    • (2003) Science , vol.300 , pp. 1256-1262
    • Lodowski, D.T.1    Pitcher, J.A.2    Capel, W.D.3    Lefkowitz, R.J.4    Tesmer, J.J.5
  • 6
    • 33745207354 scopus 로고    scopus 로고
    • The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs
    • Lodowski D.T., Tesmer V.M., Benovic J.L., Tesmer J.J. The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs. J Biol Chem 2006, 281:16785-16793.
    • (2006) J Biol Chem , vol.281 , pp. 16785-16793
    • Lodowski, D.T.1    Tesmer, V.M.2    Benovic, J.L.3    Tesmer, J.J.4
  • 7
    • 77957778459 scopus 로고    scopus 로고
    • Molecular basis for activation of G protein-coupled receptor kinases
    • Boguth C.A., Singh P., Huang C.C., Tesmer J.J. Molecular basis for activation of G protein-coupled receptor kinases. EMBO J 2010, 29:3249-3259.
    • (2010) EMBO J , vol.29 , pp. 3249-3259
    • Boguth, C.A.1    Singh, P.2    Huang, C.C.3    Tesmer, J.J.4
  • 8
    • 77957068247 scopus 로고    scopus 로고
    • Structure and function of regulator of G protein signaling homology domains
    • Tesmer J.J. Structure and function of regulator of G protein signaling homology domains. Prog Mol Biol Transl Sci 2009, 86:75-113.
    • (2009) Prog Mol Biol Transl Sci , vol.86 , pp. 75-113
    • Tesmer, J.J.1
  • 10
    • 66149178593 scopus 로고    scopus 로고
    • A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases
    • Huang C.C., Yoshino-Koh K., Tesmer J.J. A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases. J Biol Chem 2009, 284:17206-17215.
    • (2009) J Biol Chem , vol.284 , pp. 17206-17215
    • Huang, C.C.1    Yoshino-Koh, K.2    Tesmer, J.J.3
  • 11
    • 33846590132 scopus 로고    scopus 로고
    • The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module
    • Kannan N., Haste N., Taylor S.S., Neuwald A.F. The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proc Natl Acad Sci U S A 2007, 104:1272-1277.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1272-1277
    • Kannan, N.1    Haste, N.2    Taylor, S.S.3    Neuwald, A.F.4
  • 12
    • 19344363250 scopus 로고    scopus 로고
    • Pathophysiological roles of G protein-coupled receptor kinases
    • Metaye T., Gibelin H., Perdrisot R., Kraimps J.L. Pathophysiological roles of G protein-coupled receptor kinases. Cell Signal 2005, 17:917-928.
    • (2005) Cell Signal , vol.17 , pp. 917-928
    • Metaye, T.1    Gibelin, H.2    Perdrisot, R.3    Kraimps, J.L.4
  • 15
    • 77957229688 scopus 로고    scopus 로고
    • Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-κB-dependent hypertrophic gene expression
    • Sorriento D., Santulli G., Fusco A., Anastasio A., Trimarco B., Iaccarino G. Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-κB-dependent hypertrophic gene expression. Hypertension 2010, 56:696-704.
    • (2010) Hypertension , vol.56 , pp. 696-704
    • Sorriento, D.1    Santulli, G.2    Fusco, A.3    Anastasio, A.4    Trimarco, B.5    Iaccarino, G.6
  • 16
    • 84867033583 scopus 로고    scopus 로고
    • Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication
    • Gold J.I., Gao E., Shang X., Premont R.T., Koch W.J. Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication. Circ Res 2012, 111:1048-1053.
    • (2012) Circ Res , vol.111 , pp. 1048-1053
    • Gold, J.I.1    Gao, E.2    Shang, X.3    Premont, R.T.4    Koch, W.J.5
  • 17
    • 84874607739 scopus 로고    scopus 로고
    • Nuclear translocation of cardiac G protein-coupled receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process
    • Gold J.I., Martini J.S., Hullmann J., Gao E., Chuprun J.K., Lee L., Tilley D.G., Rabinowitz J.E., Bossuyt J., Bers D.M., et al. Nuclear translocation of cardiac G protein-coupled receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process. PLoS One 2013, 8:e57324.
    • (2013) PLoS One , vol.8
    • Gold, J.I.1    Martini, J.S.2    Hullmann, J.3    Gao, E.4    Chuprun, J.K.5    Lee, L.6    Tilley, D.G.7    Rabinowitz, J.E.8    Bossuyt, J.9    Bers, D.M.10
  • 19
    • 84860350915 scopus 로고    scopus 로고
    • AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
    • Raake P.W., Schlegel P., Ksienzyk J., Reinkober J., Barthelmes J., Schinkel S., Pleger S., Mier W., Haberkorn U., Koch W.J., et al. AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model. Eur Heart J 2013, 34:1437-1447.
    • (2013) Eur Heart J , vol.34 , pp. 1437-1447
    • Raake, P.W.1    Schlegel, P.2    Ksienzyk, J.3    Reinkober, J.4    Barthelmes, J.5    Schinkel, S.6    Pleger, S.7    Mier, W.8    Haberkorn, U.9    Koch, W.J.10
  • 21
    • 84864831457 scopus 로고    scopus 로고
    • Molecular mechanism for inhibition of G protein-coupled receptor kinase 2 by a selective RNA aptamer
    • Tesmer V.M., Lennarz S., Mayer G., Tesmer J.J. Molecular mechanism for inhibition of G protein-coupled receptor kinase 2 by a selective RNA aptamer. Structure 2012, 20:1300-1309.
    • (2012) Structure , vol.20 , pp. 1300-1309
    • Tesmer, V.M.1    Lennarz, S.2    Mayer, G.3    Tesmer, J.J.4
  • 22
    • 0024596301 scopus 로고
    • Inhibition of the β-adrenergic receptor kinase by polyanions
    • Benovic J.L., Stone W.C., Caron M.G., Lefkowitz R.J. Inhibition of the β-adrenergic receptor kinase by polyanions. J Biol Chem 1989, 264:6707-6710.
    • (1989) J Biol Chem , vol.264 , pp. 6707-6710
    • Benovic, J.L.1    Stone, W.C.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 23
    • 0024278380 scopus 로고
    • Rhodopsin kinase: substrate specificity and factors that influence activity
    • Palczewski K., McDowell J.H., Hargrave P.A. Rhodopsin kinase: substrate specificity and factors that influence activity. Biochemistry 1988, 27:2306-2313.
    • (1988) Biochemistry , vol.27 , pp. 2306-2313
    • Palczewski, K.1    McDowell, J.H.2    Hargrave, P.A.3
  • 24
    • 77649218358 scopus 로고    scopus 로고
    • Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol
    • Tesmer J.J., Tesmer V.M., Lodowski D.T., Steinhagen H., Huber J. Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol. J Med Chem 2010, 53:1867-1870.
    • (2010) J Med Chem , vol.53 , pp. 1867-1870
    • Tesmer, J.J.1    Tesmer, V.M.2    Lodowski, D.T.3    Steinhagen, H.4    Huber, J.5
  • 26
    • 79960223285 scopus 로고    scopus 로고
    • Molecular mechanism of selectivity among G protein-coupled receptor kinase 2 inhibitors
    • Thal D.M., Yeow R.Y., Schoenau C., Huber J., Tesmer J.J. Molecular mechanism of selectivity among G protein-coupled receptor kinase 2 inhibitors. Mol Pharmacol 2011, 80:294-303.
    • (2011) Mol Pharmacol , vol.80 , pp. 294-303
    • Thal, D.M.1    Yeow, R.Y.2    Schoenau, C.3    Huber, J.4    Tesmer, J.J.5
  • 27
    • 67649726156 scopus 로고    scopus 로고
    • Protein kinase inhibitors: contributions from structure to clinical compounds
    • Johnson L.N. Protein kinase inhibitors: contributions from structure to clinical compounds. Q Rev Biophys 2009, 42:1-40.
    • (2009) Q Rev Biophys , vol.42 , pp. 1-40
    • Johnson, L.N.1
  • 29
    • 0027469860 scopus 로고
    • Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin
    • Palczewski K., Buczylko J., Lebioda L., Crabb J.W., Polans A.S. Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin. J Biol Chem 1993, 268:6004-6013.
    • (1993) J Biol Chem , vol.268 , pp. 6004-6013
    • Palczewski, K.1    Buczylko, J.2    Lebioda, L.3    Crabb, J.W.4    Polans, A.S.5
  • 31
    • 68049097974 scopus 로고    scopus 로고
    • Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation
    • Pao C.S., Barker B.L., Benovic J.L. Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry 2009, 48:7325-7333.
    • (2009) Biochemistry , vol.48 , pp. 7325-7333
    • Pao, C.S.1    Barker, B.L.2    Benovic, J.L.3
  • 32
    • 79952796822 scopus 로고    scopus 로고
    • Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain
    • Huang C.C., Orban T., Jastrzebska B., Palczewski K., Tesmer J.J. Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain. Biochemistry 2011, 50:1940-1949.
    • (2011) Biochemistry , vol.50 , pp. 1940-1949
    • Huang, C.C.1    Orban, T.2    Jastrzebska, B.3    Palczewski, K.4    Tesmer, J.J.5
  • 33
    • 84860192408 scopus 로고    scopus 로고
    • Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1)
    • Orban T., Huang C.C., Homan K.T., Jastrzebska B., Tesmer J.J., Palczewski K. Substrate-induced changes in the dynamics of rhodopsin kinase (G protein-coupled receptor kinase 1). Biochemistry 2012, 51:3404-3411.
    • (2012) Biochemistry , vol.51 , pp. 3404-3411
    • Orban, T.1    Huang, C.C.2    Homan, K.T.3    Jastrzebska, B.4    Tesmer, J.J.5    Palczewski, K.6
  • 34
    • 84872917955 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases by phospholipids
    • Homan K.T., Glukhova A., Tesmer J.J. Regulation of G protein-coupled receptor kinases by phospholipids. Curr Med Chem 2013, 20:39-46.
    • (2013) Curr Med Chem , vol.20 , pp. 39-46
    • Homan, K.T.1    Glukhova, A.2    Tesmer, J.J.3
  • 36
    • 79952784761 scopus 로고    scopus 로고
    • Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs
    • Huang C.C., Tesmer J.J. Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs. J Biol Chem 2011, 286:7715-7721.
    • (2011) J Biol Chem , vol.286 , pp. 7715-7721
    • Huang, C.C.1    Tesmer, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.