Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?

Toxicology in Vitro

Volumn 28, Issue 1, 2014, Pages 54-59

  Doktorova, Tatyana Y ^a   Ates, Gamze ^a   Vinken, Mathieu ^a   Vanhaecke, Tamara ^a   Rogiers, Vera ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

Cosmetic ingredients; Mutagenicity genotoxicity test battery; Toxicogenomics based in vitro models

Indexed keywords

COSMETIC; DNA; TRICLOSAN;

ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; FALSE POSITIVE RESULT; FOLLOW UP; GENOMICS; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MUTAGENICITY; TOXICOGENOMICS; TRANSCRIPTOMICS;

ANIMALIA;

12-O-TETRADECANOYLPHORBOL-13-ACETATE; 2-NITROFLUORENE; 2NF; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE TEST; 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE; AFB1; AFLATOXIN B1; BAP; BENZO(A)PYRENE; CA; CHROMOSOME ABERRATION; CLONIDINE; CND; COSMETIC INGREDIENTS; CYCLO; CYCLOPHOSPHAMIDE; D-MANNITOL; DICLOFENAC SODIUM; GENOTOXIC; GTX; HCA; HIERARCHICAL CLUSTERING ANALYSIS; K-NEAREST NEIGHBOURS; KNN; LEAVE ONE OUT; LOO; MAN; METHAPYRILENE HYDROCHLORIDE; MICRONUCLEUS; MN; MPH; MTT TEST; MUTAGENICITY/GENOTOXICITY TEST BATTERY; NC; NGTX; NIF; NIFEDIPINE; NNK; NON-CARCINOGEN; NON-GENOTOXIC; PCA; PHENOBARBITAL SODIUM; PIPB; PIPERONYL BUTOXIDE; PRINCIPLE COMPONENT ANALYSIS; SDF; SPB; TOL; TOLBUTAMIDE; TOXICOGENOMICS-BASED IN VITRO MODELS; TPA; TRI; TRICLOSAN; WY-14643; WYE;

ANTI-INFECTIVE AGENTS, LOCAL; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; COSMETICS; FALSE POSITIVE REACTIONS; HUMANS; LIVER NEOPLASMS; MUTAGENICITY TESTS; TOXICOGENETICS; TRICLOSAN;

EID: 84888296705     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.09.022     Document Type: Article

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