An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints

Regulatory Toxicology and Pharmacology

Volumn 44, Issue 2, 2006, Pages 83-96

  Matthews, Edwin J ^a   Kruhlak, Naomi L ^a   Cimino, Michael C ^b   Benz, R Daniel ^a   Contrera, Joseph F ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Database; Genetic toxicity; Genetox; Reproductive and developmental toxicity; Reprotox; Rodent carcinogenicity bioassay; Surrogate

Indexed keywords

CARCINOGEN; CLASTOGEN;

AMES TEST; ARTICLE; BIOASSAY; CARCINOGENICITY; CHROMOSOME ABERRATION; CORRELATION ANALYSIS; DATA BASE; DEVELOPMENTAL DISORDER; DNA SYNTHESIS; GENE MUTATION; GENETIC TOXICOLOGY; GENOTOXICITY; LYMPHOMA; MICRONUCLEUS TEST; NONHUMAN; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; RETROSPECTIVE STUDY; RODENT; STATISTICAL ANALYSIS; TOXICITY TESTING;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; DATABASES, FACTUAL; MUTAGENICITY TESTS; PREDICTIVE VALUE OF TESTS; REPRODUCTION; SENSITIVITY AND SPECIFICITY; TOXICITY TESTS, CHRONIC;

RODENTIA; SALMONELLA;

EID: 32544452551     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yrtph.2005.11.003     Document Type: Article

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