Luteolin attenuates TGF-β1-induced epithelial-mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt-NF-κB-Snail pathway

Life Sciences

Volumn 93, Issue 24, 2013, Pages 924-933

  Chen, Kun Chieh ^a   Chen, Chiu Yuan ^b   Lin, Chih Ju ^c   Yang, Tsung Ying ^a   Chen, Tzu Hsiu ^d   Wu, Li Chen ^c   Wu, Chun Chi ^e,f  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NANHUA UNIVERSITY   (Taiwan)

^c NATIONAL CHI NAN UNIVERSITY   (Taiwan)

^d CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^e CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^f CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

EMT; Luteolin; NF B; PI3K Akt; TGF 1

Indexed keywords

CADHERIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUTEOLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR SNAIL; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

ARTICLE; CANCER CELL; DRUG MECHANISM; ENZYME ACTIVATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PROTEIN EXPRESSION;

EMT; LUTEOLIN; NF-ΚB; PI3K/AKT; TGF-Β1;

ADENOCARCINOMA; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPITHELIAL-MESENCHYMAL TRANSITION; EXPECTORANTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDICATORS AND REAGENTS; LUNG NEOPLASMS; LUTEOLIN; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; PHOSPHATIDYLINOSITOL 3-KINASES; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1;

GASTROPODA;

EID: 84888294009     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.10.004     Document Type: Article

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