High fat diet induces hypermethylation of the hypothalamic Pomc promoter and obesity in post-weaning rats

Psychoneuroendocrinology

Volumn 38, Issue 12, 2013, Pages 2844-2853

  Marco, Asaf ^a   Kisliouk, Tatiana ^b   Weller, Aron ^a   Meiri, Noam ^b  

^a BAR ILAN UNIVERSITY   (Israel)

^b VOLCANI CENTER   (Israel)

Author keywords

Arcuate nucleus; HF diet; Leptin; Methylation; Obesity; Pomc; Post weaning; Rats; Sp1

Indexed keywords

BETA ACTIN; LEPTIN; PROOPIOMELANOCORTIN; TRANSCRIPTION FACTOR SP1;

ANIMAL EXPERIMENT; ARTICLE; BETA ACTIN GENE; BINDING SITE; BODY WEIGHT; CALORIC INTAKE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; FOOD INTAKE; GENE EXPRESSION; INSULIN BLOOD LEVEL; LIPID DIET; MALE; NONHUMAN; OBESITY; POMC GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DNA BINDING; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ARCUATE NUCLEUS; HF DIET; LEPTIN; METHYLATION; OBESITY; POMC; POST-WEANING; RATS; SP1;

ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; CHROMATIN IMMUNOPRECIPITATION; CPG ISLANDS; DIET, HIGH-FAT; DNA METHYLATION; EATING; INSULIN; LEPTIN; MALE; OBESITY; PRO-OPIOMELANOCORTIN; PROMOTER REGIONS, GENETIC; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR;

EID: 84888292679     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2013.07.011     Document Type: Article

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