FoxO1 inhibits leptin regulation of pro-opiomelanocortin promoter activity by blocking STAT3 interaction with specificity protein 1

Journal of Biological Chemistry

Volumn 284, Issue 6, 2009, Pages 3719-3727

  Yang, Guoqing ^a   Lim, Chun Yan ^a   Li, Chao ^a   Radda, George K ^a   Li, Cai ^b   Cao, Xinmin ^c,d   Han, Weiping ^a,d  

^a AGENCY FOR SCIENCE   (Singapore)

^b MERCK RESEARCH LABORATORIES   (United States)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ENERGY EXPENDITURE; FOOD INTAKE; HYPOTHALAMIC NEURON; LEPTIN SIGNALING; MOLECULAR MECHANISM; NUCLEAR TRANSLOCATIONS; POTENTIAL MECHANISM; PROMOTER ACTIVITIES; PROMOTER COMPLEXES; SIGNALING PATHWAYS; SPECIFICITY PROTEIN 1; TARGET GENES;

BINDING ENERGY; BINDING SITES; GENE EXPRESSION; PHOSPHORYLATION; SIGNALING;

HORMONES;

LEPTIN; PROOPIOMELANOCORTIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR SP1; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO1 PROTEIN, MOUSE; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE TRANSLOCATION; HORMONE ACTION; HORMONE RESISTANCE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; DRUG EFFECT; GENE EXPRESSION REGULATION; MALE; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL NUCLEUS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; LEPTIN; MALE; MICE; PHOSPHORYLATION; PRO-OPIOMELANOCORTIN; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 63649158684     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804965200     Document Type: Article

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