Elongation factor 2 diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions

Free Radical Biology and Medicine

Volumn 67, Issue , 2014, Pages 131-138

  Argüelles, Sandro ^a,b   Camandola, Simonetta ^a   Cutler, Roy G ^a   Ayala, Antonio ^b   Mattson, Mark P ^a,c  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF SEVILLE   (Spain)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Diphthamide; Eukaryotic elongation factor 2; FGF 2; Free radicals; Internal ribosomal entry site; Lipid peroxidation; XIAP

Indexed keywords

CUMENE HYDROPEROXIDE; DIPHTHAMIDE; ELONGATION FACTOR 2; FIBROBLAST GROWTH FACTOR 2; HISTIDINE DERIVATIVE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; MESSENGER RNA; BENZENE DERIVATIVE; HISTIDINE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL PROTECTION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CHO CELL; CONTROLLED STUDY; FEMALE; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; TRANSLATION REGULATION; CELLULAR DISTRIBUTION; CHO CELL LINE; PROTEIN TARGETING; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; CRICETULUS; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; RIBOSOME;

EUKARYOTA;

ANIMALS; BENZENE DERIVATIVES; CELL SURVIVAL; CHO CELLS; CRICETULUS; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HISTIDINE; OXIDATIVE STRESS; PEPTIDE ELONGATION FACTOR 2; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA, MESSENGER; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84888125439     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.10.015     Document Type: Article

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