Cytoplasmic complex of p53 and eEF2

Journal of Cellular Physiology

Volumn 196, Issue 3, 2003, Pages 474-482

  Yin, Xia ^a   Fontoura, Beatriz M A ^a,b   Morimoto, Takashi ^a   Carroll, Robert B ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DIPHTHERIA TOXIN; GAMMA AZIDOGUANOSINE TRIPHOSPHATE; GUANOSINE TRIPHOSPHATE DERIVATIVE; PHOSPHORUS 32; PROTEIN; PROTEIN EEF2; PROTEIN P53; RIBOSOME PROTEIN; RIBOSOME RNA; RNA 5.8S; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; COVALENT BOND; CYTOPLASM; EMBRYO; MOLECULAR INTERACTION; NONHUMAN; POLYSOME; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN RENATURATION; RAT; RIBOSOME; RNA TRANSLATION; TRANSLATION REGULATION; ULTRAVIOLET IRRADIATION;

ANIMALS; CELL LINE; CELL NUCLEUS; CYCLOHEXIMIDE; CYTOPLASM; GENE EXPRESSION REGULATION; MICE; MUTATION; PEPTIDE ELONGATION FACTOR 2; PHOSPHOPROTEINS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; RATS; RIBOSOMES; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0043270449     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10329     Document Type: Article

References (33)

1. Abou Elela S, Nazar RN. 1997. Role of the 5.8S rRNA in ribosome translocation. Nucleic Acids Res 25:1788-1794.
2. Abou Elela S, Good L, Melekovets YF, Nazar RN. 1994. Inhibition of protein synthesis by an efficiently expressed mutation in the yeast 5.8S ribosomal RNA. Nucleic Acids Res 22:686-683.
3. Bodley JW, Dunlop PC, VanNess BG. 1984. Diphthamide in elongation factor 2: ADP-ribosylation, purification, and properties. In: Wold F, Moldavie K, editors. New York: Academic Press, Inc. p 378.
4. Buchhop S, Gibson MK, Wang XW, Wagner P, Sturzbecher HW, Harris CC. 1997. Interaction of p53 with the human Rad51 protein. Nucleic Acids Res 25:3868-3874.
5. Burnette NW. 1981. "Western Blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 112:195-203.
6. Dutta A, Ruppert JM, Aster JC, Winchester E. 1993. Inhibition of DNA replication factor RPA by p53 [see comments]. Nature 365: 79-82.
7. Fontoura BMA, Sorokina EA, David E, Carroll RB. 1992. p53 is covalently linked to 5.8S rRNA. Mol Cell Biol 12:5145-5151.
8. Fontoura BMA, Sorokina EA, Morimoto T, Carroll RB. 1997. Cytoplasmic p53 polypeptide is associated with ribosomes. Mol Cell Biol 17:3146-3154.
9. Gill DM, Pappenheimer AM, Jr., Baseman JB. 1969. Studies on transferase II using diphtheria toxin. Cold Spring Harb Symp Quant Biol 34:595-602.
10. Greenberg ME, Ziff EB. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311:433-438.
11. Levine A. 1997. p53, the cellular gatekeeper for growth and division. Cell 88:323-331.
12. Marechal V, Elenbaas B, Piette J, Nicolas J-C, Levine AJ. 1994. The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Mol Cell Biol 14:7414-7420.
13. McKeehan W, Hardesty B. 1969. The mechanism of cycloheximide inhibition of protein synthesis in rabbit reticulocytes. Biochem Biophys Res Commun 36:625-630.
14. Melero JA, Tur S, Carroll RB. 1980. Host nuclear proteins expressed in Simian virus 40-transformed and -infected cells. Proc Natl Acad Sci USA 77:97-101.
15. Metspalu A, Toots I, Saarma M, Villems R. 1980. The ternary complex consisting of rat liver ribosomal 5S RNA, 5.8S RNA, and protein L5. FEBS Lett 119:81-84.
16. Michalovitz D, Halevy O, Oren M. 1990. Conditional inhibition of transformation and cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671-680.
17. Milner J, Medcalf EA. 1990. Temperature-dependent switching between wild-type and mutant forms of p53-Va1135. J Mol Biol 216:481-484.
18. Nairn AC, Palfrey HC. 1996. Regulation of protein synthesis by calcium. In: Hershey JWB, Mathews MB, Sonnenberg N, editors. Translational control. Cold Spring Harbor: Cold Spring Harbor Laboratory Press. pp 295-318.
19. Nairn AC, Palfrey HC. 1987. Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2. J Biol Chem 262:17299-17303.
20. Nygard O, Nilsson L. 1987. The ribosomal binding site for eukaryotic elongation factor EF-2 contains 5S ribosomal RNA. Biochim Biophys Acta 908:46-53.
21. Nygard O, Nilsson L. 1990. Translational dynamics; interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis. Eur J Biochem 191:1-17.
22. Obrig TG, Culp WJ, McKeehan WL, Hardesty B. 1971. The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes. J Biol Chem 246:174-181.
23. Pappenheimer AM, Jr. 1977. Diphtheria toxin. Annu Rev Biochem 46:69-94.
24. Samad A, Carroll RB. 1991. The tumor suppressor p53 is bound to RNA by a stable covalent linkage. Mol Cell Biol 11:1598-1606.
25. Samad A, Anderson CW, Carroll RB. 1986. Mapping of phosphomonoester and apparent phosphodiester bonds of the oncogene product p53 from Simian virus 40-transformed 3T3 cells. Proc Natl Acad Sci USA 83:897-901.
26. Seto E, Usheva A, Zambetti GP, Momand J, Horikoshi N, Weinmann R, Levine AJ, Shenk T. 1992. Wild-type p53 binds to the TATA-binding protein and represses transcription. Proc Natl Acad Sci USA 89:12028-12032.
27. Ueda K, Hayaishi O. 1985. ADP-ribosylation. Annu Rev Biochem 54:73-100.
28. Ullrich N, Liu A, Wool IG. 1979. Identification by affinity chromatography of the eukaryotic ribosomal proteins that bind to 5.8S ribosomal ribonucleic acid. J Biol Chem 254:8641-8645.
29. Wade-Evans A, Jenkins JR. 1985. Precise epitope mapping of the murine transformation-associated protein, p53. EMBO J 4:699-706.
30. Walker TA, Endo Y, Wheat WH, Wool IG, Pace NR. 1983. Location of 5.8S rRNA contact sites in 28S rRNA and the effect of a-Saracin on the association of 5.8S rRNA with 28S rRNA. J Biol Chem 258: 333-338.
31. Walker K, Elela SA, Nazar RN. 1990. Inhibition of protein synthesis by anti 5.8S rRNA oligodeoxyribonucleotides. J Biol Chem 265: 2428-2430.
32. Wang XW, Yeh H, Schaeffer L, Roy R, Moncollin V, Egly JM, Wang Z, Freidberg EC, Evans MK, Taffe BG, et al. 1995. p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat Genet 10:188-195.
33. Yewdell JW, Gannon JV, Lane DP. 1986. Monoclonal antibody analysis of p53 expression in normal and transformed cells. J Virol 59:444-452.