MicroRNA-127 is downregulated by tudor-SN protein and contributes to metastasis and proliferation in breast cancer cell line MDA-MB-231

Anatomical Record

Volumn 296, Issue 12, 2013, Pages 1842-1849

  Zhao, Xiujuan ^a   Duan, Zhongchao ^a   Liu, Xin ^a   Wang, Baoya ^a   Wang, Xinting ^a   He, Jinyan ^a   Yao, Zhi ^a   Yang, Jie ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Metastasis; MiR 127; Proliferation; Tudor SN

Indexed keywords

MICRORNA; MICRORNA 101; MICRORNA 127; MICRORNA 181A; MICRORNA 191; MICRORNA 204; MICRORNA 21; MICRORNA 976A; MICRORNA LET7E; PROTEIN BCL 6; SHORT HAIRPIN RNA; TUDOR SN PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST METASTASIS; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MDA MB 231; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTO ONCOGENE; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

BREAST CANCER; METASTASIS; MIR-127; PROLIFERATION; TUDOR-SN;

APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; NUCLEAR PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR CELLS, CULTURED; WOUND HEALING;

EID: 84888053269     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.22823     Document Type: Article

References (34)

1. Blanco MA, Alečković M, Hua Y, Li T, Wei Y, Xu Z, Cristea IM, Kang Y. 2011. Identification of staphylococcal nuclease domain-containing1 (SND1) as a metadherin-interacting protein with metastasis-promoting functions. J Biol Chem 286:19982-19992.
2. Bos R, van Diest PJ, van der Groep P, Greijer AE, Hermsen MA, Heijnen I, Meijer GA, Baak JP, Pinedo HM, van der Wall E, Shvarts A. 2003. Protein expression of B-cell lymphoma gene 6 (BCL-6) in invasive breast cancer is associated with cyclin D1 and hypoxia-inducible factor-1α (HIF-1α). Oncogene 22:8948-8951.
3. Cahill S, Smyth P, Denning K, Flavin R, Li J, Potratz A, Guenther SM, Henfrey R, O'Leary JJ, Sheils O. 2007. Effect of BRAFV600E mutation on transcription and post-transcriptional regulation in a papillary thyroid carcinoma model. Mol Cancer 6:21-30.
4. Caudy AA, Ketting RF, Hammond SM, Denli AM, Bathoorn AM, Tops BB, Silva JM, Myers MM, Hannon GJ, Plasterk RH. 2003. A micrococcal nuclease homologue in RNAi effector complexes. Nature 425:411-414.
5. Filipowicz W, Jaskiewicz L, Kolb FA, Pillai RS. 2005. Post-transcriptional gene silencing by siRNAs and miRNAs. Curr Opin Struct Biol 15:331-341.
6. Fu SW, Chen L, Man YG. 2011. miRNA biomarkers in breast cancer detection and management. J cancer 2:116-122.
7. Gao X, Ge L, Shao J, Su C, Zhao H, Saarikettu J, Yao X, Yao Z, Silvennoinen O, Yang J. 2010. Tudor-SN interacts with and co-localizes with G3BP in stress granules under stress conditions. FEBS Lett 584:3525-3532.
8. Gao X, Zhao X, Zhu Y, He J, Shao J, Su C, Zhang Y, Zhang W, Saarikettu J, Silvennoinen O, Yao Z, Yang J. 2012. Tudor staphylococcal nuclease (Tudor-SN) participates in snRNP assembly via interacting with symmetrically dimethylated Sm proteins. J Biol Chem 287(22):18130-18141.
9. Ho J, Kong JW, Choong LY, Loh MC, Toy W, Chong PK, Wong CH, Wong CY, Shah N, Lim YP. 2009. Novel breast cancer metastasis-associated proteins. J Proteome Res 8:583-594.
10. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, Magri E, Pedriali M, Fabbri M, Campiglio M, Ménard S, Palazzo JP, Rosenberg A, Musiani P, Volinia S, Nenci I, Calin GA, Querzoli P, Negrini M, Croce CM. 2005. MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65:7065-7070.
11. Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ. 2005. RAS is regulated by the let-7 microRNA family. Cell 120:635-647.
12. Kawahara Y, Zinshteyn B, Chendrimada TP, Shiekhattar R, Nishikura K. 2007. RNA editing of the microRNA-151 precusor blocks cleavage by the Dicer-TRBP complex. EMBO Rep 8:763-769.
13. Kuruma H, Kamata Y, Takahashi H, Igarashi K, Kimura T, Miki K, Miki J, Sasaki H, Hayashi N, Egawa S. 2009. Staphylococcal nuclease domain containing protein 1 as a potential tissue marker for prostate cancer. Am J Pathol 174:2044-2050.
14. Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB, Eisenman RN, Ness SA. 1998. Pim-1 kinase and p100 cooperate to enhance c-Myb activity. Mol Cell 2:417-425.
15. Li CL, Yang WZ, Chen YP, Yuan HS. 2008. Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing. Nucleic Acids Res 36:3579-3589.
16. Lee JW, Choi CH, Choi JJ, Park YA, Kim SJ, Hwang SY, Kim WY, Kim TJ, Lee JH, Kim BG, Bae DS. 2008. Altered MicroRNA expression in cervical carcinomas. Clin Cancer Res 14:2535-2542.
17. Logarajah S, Hunter P, Kraman M, Steele D, Lakhani S, Bobrow L, Venkitaraman A, Wagner S. 2003. BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. Oncogene 22:5572-5578.
18. Ma L, Teruya-Feldstein J, Weinberg RA. 2007. Tumor invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449:682-688.
19. Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. 2005. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123:607-620.
20. Notterman DA, Alon U, Sierk AJ, Levine AJ. 2001. Transcriptional gene expression profile of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays. Cancer Res 61:3124-3130.
21. Paukku K, Yang J, Silvennoinen O. 2007. Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcriptional 5. Mol Endocrinol 17:1805-1814.
22. Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA, Jones PA. 2006. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 9:435-443.
23. Santhekadur PK, Das SK, Gredler R, Chen D, Srivastava J, Robertson C, Baldwin AS, Jr, Fisher PB, Sarkar D. 2012. The multifunction protein, staphylococcal nuclease domain containing-1 (SND1), promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF-κB and miR-221. J Biol Chem 287:13952-13958.
24. Scadden AD. 2005. The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage. Nat Struct Mol Biol 12:489-496.
25. Scadden AD, Smith CW. 2001. Specific cleavage of hyper-edited dsRNAs. EMBO J 20:4243-4252.
26. Tong X, Drapkin R, Yalamanchili R, Mosialos G, Kieff E. 1995. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. Mol Cell Biol 15:4735-4744.
27. Tsuchiya N, Nakagama H. 2010. MicroRNA, SND1, and alterations in translational regulation in colon carcinogenesis. Mutat Res 693:94-100.
28. Tsuchiya N, Ochiai M, Nakashima K, Ubagai T, Sugimura T, Nakagama H. 2007. SND1, a component of RNA-induced silencing complex, is upregulated in human colon cancers and implicated in early stage colon carcinogenesis. Cancer Res 67:9568-9576.
29. Välineva T, Yang J, Palovuori R, Silvennoinen O. 2005. The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6. J Biol Chem 280:14989-14996.
30. Wang X, Liu X, Fang J, Lu Y, He J, Yao X, Yao Z, Yang J. 2010. Coactivator P100 protein enhances STAT6-dependent transcriptional activation but has no effect on STAT1-mediated gene transcription. Anat Rec (Hoboken) 293(6):1010-1016.
31. Yang J, Aittomäki S, Pesu M, Carter K, Saarinen J, Kalkkinen N, Kieff E, Silvennoinen O. 2002. Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. EMBO J 21:4950-4958.
32. Yang W, Chendrimada TP, Wang Q, Higuchi M, Seeburg PH, Shiekhattar R, Nishikura K. 2005. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 13:130-121.
33. Yang J, Välineva T, Hong J, Bu T, Yao Z, Jensen ON, Frilander MJ, Silvennoinen O. 2007. Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. Nucleic Acids Res 35:4485-4494.
34. Yoo BK, Santhekadur PK, Gredler R, Chen D, Emdad L, Bhutia S, Pannell L, Fisher PB, Sarkar D. 2011. Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatology 53:1538-1548.