PI3K/Akt pathway mediates Nrf2/ARE activation in human L02 hepatocytes exposed to low-concentration HBCDs

Environmental Science and Technology

Volumn 47, Issue 21, 2013, Pages 12434-12440

  Zou, Wen ^a   Chen, Cen ^a   Zhong, Yufang ^a   An, Jing ^a   Zhang, Xinyu ^a   Yu, Yingxin ^a   Yu, Zhiqiang ^b   Fu, Jiamo ^b  

^a SHANGHAI UNIVERSITY   (China)

^b GUANGZHOU INSTITUTE OF GEOCHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA-DEPENDENT PROTEIN KINASE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FUNCTIONAL INTERACTION; HEXABROMOCYCLODODECANES; MOLECULAR MECHANISM; NUCLEAR TRANSLOCATIONS; PHOSPHATIDYLINOSITOL; SMALL INTERFERING RNA;

CELL PROLIFERATION; ELECTROPHORETIC MOBILITY; ENZYMES; GENE EXPRESSION; PROTEINS;

DNA;

2 MORPHOLINO 8 PHENYLCHROMONE; DNA DEPENDENT PROTEIN KINASE; HEXABROMOCYCLODODECANE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; WORTMANNIN; BROMINATED HYDROCARBON; HEME OXYGENASE 1; NUCLEAR PROTEIN; PRKDC PROTEIN, HUMAN;

ANTIOXIDANT; BIOASSAY; CATALYSIS; CONCENTRATION (COMPOSITION); DNA; GENE EXPRESSION; PROTEIN;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME ACTIVE SITE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; UPREGULATION; CELL NUCLEUS; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; METABOLISM; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANTIOXIDANT RESPONSE ELEMENTS; CELL NUCLEUS; CELL PROLIFERATION; DNA-ACTIVATED PROTEIN KINASE; GENE EXPRESSION REGULATION; GENE SILENCING; HEME OXYGENASE-1; HEPATOCYTES; HUMANS; HYDROCARBONS, BROMINATED; NF-E2-RELATED FACTOR 2; NUCLEAR PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84887899587     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es401791s     Document Type: Article

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