Predictors of progression to Type 1 diabetes: Preparing for immune interventions in the preclinical disease phase

Expert Review of Clinical Immunology

Volumn 9, Issue 12, 2013, Pages 1173-1183

  Gorus, Frans K ^a   Keymeulen, Bart ^a   Veld, Peter A In'T ^a   Pipeleers, Daniel G ^a  

^a DIABETES RESEARCH CENTER   (Belgium)

Author keywords

Anti CD3; Autoantibodies; C peptide; HLA; Hyperglycemic clamp; OGTT; Prediction; Prevention; Proinsulin; Type 1 diabetes

Indexed keywords

ABATACEPT; AUTOANTIBODY; AUTOANTIGEN; C PEPTIDE; CASEIN HYDROLYSATE; CD20 ANTIBODY; CD3 ANTIBODY; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 65; HEMOGLOBIN A1C; HLA A24 ANTIGEN; HLA B18 ANTIGEN; HLA B39 ANTIGEN; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; INDOLEACETIC ACID; INSULIN; INTERLEUKIN 1BETA; ISLET ANTIGEN 2; MICRORNA 375; NICOTINAMIDE; OTELIXIZUMAB; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR 1; PROINSULIN; RITUXIMAB; TEPLIZUMAB; UNCLASSIFIED DRUG; ZINC TRANSPORTER; ZINC TRANSPORTER 8A;

AGE; ANTIBODY SCREENING; ARTICLE; ATTRIBUTABLE RISK; CELL STIMULATION; DIABETIC PATIENT; DISEASE COURSE; DISEASE DURATION; DRUG MEGADOSE; DYSGLYCEMIA; FIRST DEGREE RELATIVE; GENETIC MARKER; GENETIC RISK; HIGH RISK POPULATION; HLA SYSTEM; HUMAN; HYPERGLYCEMIA; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PREVENTION STUDY; PRIMARY PREVENTION; PROPHYLAXIS; REGULATORY T LYMPHOCYTE; SCREENING TEST; SECONDARY PREVENTION; SEROCONVERSION; SHORT COURSE THERAPY; T LYMPHOCYTE;

ANIMALS; BIOLOGICAL MARKERS; CLINICAL TRIALS AS TOPIC; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; HUMANS; IMMUNOTHERAPY; INSULIN-SECRETING CELLS; PATIENT SELECTION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK;

EID: 84887859536     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2013.856757     Document Type: Article

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