An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age

Diabetologia

Volumn 55, Issue 2, 2012, Pages 413-420

  Vermeulen, I ^a   Weets, I ^a,b   Costa, O ^b   Asanghanwa, M ^a   Verhaeghen, K ^b   Decochez, K ^a   Ruige, J ^c   Casteels, K ^d   Wenzlau, J ^e   Hutton, J C ^e   Pipeleers, D G ^a   Gorus, F K ^a,b  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^c GHENT UNIVERSITY   (Belgium)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

Autoantibodies; First degree relatives; GAD; IA 2; Insulin; Prediabetes; Proinsulin; Seroconversion; Type 1 diabetes; Zinc transporter 8

Indexed keywords

AUTOANTIBODY; CELL PROTEIN; GLUTAMATE DECARBOXYLASE; INSULIN ANTIBODY; INSULINOMA ASSOCIATED PROTEIN 2; UNCLASSIFIED DRUG; ZINC TRANSPORTER; ZINC TRANSPORTER 8;

ADULT; AGE DISTRIBUTION; ANTIBODY DETECTION; CHILD; CONTROLLED STUDY; DISEASE COURSE; DISEASE REGISTRY; FEMALE; FOLLOW UP; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MINORITY GROUP; PRIORITY JOURNAL; RELATIVE; REVIEW; SCHOOL CHILD; SEROCONVERSION; SEX RATIO;

ADOLESCENT; ADULT; AGE FACTORS; AUTOANTIBODIES; CATION TRANSPORT PROTEINS; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; DISEASE-FREE SURVIVAL; FAMILY HEALTH; FEMALE; GLUTAMATE DECARBOXYLASE; HUMANS; INSULIN; MALE; PREDIABETIC STATE; TIME FACTORS;

EID: 84856732408     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2376-1     Document Type: Review

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