Synthesis of aminocyanopyrazoles via a multi-component reaction and anti-carbonic anhydrase inhibitory activity of their sulfamide derivatives against cytosolic and transmembrane isoforms

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 2, 2013, Pages 343-349

  Allouche, Fatma ^a   Chabchoub, Fakher ^a   Carta, Fabrizio ^b   Supuran, Claudiu T ^b  

^a Faculté des Sciences de Sfax   (Tunisia)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase inhibitor; MCR aminocyanopyrazoles; Pyrazolo 3,4 d 1,2,3 triazines; Pyrazolo 4,3 d pyrimidin 7 ones

Indexed keywords

AMINE; BENZENE DERIVATIVE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE IX; CARBONATE DEHYDRATASE XII; ESTER DERIVATIVE; FORMIC ACID; HYDRAZINE DERIVATIVE; MALONONITRILE; NITRILE; PYRAZOLE DERIVATIVE; PYRIMIDINONE DERIVATIVE; SODIUM NITRITE; SULFANILAMIDE DERIVATIVE; TRIAZINE DERIVATIVE; CARBONATE DEHYDRATASE INHIBITOR; ISOPROTEIN; SULFONAMIDE;

ARTICLE; CATALYSIS; CATALYST; CYTOSOL; DRUG SYNTHESIS; ENZYME INHIBITION; REACTION ANALYSIS; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; PROTEIN ISOFORMS; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84887843075     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2012.720573     Document Type: Article

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