메뉴 건너뛰기




Volumn 288, Issue 46, 2013, Pages 32827-32836

Atypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migration

Author keywords

[No Author keywords available]

Indexed keywords

DOWN-REGULATION; G PROTEIN COUPLED RECEPTORS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HETEROTRIMERIC G PROTEINS; PROTEIN KINASE C; RECEPTOR TYROSINE KINASE; RNA INTERFERENCE; SUBCELLULAR LOCALIZATIONS;

EID: 84887832463     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.489427     Document Type: Article
Times cited : (11)

References (46)
  • 1
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman, A. G. (1987) G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56, 615-649
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 2
    • 0025834532 scopus 로고
    • Diversity of G proteins in signal transduction
    • Simon, M. I., Strathmann, M. P., and Gautam, N. (1991) Diversity of G proteins in signal transduction. Science 252, 802-808
    • (1991) Science , vol.252 , pp. 802-808
    • Simon, M.I.1    Strathmann, M.P.2    Gautam, N.3
  • 4
    • 0031015426 scopus 로고    scopus 로고
    • Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency
    • Offermanns, S., Mancino, V., Revel, J. P., and Simon, M. I. (1997) Vascular system defects and impaired cell chemokinesis as a result of Gα13 deficiency. Science 275, 533-536
    • (1997) Science , vol.275 , pp. 533-536
    • Offermanns, S.1    Mancino, V.2    Revel, J.P.3    Simon, M.I.4
  • 5
    • 33646859037 scopus 로고    scopus 로고
    • The g protein gα13 is required for growth factor-induced cell migration
    • Shan, D., Chen, L., Wang, D., Tan, Y. C., Gu, J. L., and Huang, X. Y. (2006) The g protein gα13 is required for growth factor-induced cell migration. Dev. Cell 10, 707-718
    • (2006) Dev. Cell , vol.10 , pp. 707-718
    • Shan, D.1    Chen, L.2    Wang, D.3    Tan, Y.C.4    Gu, J.L.5    Huang, X.Y.6
  • 6
    • 33748652901 scopus 로고    scopus 로고
    • Transducing the signals: A G protein takes a new identity
    • Dhanasekaran, D. N. (2006) Transducing the signals: a G protein takes a new identity. Sci. STKE 2006, pe31
    • (2006) Sci. STKE , vol.2006
    • Dhanasekaran, D.N.1
  • 8
    • 3543114271 scopus 로고    scopus 로고
    • Foot and mouth: Podosomes, invadopodia and circular dorsal ruffles
    • Buccione, R., Orth, J. D., and McNiven, M. A. (2004) Foot and mouth: podosomes, invadopodia and circular dorsal ruffles. Nat. Rev. Mol. Cell Biol. 5, 647-657
    • (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 647-657
    • Buccione, R.1    Orth, J.D.2    McNiven, M.A.3
  • 9
    • 33845920871 scopus 로고    scopus 로고
    • G proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal ruffles
    • Wang, D., Tan, Y. C., Kreitzer, G. E., Nakai, Y., Shan, D., Zheng, Y., and Huang, X. Y. (2006) G proteins G12 and G13 control the dynamic turnover of growth factor-induced dorsal ruffles. J. Biol. Chem. 281, 32660-32667
    • (2006) J. Biol. Chem. , vol.281 , pp. 32660-32667
    • Wang, D.1    Tan, Y.C.2    Kreitzer, G.E.3    Nakai, Y.4    Shan, D.5    Zheng, Y.6    Huang, X.Y.7
  • 10
    • 80052231295 scopus 로고    scopus 로고
    • Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization
    • Wang, L., Guo, D., Xing, B., Zhang, J. J., Shu, H. B., Guo, L., and Huang, X. Y. (2011) Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization. J. Biol. Chem. 286, 31055-31061
    • (2011) J. Biol. Chem. , vol.286 , pp. 31055-31061
    • Wang, L.1    Guo, D.2    Xing, B.3    Zhang, J.J.4    Shu, H.B.5    Guo, L.6    Huang, X.Y.7
  • 11
    • 33645746316 scopus 로고    scopus 로고
    • The PAR-aPKC system: Lessons in polarity
    • Suzuki, A., and Ohno, S. (2006) The PAR-aPKC system: lessons in polarity. J. Cell Sci. 119, 979-987
    • (2006) J. Cell Sci. , vol.119 , pp. 979-987
    • Suzuki, A.1    Ohno, S.2
  • 12
    • 77951116071 scopus 로고    scopus 로고
    • Migrastatin analogues target fascin to block tumour metastasis
    • Chen, L., Yang, S., Jakoncic, J., Zhang, J. J., and Huang, X. Y. (2010) Migrastatin analogues target fascin to block tumour metastasis. Nature 464, 1062-1066
    • (2010) Nature , vol.464 , pp. 1062-1066
    • Chen, L.1    Yang, S.2    Jakoncic, J.3    Zhang, J.J.4    Huang, X.Y.5
  • 14
    • 22844433788 scopus 로고    scopus 로고
    • Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration
    • Yang, S., and Huang, X. Y. (2005) Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J. Biol. Chem. 280, 27130-27137
    • (2005) J. Biol. Chem. , vol.280 , pp. 27130-27137
    • Yang, S.1    Huang, X.Y.2
  • 17
    • 15544373780 scopus 로고    scopus 로고
    • Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator
    • Chen, Z., Singer, W. D., Sternweis, P. C., and Sprang, S. R. (2005) Structure of the p115RhoGEF rgRGS domain-Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator. Nat. Struct Mol. Biol. 12, 191-197
    • (2005) Nat. Struct Mol. Biol. , vol.12 , pp. 191-197
    • Chen, Z.1    Singer, W.D.2    Sternweis, P.C.3    Sprang, S.R.4
  • 18
    • 84861073615 scopus 로고    scopus 로고
    • Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCL in complex with a substrate peptide from Par-3
    • Wang, C., Shang, Y., Yu, J., and Zhang, M. (2012) Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCL in complex with a substrate peptide from Par-3. Structure 20, 791-801
    • (2012) Structure , vol.20 , pp. 791-801
    • Wang, C.1    Shang, Y.2    Yu, J.3    Zhang, M.4
  • 19
    • 0021210339 scopus 로고
    • A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells
    • Schliwa, M., Nakamura, T., Porter, K. R., and Euteneuer, U. (1984) A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells. J. Cell Biol. 99, 1045-1059
    • (1984) J. Cell Biol. , vol.99 , pp. 1045-1059
    • Schliwa, M.1    Nakamura, T.2    Porter, K.R.3    Euteneuer, U.4
  • 20
    • 0023784627 scopus 로고
    • Induction of circular membrane ruffling on human fibroblasts by platelet-derived growth factor
    • Mellström, K., Heldin, C. H., and Westermark, B. (1988) Induction of circular membrane ruffling on human fibroblasts by platelet-derived growth factor. Exp. Cell Res. 177, 347-359
    • (1988) Exp. Cell Res. , vol.177 , pp. 347-359
    • Mellström, K.1    Heldin, C.H.2    Westermark, B.3
  • 22
    • 0027185578 scopus 로고
    • Circular ruffle formation and closure lead to macropinocytosis in hepatocyte growth factor/scatter factor-treated cells
    • Dowrick, P., Kenworthy, P., McCann, B., and Warn, R. (1993) Circular ruffle formation and closure lead to macropinocytosis in hepatocyte growth factor/scatter factor-treated cells. Eur. J. Cell Biol. 61, 44-53
    • (1993) Eur. J. Cell Biol. , vol.61 , pp. 44-53
    • Dowrick, P.1    Kenworthy, P.2    McCann, B.3    Warn, R.4
  • 23
    • 0141886295 scopus 로고    scopus 로고
    • Differential roles ofWAVE1andWAVE2in dorsal and peripheral ruffle formation for fibroblast cell migration
    • Suetsugu, S., Yamazaki, D., Kurisu, S., and Takenawa, T. (2003) Differential roles ofWAVE1andWAVE2in dorsal and peripheral ruffle formation for fibroblast cell migration. Dev. Cell 5, 595-609
    • (2003) Dev. Cell , vol.5 , pp. 595-609
    • Suetsugu, S.1    Yamazaki, D.2    Kurisu, S.3    Takenawa, T.4
  • 24
    • 0030584089 scopus 로고    scopus 로고
    • Getting membrane flow and the cytoskeleton to cooperate in moving cells
    • Bretscher, M. S. (1996) Getting membrane flow and the cytoskeleton to cooperate in moving cells. Cell 87, 601-606
    • (1996) Cell , vol.87 , pp. 601-606
    • Bretscher, M.S.1
  • 25
    • 0037343053 scopus 로고    scopus 로고
    • A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells
    • Krueger, E. W., Orth, J. D., Cao, H., and McNiven, M. A. (2003) A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells. Mol. Biol. Cell 14, 1085-1096
    • (2003) Mol. Biol. Cell , vol.14 , pp. 1085-1096
    • Krueger, E.W.1    Orth, J.D.2    Cao, H.3    McNiven, M.A.4
  • 26
    • 0030603158 scopus 로고    scopus 로고
    • Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes
    • Gschwendt, M., Dieterich, S., Rennecke, J., Kittstein, W., Mueller, H. J., and Johannes, F. J. (1996) Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Lett. 392, 77-80
    • (1996) FEBS Lett , vol.392 , pp. 77-80
    • Gschwendt, M.1    Dieterich, S.2    Rennecke, J.3    Kittstein, W.4    Mueller, H.J.5    Johannes, F.J.6
  • 27
    • 79953293527 scopus 로고    scopus 로고
    • Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis
    • Durgan, J., Kaji, N., Jin, D., and Hall, A. (2011) Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. J. Biol. Chem. 286, 12461-12474
    • (2011) J. Biol. Chem. , vol.286 , pp. 12461-12474
    • Durgan, J.1    Kaji, N.2    Jin, D.3    Hall, A.4
  • 28
    • 4344652068 scopus 로고    scopus 로고
    • Targeted deletion of protein kinase C λ reveals a distribution of functions between the two atypical protein kinase C isoforms
    • Soloff, R. S., Katayama, C., Lin, M. Y., Feramisco, J. R., and Hedrick, S. M. (2004) Targeted deletion of protein kinase C λ reveals a distribution of functions between the two atypical protein kinase C isoforms. J. Immunol. 173, 3250-3260
    • (2004) J. Immunol. , vol.173 , pp. 3250-3260
    • Soloff, R.S.1    Katayama, C.2    Lin, M.Y.3    Feramisco, J.R.4    Hedrick, S.M.5
  • 30
    • 0034130117 scopus 로고    scopus 로고
    • Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: Relationship to differentiation and survival of PC12 cells
    • Wooten, M. W., Seibenhener, M. L., Neidigh, K. B., and Vandenplas, M. L. (2000) Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells. Mol. Cell. Biol. 20, 4494-4504
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 4494-4504
    • Wooten, M.W.1    Seibenhener, M.L.2    Neidigh, K.B.3    Vandenplas, M.L.4
  • 31
    • 42049092972 scopus 로고    scopus 로고
    • Regulation of actin assembly associated with protrusion and adhesion in cell migration
    • Le Clainche, C., and Carlier, M. F. (2008) Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol. Rev. 88, 489-513
    • (2008) Physiol. Rev. , vol.88 , pp. 489-513
    • Le Clainche, C.1    Carlier, M.F.2
  • 33
    • 80051655842 scopus 로고    scopus 로고
    • The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide- free state of Galphai1
    • Thomas, C. J., Briknarová, K., Hilmer, J. K., Movahed, N., Bothner, B., Sumida, J. P., Tall, G. G., and Sprang, S. R. (2011) The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide- free state of Galphai1. PLoS One 6, e23197
    • (2011) PLoS One , vol.6
    • Thomas, C.J.1    Briknarová, K.2    Hilmer, J.K.3    Movahed, N.4    Bothner, B.5    Sumida, J.P.6    Tall, G.G.7    Sprang, S.R.8
  • 34
    • 0033695192 scopus 로고    scopus 로고
    • RIC-8 (Synembryn): A novel conserved protein that is required for Gqα signaling in the C. Elegans nervous system
    • Miller, K. G., Emerson, M. D., McManus, J. R., and Rand, J. B. (2000) RIC-8 (Synembryn): a novel conserved protein that is required for Gqα signaling in the C. elegans nervous system. Neuron 27, 289-299
    • (2000) Neuron , vol.27 , pp. 289-299
    • Miller, K.G.1    Emerson, M.D.2    McManus, J.R.3    Rand, J.B.4
  • 35
    • 0034533704 scopus 로고    scopus 로고
    • A role for RIC-8 (Synembryn) and GOA-1 (G(o) alpha) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans
    • Miller, K. G., and Rand, J. B. (2000) A role for RIC-8 (Synembryn) and GOA-1 (G(o) alpha) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans. Genetics 156, 1649-1660
    • (2000) Genetics , vol.156 , pp. 1649-1660
    • Miller, K.G.1    Rand, J.B.2
  • 36
    • 5444259457 scopus 로고    scopus 로고
    • RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. Elegans
    • Hess, H. A., Röper, J. C., Grill, S. W., and Koelle, M. R. (2004) RGS-7 completes a receptor-independent heterotrimeric G protein cycle to asymmetrically regulate mitotic spindle positioning in C. elegans. Cell 119, 209-218
    • (2004) Cell , vol.119 , pp. 209-218
    • Hess, H.A.1    Röper, J.C.2    Grill, S.W.3    Koelle, M.R.4
  • 37
    • 5444260164 scopus 로고    scopus 로고
    • RIC-8 is required for GPR-1/2- dependent G- function during asymmetric division of C. Elegans embryos
    • Afshar, K., Willard, F. S., Colombo, K., Johnston, C. A., McCudden, C. R., Siderovski, D. P., and Gönczy, P. (2004) RIC-8 is required for GPR-1/2- dependent G- function during asymmetric division of C. elegans embryos. Cell 119, 219-230
    • (2004) Cell , vol.119 , pp. 219-230
    • Afshar, K.1    Willard, F.S.2    Colombo, K.3    Johnston, C.A.4    McCudden, C.R.5    Siderovski, D.P.6    Gönczy, P.7
  • 38
    • 28844482414 scopus 로고    scopus 로고
    • Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins
    • Wang, H., Ng, K. H., Qian, H., Siderovski, D. P., Chia, W., and Yu, F. (2005) Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins. Nat. Cell Biol. 7, 1091-1098
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1091-1098
    • Wang, H.1    Ng, K.H.2    Qian, H.3    Siderovski, D.P.4    Chia, W.5    Yu, F.6
  • 39
    • 28844481199 scopus 로고    scopus 로고
    • Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins
    • Hampoelz, B., Hoeller, O., Bowman, S. K., Dunican, D., and Knoblich, J. A. (2005) Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins. Nat. Cell Biol. 7, 1099-1105
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1099-1105
    • Hampoelz, B.1    Hoeller, O.2    Bowman, S.K.3    Dunican, D.4    Knoblich, J.A.5
  • 40
    • 27844524595 scopus 로고    scopus 로고
    • Drosophila Ric-8 regulates Gαi cortical localization to promote Gαi-dependent planar orientation of the mitotic spindle during asymmetric cell division
    • David, N. B., Martin, C. A., Segalen, M., Rosenfeld, F., Schweisguth, F., and Bellaïche, Y. (2005) Drosophila Ric-8 regulates Gαi cortical localization to promote Gαi-dependent planar orientation of the mitotic spindle during asymmetric cell division. Nat. Cell Biol. 7, 1083-1090
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1083-1090
    • David, N.B.1    Martin, C.A.2    Segalen, M.3    Rosenfeld, F.4    Schweisguth, F.5    Bellaïche, Y.6
  • 41
    • 0026068650 scopus 로고
    • The Drosophila gastrulation gene concertina encodes a G α-like protein
    • Parks, S., and Wieschaus, E. (1991) The Drosophila gastrulation gene concertina encodes a G α-like protein. Cell 64, 447-458
    • (1991) Cell , vol.64 , pp. 447-458
    • Parks, S.1    Wieschaus, E.2
  • 42
    • 0037424298 scopus 로고    scopus 로고
    • Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor
    • Tall, G. G., Krumins, A. M., and Gilman, A. G. (2003) Mammalian Ric-8A (synembryn) is a heterotrimeric Gα protein guanine nucleotide exchange factor. J. Biol. Chem. 278, 8356-8362
    • (2003) J. Biol. Chem. , vol.278 , pp. 8356-8362
    • Tall, G.G.1    Krumins, A.M.2    Gilman, A.G.3
  • 43
    • 5644285256 scopus 로고    scopus 로고
    • Purification and functional analysis of Ric-8A: A guanine nucleotide exchange factor for G-protein α subunits
    • Tall, G. G., and Gilman, A. G. (2004) Purification and functional analysis of Ric-8A: a guanine nucleotide exchange factor for G-protein α subunits. Methods Enzymol. 390, 377-388
    • (2004) Methods Enzymol. , vol.390 , pp. 377-388
    • Tall, G.G.1    Gilman, A.G.2
  • 44
    • 17644404436 scopus 로고    scopus 로고
    • Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Gαolf
    • Von Dannecker, L. E., Mercadante, A. F., and Malnic, B. (2005) Ric-8B, an olfactory putative GTP exchange factor, amplifies signal transduction through the olfactory-specific G-protein Gαolf. J. Neurosci. 25, 3793-3800
    • (2005) J. Neurosci. , vol.25 , pp. 3793-3800
    • Von Dannecker, L.E.1    Mercadante, A.F.2    Malnic, B.3
  • 45
    • 30344470192 scopus 로고    scopus 로고
    • Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety
    • Tõnissoo, T., Kõks, S., Meier, R., Raud, S., Plaas, M., Vasar, E., and Karis, A. (2006) Heterozygous mice with Ric-8 mutation exhibit impaired spatial memory and decreased anxiety. Behav. Brain Res. 167, 42-48
    • (2006) Behav. Brain Res. , vol.167 , pp. 42-48
    • Tõnissoo, T.1    Kõks, S.2    Meier, R.3    Raud, S.4    Plaas, M.5    Vasar, E.6    Karis, A.7
  • 46
    • 33750493895 scopus 로고    scopus 로고
    • Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts
    • Yang, L., Wang, L., and Zheng, Y. (2006) Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol. Biol. Cell 17, 4675-4685
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4675-4685
    • Yang, L.1    Wang, L.2    Zheng, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.