Spinigerin induces apoptotic like cell death in a caspase independent manner in Leishmania donovani

Experimental Parasitology

Volumn 135, Issue 4, 2013, Pages 715-725

  Sardar, A H ^a   Das, S ^b   Agnihorti, S ^c   Kumar, M ^a   Ghosh, A K ^a   Abhishek, K ^a   Kumar, A ^a   Purkait, B ^a   Ansari, M Y ^c   Das, P ^a  

^a RAJENDRA MEMORIAL RESEARCH INSTITUTE OF MEDICAL SCIENCES   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c National Institute of Pharmaceutical Education and Research (NIPER)   (India)

Author keywords

AMP; Annexin V; Apoptosis; Spinigerin; TUNEL

Indexed keywords

ASCORBATE PEROXIDASE; CALCIUM ION; CASPASE; DACTINOMYCIN; LIPOCORTIN 5; MILTEFOSINE; POLYPEPTIDE ANTIBIOTIC AGENT; REACTIVE OXYGEN METABOLITE; SPINIGERIN; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTILEISHMANIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; APOPTOSIS; ARTICLE; CELL POPULATION; CELL ROUNDING; CELL STRUCTURE; CONTROLLED STUDY; DNA DEGRADATION; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EXPOSURE; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; IC 50; INFECTION RATE; ISOPTERA; LEISHMANIA DONOVANI; MACROPHAGE; MATHEMATICAL ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NICK END LABELING; NONHUMAN; NUCLEAR CONDENSATION; PRIORITY JOURNAL; PROMASTIGOTE; PSEUDACANTHOTERMES SPINIGER;

AMP; ANNEXIN-V; APOPTOSIS; SPINIGERIN; TUNEL;

ANIMALS; ANTIPROTOZOAL AGENTS; APOPTOSIS; ASCORBATE PEROXIDASES; CALCIUM; CASPASES; DNA FRAGMENTATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN-ION CONCENTRATION; INHIBITORY CONCENTRATION 50; ISOPTERA; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; LIPID PEROXIDATION; MACROPHAGES, PERITONEAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; NADH, NADPH OXIDOREDUCTASES; PEPTIDES; REACTIVE OXYGEN SPECIES;

EID: 84887689546     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2013.10.011     Document Type: Article

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