Calcium, free radicals and excitotoxins in neuronal apoptosis

Cell Calcium

Volumn 23, Issue 2-3, 1998, Pages 165-171

  Lipton, S A ^a   Nicotera, P ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; EXCITOTOXIN; FREE RADICAL; GLUTAMIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; CALCIUM CELL LEVEL; CELL DEATH; CELL DESTRUCTION; CELL SWELLING; CHROMATIN; CONTROLLED STUDY; CYTOLYSIS; HOMEOSTASIS; INFLAMMATION; NECROSIS; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0031942369     PISSN: 01434160     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0143-4160(98)90115-4     Document Type: Review

References (68)

1. J.F.R. Kerr A.H. Wyllie A.R. Currie Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetics Br J Cancer 26 1972 239 257
2. A.H. Wyllie J.F.R. Kerr A.R. Currie Cell death: the significance of apoptosis Int Rev Cytol 68 1980 251 306
3. T.L. Deckwerth E.M. Johnson Jr Neurotrophic factor deprivation-induced death Ann NY Acad Sci 679 1993 121 131
4. C.B. Thompson Apoptosis in the pathogenesis and treatment of disease Science 267 1995 1456 1462
5. S. Kure T. Tominaga T. Yoshimoto K. Tada K. Narisawa Glutamate triggers internucleosomal DNA cleavage in neuronal cells Biochem Biophys Res Commun 179 1991 39 45
6. J.P. MacManus A.M. Buchan I.E. Hill I. Rasquinha E. Preston Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain Neurosci Lett 159 1993 89 92
7. M.C. Raff B.A. Barres J.F. Burne H.S. Coles Y. Ishizaki M.D. Jacobson Programmed cell death and the control cell of survival: lessons from the nervous system Science 262 1993 695 700
8. D. Games D. Adams R. Alessandrini Alzheimer-type neuropathology in transgenic mice overexpressing V717FB-amyloid precursor protein Nature 373 1995 523 527
9. M.D. Linnik R.H. Zobrist M.D. Hatfield Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats Stroke 24 1993 2002 2008
10. J. Mitchell S. Lawson B. Moser Glutamate-induced apoptosis results in a loss of striatal neurons in the Parkinsonian rat Neuroscience 63 1994 1 5
11. J.H. Su A.J. Anderson B.J. Cummings C.W. Cotman Immunohistochemical evidence for apoptosis in Alzheimer's disease NeuroReport 5 1994 2529 2533
12. C.K. Petito B. Roberts Evidence of apoptotic cell death in HIV encephalitis Am J Pathol 146 1995 1121 1130
13. D.W. Dickson Apoptosis in the brain. Physiology and pathology Am J Pathol 146 1995 1040 1044
14. H. Adle-Biassette Y. Levy M.al. Colombel Neuronal apoptosis in HIV infection in adults Neuropathol Appl Neurobiol 21 1995 218 227
15. S.F. An F. Gray F. Scaravilli Programmed cell death in brain of HIV-1 positive pre-AIDS patients [Letter] Lancet 346 1995 911 912
16. S.F. An B. Gioimetto T. Scaravilli Programmed cell death in brains of HIV-1 positive AIDS and jpre-AIDS patients Acta Neuropathol 91 1996 169 173
17. H.A. Gelbard H. James L. Sharer Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy Neuropathol Appl Neurobiol 21 1995 208 217
18. S.A. Lipton Similarity of neuronal cell injury and death in AIDS dimentia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species Brain Pathol 6 1996 507 517
19. J. Yuan S. Shaham S. Ledouz H.M. Ellis H.R. Horvitz The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme Cell 75 1993 641 652
20. 2+ channels exposed to serum from patients with type I diabetes Science 261 1993 86 90
21. P. Nicotera B. Zhivotovsky G. Bellomo S. Orrenius Ion signalling in apoptosis R.T. Schimke E. Mihich Apoptosis 1994 Plenum New York 15 97
22. P. Nicotera M. Ankarcrona E. Bonfoco S. Orrenius S.A. Lipton Neuronal apoptosis versus necrosis induced by glutamate or free radicals Apoptosis 1 1996 5 10
23. S.A. Lipton Janus faces of NF-κB: neurodestruction versus neuroprotection Nat Med 3 1997 20 22
24. H. Kawasaki T. Morooka T. Shimohama Y. Gotoh E. Nishida Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebrelar granule cells J Biol Chem 272 1997 18518 18521
25. J.H. Cardone G.S. Salvesen C. Widmann G. Johnson S.M. Frisch The regulation of anoikis: MEKK-1 activation requires cleavage by caspases Cell 90 1997 315 323
26. J.M. Dypbukt M. Ankarcrona M. Burkitt Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells: The role of intracellular polyamines J Biol Chem 269 1994 30553 30560
27. C. Behl J.B. Davis R. Lesley D. Schubert Hydrogen peroxide mediates amyloid β protein toxicity Cell 77 1994 817 827
28. C.M. Troy M.L. Shelanski Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells Proc Natl Acad Sci USA 91 1994 6384 6387
29. T.M. Buttke P.A. Sandstrom Oxidative stress as a mediator of apoptosis Immunol Today 15 1994 7 10
30. C. Abate N. Patel F.J. Rauscher III T. Curran Redox regulation of Fos and Jun DNA-binding activity in vitro Science 249 1990 1157 1161
31. 2 and antioxidants have opposite effects on activation of NF-βB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor EMBO J 12 1993 2005 2015
32. C.M. Troy L. Stefanis A. Prochantz L.A. Greene M.L. Shelanski The contrasting roles of ICE family proteases and interleukin-1β in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation Proc Natl Acad Sci USA 93 1996 5635 5640
33. T.M. Dawson V.L. Dawson S.H. Snyder A novel neuronal messenger molecule in brain: the free radical, nitric oxide Ann Neurol 32 1992 297 311
34. C. Nathan Nitric oxide as a secretory product of mammalian cells FASEB J 6 1992 3051 3064
35. S.A. Lipton Y.-B. Choi Z.-H. Pan A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds Nature 364 1993 626 632
36. J.S. Stamler E.J. Toone S.A. Lipton N.J. Sucher (S)NO signals: translocation, regulation, and a consensus motif Neuron 18 1997 691 696
37. J.S. Stamler Redox signaling: nitrosylation and related target interactions of nitric oxide Cell 78 1994 931 936
38. V.L. Dawson T.M. Dawson E.D. London D.S. Bredt S.H. Snyder Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures Proc Natl Acad Sci USA 88 1991 6368 6371
39. A.A. Noronha-Dutra M.M. Epperlein N. Woolf Reaction of nitric oxide with hydrogen peroxide to produce potentially cytotoxic singlet oxygen as a model for nitric oxide-mediated killing FEBS Lett 321 1993 59 62
40. S.M. Rothman J.W. Olney Excitotoxicity and the NMDA receptor Trends Neurosci 10 1987 299 302
41. D.W. Choi Glutamate neurotoxicity and diseases of the nervous system Neuron 1 1988 623 634
42. B. Meldrum J. Garthwaite Excitatory amino acid neurotoxicity and neurodegenerative disease Trends Pharmacol Sci 11 1990 379 387
43. S.A. Lipton P.A. Rosenberg Mechanisms of disease: excitatory amino acids as a final common pathway for neurologic disorders N Engl J Med 330 1994 613 622
44. J.T. Coyle P. Puttfarken Oxidative stress, glutamate and neurodegenerative disorders Science 262 1993 689 695
45. E. Bonfoco D. Krainc M. Ankarcrona P. Nicotera S.A. Lipton Apoptosis and necrosis: two distinct events induced respectively by mild and intense insults with NMDA or nitric oxide/superoxide in cortical cell cultures Proc Natl Acad Sci USA 92 1995 7162 7166
46. C. Ayata G. Ayata H. Hara Mechanisms of reduced striatal NMDA excitotoxicity in type 1 nitric oxide synthase knock-out mice J Neurosci 17 1997 6908 6917
47. 2+ influx elicited by glutamate: role in neuronal death Mol Pharmacol 36 1989 106 112
48. P. Nicotera G. Bellomo S. Orrenius Calcium-mediated mechanisms in chemically induced cell death Annu Rev Pharmacol Toxicol 32 1992 449 470
49. M. Ankarcrona J.M. Dypbukt E. Bonfoco Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function Neuron 15 1995 961 973
50. J.S. Beckman T.W. Beckman J. Chen P.A. Marshall B.A. Freeman Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide Proc Natl Acad Sci USA 87 1990 1620 1624
51. M.D. Jacobson J.F. Burne M.P. King T. Miyashita J.C. Reed M.C. Raff Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA Nature 361 1993 365 369
52. D.D. Newmeyer D.M. Farschon J.C. Reed Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria Cell 79 1994 353 364
53. D.K.A. Nicholls Mitochondrial calcium transport Biochim Biophys Acta 683 1982 57 88
54. 2+: implications for neurodegeneration J Neurochem 63 1994 584 591
55. L.L. Dugan S.L. Sensi L.M.T. Canzoniero Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N -methyl- d -aspartate J Neurosci 15 1995 6377 6388
56. R.J. White I.J. Reynolds Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure J Neurosci 16 1996 5688 5697
57. A.F. Schinder E.C. Olson N.C. Spitzer M. Montal Mitochondrial dysfunction is a primary event in glutamate neurotoxicity J Neurosci 16 1996 6125 6133
58. L. Tenneti D.M. D'Emilia C.M. Troy S.A. Lipton Role of caspases in N-methyl- d -aspartate-induced apoptosis of cerebrocortical neurons Soc Neurosci Abstr 23 1997 1667
59. J.B. Schulz M. Weller T. Klockgether Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species J Neurosci 16 1996 4696 4706
60. M.F. Beal Role of excitotoxicity in neurological diseases Curr Opin Neurobiol 2 1992 657 662
61. P. Golstein Controlling cell death Science 275 1997 1081 1082
62. J. Yang X. Liu B. Kapil Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
63. R.M. Kluck E. Bossy-Wetzel D.R. Green D.D. Newmeyer The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132 1136
64. S.A. Susin N. Zamzani M. Castedo The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/PO-1/CD95- and ceramide-induced apoptosis J Exp Med 186 1997 25 37
65. S.A. Lipton J.S. Stamler Actions of redox-related congeners of nitric oxide at the NMDA receptor Neuropharmacology 33 1994 1229 1233
66. L. Tenneti D.M. D'Emilia S.A. Lipton Suppression of neuronal apoptosis by S -nitrosylation of caspases Neurosci Lett 236 1997 139 142
67. H. Zou W.J. Henzel X. Liu A. Lutschig X. Wang Apaf-1, a human protein homologous to C. elegans CED-4, participates incytochrome c-dependent activation of caspase-3 Cell 90 1997 405 413
68. P. Li D. Nijhawan J. Budihardjo Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade Cell 91 1997 479 489