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Volumn 1836, Issue 2, 2013, Pages 345-353

Insulin-like growth factor - Oestradiol crosstalk and mammary gland tumourigenesis

Author keywords

Breast cancer; Endocrine resistance; Insulin like growth factor; Oestradiol

Indexed keywords

ANASTROZOLE; ANTIESTROGEN; AROMATASE INHIBITOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; G PROTEIN COUPLED RECEPTOR 30; INSULIN; INSULIN RECEPTOR SUBSTRATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGENIC AGENT; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; TAMOXIFEN; VITAMIN D DERIVATIVE;

EID: 84887589981     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2013.10.005     Document Type: Review
Times cited : (57)

References (152)
  • 1
    • 57149142363 scopus 로고    scopus 로고
    • IGF binding proteins (IGFBPs) and regulation of breast cancer biology
    • Perks C.M., Holly J.M. IGF binding proteins (IGFBPs) and regulation of breast cancer biology. J. Mammary Gland Biol. Neoplasia 2008, 13(4):455-469.
    • (2008) J. Mammary Gland Biol. Neoplasia , vol.13 , Issue.4 , pp. 455-469
    • Perks, C.M.1    Holly, J.M.2
  • 2
    • 57149122547 scopus 로고    scopus 로고
    • IGF ligand and receptor regulation of mammary development
    • Rowzee A.M., et al. IGF ligand and receptor regulation of mammary development. J. Mammary Gland Biol. Neoplasia 2008, 13(4):361-370.
    • (2008) J. Mammary Gland Biol. Neoplasia , vol.13 , Issue.4 , pp. 361-370
    • Rowzee, A.M.1
  • 3
    • 0030904370 scopus 로고    scopus 로고
    • Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media
    • Wilson E.M., Oh Y., Rosenfeld R.G. Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media. J. Clin. Endocrinol. Metab. 1997, 82(4):1301-1303.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.4 , pp. 1301-1303
    • Wilson, E.M.1    Oh, Y.2    Rosenfeld, R.G.3
  • 4
    • 0031786081 scopus 로고    scopus 로고
    • Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells
    • Yang D.H., et al. Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells. J. Clin. Endocrinol. Metab. 1998, 83(7):2593-2596.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , Issue.7 , pp. 2593-2596
    • Yang, D.H.1
  • 5
    • 34447257938 scopus 로고    scopus 로고
    • Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3
    • Sano A., et al. Kallikrein 11 expressed in human breast cancer cells releases insulin-like growth factor through degradation of IGFBP-3. Int. J. Oncol. 2007, 30(6):1493-1498.
    • (2007) Int. J. Oncol. , vol.30 , Issue.6 , pp. 1493-1498
    • Sano, A.1
  • 6
    • 0026637765 scopus 로고
    • Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex
    • Leong S.R., et al. Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex. Mol. Endocrinol. 1992, 6(6):870-876.
    • (1992) Mol. Endocrinol. , vol.6 , Issue.6 , pp. 870-876
    • Leong, S.R.1
  • 7
    • 0021365286 scopus 로고
    • Biological and immunological properties of insulin-like growth factors (IGF) I and II
    • Zapf J., Schmid C., Froesch E.R. Biological and immunological properties of insulin-like growth factors (IGF) I and II. Clin. Endocrinol. Metab. 1984, 13(1):3-30.
    • (1984) Clin. Endocrinol. Metab. , vol.13 , Issue.1 , pp. 3-30
    • Zapf, J.1    Schmid, C.2    Froesch, E.R.3
  • 8
    • 56749096810 scopus 로고    scopus 로고
    • Elevated free IGF2 levels in localized, early-stage breast cancer in women
    • Espelund U., et al. Elevated free IGF2 levels in localized, early-stage breast cancer in women. Eur. J. Endocrinol. 2008, 159(5):595-601.
    • (2008) Eur. J. Endocrinol. , vol.159 , Issue.5 , pp. 595-601
    • Espelund, U.1
  • 9
    • 0023251413 scopus 로고
    • Insulin-like growth factor II receptor as a multifunctional binding protein
    • Morgan D.O., et al. Insulin-like growth factor II receptor as a multifunctional binding protein. Nature 1987, 329(6137):301-307.
    • (1987) Nature , vol.329 , Issue.6137 , pp. 301-307
    • Morgan, D.O.1
  • 10
    • 0030207118 scopus 로고    scopus 로고
    • Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling?
    • Blakesley V.A., et al. Signaling via the insulin-like growth factor-I receptor: does it differ from insulin receptor signaling?. Cytokine Growth Factor Rev. 1996, 7(2):153-159.
    • (1996) Cytokine Growth Factor Rev. , vol.7 , Issue.2 , pp. 153-159
    • Blakesley, V.A.1
  • 11
    • 79961004321 scopus 로고    scopus 로고
    • Signalling by insulin and IGF receptors: supporting acts and new players
    • Siddle K. Signalling by insulin and IGF receptors: supporting acts and new players. J. Mol. Endocrinol. 2011, 47(1):R1-R10.
    • (2011) J. Mol. Endocrinol. , vol.47 , Issue.1
    • Siddle, K.1
  • 12
    • 0037112994 scopus 로고    scopus 로고
    • Intrinsic actions of IGFBP-3 and IGFBP-5 on Hs578T breast cancer epithelial cells: inhibition or accentuation of attachment and survival is dependent upon the presence of fibronectin
    • McCaig C., Perks C.M., Holly J.M. Intrinsic actions of IGFBP-3 and IGFBP-5 on Hs578T breast cancer epithelial cells: inhibition or accentuation of attachment and survival is dependent upon the presence of fibronectin. J. Cell Sci. 2002, 115(Pt 22):4293-4303.
    • (2002) J. Cell Sci. , vol.115 , Issue.PART 22 , pp. 4293-4303
    • McCaig, C.1    Perks, C.M.2    Holly, J.M.3
  • 13
    • 0028013373 scopus 로고
    • Insulin-like growth factor-binding protein enhancement of insulin-like growth factor-I (IGF-I)-mediated DNA synthesis and IGF-I binding in a human breast carcinoma cell line
    • Chen J.C., et al. Insulin-like growth factor-binding protein enhancement of insulin-like growth factor-I (IGF-I)-mediated DNA synthesis and IGF-I binding in a human breast carcinoma cell line. J. Cell. Physiol. 1994, 158(1):69-78.
    • (1994) J. Cell. Physiol. , vol.158 , Issue.1 , pp. 69-78
    • Chen, J.C.1
  • 14
    • 78649819599 scopus 로고    scopus 로고
    • IGFBP-3 can either inhibit or enhance EGF-mediated growth of breast epithelial cells dependent upon the presence of fibronectin
    • McIntosh J., et al. IGFBP-3 can either inhibit or enhance EGF-mediated growth of breast epithelial cells dependent upon the presence of fibronectin. J. Biol. Chem. 2010, 285(50):38788-38800.
    • (2010) J. Biol. Chem. , vol.285 , Issue.50 , pp. 38788-38800
    • McIntosh, J.1
  • 15
    • 0042031012 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo
    • Butt A.J., et al. Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo. J. Biol. Chem. 2003, 278(32):29676-29685.
    • (2003) J. Biol. Chem. , vol.278 , Issue.32 , pp. 29676-29685
    • Butt, A.J.1
  • 16
    • 0030909663 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein (IGFBP)-3 protease activity secreted by MCF-7 breast cancer cells: inhibition by IGFs does not require IGF-IGFBP interaction
    • Salahifar H., Baxter R.C., Martin J.L. Insulin-like growth factor binding protein (IGFBP)-3 protease activity secreted by MCF-7 breast cancer cells: inhibition by IGFs does not require IGF-IGFBP interaction. Endocrinology 1997, 138(4):1683-1690.
    • (1997) Endocrinology , vol.138 , Issue.4 , pp. 1683-1690
    • Salahifar, H.1    Baxter, R.C.2    Martin, J.L.3
  • 17
    • 0027160175 scopus 로고
    • Insulin-like growth factor binding protein (IGFBP)-3 levels in conditioned media of Hs578T human breast cancer cells are post-transcriptionally regulated
    • Oh Y., et al. Insulin-like growth factor binding protein (IGFBP)-3 levels in conditioned media of Hs578T human breast cancer cells are post-transcriptionally regulated. Growth Regul. 1993, 3(1):84-87.
    • (1993) Growth Regul. , vol.3 , Issue.1 , pp. 84-87
    • Oh, Y.1
  • 18
    • 73149120253 scopus 로고    scopus 로고
    • BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR
    • Carboni J.M., et al. BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR. Mol. Cancer Ther. 2009, 8(12):3341-3349.
    • (2009) Mol. Cancer Ther. , vol.8 , Issue.12 , pp. 3341-3349
    • Carboni, J.M.1
  • 19
    • 0023605087 scopus 로고
    • Partial characterization of somatomedin C-like immunoreactivity secreted by breast cancer cells in vitro
    • Minuto F., et al. Partial characterization of somatomedin C-like immunoreactivity secreted by breast cancer cells in vitro. Mol. Cell. Endocrinol. 1987, 54(2-3):179-184.
    • (1987) Mol. Cell. Endocrinol. , vol.54 , Issue.2-3 , pp. 179-184
    • Minuto, F.1
  • 20
    • 0022525393 scopus 로고
    • Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells
    • Huff K.K., et al. Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells. Cancer Res. 1986, 46(9):4613-4619.
    • (1986) Cancer Res. , vol.46 , Issue.9 , pp. 4613-4619
    • Huff, K.K.1
  • 21
    • 0023903825 scopus 로고
    • Demonstration of insulin-like growth factor (IGF-I and -II) receptors and binding protein in human breast cancer cell lines
    • De Leon D.D., et al. Demonstration of insulin-like growth factor (IGF-I and -II) receptors and binding protein in human breast cancer cell lines. Biochem. Biophys. Res. Commun. 1988, 152(1):398-405.
    • (1988) Biochem. Biophys. Res. Commun. , vol.152 , Issue.1 , pp. 398-405
    • De Leon, D.D.1
  • 22
    • 0025132754 scopus 로고
    • Characterization and hormonal regulation of radioimmunoassayable IGF-I (insulin-like growth factor I) like activity and IGF-binding proteins secreted by human breast cancer cells
    • Ahmed S.R., et al. Characterization and hormonal regulation of radioimmunoassayable IGF-I (insulin-like growth factor I) like activity and IGF-binding proteins secreted by human breast cancer cells. Anticancer Res. 1990, 10(5A):1217-1223.
    • (1990) Anticancer Res. , vol.10 , Issue.5 A , pp. 1217-1223
    • Ahmed, S.R.1
  • 23
    • 0024996154 scopus 로고
    • Insulin-like growth factor binding proteins in human breast cancer cells: relationship to hIGFBP-2 and hIGFBP-3
    • De Leon D.D., et al. Insulin-like growth factor binding proteins in human breast cancer cells: relationship to hIGFBP-2 and hIGFBP-3. J. Clin. Endocrinol. Metab. 1990, 71(2):530-532.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , Issue.2 , pp. 530-532
    • De Leon, D.D.1
  • 24
    • 0023616117 scopus 로고
    • An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture
    • Rohlik Q.T., et al. An antibody to the receptor for insulin-like growth factor I inhibits the growth of MCF-7 cells in tissue culture. Biochem. Biophys. Res. Commun. 1987, 149(1):276-281.
    • (1987) Biochem. Biophys. Res. Commun. , vol.149 , Issue.1 , pp. 276-281
    • Rohlik, Q.T.1
  • 25
    • 0024442071 scopus 로고
    • Insulin-like growth factor-I and its autocrine role in growth of MCF-7 human breast cancer cells in culture
    • Freed K.A., Herington A.C. Insulin-like growth factor-I and its autocrine role in growth of MCF-7 human breast cancer cells in culture. J. Mol. Endocrinol. 1989, 3(3):183-190.
    • (1989) J. Mol. Endocrinol. , vol.3 , Issue.3 , pp. 183-190
    • Freed, K.A.1    Herington, A.C.2
  • 26
    • 0024550730 scopus 로고
    • Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer
    • Yee D., et al. Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol. Endocrinol. 1989, 3(3):509-517.
    • (1989) Mol. Endocrinol. , vol.3 , Issue.3 , pp. 509-517
    • Yee, D.1
  • 27
    • 0024246997 scopus 로고
    • Insulin-like growth factor II mRNA expression in human breast cancer
    • Yee D., et al. Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res. 1988, 48(23):6691-6696.
    • (1988) Cancer Res. , vol.48 , Issue.23 , pp. 6691-6696
    • Yee, D.1
  • 28
    • 0021364464 scopus 로고
    • Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture
    • Furlanetto R.W., DiCarlo J.N. Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture. Cancer Res. 1984, 44(5):2122-2128.
    • (1984) Cancer Res. , vol.44 , Issue.5 , pp. 2122-2128
    • Furlanetto, R.W.1    DiCarlo, J.N.2
  • 29
    • 0023710584 scopus 로고
    • Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17 beta-estradiol
    • Karey K.P., Sirbasku D.A. Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17 beta-estradiol. Cancer Res. 1988, 48(14):4083-4092.
    • (1988) Cancer Res. , vol.48 , Issue.14 , pp. 4083-4092
    • Karey, K.P.1    Sirbasku, D.A.2
  • 30
    • 0022553569 scopus 로고
    • Autocrine and paracrine growth regulation of human breast cancer
    • Lippman M.E., et al. Autocrine and paracrine growth regulation of human breast cancer. J. Steroid Biochem. 1986, 24(1):147-154.
    • (1986) J. Steroid Biochem. , vol.24 , Issue.1 , pp. 147-154
    • Lippman, M.E.1
  • 32
    • 0023710675 scopus 로고
    • Characterization of insulin-like growth factor I (IGF-I) receptors of human breast cancer cells
    • Pollak M.N., et al. Characterization of insulin-like growth factor I (IGF-I) receptors of human breast cancer cells. Biochem. Biophys. Res. Commun. 1988, 154(1):326-331.
    • (1988) Biochem. Biophys. Res. Commun. , vol.154 , Issue.1 , pp. 326-331
    • Pollak, M.N.1
  • 33
    • 0032850369 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death-proliferative and anti-apoptotic effects
    • Gooch J.L., Van Den Berg C.L., Yee D. Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death-proliferative and anti-apoptotic effects. Breast Cancer Res. Treat. 1999, 56(1):1-10.
    • (1999) Breast Cancer Res. Treat. , vol.56 , Issue.1 , pp. 1-10
    • Gooch, J.L.1    Van Den Berg, C.L.2    Yee, D.3
  • 34
    • 0026714984 scopus 로고
    • Interference of the IGF system as a strategy to inhibit breast cancer growth
    • Arteaga C.L. Interference of the IGF system as a strategy to inhibit breast cancer growth. Breast Cancer Res. Treat. 1992, 22(1):101-106.
    • (1992) Breast Cancer Res. Treat. , vol.22 , Issue.1 , pp. 101-106
    • Arteaga, C.L.1
  • 35
    • 0024460381 scopus 로고
    • Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice
    • Arteaga C.L., et al. Blockade of the type I somatomedin receptor inhibits growth of human breast cancer cells in athymic mice. J. Clin. Invest. 1989, 84(5):1418-1423.
    • (1989) J. Clin. Invest. , vol.84 , Issue.5 , pp. 1418-1423
    • Arteaga, C.L.1
  • 36
    • 0024408247 scopus 로고
    • Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor
    • Arteaga C.L., Osborne C.K. Growth inhibition of human breast cancer cells in vitro with an antibody against the type I somatomedin receptor. Cancer Res. 1989, 49(22):6237-6241.
    • (1989) Cancer Res. , vol.49 , Issue.22 , pp. 6237-6241
    • Arteaga, C.L.1    Osborne, C.K.2
  • 37
    • 0025166350 scopus 로고
    • Insulin-like growth factor receptor expression and function in human breast cancer
    • Cullen K.J., et al. Insulin-like growth factor receptor expression and function in human breast cancer. Cancer Res. 1990, 50(1):48-53.
    • (1990) Cancer Res. , vol.50 , Issue.1 , pp. 48-53
    • Cullen, K.J.1
  • 38
    • 0026341456 scopus 로고
    • Growth factor involvement in the multihormonal regulation of MCF-7 breast cancer cell growth in soft agar
    • Manni A., Wright C., Buck H. Growth factor involvement in the multihormonal regulation of MCF-7 breast cancer cell growth in soft agar. Breast Cancer Res. Treat. 1991, 20(1):43-52.
    • (1991) Breast Cancer Res. Treat. , vol.20 , Issue.1 , pp. 43-52
    • Manni, A.1    Wright, C.2    Buck, H.3
  • 39
    • 0029125689 scopus 로고
    • Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid
    • Neuenschwander S., Roberts C.T., LeRoith D. Growth inhibition of MCF-7 breast cancer cells by stable expression of an insulin-like growth factor I receptor antisense ribonucleic acid. Endocrinology 1995, 136(10):4298-4303.
    • (1995) Endocrinology , vol.136 , Issue.10 , pp. 4298-4303
    • Neuenschwander, S.1    Roberts, C.T.2    LeRoith, D.3
  • 40
    • 0026628745 scopus 로고
    • Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells
    • De Leon D.D., et al. Effects of insulin-like growth factors (IGFs) and IGF receptor antibodies on the proliferation of human breast cancer cells. Growth Factors 1992, 6(4):327-336.
    • (1992) Growth Factors , vol.6 , Issue.4 , pp. 327-336
    • De Leon, D.D.1
  • 41
    • 0026710682 scopus 로고
    • Insulin receptor expression and function in human breast cancer cell lines
    • Milazzo G., et al. Insulin receptor expression and function in human breast cancer cell lines. Cancer Res. 1992, 52(14):3924-3930.
    • (1992) Cancer Res. , vol.52 , Issue.14 , pp. 3924-3930
    • Milazzo, G.1
  • 42
    • 0028169507 scopus 로고
    • Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells
    • Yee D., et al. Insulin-like growth factor binding protein 1 expression inhibits insulin-like growth factor I action in MCF-7 breast cancer cells. Cell Growth Differ. 1994, 5(1):73-77.
    • (1994) Cell Growth Differ. , vol.5 , Issue.1 , pp. 73-77
    • Yee, D.1
  • 43
    • 0027942034 scopus 로고
    • The insulin-like growth factor system as a target in breast cancer
    • Yee D. The insulin-like growth factor system as a target in breast cancer. Breast Cancer Res. Treat. 1994, 32(1):85-95.
    • (1994) Breast Cancer Res. Treat. , vol.32 , Issue.1 , pp. 85-95
    • Yee, D.1
  • 44
    • 33645560435 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis
    • Beattie J., et al. Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis. Biochem. J. 2006, 395(1):1-19.
    • (2006) Biochem. J. , vol.395 , Issue.1 , pp. 1-19
    • Beattie, J.1
  • 45
    • 0024556084 scopus 로고
    • Characterization of insulin-like growth factor binding proteins from human breast cancer cells
    • De Leon D.D., et al. Characterization of insulin-like growth factor binding proteins from human breast cancer cells. Mol. Endocrinol. 1989, 3(3):567-574.
    • (1989) Mol. Endocrinol. , vol.3 , Issue.3 , pp. 567-574
    • De Leon, D.D.1
  • 46
    • 0026799489 scopus 로고
    • Regulation of insulin-like growth factor-binding protein (IGFBP) expression by breast cancer cells: use of IGFBP-1 as an inhibitor of insulin-like growth factor action
    • McGuire W.L., et al. Regulation of insulin-like growth factor-binding protein (IGFBP) expression by breast cancer cells: use of IGFBP-1 as an inhibitor of insulin-like growth factor action. J. Natl. Cancer Inst. 1992, 84(17):1336-1341.
    • (1992) J. Natl. Cancer Inst. , vol.84 , Issue.17 , pp. 1336-1341
    • McGuire, W.L.1
  • 47
    • 0026692729 scopus 로고
    • Identification of the insulin-like growth factor binding proteins 5 and 6 (IGFBP-5 and 6) in human breast cancer cells
    • Sheikh M.S., et al. Identification of the insulin-like growth factor binding proteins 5 and 6 (IGFBP-5 and 6) in human breast cancer cells. Biochem. Biophys. Res. Commun. 1992, 183(3):1003-1010.
    • (1992) Biochem. Biophys. Res. Commun. , vol.183 , Issue.3 , pp. 1003-1010
    • Sheikh, M.S.1
  • 48
    • 0029129987 scopus 로고
    • Intracellular levels and secretion of insulin-like-growth-factor-binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium
    • Dubois V., et al. Intracellular levels and secretion of insulin-like-growth-factor-binding proteins in MCF-7/6, MCF-7/AZ and MDA-MB-231 breast cancer cells. Differential modulation by estrogens in serum-free medium. Eur. J. Biochem. 1995, 232(1):47-53.
    • (1995) Eur. J. Biochem. , vol.232 , Issue.1 , pp. 47-53
    • Dubois, V.1
  • 49
    • 0025904844 scopus 로고
    • Identification and regulation of insulin-like growth factor binding proteins produced by hormone-dependent and -independent human breast cancer cell lines
    • Kim I., et al. Identification and regulation of insulin-like growth factor binding proteins produced by hormone-dependent and -independent human breast cancer cell lines. Mol. Cell. Endocrinol. 1991, 78(1-2):71-78.
    • (1991) Mol. Cell. Endocrinol. , vol.78 , Issue.1-2 , pp. 71-78
    • Kim, I.1
  • 50
    • 0030067106 scopus 로고    scopus 로고
    • Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells
    • Huynh H., Yang X., Pollak M. Estradiol and antiestrogens regulate a growth inhibitory insulin-like growth factor binding protein 3 autocrine loop in human breast cancer cells. J. Biol. Chem. 1996, 271(2):1016-1021.
    • (1996) J. Biol. Chem. , vol.271 , Issue.2 , pp. 1016-1021
    • Huynh, H.1    Yang, X.2    Pollak, M.3
  • 51
    • 0028804592 scopus 로고
    • Insulin-like growth factor-binding protein-3 production by MCF-7 breast cancer cells: stimulation by retinoic acid and cyclic adenosine monophosphate and differential effects of estradiol
    • Martin J.L., et al. Insulin-like growth factor-binding protein-3 production by MCF-7 breast cancer cells: stimulation by retinoic acid and cyclic adenosine monophosphate and differential effects of estradiol. Endocrinology 1995, 136(3):1219-1226.
    • (1995) Endocrinology , vol.136 , Issue.3 , pp. 1219-1226
    • Martin, J.L.1
  • 52
    • 0027496222 scopus 로고
    • Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media
    • Pratt S.E., Pollak M.N. Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media. Cancer Res. 1993, 53(21):5193-5198.
    • (1993) Cancer Res. , vol.53 , Issue.21 , pp. 5193-5198
    • Pratt, S.E.1    Pollak, M.N.2
  • 53
    • 0026726478 scopus 로고
    • Insulin-like growth factor-I (IGF-I) and retinoic acid modulation of IGF-binding proteins (IGFBPs): IGFBP-2, -3, and -4 gene expression and protein secretion in a breast cancer cell line
    • Adamo M.L., et al. Insulin-like growth factor-I (IGF-I) and retinoic acid modulation of IGF-binding proteins (IGFBPs): IGFBP-2, -3, and -4 gene expression and protein secretion in a breast cancer cell line. Endocrinology 1992, 131(4):1858-1866.
    • (1992) Endocrinology , vol.131 , Issue.4 , pp. 1858-1866
    • Adamo, M.L.1
  • 54
    • 42649135121 scopus 로고    scopus 로고
    • Role of insulin-like growth factor binding protein-3 in human umbilical vein endothelial cell senescence
    • Muck C., et al. Role of insulin-like growth factor binding protein-3 in human umbilical vein endothelial cell senescence. Rejuvenation Res. 2008, 11(2):449-453.
    • (2008) Rejuvenation Res. , vol.11 , Issue.2 , pp. 449-453
    • Muck, C.1
  • 55
    • 2442697703 scopus 로고    scopus 로고
    • IGFBP-3, a marker of cellular senescence, is overexpressed in human papillomavirus-immortalized cervical cells and enhances IGF-1-induced mitogenesis
    • Baege A.C., Disbrow G.L., Schlegel R. IGFBP-3, a marker of cellular senescence, is overexpressed in human papillomavirus-immortalized cervical cells and enhances IGF-1-induced mitogenesis. J. Virol. 2004, 78(11):5720-5727.
    • (2004) J. Virol. , vol.78 , Issue.11 , pp. 5720-5727
    • Baege, A.C.1    Disbrow, G.L.2    Schlegel, R.3
  • 56
    • 0027194384 scopus 로고
    • Accumulation of insulin-like growth factor binding protein-3 in conditioned medium of human fibroblasts increases with chronologic age of donor and senescence in vitro
    • Goldstein S., Moerman E.J., Baxter R.C. Accumulation of insulin-like growth factor binding protein-3 in conditioned medium of human fibroblasts increases with chronologic age of donor and senescence in vitro. J. Cell. Physiol. 1993, 156(2):294-302.
    • (1993) J. Cell. Physiol. , vol.156 , Issue.2 , pp. 294-302
    • Goldstein, S.1    Moerman, E.J.2    Baxter, R.C.3
  • 57
    • 0028807561 scopus 로고
    • Insulin-like growth factors modulate the growth inhibitory effects of retinoic acid on MCF-7 breast cancer cells
    • Bentel J.M., et al. Insulin-like growth factors modulate the growth inhibitory effects of retinoic acid on MCF-7 breast cancer cells. J. Cell. Physiol. 1995, 165(1):212-221.
    • (1995) J. Cell. Physiol. , vol.165 , Issue.1 , pp. 212-221
    • Bentel, J.M.1
  • 58
    • 0027239935 scopus 로고
    • Retinoic acid and estrogen modulation of insulin-like growth factor binding protein-4 gene expression and the estrogen receptor status of human breast carcinoma cells
    • Sheikh M.S., et al. Retinoic acid and estrogen modulation of insulin-like growth factor binding protein-4 gene expression and the estrogen receptor status of human breast carcinoma cells. Biochem. Biophys. Res. Commun. 1993, 193(3):1232-1238.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , Issue.3 , pp. 1232-1238
    • Sheikh, M.S.1
  • 59
    • 0026498259 scopus 로고
    • Insulin-like growth factor binding protein-5 gene expression is differentially regulated at a post-transcriptional level in retinoic acid-sensitive and resistant MCF-7 human breast carcinoma cells
    • Sheikh M.S., et al. Insulin-like growth factor binding protein-5 gene expression is differentially regulated at a post-transcriptional level in retinoic acid-sensitive and resistant MCF-7 human breast carcinoma cells. Biochem. Biophys. Res. Commun. 1992, 188(3):1122-1130.
    • (1992) Biochem. Biophys. Res. Commun. , vol.188 , Issue.3 , pp. 1122-1130
    • Sheikh, M.S.1
  • 60
    • 0025971180 scopus 로고
    • Retinoid modulation of insulin-like growth factor-binding proteins and inhibition of breast carcinoma proliferation
    • Fontana J.A., et al. Retinoid modulation of insulin-like growth factor-binding proteins and inhibition of breast carcinoma proliferation. Endocrinology 1991, 128(2):1115-1122.
    • (1991) Endocrinology , vol.128 , Issue.2 , pp. 1115-1122
    • Fontana, J.A.1
  • 61
    • 0037040971 scopus 로고    scopus 로고
    • Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk
    • Klotz D.M., et al. Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk. J. Biol. Chem. 2002, 277(10):8531-8537.
    • (2002) J. Biol. Chem. , vol.277 , Issue.10 , pp. 8531-8537
    • Klotz, D.M.1
  • 62
    • 0029859008 scopus 로고    scopus 로고
    • Estradiol stimulates tyrosine phosphorylation of the insulin-like growth factor-1 receptor and insulin receptor substrate-1 in the uterus
    • Richards R.G., et al. Estradiol stimulates tyrosine phosphorylation of the insulin-like growth factor-1 receptor and insulin receptor substrate-1 in the uterus. Proc. Natl. Acad. Sci. U. S. A. 1996, 93(21):12002-12007.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.21 , pp. 12002-12007
    • Richards, R.G.1
  • 63
    • 84857915302 scopus 로고    scopus 로고
    • Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth
    • Casa A.J., et al. Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth. Breast Cancer Res. Treat. 2012, 132(1):61-73.
    • (2012) Breast Cancer Res. Treat. , vol.132 , Issue.1 , pp. 61-73
    • Casa, A.J.1
  • 64
    • 0021958425 scopus 로고
    • Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice
    • Osborne C.K., Hobbs K., Clark G.M. Effect of estrogens and antiestrogens on growth of human breast cancer cells in athymic nude mice. Cancer Res. 1985, 45(2):584-590.
    • (1985) Cancer Res. , vol.45 , Issue.2 , pp. 584-590
    • Osborne, C.K.1    Hobbs, K.2    Clark, G.M.3
  • 65
    • 67749144226 scopus 로고    scopus 로고
    • Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer
    • Jiralerspong S., et al. Metformin and pathologic complete responses to neoadjuvant chemotherapy in diabetic patients with breast cancer. J. Clin. Oncol. 2009, 27(20):3297-3302.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.20 , pp. 3297-3302
    • Jiralerspong, S.1
  • 66
    • 67749134053 scopus 로고    scopus 로고
    • Metformin in breast cancer: time for action
    • Goodwin P.J., Ligibel J.A., Stambolic V. Metformin in breast cancer: time for action. J. Clin. Oncol. 2009, 27(20):3271-3273.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.20 , pp. 3271-3273
    • Goodwin, P.J.1    Ligibel, J.A.2    Stambolic, V.3
  • 67
    • 80053932300 scopus 로고    scopus 로고
    • Randomized trial of tamoxifen versus combined tamoxifen and octreotide LAR therapy in the adjuvant treatment of early-stage breast cancer in postmenopausal women: NCIC CTG MA.14
    • Pritchard K.I., et al. Randomized trial of tamoxifen versus combined tamoxifen and octreotide LAR therapy in the adjuvant treatment of early-stage breast cancer in postmenopausal women: NCIC CTG MA.14. J. Clin. Oncol. 2011, 29(29):3869-3876.
    • (2011) J. Clin. Oncol. , vol.29 , Issue.29 , pp. 3869-3876
    • Pritchard, K.I.1
  • 68
    • 0028799676 scopus 로고
    • Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid
    • Ruan W., et al. Estradiol enhances the stimulatory effect of insulin-like growth factor-I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid. Endocrinology 1995, 136(3):1296-1302.
    • (1995) Endocrinology , vol.136 , Issue.3 , pp. 1296-1302
    • Ruan, W.1
  • 69
    • 63049112424 scopus 로고    scopus 로고
    • Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites
    • Atsriku C., et al. Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites. Mol. Cell. Proteomics 2009, 8(3):467-480.
    • (2009) Mol. Cell. Proteomics , vol.8 , Issue.3 , pp. 467-480
    • Atsriku, C.1
  • 70
    • 59249095830 scopus 로고    scopus 로고
    • IGF signaling pathway as a selective target of familial breast cancer therapy
    • Shukla V., et al. IGF signaling pathway as a selective target of familial breast cancer therapy. Curr. Mol. Med. 2008, 8(8):727-740.
    • (2008) Curr. Mol. Med. , vol.8 , Issue.8 , pp. 727-740
    • Shukla, V.1
  • 71
    • 57149139395 scopus 로고    scopus 로고
    • Regulation of breast cancer metastasis by IGF signaling
    • Sachdev D. Regulation of breast cancer metastasis by IGF signaling. J. Mammary Gland Biol. Neoplasia 2008, 13(4):431-441.
    • (2008) J. Mammary Gland Biol. Neoplasia , vol.13 , Issue.4 , pp. 431-441
    • Sachdev, D.1
  • 72
    • 80155131176 scopus 로고    scopus 로고
    • A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer
    • Fox E.M., et al. A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. Cancer Res. 2011, 71(21):6773-6784.
    • (2011) Cancer Res. , vol.71 , Issue.21 , pp. 6773-6784
    • Fox, E.M.1
  • 73
    • 10944260245 scopus 로고    scopus 로고
    • Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1
    • Mawson A., et al. Estrogen and insulin/IGF-1 cooperatively stimulate cell cycle progression in MCF-7 breast cancer cells through differential regulation of c-Myc and cyclin D1. Mol. Cell. Endocrinol. 2005, 229(1-2):161-173.
    • (2005) Mol. Cell. Endocrinol. , vol.229 , Issue.1-2 , pp. 161-173
    • Mawson, A.1
  • 74
    • 0034526749 scopus 로고    scopus 로고
    • A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I
    • Martin M.B., et al. A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. Endocrinology 2000, 141(12):4503-4511.
    • (2000) Endocrinology , vol.141 , Issue.12 , pp. 4503-4511
    • Martin, M.B.1
  • 75
    • 1242341918 scopus 로고    scopus 로고
    • The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane
    • Song R.X., et al. The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane. Proc. Natl. Acad. Sci. U. S. A. 2004, 101(7):2076-2081.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , Issue.7 , pp. 2076-2081
    • Song, R.X.1
  • 76
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato S., et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995, 270(5241):1491-1494.
    • (1995) Science , vol.270 , Issue.5241 , pp. 1491-1494
    • Kato, S.1
  • 77
    • 0034727094 scopus 로고    scopus 로고
    • Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase
    • Simoncini T., et al. Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase. Nature 2000, 407(6803):538-541.
    • (2000) Nature , vol.407 , Issue.6803 , pp. 538-541
    • Simoncini, T.1
  • 78
    • 0037663541 scopus 로고    scopus 로고
    • Estrogen receptor-alpha regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells
    • Morelli C., et al. Estrogen receptor-alpha regulates the degradation of insulin receptor substrates 1 and 2 in breast cancer cells. Oncogene 2003, 22(26):4007-4016.
    • (2003) Oncogene , vol.22 , Issue.26 , pp. 4007-4016
    • Morelli, C.1
  • 79
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation
    • Song R.X., et al. Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation. Mol. Endocrinol. 2002, 16(1):116-127.
    • (2002) Mol. Endocrinol. , vol.16 , Issue.1 , pp. 116-127
    • Song, R.X.1
  • 80
    • 17944375553 scopus 로고    scopus 로고
    • PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells
    • Castoria G., et al. PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells. EMBO J. 2001, 20(21):6050-6059.
    • (2001) EMBO J. , vol.20 , Issue.21 , pp. 6050-6059
    • Castoria, G.1
  • 81
    • 0034674065 scopus 로고    scopus 로고
    • Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway
    • Kahlert S., et al. Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway. J. Biol. Chem. 2000, 275(24):18447-18453.
    • (2000) J. Biol. Chem. , vol.275 , Issue.24 , pp. 18447-18453
    • Kahlert, S.1
  • 82
    • 25644447454 scopus 로고    scopus 로고
    • Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells
    • Lee Y.R., et al. Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells. Biochem. Biophys. Res. Commun. 2005, 336(4):1221-1226.
    • (2005) Biochem. Biophys. Res. Commun. , vol.336 , Issue.4 , pp. 1221-1226
    • Lee, Y.R.1
  • 83
    • 35748930595 scopus 로고    scopus 로고
    • The estrogen receptor alpha:insulin receptor substrate 1 complex in breast cancer: structure-function relationships
    • Sisci D., et al. The estrogen receptor alpha:insulin receptor substrate 1 complex in breast cancer: structure-function relationships. Ann. Oncol. 2007, 18(Suppl. 6):vi81-vi85.
    • (2007) Ann. Oncol. , vol.18 , Issue.SUPPL. 6
    • Sisci, D.1
  • 84
    • 79952135852 scopus 로고    scopus 로고
    • The IGF pathway regulates ERalpha through a S6K1-dependent mechanism in breast cancer cells
    • Becker M.A., et al. The IGF pathway regulates ERalpha through a S6K1-dependent mechanism in breast cancer cells. Mol. Endocrinol. 2011, 25(3):516-528.
    • (2011) Mol. Endocrinol. , vol.25 , Issue.3 , pp. 516-528
    • Becker, M.A.1
  • 85
    • 0033636597 scopus 로고    scopus 로고
    • Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7
    • Chen D., et al. Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7. Mol. Cell 2000, 6(1):127-137.
    • (2000) Mol. Cell , vol.6 , Issue.1 , pp. 127-137
    • Chen, D.1
  • 86
    • 0032557452 scopus 로고    scopus 로고
    • Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase
    • Joel P.B., Traish A.M., Lannigan D.A. Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase. J. Biol. Chem. 1998, 273(21):13317-13323.
    • (1998) J. Biol. Chem. , vol.273 , Issue.21 , pp. 13317-13323
    • Joel, P.B.1    Traish, A.M.2    Lannigan, D.A.3
  • 87
    • 25444468111 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity
    • Medunjanin S., et al. Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity. J. Biol. Chem. 2005, 280(38):33006-33014.
    • (2005) J. Biol. Chem. , vol.280 , Issue.38 , pp. 33006-33014
    • Medunjanin, S.1
  • 88
    • 84855417073 scopus 로고    scopus 로고
    • Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice
    • Tian J., et al. Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice. J. Clin. Invest. 2012, 122(1):192-204.
    • (2012) J. Clin. Invest. , vol.122 , Issue.1 , pp. 192-204
    • Tian, J.1
  • 89
    • 77951557127 scopus 로고    scopus 로고
    • Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity
    • Barone I., et al. Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivity. Oncogene 2010, 29(16):2404-2414.
    • (2010) Oncogene , vol.29 , Issue.16 , pp. 2404-2414
    • Barone, I.1
  • 90
    • 10844286471 scopus 로고    scopus 로고
    • Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity
    • Cui Y., et al. Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity. Cancer Res. 2004, 64(24):9199-9208.
    • (2004) Cancer Res. , vol.64 , Issue.24 , pp. 9199-9208
    • Cui, Y.1
  • 91
    • 62949213226 scopus 로고    scopus 로고
    • The relevance of phosphorylated forms of estrogen receptor in human breast cancer in vivo
    • Murphy L.C., et al. The relevance of phosphorylated forms of estrogen receptor in human breast cancer in vivo. J. Steroid Biochem. Mol. Biol. 2009, 114(1-2):90-95.
    • (2009) J. Steroid Biochem. Mol. Biol. , vol.114 , Issue.1-2 , pp. 90-95
    • Murphy, L.C.1
  • 92
    • 79251518293 scopus 로고    scopus 로고
    • Clinical significance of estrogen receptor phosphorylation
    • Murphy L.C., Seekallu S.V., Watson P.H. Clinical significance of estrogen receptor phosphorylation. Endocr. Relat. Cancer 2011, 18(1):R1-R14.
    • (2011) Endocr. Relat. Cancer , vol.18 , Issue.1
    • Murphy, L.C.1    Seekallu, S.V.2    Watson, P.H.3
  • 93
    • 84876753114 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor
    • Foulstone E.J., et al. Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. Endocrinology 2013, 154(5):1780-1793.
    • (2013) Endocrinology , vol.154 , Issue.5 , pp. 1780-1793
    • Foulstone, E.J.1
  • 94
    • 84876306520 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-alpha activation in breast cancer cells in an IGF-independent manner
    • Hermani A., et al. Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-alpha activation in breast cancer cells in an IGF-independent manner. Cell. Signal. 2013, 25(6):1395-1402.
    • (2013) Cell. Signal. , vol.25 , Issue.6 , pp. 1395-1402
    • Hermani, A.1
  • 95
    • 0029959858 scopus 로고    scopus 로고
    • A role for insulin-like growth factor binding protein 5 in the antiproliferative action of the antiestrogen ICI 182780
    • Huynh H., Yang X.F., Pollak M. A role for insulin-like growth factor binding protein 5 in the antiproliferative action of the antiestrogen ICI 182780. Cell Growth Differ. 1996, 7(11):1501-1506.
    • (1996) Cell Growth Differ. , vol.7 , Issue.11 , pp. 1501-1506
    • Huynh, H.1    Yang, X.F.2    Pollak, M.3
  • 96
    • 54849437262 scopus 로고    scopus 로고
    • Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity
    • Tharakan R., et al. Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity. Mol. Cell. Endocrinol. 2008, 295(1-2):70-78.
    • (2008) Mol. Cell. Endocrinol. , vol.295 , Issue.1-2 , pp. 70-78
    • Tharakan, R.1
  • 97
    • 42549131382 scopus 로고    scopus 로고
    • Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-alpha activity
    • Thomas R.S., et al. Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-alpha activity. J. Mol. Endocrinol. 2008, 40(4):173-184.
    • (2008) J. Mol. Endocrinol. , vol.40 , Issue.4 , pp. 173-184
    • Thomas, R.S.1
  • 98
    • 25844468319 scopus 로고    scopus 로고
    • Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer
    • Gee J.M., et al. Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. Endocr. Relat. Cancer 2005, 12(Suppl. 1):S99-S111.
    • (2005) Endocr. Relat. Cancer , vol.12 , Issue.SUPPL. 1
    • Gee, J.M.1
  • 99
    • 4444324186 scopus 로고    scopus 로고
    • Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen
    • Murphy L.C., et al. Phospho-serine-118 estrogen receptor-alpha expression is associated with better disease outcome in women treated with tamoxifen. Clin. Cancer Res. 2004, 10(17):5902-5906.
    • (2004) Clin. Cancer Res. , vol.10 , Issue.17 , pp. 5902-5906
    • Murphy, L.C.1
  • 100
    • 84877690804 scopus 로고    scopus 로고
    • Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells
    • Tsonis A.I., et al. Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells. FEBS J. 2013, 280(10):2248-2259.
    • (2013) FEBS J. , vol.280 , Issue.10 , pp. 2248-2259
    • Tsonis, A.I.1
  • 101
    • 84870884093 scopus 로고    scopus 로고
    • Role of estrogen receptor-alpha (ESR1) and the type 1 insulin-like growth factor receptor (IGFR1) in estradiol-stimulated proliferation of cultured bovine satellite cells
    • Kamanga-Sollo E., et al. Role of estrogen receptor-alpha (ESR1) and the type 1 insulin-like growth factor receptor (IGFR1) in estradiol-stimulated proliferation of cultured bovine satellite cells. Domest. Anim. Endocrinol. 2013, 44(1):36-45.
    • (2013) Domest. Anim. Endocrinol. , vol.44 , Issue.1 , pp. 36-45
    • Kamanga-Sollo, E.1
  • 102
    • 34548768315 scopus 로고    scopus 로고
    • 17beta-Estradiol up-regulates the insulin-like growth factor receptor through a nongenotropic pathway in prostate cancer cells
    • Pandini G., et al. 17beta-Estradiol up-regulates the insulin-like growth factor receptor through a nongenotropic pathway in prostate cancer cells. Cancer Res. 2007, 67(18):8932-8941.
    • (2007) Cancer Res. , vol.67 , Issue.18 , pp. 8932-8941
    • Pandini, G.1
  • 103
    • 78650968836 scopus 로고    scopus 로고
    • Interactions between IGF-I, estrogen receptor-alpha (ERalpha), and ERbeta in regulating growth/apoptosis of MCF-7 human breast cancer cells
    • Mendoza R.A., et al. Interactions between IGF-I, estrogen receptor-alpha (ERalpha), and ERbeta in regulating growth/apoptosis of MCF-7 human breast cancer cells. J. Endocrinol. 2011, 208(1):1-9.
    • (2011) J. Endocrinol. , vol.208 , Issue.1 , pp. 1-9
    • Mendoza, R.A.1
  • 104
    • 38849141014 scopus 로고    scopus 로고
    • Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor beta
    • Picard N., et al. Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor beta. Mol. Endocrinol. 2008, 22(2):317-330.
    • (2008) Mol. Endocrinol. , vol.22 , Issue.2 , pp. 317-330
    • Picard, N.1
  • 105
    • 0033120030 scopus 로고    scopus 로고
    • Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1
    • Tremblay A., et al. Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1. Mol. Cell 1999, 3(4):513-519.
    • (1999) Mol. Cell , vol.3 , Issue.4 , pp. 513-519
    • Tremblay, A.1
  • 106
    • 0037294686 scopus 로고    scopus 로고
    • Putative functional characteristics of human estrogen receptor-beta isoforms
    • Peng B., et al. Putative functional characteristics of human estrogen receptor-beta isoforms. J. Mol. Endocrinol. 2003, 30(1):13-29.
    • (2003) J. Mol. Endocrinol. , vol.30 , Issue.1 , pp. 13-29
    • Peng, B.1
  • 107
    • 0031282001 scopus 로고    scopus 로고
    • Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer
    • Carmeci C., et al. Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer. Genomics 1997, 45(3):607-617.
    • (1997) Genomics , vol.45 , Issue.3 , pp. 607-617
    • Carmeci, C.1
  • 108
    • 43549095238 scopus 로고    scopus 로고
    • Estrogen signaling through the transmembrane G protein-coupled receptor GPR30
    • Prossnitz E.R., et al. Estrogen signaling through the transmembrane G protein-coupled receptor GPR30. Annu. Rev. Physiol. 2008, 70:165-190.
    • (2008) Annu. Rev. Physiol. , vol.70 , pp. 165-190
    • Prossnitz, E.R.1
  • 109
    • 84873743039 scopus 로고    scopus 로고
    • Insulin-like growth factor-I regulates GPER expression and function in cancer cells
    • De Marco P., et al. Insulin-like growth factor-I regulates GPER expression and function in cancer cells. Oncogene 2013, 32(6):678-688.
    • (2013) Oncogene , vol.32 , Issue.6 , pp. 678-688
    • De Marco, P.1
  • 110
    • 28844458917 scopus 로고    scopus 로고
    • Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells
    • Akekawatchai C., et al. Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells. J. Biol. Chem. 2005, 280(48):39701-39708.
    • (2005) J. Biol. Chem. , vol.280 , Issue.48 , pp. 39701-39708
    • Akekawatchai, C.1
  • 111
    • 0026038047 scopus 로고
    • The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer
    • Yee D., et al. The insulin-like growth factors, their receptors, and their binding proteins in human breast cancer. Cancer Treat. Res. 1991, 53:93-106.
    • (1991) Cancer Treat. Res. , vol.53 , pp. 93-106
    • Yee, D.1
  • 112
    • 82355188243 scopus 로고    scopus 로고
    • Minireview: putting physiology back into estrogens' mechanism of action
    • Koos R.D. Minireview: putting physiology back into estrogens' mechanism of action. Endocrinology 2011, 152(12):4481-4488.
    • (2011) Endocrinology , vol.152 , Issue.12 , pp. 4481-4488
    • Koos, R.D.1
  • 113
    • 0025635904 scopus 로고
    • Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells
    • Stewart A.J., et al. Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. J. Biol. Chem. 1990, 265(34):21172-21178.
    • (1990) J. Biol. Chem. , vol.265 , Issue.34 , pp. 21172-21178
    • Stewart, A.J.1
  • 114
    • 0031014164 scopus 로고    scopus 로고
    • Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone
    • Clarke R.B., Howell A., Anderson E. Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone. Br. J. Cancer 1997, 75(2):251-257.
    • (1997) Br. J. Cancer , vol.75 , Issue.2 , pp. 251-257
    • Clarke, R.B.1    Howell, A.2    Anderson, E.3
  • 115
    • 0030458110 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780
    • Huynh H., et al. Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780. Clin. Cancer Res. 1996, 2(12):2037-2042.
    • (1996) Clin. Cancer Res. , vol.2 , Issue.12 , pp. 2037-2042
    • Huynh, H.1
  • 116
    • 0028007428 scopus 로고
    • Role of insulin-like growth factors in steroid modulated proliferation
    • Westley B.R., May F.E. Role of insulin-like growth factors in steroid modulated proliferation. J. Steroid Biochem. Mol. Biol. 1994, 51(1-2):1-9.
    • (1994) J. Steroid Biochem. Mol. Biol. , vol.51 , Issue.1-2 , pp. 1-9
    • Westley, B.R.1    May, F.E.2
  • 117
    • 33846846385 scopus 로고    scopus 로고
    • Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1
    • Maor S., et al. Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. J. Endocrinol. 2006, 191(3):605-612.
    • (2006) J. Endocrinol. , vol.191 , Issue.3 , pp. 605-612
    • Maor, S.1
  • 118
    • 70349747010 scopus 로고    scopus 로고
    • Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells
    • Genua M., et al. Role of cyclic AMP response element-binding protein in insulin-like growth factor-i receptor up-regulation by sex steroids in prostate cancer cells. Cancer Res. 2009, 69(18):7270-7277.
    • (2009) Cancer Res. , vol.69 , Issue.18 , pp. 7270-7277
    • Genua, M.1
  • 119
    • 0026513369 scopus 로고
    • Oestradiol treatment increases the sensitivity of MCF-7 cells for the growth stimulatory effect of IGF-I
    • Thorsen T., et al. Oestradiol treatment increases the sensitivity of MCF-7 cells for the growth stimulatory effect of IGF-I. J. Steroid Biochem. Mol. Biol. 1992, 41(3-8):537-540.
    • (1992) J. Steroid Biochem. Mol. Biol. , vol.41 , Issue.3-8 , pp. 537-540
    • Thorsen, T.1
  • 120
    • 0026001074 scopus 로고
    • Estradiol down-regulates the mannose-6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin-D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes
    • Mathieu M., et al. Estradiol down-regulates the mannose-6-phosphate/insulin-like growth factor-II receptor gene and induces cathepsin-D in breast cancer cells: a receptor saturation mechanism to increase the secretion of lysosomal proenzymes. Mol. Endocrinol. 1991, 5(6):815-822.
    • (1991) Mol. Endocrinol. , vol.5 , Issue.6 , pp. 815-822
    • Mathieu, M.1
  • 121
    • 0024369203 scopus 로고
    • Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor
    • Osborne C.K., et al. Insulin-like growth factor-II (IGF-II): a potential autocrine/paracrine growth factor for human breast cancer acting via the IGF-I receptor. Mol. Endocrinol. 1989, 3(11):1701-1709.
    • (1989) Mol. Endocrinol. , vol.3 , Issue.11 , pp. 1701-1709
    • Osborne, C.K.1
  • 122
    • 34547095246 scopus 로고    scopus 로고
    • Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells
    • Song R.X., et al. Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein kinase in MCF-7 breast cancer cells. Endocrinology 2007, 148(8):4091-4101.
    • (2007) Endocrinology , vol.148 , Issue.8 , pp. 4091-4101
    • Song, R.X.1
  • 123
    • 63649117164 scopus 로고    scopus 로고
    • Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells
    • Santen R.J., et al. Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells. Steroids 2009, 74(7):586-594.
    • (2009) Steroids , vol.74 , Issue.7 , pp. 586-594
    • Santen, R.J.1
  • 124
    • 77950346929 scopus 로고    scopus 로고
    • Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells
    • Song R.X., et al. Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells. J. Steroid Biochem. Mol. Biol. 2010, 118(4-5):219-230.
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.118 , Issue.4-5 , pp. 219-230
    • Song, R.X.1
  • 125
    • 34047234959 scopus 로고    scopus 로고
    • Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis
    • Gibson S.L., Ma Z., Shaw L.M. Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis. Cell Cycle 2007, 6(6):631-637.
    • (2007) Cell Cycle , vol.6 , Issue.6 , pp. 631-637
    • Gibson, S.L.1    Ma, Z.2    Shaw, L.M.3
  • 126
    • 33244479616 scopus 로고    scopus 로고
    • Evidence that the mouse insulin receptor substrate-1 belongs to the gene family on which the promoter is activated by estrogen receptor alpha through its interaction with Sp1
    • Panno M.L., et al. Evidence that the mouse insulin receptor substrate-1 belongs to the gene family on which the promoter is activated by estrogen receptor alpha through its interaction with Sp1. J. Mol. Endocrinol. 2006, 36(1):91-105.
    • (2006) J. Mol. Endocrinol. , vol.36 , Issue.1 , pp. 91-105
    • Panno, M.L.1
  • 127
    • 0033305004 scopus 로고    scopus 로고
    • Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
    • Lee A.V., et al. Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol. Endocrinol. 1999, 13(5):787-796.
    • (1999) Mol. Endocrinol. , vol.13 , Issue.5 , pp. 787-796
    • Lee, A.V.1
  • 128
    • 84867679163 scopus 로고    scopus 로고
    • Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells
    • Gaben A.M., et al. Ligand-free estrogen receptor activity complements IGF1R to induce the proliferation of the MCF-7 breast cancer cells. BMC Cancer 2012, 12:291.
    • (2012) BMC Cancer , vol.12 , pp. 291
    • Gaben, A.M.1
  • 129
    • 0026784870 scopus 로고
    • The insulin-like growth factor binding proteins (IGFBPs) in human breast cancer
    • Figueroa J.A., Yee D. The insulin-like growth factor binding proteins (IGFBPs) in human breast cancer. Breast Cancer Res. Treat. 1992, 22(1):81-90.
    • (1992) Breast Cancer Res. Treat. , vol.22 , Issue.1 , pp. 81-90
    • Figueroa, J.A.1    Yee, D.2
  • 130
    • 0027762610 scopus 로고
    • Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells
    • Wiseman L.R., et al. Type I IGF receptor and acquired tamoxifen resistance in oestrogen-responsive human breast cancer cells. Eur. J. Cancer 1993, 29A(16):2256-2264.
    • (1993) Eur. J. Cancer , vol.29 A , Issue.16 , pp. 2256-2264
    • Wiseman, L.R.1
  • 131
    • 26844487041 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor
    • Knowlden J.M., et al. Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. Endocrinology 2005, 146(11):4609-4618.
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4609-4618
    • Knowlden, J.M.1
  • 132
    • 33748068094 scopus 로고    scopus 로고
    • Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer
    • Massarweh S., et al. Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer. Cancer Res. 2006, 66(16):8266-8273.
    • (2006) Cancer Res. , vol.66 , Issue.16 , pp. 8266-8273
    • Massarweh, S.1
  • 133
    • 0033001742 scopus 로고    scopus 로고
    • Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line
    • Parisot J.P., et al. Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line. Br. J. Cancer 1999, 79(5-6):693-700.
    • (1999) Br. J. Cancer , vol.79 , Issue.5-6 , pp. 693-700
    • Parisot, J.P.1
  • 134
    • 0031915780 scopus 로고    scopus 로고
    • The anti-proliferative effect of suramin towards tamoxifen-sensitive and resistant human breast cancer cell lines in relation to expression of receptors for epidermal growth factor and insulin-like growth factor-I: growth stimulation in the presence of tamoxifen
    • Boylan M., van den Berg H.W., Lynch M. The anti-proliferative effect of suramin towards tamoxifen-sensitive and resistant human breast cancer cell lines in relation to expression of receptors for epidermal growth factor and insulin-like growth factor-I: growth stimulation in the presence of tamoxifen. Ann. Oncol. 1998, 9(2):205-211.
    • (1998) Ann. Oncol. , vol.9 , Issue.2 , pp. 205-211
    • Boylan, M.1    van den Berg, H.W.2    Lynch, M.3
  • 135
    • 69449097339 scopus 로고    scopus 로고
    • Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions
    • Gualberto A., Pollak M. Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene 2009, 28(34):3009-3021.
    • (2009) Oncogene , vol.28 , Issue.34 , pp. 3009-3021
    • Gualberto, A.1    Pollak, M.2
  • 136
    • 0030041324 scopus 로고    scopus 로고
    • Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: the effect of steroid hormones on insulin-like growth factor I receptor expression
    • van den Berg H.W., et al. Expression of receptors for epidermal growth factor and insulin-like growth factor I by ZR-75-1 human breast cancer cell variants is inversely related: the effect of steroid hormones on insulin-like growth factor I receptor expression. Br. J. Cancer 1996, 73(4):477-481.
    • (1996) Br. J. Cancer , vol.73 , Issue.4 , pp. 477-481
    • van den Berg, H.W.1
  • 137
    • 33847023585 scopus 로고    scopus 로고
    • Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells
    • Fan P., et al. Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. Cancer Res. 2007, 67(3):1352-1360.
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 1352-1360
    • Fan, P.1
  • 138
    • 84875257995 scopus 로고    scopus 로고
    • Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial
    • Robertson J.F., et al. Ganitumab with either exemestane or fulvestrant for postmenopausal women with advanced, hormone-receptor-positive breast cancer: a randomised, controlled, double-blind, phase 2 trial. Lancet Oncol. 2013, 14(3):228-235.
    • (2013) Lancet Oncol. , vol.14 , Issue.3 , pp. 228-235
    • Robertson, J.F.1
  • 139
    • 84863900275 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor inhibitors: baby or the bathwater?
    • Yee D. Insulin-like growth factor receptor inhibitors: baby or the bathwater?. J. Natl. Cancer Inst. 2012, 104(13):975-981.
    • (2012) J. Natl. Cancer Inst. , vol.104 , Issue.13 , pp. 975-981
    • Yee, D.1
  • 140
    • 84863584930 scopus 로고    scopus 로고
    • Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment
    • Fagan D.H., et al. Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment. Cancer Res. 2012, 72(13):3372-3380.
    • (2012) Cancer Res. , vol.72 , Issue.13 , pp. 3372-3380
    • Fagan, D.H.1
  • 141
    • 84860506226 scopus 로고    scopus 로고
    • Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors
    • Naing A., et al. Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors. Clin. Cancer Res. 2012, 18(9):2625-2631.
    • (2012) Clin. Cancer Res. , vol.18 , Issue.9 , pp. 2625-2631
    • Naing, A.1
  • 142
    • 77649268890 scopus 로고    scopus 로고
    • Inhibitors of the PI3K/Akt/mTOR pathway: new hope for breast cancer patients
    • Ghayad S.E., Cohen P.A. Inhibitors of the PI3K/Akt/mTOR pathway: new hope for breast cancer patients. Recent Pat. Anticancer Drug Discov. 2010, 5(1):29-57.
    • (2010) Recent Pat. Anticancer Drug Discov. , vol.5 , Issue.1 , pp. 29-57
    • Ghayad, S.E.1    Cohen, P.A.2
  • 143
    • 0030067040 scopus 로고    scopus 로고
    • Changes in insulin-like growth factor-I receptor expression and binding protein secretion associated with tamoxifen resistance and estrogen independence in human breast cancer cells in vitro
    • McCotter D., et al. Changes in insulin-like growth factor-I receptor expression and binding protein secretion associated with tamoxifen resistance and estrogen independence in human breast cancer cells in vitro. Cancer Lett. 1996, 99(2):239-245.
    • (1996) Cancer Lett. , vol.99 , Issue.2 , pp. 239-245
    • McCotter, D.1
  • 144
    • 0032960156 scopus 로고    scopus 로고
    • Changes in the secretion of insulin-like growth factor binding proteins -2 and -4 associated with the development of tamoxifen resistance and estrogen independence in human breast cancer cell lines
    • Maxwell P., van den Berg H.W. Changes in the secretion of insulin-like growth factor binding proteins -2 and -4 associated with the development of tamoxifen resistance and estrogen independence in human breast cancer cell lines. Cancer Lett. 1999, 139(2):121-127.
    • (1999) Cancer Lett. , vol.139 , Issue.2 , pp. 121-127
    • Maxwell, P.1    van den Berg, H.W.2
  • 145
    • 0041352038 scopus 로고    scopus 로고
    • Hormonal control of IGF-binding protein (IGFBP)-5 and IGFBP-2 secretion during differentiation of the HC11 mouse mammary epithelial cell line
    • Phillips K., et al. Hormonal control of IGF-binding protein (IGFBP)-5 and IGFBP-2 secretion during differentiation of the HC11 mouse mammary epithelial cell line. J. Mol. Endocrinol. 2003, 31(1):197-208.
    • (2003) J. Mol. Endocrinol. , vol.31 , Issue.1 , pp. 197-208
    • Phillips, K.1
  • 146
    • 77951028448 scopus 로고    scopus 로고
    • Genetic screen identifies insulin-like growth factor binding protein 5 as a modulator of tamoxifen resistance in breast cancer
    • Ahn B.Y., et al. Genetic screen identifies insulin-like growth factor binding protein 5 as a modulator of tamoxifen resistance in breast cancer. Cancer Res. 2010, 70(8):3013-3019.
    • (2010) Cancer Res. , vol.70 , Issue.8 , pp. 3013-3019
    • Ahn, B.Y.1
  • 147
    • 0033573204 scopus 로고    scopus 로고
    • Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells
    • Perks C.M., et al. Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells. J. Cell. Biochem. 1999, 75(4):652-664.
    • (1999) J. Cell. Biochem. , vol.75 , Issue.4 , pp. 652-664
    • Perks, C.M.1
  • 148
    • 0033809981 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 (IGFBP-3) potentiates paclitaxel-induced apoptosis in human breast cancer cells
    • Fowler C.A., et al. Insulin-like growth factor binding protein-3 (IGFBP-3) potentiates paclitaxel-induced apoptosis in human breast cancer cells. Int. J. Cancer 2000, 88(3):448-453.
    • (2000) Int. J. Cancer , vol.88 , Issue.3 , pp. 448-453
    • Fowler, C.A.1
  • 149
    • 33745149031 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein 3 has opposing actions on malignant and nonmalignant breast epithelial cells that are each reversible and dependent upon cholesterol-stabilized integrin receptor complexes
    • Burrows C., et al. Insulin-like growth factor binding protein 3 has opposing actions on malignant and nonmalignant breast epithelial cells that are each reversible and dependent upon cholesterol-stabilized integrin receptor complexes. Endocrinology 2006, 147(7):3484-3500.
    • (2006) Endocrinology , vol.147 , Issue.7 , pp. 3484-3500
    • Burrows, C.1
  • 150
    • 0023304864 scopus 로고
    • Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines
    • Davidson N.E., et al. Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol. Endocrinol. 1987, 1(3):216-223.
    • (1987) Mol. Endocrinol. , vol.1 , Issue.3 , pp. 216-223
    • Davidson, N.E.1
  • 151
    • 0022631868 scopus 로고
    • Induction of epidermal growth factor-related polypeptides by 17 beta-estradiol in MCF-7 human breast cancer cells
    • Dickson R.B., et al. Induction of epidermal growth factor-related polypeptides by 17 beta-estradiol in MCF-7 human breast cancer cells. Endocrinology 1986, 118(1):138-142.
    • (1986) Endocrinology , vol.118 , Issue.1 , pp. 138-142
    • Dickson, R.B.1
  • 152
    • 0037338707 scopus 로고    scopus 로고
    • Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor
    • Levin E.R. Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor. Mol. Endocrinol. 2003, 17(3):309-317.
    • (2003) Mol. Endocrinol. , vol.17 , Issue.3 , pp. 309-317
    • Levin, E.R.1


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