Insulin-like growth factor binding protein (IGFBP)-3 protease activity secreted by MCF-7 breast cancer cells: Inhibition by IGFs does not require IGF-IGFBP interaction

Endocrinology

Volumn 138, Issue 4, 1997, Pages 1683-1690

  Salahifar, Houta ^a   Baxter, Robert C ^a   Martin, Janet L ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; BENZAMIDINE; EDETIC ACID; LEUPEPTIN; PROTEINASE; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN 3;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL FREE SYSTEM; CULTURE MEDIUM; ENZYME ACTIVITY; GEL CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

EID: 0030909663     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.4.5064     Document Type: Article

References (51)

1. Macaulay VM 1992 Insulin-like growth factors and cancer. Br J Cancer 65:311-320
2. LeRoith D, Baserga R, Helman L, Roberts, Jr, CT 1995 Insulin-like growth factors and cancer. Ann Intern Mod 122:54-59
3. Cullen KJ, Allison A, Martire I, Ellis M, Singer C 1992 Insulin-like growth factor expression in breast cancer epithelium and stroma. Breast Cancer Res Treat 22:21-29
4. Yee D, Cullen KJ, Paik S, Perdue JF, Hampton B, Schwartz A, Lippman ME, Rosen N 1988 Insulin-like growth factor II mRNA expression in human breast cancer. Cancer Res 48:6691-6696
5. Dickson RB, Johnson MD, Bano M, Shi E, Kurebayashi J, Ziff B, Martinez LI, Amundadottir LT, Lippman ME 1992 Growth factors in breast cancer: mitogenesis to transformation. J Steroid Biochem Mol Biol 43:69-78
6. Baxter RC, Martin JL 1989 Binding proteins for the insulin-like growth factors: structure, regulation and function. Prog Growth Factor Res 1:49-68
7. Rechler MM, Brown AL 1992 Insulin-like growth factor binding proteins: gene structure and expression. Growth Regul 2:55-68
8. Drop SLS, Schuller AGP, Lindenbergh-Kortleve DJ, Groffen C, Brinkman A, Zwarthoff EC 1992 Structural aspects of the IGFBP family. Growth Regul 2:69-79
9. Jones JI, Gockerman A, Busby WH, Camacho-Hubner C, Clemmons DR 1993 Extracellular matrix contains insulin-like growth factor binding protein-5-potentiation of the effects of IGF-I. J Cell Biol 121:679-687
10. Baxter RC 1993 Insulin-like growth factor-binding proteins: biochemical characterization. In: Muller EE, Cocchi D, Locatelli V (ed) Growth Hormone and Somatomedins during Lifespan. Springer-Verlag, Berlin, pp 100-108
11. Booth BA, Boes M, Andress DL, Dake BL, Kiefer MC, Maack C, Linhardt RJ, Bar K, Caldwell EE, Weiler J 1995 IGFBP-3 and IGFBP-5 association with endothelial cells: role of C-terminal heparin binding domain. Growth Regul 5:1-17
12. DeMellow JSM, Baxter RC 1988 Growth hormone-dependent insulin-like growth factor (IGF) binding protein both inhibits and potentiates IGF-I-stimulated DNA synthesis in human skin fibroblasts. Biochem Biophys Res Commun 156:199-204
13. Conover CA 1991 Glycosylation of insulin-like growth factor binding protein-3 (IGFBP-3) is not required for potentiation of IGF-1 action: evidence for processing of cell-bound IGFBP-3. Endocrinology 129:3259-3268
14. Kwaan HC 1992 The plasminogen/plasmin system in malignancy. Cancer Metastasis Rev 11:291-311
15. Conover CA, DeLeon DD 1994 Acid-activated insulin-like growth factor-binding protein-3 proteolysis in normal and transformed cells: role of cathepsin D. J Biol Chem 269:7076-7080
16. Cohen P, Graves HCB, Peehl DM, Kamarei M, Guidice LC, Rosenfeld RG 1992 Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab 75:1046-1053
17. Hossenlopp P, Segovia B, Lassarre C, Roghani M, Bredon M, Binoux M 1990 Evidence of enzymatic degradtion of insulin-like growth factor-binding proteins in the 150 K complex during pregnancy. J Clin Endocrinol Metab 71:797-805
18. Guidice LC, Farrell EM, Pham H, Lamson G, Rosenfeld RG 1990 Insulin-like growth factor binding proteins in maternal serum through gestation and in the puerpium: effects of a pregnancy-associated serum protease activity. J Clin Endocrinol Metab 71:806-816
19. Lalou C, Silve C, Rosato R, Segovia B, Binoux M 1994 Interactions between insulin-like growth factor-I (IGF-I) and the system of plasminogen activators and their inhibitors in the control of IGF-binding protein-3 production and proteolysis in human osteosarcoma cells. Endocrinology 135:2318-2326
20. Conover CA 1992 Potentiation of insulin-like growth factor (IGF) action by IGF-binding protein-3: studies of underlying mechanism. Endocrinology 130:3191-3199
21. Martin JL, Baxter RC 1986 Insulin-like growth factor binding protein from human plasma: purification and characterization. J Biol Chem 261:8754-8760
22. Baxter RC, Martin JL 1986 Radioimmunoassay of growth hormone-dependent insulin-like growth factor binding protein in human plasma. J Clin Invest 78:1504-1512
23. Martin JL, Coverley JA, Pattison ST, Baxter RC 1995 Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-6 production by MCF-7 breast cancer cells: stimulation by retinoic acid and cyclic AMP, and differential effects of estradiol. Endocrinology 136:1219-1226
24. Suikkari A-M, Baxter RC 1992 Insulin-like growth factor (IGF) binding protein-3 is functionally normal in pregnancy serum. J Clin Endocrinol Metab 74:177-183
25. Camacho-Hubner C, Busby, Jr, WH, McCusker RH, Wright G, Clemmons DR 1992 Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion. J Biol Chem 267:11949-11956
26. Fielder PJ, Rosenfeld RG, Graves HC, Grandbois K, Maack CA, Sawamura S, Ogawa Y, Sommer A, Cohen P1994 Biochemical analysis of prostate specific antigen-proteolyzed insulin-like growth factor binding protein-3. Growth Regul 4:164-172
27. Conover CA, Kiefer MC, Zapf J 1993 Posttranslational regulation of insulin-like growth factor binding protein-4 in normal and transformed human fibroblasts-insulin-like growth factor dependence and biological studies. J Clin Invest 91:1129-1137
28. Cohick WS, Gockerman A, Clemmons DR 1995 Regulation of insulin-like growth factor (IGF) binding protein-2 synthesis and degradation by platelet-derived growth factor and the IGFs is enhanced by serum deprivation in vascular smooth muscle cells. J Cell Physiol 164:187-196
29. Lord APD, Bastian SEP, Read LC, Walton PE, Ballard FJ 1994 Differences in the association of insulin-like growth factor-I (IGF-I) and IGF-I variants with rat, sheep, pig, human and chicken plasma-binding proteins. J Endocrinol 140:475-482
30. Morris DH, Schalch DS 1982 Structure of the somatomedin-binding protein: alkaline pH-induced dissociation of an acid-stable, 60,000 molecular weight complex into smaller components. Endocrinology 111:801-805
31. Davies SC, Wass JAH, Ross RJM, Cotterill AM, Buchanan CR, Coulson VJ, Holly JMP 1991 The induction of a specific protease for insulin-like growth factor binding protein-3 in the circulation during severe illness. J Endocrinol 130:469-473
32. Muller HL, Oh Y, Gargosky SE, Wilson KF, Lehrnbecher T, Rosenfeld RG 1994 Insulin-like growth factor binding protein-3 concentrations and insulin-like growth factor binding protein-3 protease activity in sera of patients with malignant solid tumors or leukemia. Pediatr Res 35:720-724
33. Fowlkes JL, Enghild JJ, Suzuki K, Nagase H 1994 Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures. J Biol Chem 269:25742-25746
34. Lalou C, Lassarre C, Bionoux M 1996 A proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 that fails to bind IGFs inhibits the mitogenic effects of IGF-I and insulin. Endocrinology 137:3206-3212
35. Firth SM, Baxter RC 1995 The role of glycosylation in the action of IGFBP-3. Prog Growth Factor Res 6:223-229
36. Baxter RC, Firth SM 1995 Modulation of human IGF binding protein-3 activity by structural modification. Prog Growth Factor Res 6:215-222
37. Cohen P, Peehl DM, Graves HCB, Rosenfeld RG 1994 Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease. J Endocrinol 142:407-415
38. Ho PJ, Baxter RC, Insulin-like growth factor-binding protein-2 in milk. Program of the 76th Annual Meeting of The Endocrine Society, Anaheim CA, 1992, p 436 (Abstract)
39. Martin JL, Ballesteros M, Baxter RC 1992 Insulin-like growth factor-I (IGF-I) and transforming growth factor-β1 release IGF binding protein-3 from human fibroblasts by different mechanisms. Endocrinology 131:1703-1710
40. Chernausek SD, Smith CE, Duffin KL, Busby WH, Wright G, Clemmons DR 1995 Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4): localization of cleavage site to non-homologous region of native IGFBP-4. J Biol Chem 270:11377-11382
41. Angelloznicoud P, Binoux M 1995 Autocrine regulation of cell proliferation by the insulin-like growth factor (IGF) and IGF-binding protein-3 protease system in a human prostate carcinoma cell line (PC-3). Endocrinology 136:5485-5492
42. Durham SK, Riggs BL, Harris SA, Conover CA 1995 Alterations in insulin-like growth factor (IGF)-dependent IGF-binding protein-4 proteolysis in transformed osteoblastic cells. Endocrinology 136:1374-1380
43. Grimes RW, Hammond JM 1994 Proteolytic degradation of insulin-like growth factor (IGF)-binding protein-3 by porcine ovarian granulosa cells in culture: regulation by IGF-I. Endocrinology 134:337-343
44. Ryan RE, Sloane BF, Sameni M, Wood PL 1995 Microglial cathepsin B: an immunological examination of cellular and secreted species. J Neurochem 65:1035-1045
45. Gillies RJ, Martinez-Zaguilan R, Martinez GM, Serrano R, Perona R 1990 Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proc Natl Acad Sci USA 87:7414-7418
46. Vaupel P, Kallinowski F, Okunieff P 1989 Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 49:6449-6465
47. Pratt SE, Pollak MN 1994 Insulin-like growth factor binding protein 3 (IGF-BP3) inhibits estrogen-stimulated breast cancer cell proliferation. Biochem Biophys Res Commun 198:292-297
48. Chen JC, Shao ZM, Sheikh MS, Hussain A, Leroith D, Roberts CT, Fontana JA 1994 Insulin-like growth factor-binding protein enhancement of insulin-like growth factor-I (IGF-I)-mediated DNA synthesis and IGF-I binding in a human breast carcinoma cell line. J Cell Physiol 158:69-78
49. Martin JL, Baxter RC 1992 Inhibition of human fibroblast insulin-like growth factor binding protein (IGFBP) production by IGFBP-3. Endocrinology 131:1568-1570
50. Fowlkes JL, Serra DM, Rosenberg CK, Thrailkill KM 1995 Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) functions as an IGF-reversible inhibitor of IGFBP-4 proteolysis. J Biol Chem 270:27481-27488
51. Donnelly MJ, Holly JMP 1996 The role of IGFBP-3 in the regulation of IGFBP-4 proteolysis. J Endocrinol 149:R1-R7