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Volumn 32, Issue 6, 2013, Pages 678-688

Insulin-like growth factor-I regulates GPER expression and function in cancer cells

Author keywords

cancer cells; ERa; GPER; IGF I; signal transduction

Indexed keywords

CYCLIN D1; ESTROGEN RECEPTOR ALPHA; G PROTEIN COUPLED RECEPTOR 30; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; PROTEIN KINASE C DELTA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR AP 1;

EID: 84873743039     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.97     Document Type: Article
Times cited : (88)

References (54)
  • 1
    • 4444373076 scopus 로고    scopus 로고
    • Prevention of cancers of the breast, endometrium and ovary
    • Pike MC, Pearce CL, Wu AH. Prevention of cancers of the breast, endometrium and ovary. Oncogene 2004; 23: 6379-6391.
    • (2004) Oncogene , vol.23 , pp. 6379-6391
    • Pike, M.C.1    Pearce, C.L.2    Wu, A.H.3
  • 2
    • 62749085753 scopus 로고    scopus 로고
    • Breast cancer, estrogen receptor and ligands
    • Bai Z, Gust R. Breast cancer, estrogen receptor and ligands. Arch Pharm (Weinheim) 2009; 342: 133-149.
    • (2009) Arch Pharm (Weinheim) , vol.342 , pp. 133-149
    • Bai, Z.1    Gust, R.2
  • 3
    • 0023808861 scopus 로고
    • The estrogen receptor binds to its responsive element as a ligand-induced homodimer
    • Kumar V, Chambon P. The estrogen receptor binds to its responsive element as a ligand-induced homodimer. Cell 1988; 55: 145-156.
    • (1988) Cell , vol.55 , pp. 145-156
    • Kumar, V.1    Chambon, P.2
  • 4
    • 0024559926 scopus 로고
    • Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements
    • Tsai SY, Tsai MJ, O' Malley BW. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell 1989; 57: 443-448.
    • (1989) Cell , vol.57 , pp. 443-448
    • Tsai, S.Y.1    Tsai, M.J.2    O'Malley, B.W.3
  • 5
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005; 146: 624-632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 6
    • 53249101612 scopus 로고    scopus 로고
    • The novel estrogen receptor GPR30 mediates the proliferative effects induced by17ßestradiol on mouse spermatogonial GC-1 cell line
    • Sirianni R, Chimento A, Ruggiero G, De Luca A, Lappano R, Andò S et al. The novel estrogen receptor GPR30 mediates the proliferative effects induced by17ßestradiol on mouse spermatogonial GC-1 cell line. Endocrinology 2008; 149: 5043-5051.
    • (2008) Endocrinology , vol.149 , pp. 5043-5051
    • Sirianni, R.1    Chimento, A.2    Ruggiero, G.3    De Luca, A.4    Lappano, R.5    Andò, S.6
  • 7
    • 67349105361 scopus 로고    scopus 로고
    • Mechanisms of estrogen signaling and gene expression via GPR30
    • Prossnitz ER, Maggiolini M. Mechanisms of estrogen signaling and gene expression via GPR30. Mol Cell Endocrinol 2009; 308: 32-38.
    • (2009) Mol Cell Endocrinol , vol.308 , pp. 32-38
    • Prossnitz, E.R.1    Maggiolini, M.2
  • 8
    • 75149186664 scopus 로고    scopus 로고
    • The unfolding stories of GPR30, a new membrane-bound estrogen receptor
    • Maggiolini M, Picard D. The unfolding stories of GPR30, a new membrane-bound estrogen receptor. J Endocrinol 2010; 204: 105-114.
    • (2010) J Endocrinol , vol.204 , pp. 105-114
    • Maggiolini, M.1    Picard, D.2
  • 9
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1and Erk-2 requires the G protein-coupled receptor homolog GPR30, and occurs via transactivation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton Jr AR. Estrogen-induced activation of Erk-1and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via transactivation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 2000; 14: 1649-1660.
    • (2000) Mol Endocrinol , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton Jr., A.R.4
  • 10
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein coupled receptor GPR30:stimulation of adenylyl cyclase and c-AMP mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo EJ, Quinn JA, Frackelton Jr AR, Bland KI. Estrogen action via the G protein coupled receptor, GPR30:stimulation of adenylyl cyclase and c-AMP mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol Endocrinol 2002; 16: 70-84.
    • (2002) Mol Endocrinol , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton Jr., A.R.3    Bland, K.I.4
  • 11
    • 33847755409 scopus 로고    scopus 로고
    • G proteincoupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17b-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A et al. G proteincoupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17b-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 2007; 67: 1859-1866.
    • (2007) Cancer Res , vol.67 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6
  • 12
    • 62049084027 scopus 로고    scopus 로고
    • Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
    • Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D. Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. EMBO J 2009; 28: 523-532.
    • (2009) EMBO J , vol.28 , pp. 523-532
    • Pandey, D.P.1    Lappano, R.2    Albanito, L.3    Madeo, A.4    Maggiolini, M.5    Picard, D.6
  • 13
    • 3042547161 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17 beta-estradiol and phytoestrogens in breast cancer cells
    • Maggiolini M, Vivacqua A, Fasanella G, Recchia AG, Sisci D, Pezzi V et al. The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17 beta-estradiol and phytoestrogens in breast cancer cells. J Biol Chem 2004; 279: 27008-27016.
    • (2004) J Biol Chem , vol.279 , pp. 27008-27016
    • Maggiolini, M.1    Vivacqua, A.2    Fasanella, G.3    Recchia, A.G.4    Sisci, D.5    Pezzi, V.6
  • 14
    • 47949111993 scopus 로고    scopus 로고
    • Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells
    • Albanito L, Sisci D, Aquila S, Brunelli E, Vivacqua A, Madeo A et al. Epidermal growth factor induces G protein-coupled receptor 30 expression in estrogen receptor-negative breast cancer cells. Endocrinology 2008; 149: 3799-3808.
    • (2008) Endocrinology , vol.149 , pp. 3799-3808
    • Albanito, L.1    Sisci, D.2    Aquila, S.3    Brunelli, E.4    Vivacqua, A.5    Madeo, A.6
  • 15
    • 70350449695 scopus 로고    scopus 로고
    • G proteincoupled receptor 30 expression is up-regulated by EGF and TGF a in estrogen receptor alpha-positive cancer cells
    • Vivacqua A, Lappano R, De Marco P, Sisci D, Aquila S, De Amicis F et al. G proteincoupled receptor 30 expression is up-regulated by EGF and TGF a in estrogen receptor alpha-positive cancer cells. Mol Endocrinol 2009; 23: 1815-1826.
    • (2009) Mol Endocrinol , vol.23 , pp. 1815-1826
    • Vivacqua, A.1    Lappano, R.2    De Marco, P.3    Sisci, D.4    Aquila, S.5    De Amicis, F.6
  • 16
    • 33751272253 scopus 로고    scopus 로고
    • Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinic pathologic determinants of tumor progression
    • Filardo EJ, Graeber CT, Quinn JA, Resnick MB, Giri D, De Lellis RA et al. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinic pathologic determinants of tumor progression. Clin Cancer Res 2006; 12: 6359-6366.
    • (2006) Clin Cancer Res , vol.12 , pp. 6359-6366
    • Filardo, E.J.1    Graeber, C.T.2    Quinn, J.A.3    Resnick, M.B.4    Giri, D.5    De Lellis, R.A.6
  • 18
    • 0029973924 scopus 로고    scopus 로고
    • Growth, differentiation, and survival multiple physiological functions for insulin-like growth factors
    • Stewart CE, Rotwein P. Growth, differentiation, and survival multiple physiological functions for insulin-like growth factors. Physiol Rev 1996; 76: 1005-1026.
    • (1996) Physiol Rev , vol.76 , pp. 1005-1026
    • Stewart, C.E.1    Rotwein, P.2
  • 19
    • 0038398622 scopus 로고    scopus 로고
    • The insulin-like growth factor system and cancer
    • LeRoith D, Roberts Jr CT. The insulin-like growth factor system and cancer. Cancer Lett 2003; 195: 127-137.
    • (2003) Cancer Lett , vol.195 , pp. 127-137
    • Leroith, D.1    Roberts Jr., C.T.2
  • 20
    • 57149142057 scopus 로고    scopus 로고
    • IGF and insulin receptor signaling in breast cancer
    • Belfiore A, Frasca F. IGF and insulin receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia 2008; 13: 381-406.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 381-406
    • Belfiore, A.1    Frasca, F.2
  • 21
    • 77956230328 scopus 로고    scopus 로고
    • Defining the pathway to insulin-like growth factor system targeting in cancer
    • Rosenzweig SA, Atreya HS. Defining the pathway to insulin-like growth factor system targeting in cancer. Biochem Pharmacol 2010; 80: 1115-1124.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1115-1124
    • Rosenzweig, S.A.1    Atreya, H.S.2
  • 22
    • 34047174592 scopus 로고    scopus 로고
    • The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer
    • Belfiore A. The role of insulin receptor isoforms and hybrid insulin/IGF-I receptors in human cancer. Curr Pharm Des 2007; 13: 671-686.
    • (2007) Curr Pharm des , vol.13 , pp. 671-686
    • Belfiore, A.1
  • 23
    • 57149146434 scopus 로고    scopus 로고
    • The role of endocrine insulin-like growth factor-I and insulin in breast cancer
    • Lann D, LeRoith D. The role of endocrine insulin-like growth factor-I and insulin in breast cancer. J Mammary Gland Biol Neoplasia 2008; 13: 371-379.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 371-379
    • Lann, D.1    Leroith, D.2
  • 24
    • 34249739150 scopus 로고    scopus 로고
    • Estrogen receptor and the activating protein-1 complex cooperate during insulin-like growth factor-i-induced transcriptional activation of the pS2/TFF1gene
    • Baron S, Escande A, Alberola G, Bystricky K, Balaguer P, Richard-Foy H. Estrogen receptor and the activating protein-1 complex cooperate during insulin-like growth factor-i-induced transcriptional activation of the pS2/TFF1gene. J Biol Chem 2007; 282: 11732-11741.
    • (2007) J Biol Chem , vol.282 , pp. 11732-11741
    • Baron, S.1    Escande, A.2    Alberola, G.3    Bystricky, K.4    Balaguer, P.5    Richard-Foy, H.6
  • 25
    • 33947493624 scopus 로고    scopus 로고
    • Insulin-like growth factor1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells
    • Cascio S, Bartella V, Garofalo C, Russo A, Giordano A, Surmacz E. Insulin-like growth factor1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J Biol Chem 2007; 282: 3498-3506.
    • (2007) J Biol Chem , vol.282 , pp. 3498-3506
    • Cascio, S.1    Bartella, V.2    Garofalo, C.3    Russo, A.4    Giordano, A.5    Surmacz, E.6
  • 26
    • 10944260245 scopus 로고    scopus 로고
    • Estrogen and insulin/IGF-1cooperatively stimulate cell cycle progression in MCF7 breast cancer cells through differential regulation of c-Myc and cyclin D1
    • Mawson A, Lai A, Carroll JS, Sergio CM, Mitchell CJ, Sarcevic B. Estrogen and insulin/IGF-1cooperatively stimulate cell cycle progression in MCF7 breast cancer cells through differential regulation of c-Myc and cyclin D1. Mol Cell Endocrinol 2005; 229: 161-173.
    • (2005) Mol Cell Endocrinol , vol.229 , pp. 161-173
    • Mawson, A.1    Lai, A.2    Carroll, J.S.3    Sergio, C.M.4    Mitchell, C.J.5    Sarcevic, B.6
  • 27
    • 57149137029 scopus 로고    scopus 로고
    • Cross talk between IGF1R and estrogen receptor signaling in breast cancer
    • Fagan DH, Yee D. Cross talk between IGF1R and estrogen receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia 2008; 13: 423-429.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 423-429
    • Fagan, D.H.1    Yee, D.2
  • 28
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato S, Endoh H, Masuhiro Y, Kitamoto T, Uchiyama S, Sasaki H et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995; 270: 1491-1494.
    • (1995) Science , vol.270 , pp. 1491-1494
    • Kato, S.1    Endoh, H.2    Masuhiro, Y.3    Kitamoto, T.4    Uchiyama, S.5    Sasaki, H.6
  • 29
    • 78650845707 scopus 로고    scopus 로고
    • G protein-coupled receptors: Novel targets for drug discovery in cancer
    • Lappano R, Maggiolini M. G protein-coupled receptors: novel targets for drug discovery in cancer. Nat Rev Drug Discov 2011; 10: 47-60.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 47-60
    • Lappano, R.1    Maggiolini, M.2
  • 30
    • 77957660483 scopus 로고    scopus 로고
    • Crosstalk between insulin receptor and G protein coupled receptor signaling systems leads to Ca2+ oscillations in pancreatic cancer PANC-1 cells
    • Young SH, Rozengurt E. Crosstalk between insulin receptor and G protein coupled receptor signaling systems leads to Ca2+ oscillations in pancreatic cancer PANC-1 cells. Biochem Biophys Res Commun 2010; 401: 154-158.
    • (2010) Biochem Biophys Res Commun , vol.401 , pp. 154-158
    • Young, S.H.1    Rozengurt, E.2
  • 31
    • 69249162223 scopus 로고    scopus 로고
    • Metformin disrupts cross talk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth
    • Kisfalvi K, Eibl G, Sinnett-Smith J, Rozengurt E. Metformin disrupts cross talk between G protein-coupled receptor and insulin receptor signaling systems and inhibits pancreatic cancer growth. Cancer Res 2009; 69: 6539-6545.
    • (2009) Cancer Res , vol.69 , pp. 6539-6545
    • Kisfalvi, K.1    Eibl, G.2    Sinnett-Smith, J.3    Rozengurt, E.4
  • 32
    • 33748923143 scopus 로고    scopus 로고
    • 17b Estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein coupled-receptor GPR30
    • Vivacqua A, Bonofiglio D, Albanito L, Madeo A, Rago V, Carpino A et al. 17b Estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein coupled-receptor GPR30. Mol Pharmacol 2006; 70: 1414-1423.
    • (2006) Mol Pharmacol , vol.70 , pp. 1414-1423
    • Vivacqua, A.1    Bonofiglio, D.2    Albanito, L.3    Madeo, A.4    Rago, V.5    Carpino, A.6
  • 33
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17b-estradiol and hydroxytamoxifen in endometrial cancer cells
    • Vivacqua A, Bonofiglio D, Recchia AG, Musti AM, Picard D, Ando S et al. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17b-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 2006; 20: 631-646.
    • (2006) Mol Endocrinol , vol.20 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3    Musti, A.M.4    Picard, D.5    Ando, S.6
  • 34
    • 12344252237 scopus 로고    scopus 로고
    • AP-1subunits: Quarrel and harmony among siblings
    • Hess J, Angel P, Schorpp-Kistner M. AP-1subunits: quarrel and harmony among siblings. J Cell Sci 2004; 117: 5965-5973.
    • (2004) J Cell Sci , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 35
    • 77955024164 scopus 로고    scopus 로고
    • Nuclear alternate estrogen receptor GPR30 mediates 17bestradiol-induced gene expression and migration in breast cancer-associated fibroblasts
    • Madeo A, Maggiolini M. Nuclear alternate estrogen receptor GPR30 mediates 17bestradiol-induced gene expression and migration in breast cancer-associated fibroblasts. Cancer Res 2010; 70: 6036-6046.
    • (2010) Cancer Res , vol.70 , pp. 6036-6046
    • Madeo, A.1    Maggiolini, M.2
  • 36
    • 9244227134 scopus 로고    scopus 로고
    • Stromal fibroblasts in cancer initiation and progression
    • Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004; 432: 332-337.
    • (2004) Nature , vol.432 , pp. 332-337
    • Bhowmick, N.A.1    Neilson, E.G.2    Moses, H.L.3
  • 37
    • 34547095246 scopus 로고    scopus 로고
    • Estrogen signaling via a linear pathway involving insulin-like growth factor i receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogenactivated protein kinase in MCF-7 breast cancer cells
    • Song RX, Zhang Z, Chen Y, Bao Y, Santen RJ. Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogenactivated protein kinase in MCF-7 breast cancer cells. Endocrinology 2007; 148: 4091-4101.
    • (2007) Endocrinology , vol.148 , pp. 4091-4101
    • Song, R.X.1    Zhang, Z.2    Chen, Y.3    Bao, Y.4    Santen, R.J.5
  • 38
    • 40849123722 scopus 로고    scopus 로고
    • Role of insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line
    • Bradley LM, Gierthy JF, Pentecost BT. Role of insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line. J Steroid Biochem Mol Biol 2008; 109: 185-196.
    • (2008) J Steroid Biochem Mol Biol , vol.109 , pp. 185-196
    • Bradley, L.M.1    Gierthy, J.F.2    Pentecost, B.T.3
  • 39
    • 0025635904 scopus 로고
    • Role of insulin-like growth factors and the type i insulin-like growth factor receptor in the estrogenstimulated proliferation of human breast cancer cells
    • Stewart AJ, Johnson MD, May FE, Westley BR. Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogenstimulated proliferation of human breast cancer cells. J Biol Chem 1990; 265: 21172-21178.
    • (1990) J Biol Chem , vol.265 , pp. 21172-21178
    • Stewart, A.J.1    Johnson, M.D.2    May, F.E.3    Westley, B.R.4
  • 40
    • 78650968836 scopus 로고    scopus 로고
    • Interactions between IGF-I, estrogen receptor-A (ERa), and ERb in regulating growth/apoptosis of MCF-7 human breast cancer cells
    • Mendoza RA, Enriquez MI, Mejia SM, Moody EE, Thordarson G. Interactions between IGF-I, estrogen receptor-a (ERa), and ERb in regulating growth/apoptosis of MCF-7 human breast cancer cells. J Endocrinol 2011; 208: 1-9.
    • (2011) J Endocrinol , vol.208 , pp. 1-9
    • Mendoza, R.A.1    Enriquez, M.I.2    Mejia, S.M.3    Moody, E.E.4    Thordarson, G.5
  • 41
    • 0027502045 scopus 로고
    • Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity
    • Soos MA, Field CE, Siddle K. Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem J 1993; 290: 419-426.
    • (1993) Biochem J , vol.290 , pp. 419-426
    • Soos, M.A.1    Field, C.E.2    Siddle, K.3
  • 42
    • 0032800850 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: Evidence for a second mechanism of IGF-I signaling
    • Pandini G, Vigneri R, Costantino A, Frasca F, Ippolito A, Fujita-Yamaguchi Y et al. Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. Clin Cancer Res 1999; 5: 1935-1944.
    • (1999) Clin Cancer Res , vol.5 , pp. 1935-1944
    • Pandini, G.1    Vigneri, R.2    Costantino, A.3    Frasca, F.4    Ippolito, A.5    Fujita-Yamaguchi, Y.6
  • 43
    • 77953742040 scopus 로고    scopus 로고
    • The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells
    • Zhang G, Li X, Zhang L, Zhao L, Jiang J, Wang J et al. The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells. Cancer Genet Cytogenet 2010; 200: 140-148.
    • (2010) Cancer Genet Cytogenet , vol.200 , pp. 140-148
    • Zhang, G.1    Li, X.2    Zhang, L.3    Zhao, L.4    Jiang, J.5    Wang, J.6
  • 44
    • 33845906843 scopus 로고    scopus 로고
    • All in the CCN family: Essential matricellular signaling modulators emerge from the bunker
    • Leask A, Abraham DJ. All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci 2006; 23: 4803-4810.
    • (2006) J Cell Sci , vol.23 , pp. 4803-4810
    • Leask, A.1    Abraham, D.J.2
  • 45
    • 53149092430 scopus 로고    scopus 로고
    • The CCN family of proteins: Structure-function relationships
    • Holbourn KP, Acharya KR, Perbal B. The CCN family of proteins: structure-function relationships. Trends Biochem Sci 2008; 33: 461-473.
    • (2008) Trends Biochem Sci , vol.33 , pp. 461-473
    • Holbourn, K.P.1    Acharya, K.R.2    Perbal, B.3
  • 46
    • 79952234041 scopus 로고    scopus 로고
    • Extranuclear signaling by estrogen: Role in breast cancer progression and metastasis
    • Cortez V, Mann M, Brann DW, Vadlamudi RK. Extranuclear signaling by estrogen: role in breast cancer progression and metastasis. Minerva Ginecol 2010; 62: 573-583.
    • (2010) Minerva Ginecol , vol.62 , pp. 573-583
    • Cortez, V.1    Mann, M.2    Brann, D.W.3    Vadlamudi, R.K.4
  • 47
    • 0030752456 scopus 로고    scopus 로고
    • Estrogen receptors alpha and beta form heterodimers on DNA
    • Cowley SM, Hoare S, Mosselman S, Parker MG. Estrogen receptors alpha and beta form heterodimers on DNA. J Biol Chem 1997; 272: 19858-19862.
    • (1997) J Biol Chem , vol.272 , pp. 19858-19862
    • Cowley, S.M.1    Hoare, S.2    Mosselman, S.3    Parker, M.G.4
  • 48
    • 0030683639 scopus 로고    scopus 로고
    • Signal characteristics of G protein-transactivated EGF receptor
    • Daub H, Wallasch C, Lankenau A, Herrlich A, Ullrich A. Signal characteristics of G protein-transactivated EGF receptor. EMBO J 1997; 16: 7032-7044.
    • (1997) EMBO J , vol.16 , pp. 7032-7044
    • Daub, H.1    Wallasch, C.2    Lankenau, A.3    Herrlich, A.4    Ullrich, A.5
  • 49
    • 0035844282 scopus 로고    scopus 로고
    • Insulin and Insulin-like growth factor i receptors utilize different G protein signaling components
    • Dalle S, Ricketts W, Imamura T, Vollenweider P, Olefsky JM. Insulin and Insulin-like growth factor I receptors utilize different G protein signaling components. J Biol Chem 2001; 276: 15688-15695.
    • (2001) J Biol Chem , vol.276 , pp. 15688-15695
    • Dalle, S.1    Ricketts, W.2    Imamura, T.3    Vollenweider, P.4    Olefsky, J.M.5
  • 50
    • 77951708711 scopus 로고    scopus 로고
    • Cross talk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: A novel target for the antidiabetic drug metformin in pancreatic cancer
    • Rozengurt E, Sinnett-Smith J, Kisfalvi K. Cross talk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clin Cancer Res 2010; 16: 2505-2511.
    • (2010) Clin Cancer Res , vol.16 , pp. 2505-2511
    • Rozengurt, E.1    Sinnett-Smith, J.2    Kisfalvi, K.3
  • 51
    • 28844458917 scopus 로고    scopus 로고
    • Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells
    • Akekawatchai C, Holland JD, Kochetkova M, Wallace JC, McColl SR. Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells. J Biol Chem 2005; 280: 39701-39708.
    • (2005) J Biol Chem , vol.280 , pp. 39701-39708
    • Akekawatchai, C.1    Holland, J.D.2    Kochetkova, M.3    Wallace, J.C.4    McColl, S.R.5
  • 52
    • 79953227087 scopus 로고    scopus 로고
    • The G protein-coupled receptor 30 is up-regulated by hypoxia inducible factor-1a (HIF-1a) in breast cancer cells and cardiomyocytes
    • Recchia AG, De Francesco EM, Vivacqua A, Sisci D, Panno ML, Andò S et al. The G protein-coupled receptor 30 is up-regulated by hypoxia inducible factor-1a (HIF-1a) in breast cancer cells and cardiomyocytes. J Biol Chem 2011; 286: 10773-10782.
    • (2011) J Biol Chem , vol.286 , pp. 10773-10782
    • Recchia, A.G.1    De Francesco, E.M.2    Vivacqua, A.3    Sisci, D.4    Panno, M.L.5    Andò, S.6
  • 53
    • 33746010588 scopus 로고    scopus 로고
    • Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappa B activation
    • Chaqour B, Yang R, Sha Q. Mechanical stretch modulates the promoter activity of the profibrotic factor CCN2 through increased actin polymerization and NF-kappa B activation. J Biol Chem 2006; 281: 20608-20622.
    • (2006) J Biol Chem , vol.281 , pp. 20608-20622
    • Chaqour, B.1    Yang, R.2    Sha, Q.3


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