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Volumn 18, Issue SUPPL. 6, 2007, Pages

The estrogen receptor α:insulin receptor substrate 1 complex in breast cancer: Structure-function relationships

Author keywords

Breast cancer; Estrogen receptor alpha (ERa); Insulin receptor substrate 1 (IRS 1)

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; INSULIN RECEPTOR SUBSTRATE 1; SOMATOMEDIN C; IFNGR2 PROTEIN, HUMAN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; INTERFERON RECEPTOR; PEPTIDE FRAGMENT; PHOSPHOPROTEIN; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

EID: 35748930595     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdm232     Document Type: Conference Paper
Times cited : (19)

References (33)
  • 1
    • 34047099280 scopus 로고    scopus 로고
    • Crosstalk between IGF signaling and steroid hormone receptors in breast cancer
    • Sisci D, Surmacz E. Crosstalk between IGF signaling and steroid hormone receptors in breast cancer. Curr Pharm Des 2007; 13: 705-717.
    • (2007) Curr Pharm Des , vol.13 , pp. 705-717
    • Sisci, D.1    Surmacz, E.2
  • 2
    • 0033838566 scopus 로고    scopus 로고
    • Function of the IGF-I receptor in breast cancer
    • Surmacz E. Function of the IGF-I receptor in breast cancer. J Mammary Gland Biol Neoplasia 2000; 5: 95-105.
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , pp. 95-105
    • Surmacz, E.1
  • 3
    • 0842291441 scopus 로고    scopus 로고
    • Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: Who will have the last word?
    • Lange CA. Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: Who will have the last word? Mol Endocrinol 2004; 18: 269-278.
    • (2004) Mol Endocrinol , vol.18 , pp. 269-278
    • Lange, C.A.1
  • 4
    • 0031840580 scopus 로고    scopus 로고
    • Ligand-independent activation of steroid hormone receptors
    • Weigel NL, Zhang Y. Ligand-independent activation of steroid hormone receptors. J Mol Med 1998; 76: 469-479.
    • (1998) J Mol Med , vol.76 , pp. 469-479
    • Weigel, N.L.1    Zhang, Y.2
  • 5
    • 0037211754 scopus 로고    scopus 로고
    • Estrogen receptor phosphorylation
    • Lannigan DA. Estrogen receptor phosphorylation. Steroids 2003; 68: 1-9.
    • (2003) Steroids , vol.68 , pp. 1-9
    • Lannigan, D.A.1
  • 6
    • 0027490328 scopus 로고
    • Modulators of cellular protein phosphorylation alter the trans-activation function of human progesterone receptor and the biological activity of progesterone antagonists
    • Edwards DP, Weigel NL, Nordeen SK, Beck CA. Modulators of cellular protein phosphorylation alter the trans-activation function of human progesterone receptor and the biological activity of progesterone antagonists. Breast Cancer Res Treat 1993; 27: 41-56.
    • (1993) Breast Cancer Res Treat , vol.27 , pp. 41-56
    • Edwards, D.P.1    Weigel, N.L.2    Nordeen, S.K.3    Beck, C.A.4
  • 7
    • 8344223854 scopus 로고    scopus 로고
    • Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: Implications for cell proliferation
    • Shupnik MA. Crosstalk between steroid receptors and the c-Src-receptor tyrosine kinase pathways: Implications for cell proliferation. Oncogene 2004; 23: 7979-7989.
    • (2004) Oncogene , vol.23 , pp. 7979-7989
    • Shupnik, M.A.1
  • 8
    • 0028286272 scopus 로고
    • Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer
    • Umayahara Y, Kawamori R, Watada H et al. Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J Biol Chem 1994; 269: 16433-16442.
    • (1994) J Biol Chem , vol.269 , pp. 16433-16442
    • Umayahara, Y.1    Kawamori, R.2    Watada, H.3
  • 9
    • 0025635904 scopus 로고
    • Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells
    • Stewart AJ, Johnson MD, May FE, Westley BR. Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. J Biol Chem 1990; 265: 21172-21178.
    • (1990) J Biol Chem , vol.265 , pp. 21172-21178
    • Stewart, A.J.1    Johnson, M.D.2    May, F.E.3    Westley, B.R.4
  • 10
    • 0033278993 scopus 로고    scopus 로고
    • Transcriptional activation of insulin-like growth factor-binding protein-4 by 17beta-estradiol in MCF-7 cells: Role of estrogen receptor-Sp1 complexes
    • Qin C, Singh P, Safe S. Transcriptional activation of insulin-like growth factor-binding protein-4 by 17beta-estradiol in MCF-7 cells: Role of estrogen receptor-Sp1 complexes. Endocrinology 1999; 140: 2501-2508.
    • (1999) Endocrinology , vol.140 , pp. 2501-2508
    • Qin, C.1    Singh, P.2    Safe, S.3
  • 11
    • 0032912182 scopus 로고    scopus 로고
    • Insulin receptor substrate 1 is a target for the pure antiestrogen ICI 182,780 in breast cancer cells
    • Salerno M, Sisci D, Mauro L et al. Insulin receptor substrate 1 is a target for the pure antiestrogen ICI 182,780 in breast cancer cells. Int J Cancer 1999; 81: 299-304.
    • (1999) Int J Cancer , vol.81 , pp. 299-304
    • Salerno, M.1    Sisci, D.2    Mauro, L.3
  • 12
    • 0034724886 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line
    • Molloy CA, May FE, Westley BR. Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line. J Biol Chem 2000; 275: 12565-12571.
    • (2000) J Biol Chem , vol.275 , pp. 12565-12571
    • Molloy, C.A.1    May, F.E.2    Westley, B.R.3
  • 13
    • 0033305004 scopus 로고    scopus 로고
    • Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
    • Lee AV, Jackson JG, Gooch JL et al. Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 1999; 13: 787-796.
    • (1999) Mol Endocrinol , vol.13 , pp. 787-796
    • Lee, A.V.1    Jackson, J.G.2    Gooch, J.L.3
  • 14
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signalling system and the IRS proteins
    • White MF. The insulin signalling system and the IRS proteins. Diabetologia 1997; 40 (Suppl 2): S2-S17.
    • (1997) Diabetologia , vol.40 , Issue.SUPPL. 2
    • White, M.F.1
  • 15
    • 0037053310 scopus 로고    scopus 로고
    • Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen
    • Lassak A, Del Valle L, Peruzzi F et al. Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen. J Biol Chem 2002; 277: 17231-17238.
    • (2002) J Biol Chem , vol.277 , pp. 17231-17238
    • Lassak, A.1    Del Valle, L.2    Peruzzi, F.3
  • 16
    • 0028364282 scopus 로고
    • Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3
    • Ma ZQ, Santagati S, Patrone C et al. Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3. Mol Endocrinol 1994; 8: 910-918.
    • (1994) Mol Endocrinol , vol.8 , pp. 910-918
    • Ma, Z.Q.1    Santagati, S.2    Patrone, C.3
  • 17
    • 34250827856 scopus 로고    scopus 로고
    • Expression of nuclear insulin receptor substrate 1 (IRS-1) in breast cancer
    • Epub ahead of print
    • Sisci D, Morelli C, Garofalo C et al. Expression of nuclear insulin receptor substrate 1 (IRS-1) in breast cancer. J Clin Pathol 2006; [Epub ahead of print].
    • (2006) J Clin Pathol
    • Sisci, D.1    Morelli, C.2    Garofalo, C.3
  • 18
    • 6344279925 scopus 로고    scopus 로고
    • Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters
    • Morelli C, Garofalo C, Sisci D et al. Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters. Oncogene 2004; 23: 7517-7526.
    • (2004) Oncogene , vol.23 , pp. 7517-7526
    • Morelli, C.1    Garofalo, C.2    Sisci, D.3
  • 20
    • 0023663885 scopus 로고
    • Functional domains of the human estrogen receptor
    • Kumar V, Green S, Stack G et al. Functional domains of the human estrogen receptor. Cell 1987; 51: 941-951.
    • (1987) Cell , vol.51 , pp. 941-951
    • Kumar, V.1    Green, S.2    Stack, G.3
  • 21
    • 0034464660 scopus 로고    scopus 로고
    • Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms
    • Platet N, Cunat S, Chalbos D et al. Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms. Mol Endocrinol 2000; 14: 999-1009.
    • (2000) Mol Endocrinol , vol.14 , pp. 999-1009
    • Platet, N.1    Cunat, S.2    Chalbos, D.3
  • 22
    • 10644220369 scopus 로고    scopus 로고
    • Fibronectin and type IV collagen activate ERalpha AF-1 by c-Src pathway: Effect on breast cancer cell motility
    • Sisci D, Aquila S, Middea E et al. Fibronectin and type IV collagen activate ERalpha AF-1 by c-Src pathway: Effect on breast cancer cell motility. Oncogene 2004; 23: 8920-8930.
    • (2004) Oncogene , vol.23 , pp. 8920-8930
    • Sisci, D.1    Aquila, S.2    Middea, E.3
  • 23
    • 33646157284 scopus 로고    scopus 로고
    • RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells
    • Cesarone G, Garofalo C, Abrams MT et al. RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells. J Cell Biochem 2006; 98: 440-450.
    • (2006) J Cell Biochem , vol.98 , pp. 440-450
    • Cesarone, G.1    Garofalo, C.2    Abrams, M.T.3
  • 24
    • 8544284095 scopus 로고    scopus 로고
    • Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer
    • Surmacz E, Bartucci M. Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer. J Exp Clin Cancer Res 2004; 23: 385-394.
    • (2004) J Exp Clin Cancer Res , vol.23 , pp. 385-394
    • Surmacz, E.1    Bartucci, M.2
  • 25
    • 0034788985 scopus 로고    scopus 로고
    • The IGF system and breast cancer
    • Sachdev D, Yee D. The IGF system and breast cancer. Endocr Relat Cancer 2001; 8: 197-209.
    • (2001) Endocr Relat Cancer , vol.8 , pp. 197-209
    • Sachdev, D.1    Yee, D.2
  • 26
    • 0037199956 scopus 로고    scopus 로고
    • Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor
    • Prisco M, Santini F, Baffa R et al. Nuclear translocation of insulin receptor substrate-1 by the simian virus 40 T antigen and the activated type 1 insulin-like growth factor receptor. J Biol Chem 2002; 277: 32078-32085.
    • (2002) J Biol Chem , vol.277 , pp. 32078-32085
    • Prisco, M.1    Santini, F.2    Baffa, R.3
  • 27
    • 0037338708 scopus 로고    scopus 로고
    • Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2
    • Sun H, Tu X, Prisco M et al. Insulin-like growth factor I receptor signaling and nuclear translocation of insulin receptor substrates 1 and 2. Mol Endocrinol 2003; 17: 472-486.
    • (2003) Mol Endocrinol , vol.17 , pp. 472-486
    • Sun, H.1    Tu, X.2    Prisco, M.3
  • 28
    • 0034526749 scopus 로고    scopus 로고
    • A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I
    • Martin MB, Franke TF, Stoica GE et al. A role for Akt in mediating the estrogenic functions of epidermal growth factor and insulin-like growth factor I. Endocrinology 2000; 141: 4503-4511.
    • (2000) Endocrinology , vol.141 , pp. 4503-4511
    • Martin, M.B.1    Franke, T.F.2    Stoica, G.E.3
  • 29
    • 33947493624 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells
    • Cascio S, Bartella V, Garofalo C et al. Insulin-like growth factor 1 differentially regulates estrogen receptor-dependent transcription at estrogen response element and AP-1 sites in breast cancer cells. J Biol Chem 2007; 282: 3498-3506.
    • (2007) J Biol Chem , vol.282 , pp. 3498-3506
    • Cascio, S.1    Bartella, V.2    Garofalo, C.3
  • 31
    • 0028886694 scopus 로고
    • Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
    • Kato S, Endoh H, Masuhiro Y et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995; 270: 1491-1494.
    • (1995) Science , vol.270 , pp. 1491-1494
    • Kato, S.1    Endoh, H.2    Masuhiro, Y.3
  • 32
    • 0029877913 scopus 로고    scopus 로고
    • Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
    • Bunone G, Briand PA, Miksicek RJ, Picard D. Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 1996; 15: 2174-2183.
    • (1996) EMBO J , vol.15 , pp. 2174-2183
    • Bunone, G.1    Briand, P.A.2    Miksicek, R.J.3    Picard, D.4
  • 33
    • 0031031824 scopus 로고    scopus 로고
    • Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells
    • Lee AV, Weng CN, Jackson JG, Yee D. Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. J Endocrinol 1997; 152: 39-47.
    • (1997) J Endocrinol , vol.152 , pp. 39-47
    • Lee, A.V.1    Weng, C.N.2    Jackson, J.G.3    Yee, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.