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Volumn 12, Issue 2, 2007, Pages 201-210

Genetic polymorphisms of the epidermal growth factor and related receptor in non-small cell lung cancer - A review of the literature

Author keywords

Epidermal growth factor; Epidermal growth factor receptor; Non small cell lung cancer; Polymorphism

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ERLOTINIB; GEFITINIB; PROTEIN TYROSINE KINASE INHIBITOR;

EID: 33847056277     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.12-2-201     Document Type: Review
Times cited : (74)

References (89)
  • 1
    • 19844373387 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: Looking to the future
    • Alberg AJ, Brock MV, Samet JM. Epidemiology of lung cancer: Looking to the future. J Clin Oncol 2005;23:3175-3185.
    • (2005) J Clin Oncol , vol.23 , pp. 3175-3185
    • Alberg, A.J.1    Brock, M.V.2    Samet, J.M.3
  • 2
    • 33644847618 scopus 로고    scopus 로고
    • Clinical cancer advances 2005: Major research advances in cancer treatment, prevention, and screening - a report from the American Society of Clinical Oncology
    • Herbst RS, Bajorin DF, Bleiberg H et al. Clinical cancer advances 2005: Major research advances in cancer treatment, prevention, and screening - a report from the American Society of Clinical Oncology. J Clin Oncol 2006;24:190-205.
    • (2006) J Clin Oncol , vol.24 , pp. 190-205
    • Herbst, R.S.1    Bajorin, D.F.2    Bleiberg, H.3
  • 3
    • 0032843811 scopus 로고    scopus 로고
    • Estimates of the worldwide mortality from 25 cancers in 1990
    • Pisani P, Parkin DM, Bray F et al. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999;83:870-873.
    • (1999) Int J Cancer , vol.83 , pp. 870-873
    • Pisani, P.1    Parkin, D.M.2    Bray, F.3
  • 4
    • 0001120212 scopus 로고
    • A descriptive model of the cigarette epidemic in developed countries
    • Lopez AD, Collishaw NE, Piha T. A descriptive model of the cigarette epidemic in developed countries. Tobacco Control 1994;3:242-247.
    • (1994) Tobacco Control , vol.3 , pp. 242-247
    • Lopez, A.D.1    Collishaw, N.E.2    Piha, T.3
  • 5
    • 0345872083 scopus 로고    scopus 로고
    • Multidisciplinary management of lung cancer
    • Spira A, Ettinger DS. Multidisciplinary management of lung cancer. N Engl J Med 2004;350:379-392.
    • (2004) N Engl J Med , vol.350 , pp. 379-392
    • Spira, A.1    Ettinger, D.S.2
  • 6
    • 0030776846 scopus 로고    scopus 로고
    • Implications of staging in lung cancer
    • s
    • Naruke T, Tsuchiya R, Kondo H et al. Implications of staging in lung cancer. Chest 1997;112:242s-248s.
    • (1997) Chest , vol.112
    • Naruke, T.1    Tsuchiya, R.2    Kondo, H.3
  • 7
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
    • Non-Small Cell Lung Cancer Collaborative Group
    • Non-Small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 1995;311:899-909.
    • (1995) BMJ , vol.311 , pp. 899-909
  • 8
    • 0021958679 scopus 로고
    • Autocrine growth factors and cancer
    • Sporn MB, Roberts AB. Autocrine growth factors and cancer. Nature 1985;313:745-747.
    • (1985) Nature , vol.313 , pp. 745-747
    • Sporn, M.B.1    Roberts, A.B.2
  • 9
    • 0026316096 scopus 로고
    • Growth factors and cancer
    • Aaronson SA. Growth factors and cancer. Science 1991;254:1146-1153.
    • (1991) Science , vol.254 , pp. 1146-1153
    • Aaronson, S.A.1
  • 11
    • 27844599703 scopus 로고    scopus 로고
    • Novel targeted therapies in the treatment of gastric and esophageal cancer
    • Tabernero J, Macarulla T, Ramos FJ et al. Novel targeted therapies in the treatment of gastric and esophageal cancer. Ann Oncol 2005;16:1740-1748.
    • (2005) Ann Oncol , vol.16 , pp. 1740-1748
    • Tabernero, J.1    Macarulla, T.2    Ramos, F.J.3
  • 12
    • 0028116305 scopus 로고
    • Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells
    • Fan Z, Lu Y, Wu X et al. Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells. J Biol Chem 1994;269:27595-27602.
    • (1994) J Biol Chem , vol.269 , pp. 27595-27602
    • Fan, Z.1    Lu, Y.2    Wu, X.3
  • 13
    • 12144287534 scopus 로고    scopus 로고
    • United States Food and Drug Administration drug approval summary: Gefitinib (ZD1839; Iressa) tablets
    • Cohen MH, Williams GA, Sridhara R et al. United States Food and Drug Administration drug approval summary: Gefitinib (ZD1839; Iressa) tablets. Clin Cancer Res 2004;10:1212-1218.
    • (2004) Clin Cancer Res , vol.10 , pp. 1212-1218
    • Cohen, M.H.1    Williams, G.A.2    Sridhara, R.3
  • 14
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd FA, Pereira JR, Ciuleanu T et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005;353:123-132.
    • (2005) N Engl J Med , vol.353 , pp. 123-132
    • Shepherd, F.A.1    Pereira, J.R.2    Ciuleanu, T.3
  • 15
    • 32944482229 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics in oncology therapeutic antibody development
    • Yan L, Beckman RA. Pharmacogenetics and pharmacogenomics in oncology therapeutic antibody development. Biotechniques 2005;39:565-568.
    • (2005) Biotechniques , vol.39 , pp. 565-568
    • Yan, L.1    Beckman, R.A.2
  • 16
    • 0035865322 scopus 로고    scopus 로고
    • International SNP Map Working Group: A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Sachidanandam R, Weissman D, Schmidt SC et al. International SNP Map Working Group: A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 2001;409:928-933.
    • (2001) Nature , vol.409 , pp. 928-933
    • Sachidanandam, R.1    Weissman, D.2    Schmidt, S.C.3
  • 17
    • 0036850208 scopus 로고    scopus 로고
    • Outcome in prostate cancer: Association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7
    • Medeiros RM, Morais A, Vasconcelos A et al. Outcome in prostate cancer: Association with endothelial nitric oxide synthase Glu-Asp298 polymorphism at exon 7. Clin Cancer Res 2002;8:3433-3437.
    • (2002) Clin Cancer Res , vol.8 , pp. 3433-3437
    • Medeiros, R.M.1    Morais, A.2    Vasconcelos, A.3
  • 18
    • 0042305238 scopus 로고    scopus 로고
    • Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: Glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome
    • Medeiros R, Pereira D, Afonso N et al. Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: Glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome. Int J Clin Oncol 2003;8:156-161.
    • (2003) Int J Clin Oncol , vol.8 , pp. 156-161
    • Medeiros, R.1    Pereira, D.2    Afonso, N.3
  • 19
    • 1542377512 scopus 로고    scopus 로고
    • Metabolic susceptibility genes and prostate cancer risk in a southern European population: The role of glutathione S-transferases GSTM1, GSTM3, and GSTT1 genetic polymorphisms
    • Medeiros R, Vasconcelos A, Costa S et al. Metabolic susceptibility genes and prostate cancer risk in a southern European population: The role of glutathione S-transferases GSTM1, GSTM3, and GSTT1 genetic polymorphisms. Prostate 2004;58:414-420.
    • (2004) Prostate , vol.58 , pp. 414-420
    • Medeiros, R.1    Vasconcelos, A.2    Costa, S.3
  • 20
    • 33847079409 scopus 로고    scopus 로고
    • CXCL12-3′ A polymorphism and lung cancer metastases protection: New perspectives in immunotherapy?
    • Coelho A, Calçada C, Catarino R et al. CXCL12-3′ A polymorphism and lung cancer metastases protection: New perspectives in immunotherapy? Cancer Immunol Immunother 2005;6:1-5.
    • (2005) Cancer Immunol Immunother , vol.6 , pp. 1-5
    • Coelho, A.1    Calçada, C.2    Catarino, R.3
  • 21
    • 2642570170 scopus 로고    scopus 로고
    • Moving towards individualized medicine with pharmacogenomics
    • Evans WE, Relling MV. Moving towards individualized medicine with pharmacogenomics. Nature 2004;429:464-468.
    • (2004) Nature , vol.429 , pp. 464-468
    • Evans, W.E.1    Relling, M.V.2
  • 22
    • 21344453004 scopus 로고    scopus 로고
    • Pharmacogenetics for individualized cancer chemotherapy
    • Efferth T, Volm M. Pharmacogenetics for individualized cancer chemotherapy. Pharmacol Ther 2005;107:155-176.
    • (2005) Pharmacol Ther , vol.107 , pp. 155-176
    • Efferth, T.1    Volm, M.2
  • 23
    • 33646414773 scopus 로고    scopus 로고
    • A functional polymorphism in the promoter region of leptin gene increases susceptibility for non-small cell lung cancer
    • Ribeiro R, Araújo AP, Coelho A et al. A functional polymorphism in the promoter region of leptin gene increases susceptibility for non-small cell lung cancer. Eur J Cancer 2006;42:1188-1193.
    • (2006) Eur J Cancer , vol.42 , pp. 1188-1193
    • Ribeiro, R.1    Araújo, A.P.2    Coelho, A.3
  • 24
    • 33644982287 scopus 로고    scopus 로고
    • Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy
    • Shepherd FA, Tsao MS. Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy. J Clin Oncol 2006;24:1219-1223.
    • (2006) J Clin Oncol , vol.24 , pp. 1219-1223
    • Shepherd, F.A.1    Tsao, M.S.2
  • 25
    • 0019305094 scopus 로고
    • Genetic analysis of epidermal growth factor action: Assignment of human epidermal growth factor receptor to chromosome 7
    • Davies RL, Grosse VA, Kucherlapati R et al. Genetic analysis of epidermal growth factor action: Assignment of human epidermal growth factor receptor to chromosome 7. Proc Natl Acad Sci U S A 1980;77:4188-4192.
    • (1980) Proc Natl Acad Sci U S A , vol.77 , pp. 4188-4192
    • Davies, R.L.1    Grosse, V.A.2    Kucherlapati, R.3
  • 26
    • 0023551286 scopus 로고
    • The human EGF receptor gene: Structure of the 110 kb locus and identification of sequences regulating its transcription
    • Haley J, Whittle N, Bennet P et al. The human EGF receptor gene: Structure of the 110 kb locus and identification of sequences regulating its transcription. Oncogene Res 1987;1:375-396.
    • (1987) Oncogene Res , vol.1 , pp. 375-396
    • Haley, J.1    Whittle, N.2    Bennet, P.3
  • 28
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signalling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA et al. The ErbB signalling network: Receptor heterodimerization in development and cancer. EMBO J 2000;19:3159-3167.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3
  • 29
    • 0037429779 scopus 로고    scopus 로고
    • The deaf and the dumb: The biology of ErbB-2 and ErbB-3
    • Citri A, Skaria KB, Yarden Y. The deaf and the dumb: The biology of ErbB-2 and ErbB-3. Exp Cell Res 2003;284:54-65.
    • (2003) Exp Cell Res , vol.284 , pp. 54-65
    • Citri, A.1    Skaria, K.B.2    Yarden, Y.3
  • 30
    • 3042665929 scopus 로고    scopus 로고
    • The biology of epidermal growth factor receptor in lung cancer
    • s
    • Scagliotti GV, Selvaggi G, Novello S et al. The biology of epidermal growth factor receptor in lung cancer. Clin Cancer Res 2004;10:4227s-4232s.
    • (2004) Clin Cancer Res , vol.10
    • Scagliotti, G.V.1    Selvaggi, G.2    Novello, S.3
  • 31
    • 1242329830 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: A promising target in solid tumours
    • Laskin JJ, Sandler AB. Epidermal growth factor receptor: A promising target in solid tumours. Cancer Treat Rev 2004;30:1-17.
    • (2004) Cancer Treat Rev , vol.30 , pp. 1-17
    • Laskin, J.J.1    Sandler, A.B.2
  • 32
    • 0032719534 scopus 로고    scopus 로고
    • Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
    • Akimoto T, Hunter NR, Buchmiller L et al. Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 1999;5:2884-2890.
    • (1999) Clin Cancer Res , vol.5 , pp. 2884-2890
    • Akimoto, T.1    Hunter, N.R.2    Buchmiller, L.3
  • 33
  • 34
    • 0030803735 scopus 로고    scopus 로고
    • Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck
    • Sheridan MT, O'Dwyer T, Seymour CB et al. Potential indicators of radiosensitivity in squamous cell carcinoma of the head and neck. Radiat Oncol Investig 1997;5:180-186.
    • (1997) Radiat Oncol Investig , vol.5 , pp. 180-186
    • Sheridan, M.T.1    O'Dwyer, T.2    Seymour, C.B.3
  • 35
    • 0030974096 scopus 로고    scopus 로고
    • Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases
    • Carraway KL 3rd, Weber JL, Unger MJ et al. Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases. Nature 1997;387:512-516.
    • (1997) Nature , vol.387 , pp. 512-516
    • Carraway 3rd, K.L.1    Weber, J.L.2    Unger, M.J.3
  • 36
    • 0030911331 scopus 로고    scopus 로고
    • Ligands for ErbB-family receptors encoded by a neuregulin-like gene
    • Chang H, Riese II DJ, Gilbert W et al. Ligands for ErbB-family receptors encoded by a neuregulin-like gene. Nature 1997;387:509-512.
    • (1997) Nature , vol.387 , pp. 509-512
    • Chang, H.1    Riese II, D.J.2    Gilbert, W.3
  • 37
    • 0033614356 scopus 로고    scopus 로고
    • Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
    • Harari D, Tzahar E, Romano J et al. Neuregulin-4: A novel growth factor that acts through the ErbB-4 receptor tyrosine kinase. Oncogene 1999;18:2681-2689.
    • (1999) Oncogene , vol.18 , pp. 2681-2689
    • Harari, D.1    Tzahar, E.2    Romano, J.3
  • 38
    • 12644279865 scopus 로고    scopus 로고
    • Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
    • Zhang D, Sliwkowski MX, Mark M et al. Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4. Proc Natl Acad Sci U S A 1997;94:9562-9567.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9562-9567
    • Zhang, D.1    Sliwkowski, M.X.2    Mark, M.3
  • 39
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ II, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998;20:41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stern, D.F.2
  • 40
    • 0030030072 scopus 로고    scopus 로고
    • ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer
    • Karunagaran D, Tzahar E, Beerli RR et al. ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: Implications for breast cancer. EMBO J 1996;15:254-264.
    • (1996) EMBO J , vol.15 , pp. 254-264
    • Karunagaran, D.1    Tzahar, E.2    Beerli, R.R.3
  • 41
    • 0033605560 scopus 로고    scopus 로고
    • ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
    • Worthylake R, Opresko LK, Wiley HS. ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J Biol Chem 1999;274:8865-8874.
    • (1999) J Biol Chem , vol.274 , pp. 8865-8874
    • Worthylake, R.1    Opresko, L.K.2    Wiley, H.S.3
  • 42
    • 0347386407 scopus 로고    scopus 로고
    • Signal events: Cell signal transduction and its inhibition in cancer
    • Rowinsky EK. Signal events: Cell signal transduction and its inhibition in cancer. The Oncologist 2003;8(suppl 3):5-17.
    • (2003) The Oncologist , vol.8 , Issue.SUPPL. 3 , pp. 5-17
    • Rowinsky, E.K.1
  • 43
    • 0034644539 scopus 로고    scopus 로고
    • Cell signalling by receptor tyrosine kinases
    • Schlessinger J. Cell signalling by receptor tyrosine kinases. Cell 2000;103:211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 44
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
    • Fukuoka M, Yano S, Giaccone G et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 2003;21:2237-2246.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 45
    • 4344646459 scopus 로고    scopus 로고
    • Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
    • Perez-Soler R, Chachoua A, Hammond L et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004;22:3238-3247.
    • (2004) J Clin Oncol , vol.22 , pp. 3238-3247
    • Perez-Soler, R.1    Chachoua, A.2    Hammond, L.3
  • 46
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 47
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 48
    • 27244451321 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutations and increase copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
    • Takano T, Ohe Y, Sakamoto H et al. Epidermal growth factor receptor gene mutations and increase copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005;23:6829-6837.
    • (2005) J Clin Oncol , vol.23 , pp. 6829-6837
    • Takano, T.1    Ohe, Y.2    Sakamoto, H.3
  • 49
    • 27244443759 scopus 로고    scopus 로고
    • Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group Study
    • Hirsch FR, Varella-Garcia M, McCoy J et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group Study. J Clin Oncol 2005;23:6838-6845.
    • (2005) J Clin Oncol , vol.23 , pp. 6838-6845
    • Hirsch, F.R.1    Varella-Garcia, M.2    McCoy, J.3
  • 50
    • 27244444360 scopus 로고    scopus 로고
    • Selecting patients for epidermal growth factor receptor inhibitor treatment: A FISH story or a tale of mutations?
    • Johnson BE, Jänne PA. Selecting patients for epidermal growth factor receptor inhibitor treatment: A FISH story or a tale of mutations? J Clin Oncol 2005;23:6813-6816.
    • (2005) J Clin Oncol , vol.23 , pp. 6813-6816
    • Johnson, B.E.1    Jänne, P.A.2
  • 51
    • 0026864473 scopus 로고
    • Two chromosome 7 dinucleotide repeat polymorphisms at gene loci epidermal growth factor receptor (EGFR) and pro α 2 (I) collagen (COL1A2)
    • Chi DD, Hing AV, Helms C et al. Two chromosome 7 dinucleotide repeat polymorphisms at gene loci epidermal growth factor receptor (EGFR) and pro α 2 (I) collagen (COL1A2). Hum Mol Genet 1992;1:135.
    • (1992) Hum Mol Genet , vol.1 , pp. 135
    • Chi, D.D.1    Hing, A.V.2    Helms, C.3
  • 52
    • 0030990477 scopus 로고    scopus 로고
    • Competitive-differential polymerase chain reaction for gene dosage estimation of erbB-1 (egfr), erbB-2, and erbB-3 oncogenes
    • Roetger A, Brandt B, Barnekow A. Competitive-differential polymerase chain reaction for gene dosage estimation of erbB-1 (egfr), erbB-2, and erbB-3 oncogenes. DNA Cell Biol 1997;16:443-448.
    • (1997) DNA Cell Biol , vol.16 , pp. 443-448
    • Roetger, A.1    Brandt, B.2    Barnekow, A.3
  • 53
    • 0033914059 scopus 로고    scopus 로고
    • Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations - a link between genetics and epigenetics
    • Gebhardt F, Bürger H, Brandt B. Modulation of EGFR gene transcription by secondary structures, a polymorphic repetitive sequence and mutations - a link between genetics and epigenetics. Histol Histopathol 2000;15:929-936.
    • (2000) Histol Histopathol , vol.15 , pp. 929-936
    • Gebhardt, F.1    Bürger, H.2    Brandt, B.3
  • 54
    • 0040886242 scopus 로고    scopus 로고
    • Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1
    • Gebhardt F, Zanker KS, Brandt B. Modulation of epidermal growth factor receptor gene transcription by a polymorphic dinucleotide repeat in intron 1. J Biol Chem 1999;274:13176-13180.
    • (1999) J Biol Chem , vol.274 , pp. 13176-13180
    • Gebhardt, F.1    Zanker, K.S.2    Brandt, B.3
  • 55
    • 0034652578 scopus 로고    scopus 로고
    • Length and loss of heterozygosity of an intron 1 polymorphic sequence of EGFR is related to cytogenetic alterations and epithelial growth factor receptor expression
    • Buerger H, Gebhardt F, Schmidt H et al. Length and loss of heterozygosity of an intron 1 polymorphic sequence of EGFR is related to cytogenetic alterations and epithelial growth factor receptor expression. Cancer Res 2000;60:854-857.
    • (2000) Cancer Res , vol.60 , pp. 854-857
    • Buerger, H.1    Gebhardt, F.2    Schmidt, H.3
  • 56
    • 0037339858 scopus 로고    scopus 로고
    • Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism
    • Liu W, Innocenti F, Chen P et al. Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism. Clin Cancer Res 2003;9:1009-1012.
    • (2003) Clin Cancer Res , vol.9 , pp. 1009-1012
    • Liu, W.1    Innocenti, F.2    Chen, P.3
  • 57
    • 0023082137 scopus 로고
    • Receptors for epidermal growth factor and other polypeptide mitogens
    • Carpenter G. Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem 1987;56:881-914.
    • (1987) Annu Rev Biochem , vol.56 , pp. 881-914
    • Carpenter, G.1
  • 58
    • 10844264628 scopus 로고    scopus 로고
    • An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors
    • Amador ML, Oppenheimer D, Perea S et al. An epidermal growth factor receptor intron 1 polymorphism mediates response to epidermal growth factor receptor inhibitors. Cancer Res 2004;64:9139-9143.
    • (2004) Cancer Res , vol.64 , pp. 9139-9143
    • Amador, M.L.1    Oppenheimer, D.2    Perea, S.3
  • 59
    • 33846979362 scopus 로고    scopus 로고
    • EGFR dinucleotide repeat polymorphism as a prognostic indicator in non-small cell lung cancer
    • Dubey S, Stephenson P, Levy DE et al. EGFR dinucleotide repeat polymorphism as a prognostic indicator in non-small cell lung cancer. J Thorac Oncol 2006;1:406-412.
    • (2006) J Thorac Oncol , vol.1 , pp. 406-412
    • Dubey, S.1    Stephenson, P.2    Levy, D.E.3
  • 60
    • 0034718966 scopus 로고    scopus 로고
    • A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small cell lung cancer
    • Keller SM, Adak S, Wagner H et al. A randomized trial of postoperative adjuvant therapy in patients with completely resected stage II or IIIA non-small cell lung cancer. N Engl J Med 2000;343:1217-1222.
    • (2000) N Engl J Med , vol.343 , pp. 1217-1222
    • Keller, S.M.1    Adak, S.2    Wagner, H.3
  • 61
    • 33847016236 scopus 로고    scopus 로고
    • A prognostic and/or predictive marker
    • Hirsch FR. EGFR. A prognostic and/or predictive marker? J Thorac Oncol 2006;1:395-397.
    • (2006) J Thorac Oncol , vol.1 , pp. 395-397
    • Hirsch, F.E.1
  • 62
    • 0345422664 scopus 로고
    • Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene
    • Ishii S, Xu YH, Stratton RH et al. Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene. Proc Natl Acad Sci U S A 1985;82:4920-4924.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 4920-4924
    • Ishii, S.1    Xu, Y.H.2    Stratton, R.H.3
  • 63
    • 0023905447 scopus 로고
    • Epidermal growth factor receptor gene promoter: Deletion analysis and identification of nuclear protein binding sites
    • Johnson AC, Ishii S, JinnoY et al. Epidermal growth factor receptor gene promoter: Deletion analysis and identification of nuclear protein binding sites. J Biol Chem 1988;263:5693-5699.
    • (1988) J Biol Chem , vol.263 , pp. 5693-5699
    • Johnson, A.C.1    Ishii, S.2    JinnoY3
  • 64
    • 0020349339 scopus 로고
    • Deletion mapping of DNA regions required for SV40 early region promoter function in vivo
    • Fromm M, Berg P. Deletion mapping of DNA regions required for SV40 early region promoter function in vivo. J Mol Appl Genet 1982;1:457-481.
    • (1982) J Mol Appl Genet , vol.1 , pp. 457-481
    • Fromm, M.1    Berg, P.2
  • 65
    • 0022587320 scopus 로고
    • Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter
    • Dynan WS, Sazer S, Tijian R et al. Transcription factor Sp1 recognizes a DNA sequence in the mouse dihydrofolate reductase promoter. Nature 1986;319:246-248.
    • (1986) Nature , vol.319 , pp. 246-248
    • Dynan, W.S.1    Sazer, S.2    Tijian, R.3
  • 66
    • 0031755628 scopus 로고    scopus 로고
    • The promyelocytic leukaemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter
    • Vallian S, Chin KV, Chang KS. The promyelocytic leukaemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter. Mol Cell Biol 1998;18:7147-7156.
    • (1998) Mol Cell Biol , vol.18 , pp. 7147-7156
    • Vallian, S.1    Chin, K.V.2    Chang, K.S.3
  • 67
    • 0023916702 scopus 로고
    • Epidermal growth factor (EGF) receptor gene transcription: Requirement for Sp1 and an EGF receptor-specific factor
    • Kageyama R, Merlino GT, Pastan I. Epidermal growth factor (EGF) receptor gene transcription: Requirement for Sp1 and an EGF receptor-specific factor. J Biol Chem 1988;263:6329-6336.
    • (1988) J Biol Chem , vol.263 , pp. 6329-6336
    • Kageyama, R.1    Merlino, G.T.2    Pastan, I.3
  • 68
    • 0027338196 scopus 로고
    • T3 receptor suppression of Sp1-dependent transcription from the epidermal growth factor receptor promoter via overlapping DNA-binding sites
    • Xu J, Thompson KL, Shephard LB et al. T3 receptor suppression of Sp1-dependent transcription from the epidermal growth factor receptor promoter via overlapping DNA-binding sites. J Biol Chem 1993;268:16065-16073.
    • (1993) J Biol Chem , vol.268 , pp. 16065-16073
    • Xu, J.1    Thompson, K.L.2    Shephard, L.B.3
  • 69
    • 85047696724 scopus 로고    scopus 로고
    • Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells
    • Grinstein E, Jundt F, Weinert I et al. Sp1 as G1 cell cycle phase specific transcription factor in epithelial cells. Oncogene 2002;21:1485-1492.
    • (2002) Oncogene , vol.21 , pp. 1485-1492
    • Grinstein, E.1    Jundt, F.2    Weinert, I.3
  • 70
    • 11244319884 scopus 로고    scopus 로고
    • A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter
    • Liu W, Innocenti F, Wu MH et al. A functional common polymorphism in a Sp1 recognition site of the epidermal growth factor receptor gene promoter. Cancer Res 2005;65:46-53.
    • (2005) Cancer Res , vol.65 , pp. 46-53
    • Liu, W.1    Innocenti, F.2    Wu, M.H.3
  • 71
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004;101:13306-13311.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 72
    • 11144333540 scopus 로고    scopus 로고
    • Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer
    • Lee JW, Soung YH, Kim SY et al. Absence of EGFR mutation in the kinase domain in common human cancers besides non-small cell lung cancer. Int J Cancer 2005;113:510-511.
    • (2005) Int J Cancer , vol.113 , pp. 510-511
    • Lee, J.W.1    Soung, Y.H.2    Kim, S.Y.3
  • 73
    • 2942722368 scopus 로고    scopus 로고
    • Selecting the right patient for tumor therapy
    • Arteaga CL. Selecting the right patient for tumor therapy. Nat Med 2004;10:577-578.
    • (2004) Nat Med , vol.10 , pp. 577-578
    • Arteaga, C.L.1
  • 74
    • 0025146497 scopus 로고
    • The epidermal growth factor: A review of structural and functional relationships in the normal organism and in cancer cells
    • Laurence DJ, Gusterson BA. The epidermal growth factor: A review of structural and functional relationships in the normal organism and in cancer cells. Tumor Biol 1990;11:229-261.
    • (1990) Tumor Biol , vol.11 , pp. 229-261
    • Laurence, D.J.1    Gusterson, B.A.2
  • 75
    • 0025321157 scopus 로고
    • Epidermal growth factor
    • Carpenter G, Cohen S. Epidermal growth factor. J Biol Chem 1990;265:7709-7712.
    • (1990) J Biol Chem , vol.265 , pp. 7709-7712
    • Carpenter, G.1    Cohen, S.2
  • 76
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon DS, Brandt R, Ciardello F et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232.
    • (1995) Crit Rev Oncol Hematol , vol.19 , pp. 183-232
    • Salomon, D.S.1    Brandt, R.2    Ciardello, F.3
  • 77
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
    • Moulder SL, Yakes FM, Muthuswamy SK et al. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res 2001;61:8887-8895.
    • (2001) Cancer Res , vol.61 , pp. 8887-8895
    • Moulder, S.L.1    Yakes, F.M.2    Muthuswamy, S.K.3
  • 78
    • 1642421130 scopus 로고    scopus 로고
    • Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment
    • Normanno N, Bianco C, De Luca A et al. Target-based agents against ErbB receptors and their ligands: A novel approach to cancer treatment. Endocr Relat Cancer 2003;10:1-21.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 1-21
    • Normanno, N.1    Bianco, C.2    De Luca, A.3
  • 79
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signalling in cancer
    • Normanno N, De Luca A, Bianco C et al. Epidermal growth factor receptor (EGFR) signalling in cancer. Gene 2006;366:2-16.
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1    De Luca, A.2    Bianco, C.3
  • 80
    • 0037006414 scopus 로고    scopus 로고
    • Association between functional polymorphism in EGF gene and malignant melanoma
    • Shahbazi M, Pravica V, Nasreen N et al. Association between functional polymorphism in EGF gene and malignant melanoma. Lancet 2002;359:397-401.
    • (2002) Lancet , vol.359 , pp. 397-401
    • Shahbazi, M.1    Pravica, V.2    Nasreen, N.3
  • 81
    • 0028891810 scopus 로고    scopus 로고
    • Mackie RM, Aitchison T, Sirel JM et al. Prognostic models for subgroups of melanoma patients from the Scottish Melanoma Group database 1979-86, and their subsequent validation. Br J Cancer 1995;71:173-176.
    • Mackie RM, Aitchison T, Sirel JM et al. Prognostic models for subgroups of melanoma patients from the Scottish Melanoma Group database 1979-86, and their subsequent validation. Br J Cancer 1995;71:173-176.
  • 82
    • 0142117188 scopus 로고    scopus 로고
    • EGF +61 gene polymorphism and susceptibility to and prognostic markers in cutaneous malignant melanoma
    • McCarron SL, Bateman AC, Theaker JM et al. EGF +61 gene polymorphism and susceptibility to and prognostic markers in cutaneous malignant melanoma. Int J Cancer 2003;107:673-675.
    • (2003) Int J Cancer , vol.107 , pp. 673-675
    • McCarron, S.L.1    Bateman, A.C.2    Theaker, J.M.3
  • 83
    • 4644319990 scopus 로고    scopus 로고
    • EGF gene polymorphism and the risk of incident primary melanoma
    • Amend KL, Elder JT, Tomsho LP et al. EGF gene polymorphism and the risk of incident primary melanoma. Cancer Res 2004;64:2668-2672.
    • (2004) Cancer Res , vol.64 , pp. 2668-2672
    • Amend, K.L.1    Elder, J.T.2    Tomsho, L.P.3
  • 84
    • 4644371663 scopus 로고    scopus 로고
    • EGF polymorphism and risk of melanocytic neoplasia
    • James MR, Hayward NK, Dumenil T et al. EGF polymorphism and risk of melanocytic neoplasia. J Invest Dermatol 2004;123:760-762.
    • (2004) J Invest Dermatol , vol.123 , pp. 760-762
    • James, M.R.1    Hayward, N.K.2    Dumenil, T.3
  • 85
    • 4644338277 scopus 로고    scopus 로고
    • The relationship between the epidermal growth factor (EGF) 5′UTR variant A61G, and melanoma/nevus susceptibility
    • Randerson-Moor SL, Gaut R, Turner F. The relationship between the epidermal growth factor (EGF) 5′UTR variant A61G, and melanoma/nevus susceptibility. J Invest Dermatol 2004;123:755-759.
    • (2004) J Invest Dermatol , vol.123 , pp. 755-759
    • Randerson-Moor, S.L.1    Gaut, R.2    Turner, F.3
  • 86
    • 4644304007 scopus 로고    scopus 로고
    • Epidermal growth factor gene polymorphism and development of cutaneous melanoma
    • Howell WM. Epidermal growth factor gene polymorphism and development of cutaneous melanoma. J Invest Dermatol 2004;123:xx-xxi.
    • (2004) J Invest Dermatol , vol.123
    • Howell, W.M.1
  • 87
    • 1242316180 scopus 로고    scopus 로고
    • A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease
    • Bhowmick DA, Zhuang Z, Wait SD et al. A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease. Cancer Res 2004;64:1220-1223.
    • (2004) Cancer Res , vol.64 , pp. 1220-1223
    • Bhowmick, D.A.1    Zhuang, Z.2    Wait, S.D.3
  • 88
    • 21044442984 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the 5′ untranslated region of the EGF gene is associated with occurrence and malignant progression of gastric cancer
    • Hamai Y, Matsumura S, Matsusaki K et al. A single nucleotide polymorphism in the 5′ untranslated region of the EGF gene is associated with occurrence and malignant progression of gastric cancer. Pathobiology 2005;72:133-138.
    • (2005) Pathobiology , vol.72 , pp. 133-138
    • Hamai, Y.1    Matsumura, S.2    Matsusaki, K.3
  • 89
    • 26444475950 scopus 로고    scopus 로고
    • No association between EGF gene polymorphism and gastric cancer
    • Goto Y, Ando T, Goto H et al. No association between EGF gene polymorphism and gastric cancer. Cancer Epidemiol Biomarkers Prev 2005;14:2454-2456.
    • (2005) Cancer Epidemiol Biomarkers Prev , vol.14 , pp. 2454-2456
    • Goto, Y.1    Ando, T.2    Goto, H.3


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