Mechanistic study on the biological effects of silver and gold nanoparticles in Caco-2 cells - Induction of the Nrf2/HO-1 pathway by high concentrations of silver nanoparticles

Toxicology Letters

Volumn 224, Issue 1, 2014, Pages 73-83

  Aueviriyavit, Sasitorn ^a   Phummiratch, Duangkamol ^a   Maniratanachote, Rawiwan ^a  

^a NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Caco 2 cells; Gastrointestinal system; Gold nanoparticles; Heme oxygenase 1; Nrf2; Silver nanoparticles

Indexed keywords

GLUTATHIONE; GOLD NANOPARTICLE; HEME OXYGENASE 1; SILVER NANOPARTICLE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

2′,7′-DICHLOROFLUORESCEIN; 3-(4,5-DIMETHYL-2-THIAZOLYL)-2,5-DIPHENYL-2H-TETRAZOLIUM BROMIDE; 3-MORPHOLINOSYDNONIMINE HYDROCHLORIDE; 5-THIO-2-NITROBENZOIC ACID; AGNPS; ANTIOXIDANT-RESPONSIVE ELEMENT; ARE; AUNPS; CACO-2 CELLS; CM; COMPLETE CULTURE MEDIA; DCF; DLS; DYNAMIC LIGHT SCATTERING; GAPDH; GASTROINTESTINAL SYSTEM; GASTROINTESTINAL TRACT; GI; GLUTATHIONE; GLUTATHIONE S-TRANSFERASE P1; GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE; GOLD NANOPARTICLES; GSH; GSTP1; HEME OXYGENASE-1; HO-1; KEAP1; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; MAPKS; MITOGEN-ACTIVATED PROTEIN KINASE C; MRP1; MTT; MULTIDRUG RESISTANCE PROTEIN; N-ACETYLCYSTEINE; NAC; NANOPARTICLES; NPS; NRF2; NUCLEAR FACTOR (ERYTHROID-DERIVED 2)-LIKE 2; PBS; PHOSPHATE BUFFERED SALINE; QRT-PCR; QUANTITATIVE REAL TIME REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; ROS; SILVER NANOPARTICLES; SIN-1; TEM; TETRAMETHYLRHODAMINE ETHYL ESTER; TMRE; TNB; TRANSMISSION ELECTRON MICROSCOPY; UDP GLUCURONOSYLTRANSFERASE 1A1; UGT1A1;

ACETYLCYSTEINE; CACO-2 CELLS; GENE EXPRESSION REGULATION; GOLD; HEME OXYGENASE-1; HUMANS; METAL NANOPARTICLES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; SILVER;

EID: 84887558723     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.09.020     Document Type: Article

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