메뉴 건너뛰기




Volumn 53, Issue 1, 2009, Pages 52-62

Review of health safety aspects of nanotechnologies in food production

Author keywords

Detection; Exposure; Food; Kinetics; Nanoparticles; Nanotechnology; Oral; Risk assessment; Toxicology

Indexed keywords

COPPER; LIPOSOME; METAL; METAL OXIDE; NANOLIPOSOME; NANOPARTICLE; POLYMER; SILVER; TITANIUM DIOXIDE; UNCLASSIFIED DRUG; ZINC OXIDE;

EID: 59049101808     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2008.10.008     Document Type: Article
Times cited : (648)

References (87)
  • 1
    • 0023578342 scopus 로고
    • Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small-intestine
    • Aprahamian M., Michel C., Humbert W., Devissaguet J.P., and Damge C. Transmucosal passage of polyalkylcyanoacrylate nanocapsules as a new drug carrier in the small-intestine. Biology of the Cell 61 1-2 (1987) 69-76
    • (1987) Biology of the Cell , vol.61 , Issue.1-2 , pp. 69-76
    • Aprahamian, M.1    Michel, C.2    Humbert, W.3    Devissaguet, J.P.4    Damge, C.5
  • 5
    • 33144477406 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials, part V: role of dissolution in biological fate and effects of nanoscale particles
    • Borm P., Klaessig F.C., Landry T.D., Moudgil B., Pauluhn J., Thomas K., Trottier R., and Wood S. Research strategies for safety evaluation of nanomaterials, part V: role of dissolution in biological fate and effects of nanoscale particles. Toxicol. Sci. 90 1 (2006) 23-32
    • (2006) Toxicol. Sci. , vol.90 , Issue.1 , pp. 23-32
    • Borm, P.1    Klaessig, F.C.2    Landry, T.D.3    Moudgil, B.4    Pauluhn, J.5    Thomas, K.6    Trottier, R.7    Wood, S.8
  • 6
    • 6344229772 scopus 로고    scopus 로고
    • Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery
    • Borm P.J.A., and Kreyling W. Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery. Journal of Nanoscience and Nanotechnology 4 5 (2004) 521-531
    • (2004) Journal of Nanoscience and Nanotechnology , vol.4 , Issue.5 , pp. 521-531
    • Borm, P.J.A.1    Kreyling, W.2
  • 7
    • 0029776736 scopus 로고    scopus 로고
    • The effect of size on uptake of orally administered latex microparticles in the small intestine and transport to mesenteric lymph nodes
    • Carr K.E., Hazzard R.A., Reid S., and Hodges G.M. The effect of size on uptake of orally administered latex microparticles in the small intestine and transport to mesenteric lymph nodes. Pharm. Res. 13 8 (1996) 1205-1209
    • (1996) Pharm. Res. , vol.13 , Issue.8 , pp. 1205-1209
    • Carr, K.E.1    Hazzard, R.A.2    Reid, S.3    Hodges, G.M.4
  • 9
    • 53149110880 scopus 로고    scopus 로고
    • Nanotechnology Regulation-evelopments in the United Kingdom
    • Hodge G.A., Bowman D.M., and Ludlow K. (Eds), Edward Elgar, Cheltenham
    • Chaudhry Q., George C., and Watkins R. Nanotechnology Regulation-evelopments in the United Kingdom. In: Hodge G.A., Bowman D.M., and Ludlow K. (Eds). New Global Frontiers in Regulation: The Age of Nanotechnology (2007), Edward Elgar, Cheltenham 212-238
    • (2007) New Global Frontiers in Regulation: The Age of Nanotechnology , pp. 212-238
    • Chaudhry, Q.1    George, C.2    Watkins, R.3
  • 11
    • 33645786789 scopus 로고    scopus 로고
    • Nanotechnology in nutraceuticals and functional foods
    • Chen H.D., Weiss J.C., and Shahidi F. Nanotechnology in nutraceuticals and functional foods. Food Technology 60 3 (2006) 30
    • (2006) Food Technology , vol.60 , Issue.3 , pp. 30
    • Chen, H.D.1    Weiss, J.C.2    Shahidi, F.3
  • 15
    • 39649115201 scopus 로고    scopus 로고
    • Particle size-dependent organ distribution of gold nanoparticles after intravenous administration
    • De Jong W.H., Hagens W.I., Krystek P., Burger M.C., Sips A.J., and Geertsma R.E. Particle size-dependent organ distribution of gold nanoparticles after intravenous administration. Biomaterials 29 12 (2008) 1912-1919
    • (2008) Biomaterials , vol.29 , Issue.12 , pp. 1912-1919
    • De Jong, W.H.1    Hagens, W.I.2    Krystek, P.3    Burger, M.C.4    Sips, A.J.5    Geertsma, R.E.6
  • 16
    • 33751253462 scopus 로고    scopus 로고
    • Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach
    • des Rieux A., Fievez V., Garinot M., Schneider Y.J., and Preat V. Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J. Control. Release 116 1 (2006) 1-27
    • (2006) J. Control. Release , vol.116 , Issue.1 , pp. 1-27
    • des Rieux, A.1    Fievez, V.2    Garinot, M.3    Schneider, Y.J.4    Preat, V.5
  • 17
    • 0036829042 scopus 로고    scopus 로고
    • Colloidosomes: Selectively permeable capsules composed of colloidal particles
    • Dinsmore A. Colloidosomes: Selectively permeable capsules composed of colloidal particles. Science 298 5595 (2002) 1006-1009
    • (2002) Science , vol.298 , Issue.5595 , pp. 1006-1009
    • Dinsmore, A.1
  • 18
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia M. Immunological properties of engineered nanomaterials. Nature nanotechnology 2 8 (2007) 469-478
    • (2007) Nature nanotechnology , vol.2 , Issue.8 , pp. 469-478
    • Dobrovolskaia, M.1
  • 19
    • 85043355822 scopus 로고    scopus 로고
    • Approaches to the toxicological testing of particles
    • Donaldson K., and Borm P.J.A. (Eds), CRC press Taylor and Francis group, London
    • Donaldson K., Faus S., Borm P.J.A., and Stone V. Approaches to the toxicological testing of particles. In: Donaldson K., and Borm P.J.A. (Eds). Particle Toxicology (2007), CRC press Taylor and Francis group, London 299-316
    • (2007) Particle Toxicology , pp. 299-316
    • Donaldson, K.1    Faus, S.2    Borm, P.J.A.3    Stone, V.4
  • 20
    • 41649106948 scopus 로고    scopus 로고
    • The Janus faces of nanoparticles
    • Donaldson K., and Seaton A. The Janus faces of nanoparticles. J. Nanosci. Nanotechnol. 7 12 (2007) 4607-4611
    • (2007) J. Nanosci. Nanotechnol. , vol.7 , Issue.12 , pp. 4607-4611
    • Donaldson, K.1    Seaton, A.2
  • 22
    • 59049096400 scopus 로고    scopus 로고
    • Communication from the Commission-Towards a European strategy for nanotechnology, 2004. Luxembourg: Office for Official Publications of the European Communities 2004, pp. 24 ISBN 92-894-7686-9 (17.6 × 25 cm).
    • Communication from the Commission-Towards a European strategy for nanotechnology, 2004. Luxembourg: Office for Official Publications of the European Communities 2004, pp. 24 ISBN 92-894-7686-9 (17.6 × 25 cm).
  • 23
    • 59049102831 scopus 로고    scopus 로고
    • FAO/WHO, 1997. Food consumption and exposure assessment of chemicals, Report of a FAO/WHO Consultation, 10-14 February 1997, Geneva, Document WHO/FSF/FOS/97.5, WHO, Geneva.
    • FAO/WHO, 1997. Food consumption and exposure assessment of chemicals, Report of a FAO/WHO Consultation, 10-14 February 1997, Geneva, Document WHO/FSF/FOS/97.5, WHO, Geneva.
  • 24
    • 21744458087 scopus 로고    scopus 로고
    • Nanoparticle uptake by the oral route: Fulfilling its potential?
    • Florence A.T. Nanoparticle uptake by the oral route: Fulfilling its potential?. Drug Discovery Today: Technologies 2 1 (2005) 75-81
    • (2005) Drug Discovery Today: Technologies , vol.2 , Issue.1 , pp. 75-81
    • Florence, A.T.1
  • 26
    • 1142273201 scopus 로고    scopus 로고
    • The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery
    • Gabor F., Bogner E., Weissenboeck A., and Wirth M. The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery. Adv. Drug Deliv. Rev. 56 4 (2004) 459-480
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , Issue.4 , pp. 459-480
    • Gabor, F.1    Bogner, E.2    Weissenboeck, A.3    Wirth, M.4
  • 27
    • 67649491631 scopus 로고    scopus 로고
    • Regulation of nanotechnology-within REACH?
    • Gergely A. Regulation of nanotechnology-within REACH?. Nano Now February (2007) 44-46
    • (2007) Nano Now February , pp. 44-46
    • Gergely, A.1
  • 29
    • 0028363311 scopus 로고
    • Characterization of the adsorption of conjugated and unconjugated bile-acids to insoluble, amorphous calcium-phosphate
    • Govers M., Termont D., Vanaken G.A., and Vandermeer R. Characterization of the adsorption of conjugated and unconjugated bile-acids to insoluble, amorphous calcium-phosphate. Journal of Lipid Research 35 5 (1994) 741-748
    • (1994) Journal of Lipid Research , vol.35 , Issue.5 , pp. 741-748
    • Govers, M.1    Termont, D.2    Vanaken, G.A.3    Vandermeer, R.4
  • 31
    • 36048947290 scopus 로고    scopus 로고
    • What do we (need to) know about the kinetic properties of nanoparticles in the body?
    • Hagens W.I., Oomen A.G., de Jong W.H., Cassee F.R., and Sips A.J. What do we (need to) know about the kinetic properties of nanoparticles in the body?. Regul. Toxicol. Pharmacol. 49 3 (2007) 217-229
    • (2007) Regul. Toxicol. Pharmacol. , vol.49 , Issue.3 , pp. 217-229
    • Hagens, W.I.1    Oomen, A.G.2    de Jong, W.H.3    Cassee, F.R.4    Sips, A.J.5
  • 32
    • 32044451341 scopus 로고    scopus 로고
    • A toxicologic review of quantum dots: toxicity depends on physico-chemical and environmental factors
    • Hardman R. A toxicologic review of quantum dots: toxicity depends on physico-chemical and environmental factors. Environ Health Perspect 114 2 (2006) 165-172
    • (2006) Environ Health Perspect , vol.114 , Issue.2 , pp. 165-172
    • Hardman, R.1
  • 33
    • 59049102563 scopus 로고    scopus 로고
    • Health Council Netherlands. 2006. Health significance of nanotechnologies. The Hague: Health Council of the Netherlands, Publication No. 2006/06.
    • Health Council Netherlands. 2006. Health significance of nanotechnologies. The Hague: Health Council of the Netherlands, Publication No. 2006/06.
  • 35
    • 0028235218 scopus 로고
    • Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles
    • Hillery A.M., Jani P.U., and Florence A.T. Comparative, quantitative study of lymphoid and non-lymphoid uptake of 60 nm polystyrene particles. J. Drug Target. 2 2 (1994) 151-156
    • (1994) J. Drug Target. , vol.2 , Issue.2 , pp. 151-156
    • Hillery, A.M.1    Jani, P.U.2    Florence, A.T.3
  • 36
    • 0035206137 scopus 로고    scopus 로고
    • Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles
    • Hillyer J.F., and Albrecht R.M. Gastrointestinal persorption and tissue distribution of differently sized colloidal gold nanoparticles. Journal of Pharmaceutical Sciences 90 12 (2001) 1927-1936
    • (2001) Journal of Pharmaceutical Sciences , vol.90 , Issue.12 , pp. 1927-1936
    • Hillyer, J.F.1    Albrecht, R.M.2
  • 37
    • 77949913224 scopus 로고    scopus 로고
    • Hodge, G., Bowman, D., Ludlow, K., 2007. New Global Frontiers in Regulation: In: The Age of Nanotechnology. Edward Elgar, Cheltenham.
    • Hodge, G., Bowman, D., Ludlow, K., 2007. New Global Frontiers in Regulation: In: The Age of Nanotechnology. Edward Elgar, Cheltenham.
  • 39
    • 33646940975 scopus 로고    scopus 로고
    • Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability
    • Hong S.P., Leroueil P.R., Janus E.K., Peters J.L., Kober M.M., Islam M.T., Orr B.G., Baker J.R., and Holl M.M.B. Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjugate Chemistry 17 3 (2006) 728-734
    • (2006) Bioconjugate Chemistry , vol.17 , Issue.3 , pp. 728-734
    • Hong, S.P.1    Leroueil, P.R.2    Janus, E.K.3    Peters, J.L.4    Kober, M.M.5    Islam, M.T.6    Orr, B.G.7    Baker, J.R.8    Holl, M.M.B.9
  • 41
    • 0025674686 scopus 로고
    • Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency
    • Jani P., Halbert G.W., Langridge J., and Florence A.T. Nanoparticle uptake by the rat gastrointestinal mucosa: quantitation and particle size dependency. J. Pharm. Pharmacol. 42 12 (1990) 821-826
    • (1990) J. Pharm. Pharmacol. , vol.42 , Issue.12 , pp. 821-826
    • Jani, P.1    Halbert, G.W.2    Langridge, J.3    Florence, A.T.4
  • 42
    • 13544255508 scopus 로고    scopus 로고
    • A subchronic toxicity study of elemental Nano-Se in Sprague-Dawley rats
    • Jia X., Li N., and Chen J. A subchronic toxicity study of elemental Nano-Se in Sprague-Dawley rats. Life Sci. 76 17 (2005) 1989-2003
    • (2005) Life Sci. , vol.76 , Issue.17 , pp. 1989-2003
    • Jia, X.1    Li, N.2    Chen, J.3
  • 43
    • 33751562849 scopus 로고    scopus 로고
    • Polymer genomics: An insight into pharmacology and toxicology of nanomedicines
    • Kabanov A.V. Polymer genomics: An insight into pharmacology and toxicology of nanomedicines. Advanced Drug Delivery Reviews 58 15 (2006) 1597-1621
    • (2006) Advanced Drug Delivery Reviews , vol.58 , Issue.15 , pp. 1597-1621
    • Kabanov, A.V.1
  • 45
    • 0346256860 scopus 로고    scopus 로고
    • Advances in biomaterials, drug delivery, and bionanotechnology. American Institute of Chemical Engineers
    • Langer R. Advances in biomaterials, drug delivery, and bionanotechnology. American Institute of Chemical Engineers. AIChE Journal 49 12 (2003) 2990-3006
    • (2003) AIChE Journal , vol.49 , Issue.12 , pp. 2990-3006
    • Langer, R.1
  • 47
    • 33847256524 scopus 로고    scopus 로고
    • A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes
    • Letchford K., and Burt H. A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes. Eur. J. Pharm. Biopharm. 65 3 (2007) 259-269
    • (2007) Eur. J. Pharm. Biopharm. , vol.65 , Issue.3 , pp. 259-269
    • Letchford, K.1    Burt, H.2
  • 48
    • 38849111818 scopus 로고    scopus 로고
    • Cytotoxicity of nanoparticles
    • Lewinski N., Colvin V., and Drezek R. Cytotoxicity of nanoparticles. Small 4 1 (2008) 26-49
    • (2008) Small , vol.4 , Issue.1 , pp. 26-49
    • Lewinski, N.1    Colvin, V.2    Drezek, R.3
  • 49
    • 0036183331 scopus 로고    scopus 로고
    • Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease
    • Lomer M.C., Thompson R.P., and Powell J.J. Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease. Proc. Nutr. Soc. 61 1 (2002) 123-130
    • (2002) Proc. Nutr. Soc. , vol.61 , Issue.1 , pp. 123-130
    • Lomer, M.C.1    Thompson, R.P.2    Powell, J.J.3
  • 50
    • 53649090334 scopus 로고    scopus 로고
    • Luykx, D., Peters, R., Ruth van, S., Bouwmeester, H., 2008. A review of analytical methods for the identification and characterisation of nano delivery systems in food. Journal of Agricultural and Food Chemistry, ASAP Article, 10.1021/jf8013926.
    • Luykx, D., Peters, R., Ruth van, S., Bouwmeester, H., 2008. A review of analytical methods for the identification and characterisation of nano delivery systems in food. Journal of Agricultural and Food Chemistry, ASAP Article, 10.1021/jf8013926.
  • 53
    • 31944448717 scopus 로고    scopus 로고
    • Development of a preliminary framework for informing the risk analysis and risk management of nanoparticles
    • Morgan K. Development of a preliminary framework for informing the risk analysis and risk management of nanoparticles. Risk Anal. 25 6 (2005) 1621-1635
    • (2005) Risk Anal. , vol.25 , Issue.6 , pp. 1621-1635
    • Morgan, K.1
  • 55
    • 31944451232 scopus 로고    scopus 로고
    • Toxic potential of materials at the nanolevel
    • Nel A., Xia T., Madler L., and Li N. Toxic potential of materials at the nanolevel. Science 311 5761 (2006) 622-627
    • (2006) Science , vol.311 , Issue.5761 , pp. 622-627
    • Nel, A.1    Xia, T.2    Madler, L.3    Li, N.4
  • 57
    • 33845214358 scopus 로고    scopus 로고
    • Oberdorster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W., Lai, D., 2005a. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Particle and Fibre Toxicology 2, 8
    • Oberdorster, G., Maynard, A., Donaldson, K., Castranova, V., Fitzpatrick, J., Ausman, K., Carter, J., Karn, B., Kreyling, W., Lai, D., 2005a. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Particle and Fibre Toxicology 2, 8
  • 58
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdorster G., Oberdorster E., and Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113 7 (2005) 823-839
    • (2005) Environ Health Perspect , vol.113 , Issue.7 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 60
    • 34147106483 scopus 로고    scopus 로고
    • Toxicology of nanoparticles: a historical perspective
    • Oberdorster G., Stone V., and Donaldson K. Toxicology of nanoparticles: a historical perspective. Nanotoxicology 1 1 (2007) 2-25
    • (2007) Nanotoxicology , vol.1 , Issue.1 , pp. 2-25
    • Oberdorster, G.1    Stone, V.2    Donaldson, K.3
  • 62
    • 0033992169 scopus 로고    scopus 로고
    • In vitro assessment of archaeosome stability for developing oral delivery systems
    • Patel G. In vitro assessment of archaeosome stability for developing oral delivery systems. International Journal of Pharmaceutics 194 1 (2000) 39-49
    • (2000) International Journal of Pharmaceutics , vol.194 , Issue.1 , pp. 39-49
    • Patel, G.1
  • 63
    • 33645133250 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation
    • Powers K.W., Brown S.C., Krishna V.B., Wasdo S.C., Moudgil B.M., and Roberts S.M. Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation. Toxicol. Sci. 90 2 (2006) 296-303
    • (2006) Toxicol. Sci. , vol.90 , Issue.2 , pp. 296-303
    • Powers, K.W.1    Brown, S.C.2    Krishna, V.B.3    Wasdo, S.C.4    Moudgil, B.M.5    Roberts, S.M.6
  • 64
    • 34147191540 scopus 로고    scopus 로고
    • Characterization of the size, shape and state of dispersion of nanoparticles for toxicological studies
    • Powers K.W., Moudgil B.M., and Roberts S.M. Characterization of the size, shape and state of dispersion of nanoparticles for toxicological studies. Nanotoxicology 1 1 (2007) 42-51
    • (2007) Nanotoxicology , vol.1 , Issue.1 , pp. 42-51
    • Powers, K.W.1    Moudgil, B.M.2    Roberts, S.M.3
  • 65
    • 38349052452 scopus 로고    scopus 로고
    • Nanotechnology in medical applications: State-of-the-art in materials and devices
    • 265001001/2005
    • Roszek B., de Jong W., and Geertsma R. Nanotechnology in medical applications: State-of-the-art in materials and devices. RIVM report (2005) 265001001/2005
    • (2005) RIVM report
    • Roszek, B.1    de Jong, W.2    Geertsma, R.3
  • 66
    • 33746191803 scopus 로고    scopus 로고
    • Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques
    • Rothen-Rutishauser B.M., Schurch S., Haenni B., Kapp N., and Gehr P. Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques. Environ. Sci. Technol. 40 14 (2006) 4353-4359
    • (2006) Environ. Sci. Technol. , vol.40 , Issue.14 , pp. 4353-4359
    • Rothen-Rutishauser, B.M.1    Schurch, S.2    Haenni, B.3    Kapp, N.4    Gehr, P.5
  • 67
    • 0032711921 scopus 로고    scopus 로고
    • Lectin-mediated transport of nanoparticles across Caco-2 and OK cells
    • Russell-Jones G.J., Veitch H., and Arthur L. Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. Int. J. Pharm. 190 2 (1999) 165-174
    • (1999) Int. J. Pharm. , vol.190 , Issue.2 , pp. 165-174
    • Russell-Jones, G.J.1    Veitch, H.2    Arthur, L.3
  • 68
    • 16244418685 scopus 로고    scopus 로고
    • Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium
    • Salamat-Miller N., and Johnston T.P. Current strategies used to enhance the paracellular transport of therapeutic polypeptides across the intestinal epithelium. International Journal of Pharmaceutics 294 1-2 (2005) 201-216
    • (2005) International Journal of Pharmaceutics , vol.294 , Issue.1-2 , pp. 201-216
    • Salamat-Miller, N.1    Johnston, T.P.2
  • 69
    • 59049092146 scopus 로고    scopus 로고
    • SCENIHR, 2007a. Scientific Committee on Emerging and Newly Identified Health Risk SCENIHR. Opinion on: the appropriateness of the risk assessment methodology in accordance with the technical guidance documents for new and existing substances for assessing the risks of nanomaterials European Commission Health and Consumer Protection Directorate-General. Directorate C-Public Health and Risk Assesment C7-Risk Assessment.
    • SCENIHR, 2007a. Scientific Committee on Emerging and Newly Identified Health Risk SCENIHR. Opinion on: the appropriateness of the risk assessment methodology in accordance with the technical guidance documents for new and existing substances for assessing the risks of nanomaterials European Commission Health and Consumer Protection Directorate-General. Directorate C-Public Health and Risk Assesment C7-Risk Assessment.
  • 70
    • 59049083368 scopus 로고    scopus 로고
    • SCENIHR, 2007b. Scientific Committee on Emerging and Newly Identified Health Risk SCENIHR. Opinion on : the scientific aspects of the existing and proposed definitions relating to products of nanoscience and nanotechnologies European Commission Health and Consumer Protection Directorate-General. Directorate C-Public Health and Risk Assessment C7-Risk Assessment.
    • SCENIHR, 2007b. Scientific Committee on Emerging and Newly Identified Health Risk SCENIHR. Opinion on : the scientific aspects of the existing and proposed definitions relating to products of nanoscience and nanotechnologies European Commission Health and Consumer Protection Directorate-General. Directorate C-Public Health and Risk Assessment C7-Risk Assessment.
  • 71
    • 33846326883 scopus 로고    scopus 로고
    • Nanotechnology approaches for drug and small molecule delivery across the blood-brain barrier
    • Silva G.A. Nanotechnology approaches for drug and small molecule delivery across the blood-brain barrier. Surgical Neurology 67 2 (2007) 113-116
    • (2007) Surgical Neurology , vol.67 , Issue.2 , pp. 113-116
    • Silva, G.A.1
  • 73
    • 0030948511 scopus 로고    scopus 로고
    • Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon
    • Szentkuti L. Light microscopical observations on luminally administered dyes, dextrans, nanospheres and microspheres in the pre-epithelial mucus gel layer of the rat distal colon. Journal of Controlled Release 46 3 (1997) 233-242
    • (1997) Journal of Controlled Release , vol.46 , Issue.3 , pp. 233-242
    • Szentkuti, L.1
  • 75
    • 59049107474 scopus 로고    scopus 로고
    • The Royal Society and the Royal Academy of Engineering, 2004. The Royal Society and the Royal Academy of Engineering. Nanoscience and nanotechnologies: opportunities and uncertainties. London, UK.
    • The Royal Society and the Royal Academy of Engineering, 2004. The Royal Society and the Royal Academy of Engineering. Nanoscience and nanotechnologies: opportunities and uncertainties. London, UK.
  • 76
    • 24944452398 scopus 로고    scopus 로고
    • Research strategies for safety evaluation of nanomaterials, part I: evaluating the human health implications of exposure to nanoscale materials
    • Thomas K., and Sayre P. Research strategies for safety evaluation of nanomaterials, part I: evaluating the human health implications of exposure to nanoscale materials. Toxicol. Sci. 87 2 (2005) 316-321
    • (2005) Toxicol. Sci. , vol.87 , Issue.2 , pp. 316-321
    • Thomas, K.1    Sayre, P.2
  • 77
    • 46349107675 scopus 로고    scopus 로고
    • Detection and characterization of engineered nanoparticles in food and the environment
    • Tiede K., Boxall A.B., Tear S.P., Lewis J., David H., and Hassellov M. Detection and characterization of engineered nanoparticles in food and the environment. Food Addit. Contam. 25 7 (2008) 795-821
    • (2008) Food Addit. Contam. , vol.25 , Issue.7 , pp. 795-821
    • Tiede, K.1    Boxall, A.B.2    Tear, S.P.3    Lewis, J.4    David, H.5    Hassellov, M.6
  • 78
    • 59049107025 scopus 로고    scopus 로고
    • Tran, C.L., Danaldson, K., Stones, V., Fernandez, T., Ford, A., Christofi, N., Ayres, J.G., Steiner, M., Hurley, J.F., Aitken, R.J. et al., 2005. A scoping study to identify hazard data needs for addressing risks presented by nanoparticles and nanotubes. Institute of Occupational Medicine (IOM) Research Report, Edinburgh, United Kingdom.
    • Tran, C.L., Danaldson, K., Stones, V., Fernandez, T., Ford, A., Christofi, N., Ayres, J.G., Steiner, M., Hurley, J.F., Aitken, R.J. et al., 2005. A scoping study to identify hazard data needs for addressing risks presented by nanoparticles and nanotubes. Institute of Occupational Medicine (IOM) Research Report, Edinburgh, United Kingdom.
  • 81
    • 33846131928 scopus 로고    scopus 로고
    • Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration
    • Wang J., Zhou G., Chen C., Yu H., Wang T., Ma Y., Jia G., Gao Y., Li B., and Sun J. Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicol. Lett. 168 2 (2007) 176-185
    • (2007) Toxicol. Lett. , vol.168 , Issue.2 , pp. 176-185
    • Wang, J.1    Zhou, G.2    Chen, C.3    Yu, H.4    Wang, T.5    Ma, Y.6    Jia, G.7    Gao, Y.8    Li, B.9    Sun, J.10
  • 83
    • 0346336105 scopus 로고    scopus 로고
    • Size, stability, and entrapment efficiency of phospholipid nanocapsules containing polypeptide antimicrobials
    • Were L.M., Bruce B.D., Davidson P.M., and Weiss J. Size, stability, and entrapment efficiency of phospholipid nanocapsules containing polypeptide antimicrobials. Journal of Agricultural and Food Chemistry 51 27 (2003) 8073-8079
    • (2003) Journal of Agricultural and Food Chemistry , vol.51 , Issue.27 , pp. 8073-8079
    • Were, L.M.1    Bruce, B.D.2    Davidson, P.M.3    Weiss, J.4
  • 84
    • 59049090696 scopus 로고    scopus 로고
    • Woodrow Wilson International Center for Scholars. Assuring the safety of nanomaterials in food packaging: the regulatory process and key issues. Available from: (accessed 28.08.2008).
    • Woodrow Wilson International Center for Scholars. Assuring the safety of nanomaterials in food packaging: the regulatory process and key issues. Available from: (accessed 28.08.2008).
  • 85
    • 33749603224 scopus 로고    scopus 로고
    • Nanocochleate cylinders for oral & parenteral delivery of drugs
    • Zarif L. Nanocochleate cylinders for oral & parenteral delivery of drugs. Journal of liposome research 13 1 (2003) 109-110
    • (2003) Journal of liposome research , vol.13 , Issue.1 , pp. 109-110
    • Zarif, L.1
  • 86
    • 11144331077 scopus 로고    scopus 로고
    • Comparison of short-term toxicity between Nano-Se and selenite in mice
    • Zhang J., Wang H., Yan X., and Zhang L. Comparison of short-term toxicity between Nano-Se and selenite in mice. Life Sci. 76 10 (2005) 1099-1109
    • (2005) Life Sci. , vol.76 , Issue.10 , pp. 1099-1109
    • Zhang, J.1    Wang, H.2    Yan, X.3    Zhang, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.