Cytotoxic effects of hydroxylated fullerenes on isolated rat hepatocytes via mitochondrial dysfunction

Archives of Toxicology

Volumn 85, Issue 11, 2011, Pages 1429-1440

  Nakagawa, Yoshio ^a   Suzuki, Toshinari ^a   Ishii, Hidemi ^b   Nakae, Dai ^a   Ogata, Akio ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cytotoxicity; Fullerenols; Hydroxylated fullerene; Mitochondrial dysfunction; Oxidative stress; Rat hepatocytes

Indexed keywords

ADENOSINE TRIPHOSPHATE; FULLERENE; FULLERENE DERIVATIVE; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALONALDEHYDE; OXYGEN RADICAL;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; LIPID PEROXIDATION; LIVER CELL; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

ANIMALS; CELL DEATH; CELL RESPIRATION; CELLS, CULTURED; CYTOTOXINS; FULLERENES; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEPATOCYTES; HYDROXYLATION; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; RATS; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; SULFHYDRYL COMPOUNDS;

RATTUS;

EID: 80755163163     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0688-z     Document Type: Article

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