Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 46, 2013, Pages 18490-18495

  Scholz, Carsten C ^a   Cavadas, Miguel A S ^a   Tambuwala, Murtaza M ^a,b   Hams, Emily ^b   Rodríguez, Javier ^a   Von Kriegsheim, Alex ^a   Cotter, Philip ^a   Bruning, Ulrike ^a   Fallon, Padraic G ^b   Cheong, Alex ^a   Cummins, Eoin P ^a   Taylor, Cormac T ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Inflammatory disease; OTUB1; Oxygen; UBC13

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; OXYGENASE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

INFLAMMATORY DISEASE; OTUB1; OXYGEN; UBC13;

ANALYSIS OF VARIANCE; ANOXIA; BLOTTING, WESTERN; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; HYDROXYLATION; IMMUNOPRECIPITATION; INFLAMMATION; INTERLEUKIN-1BETA; LUCIFERASES; MASS SPECTROMETRY; MIXED FUNCTION OXYGENASES; NF-KAPPA B; PROLYL HYDROXYLASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS;

EID: 84887501809     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1309718110     Document Type: Article

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