Arsenite induces apoptosis in human mesenchymal stem cells by altering Bcl-2 family proteins and by activating intrinsic pathway

Toxicology and Applied Pharmacology

Volumn 244, Issue 3, 2010, Pages 263-272

  Yadav, Santosh ^a   Shi, Yongli ^a   Wang, Feng ^a   Wang, He ^a  

^a TULANE UNIVERSITY   (United States)

Author keywords

Annexin V staining; G2 M arrest; Human mesenchymal stem cells; S phase; TUNEL

Indexed keywords

ARSENIC TRIOXIDE; DNA; MESSENGER RNA; PHOSPHATIDYLSERINE; PROTEIN BCL 2; ARSENOUS ACID DERIVATIVE; CASPASE 3; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEIC ACID SYNTHESIS INHIBITOR; PROTEIN BAX;

ADULT; APOPTOSIS; ARSENIC POISONING; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL GROWTH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; GENE EXPRESSION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; PROTEIN EXPRESSION; CELL CYCLE; CELL PROLIFERATION; DRUG EFFECT; GENETICS; METABOLISM; POLLUTANT; UPREGULATION;

APOPTOSIS; ARSENITES; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; ENVIRONMENTAL POLLUTANTS; GENE EXPRESSION; HUMANS; MESENCHYMAL STEM CELLS; METABOLIC NETWORKS AND PATHWAYS; NUCLEIC ACID SYNTHESIS INHIBITORS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; UP-REGULATION;

EID: 77950496474     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2010.01.001     Document Type: Article

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