Morphological and functional alterations in human proximal tubular cell line induced by low level inorganic arsenic: Evidence for targeting of mitochondria and initiated apoptosis

Journal of Applied Toxicology

Volumn 26, Issue 4, 2006, Pages 356-367

  Peraza, Marjorie A ^a,d   Cromey, Douglas W ^b   Carolus, Barb ^c   Carter, Dean E ^a   Gandolfi, A Jay ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Arsenic; Cell death; Human kidney cell line; Mitochondria

Indexed keywords

ARSENIC; ARSENIC TRIOXIDE; PHOSPHATIDYLSERINE;

APOPTOSIS; ARTICLE; CELL FUNCTION; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CELL RESPIRATION; CYTOPLASM; CYTOTOXICITY; HUMAN; HUMAN CELL; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MITOCHONDRION; MORPHOLOGICAL TRAIT; NECROSIS; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY;

APOPTOSIS; ARSENATES; ARSENITES; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FLUORESCENT DYES; HUMANS; KIDNEY TUBULES, PROXIMAL; MEMBRANE POTENTIALS; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; ORGANIC CHEMICALS; SODIUM COMPOUNDS; TIME FACTORS;

EID: 33746019572     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1149     Document Type: Article

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