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Volumn 4, Issue 10, 2013, Pages

Excitotoxic cell death induces delayed proliferation of endogenous neuroprogenitor cells in organotypic slice cultures of the rat spinal cord

Author keywords

Glial precursor; Kainic acid; Neuronal precursor; Spinal cord injury; Stem cells

Indexed keywords

GLUTAMIC ACID; KAINIC ACID;

EID: 84887463913     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.431     Document Type: Article
Times cited : (27)

References (57)
  • 1
    • 34547730638 scopus 로고    scopus 로고
    • Curiosity and cure: Translational research strategies for neural repair-mediated rehabilitation
    • Dobkin BH. Curiosity and cure: Translational research strategies for neural repair-mediated rehabilitation. Dev Neurobiol 2007; 67: 1133-1147
    • (2007) Dev Neurobiol , vol.67 , pp. 1133-1147
    • Dobkin, B.H.1
  • 4
    • 84859905286 scopus 로고    scopus 로고
    • Cell-based transplantation strategies to promote plasticity following spinal cord injury
    • Ruff CA, Wilcox JT, Fehlings MG. Cell-based transplantation strategies to promote plasticity following spinal cord injury. Exp Neurol 2012; 235: 78-90
    • (2012) Exp Neurol , vol.235 , pp. 78-90
    • Ruff, C.A.1    Wilcox, J.T.2    Fehlings, M.G.3
  • 5
    • 77954862426 scopus 로고    scopus 로고
    • Stem cell therapies for spinal cord injury
    • Sahni V, Kessler JA. Stem cell therapies for spinal cord injury. Nat Rev Neurol 2010; 6: 363-372
    • (2010) Nat Rev Neurol , vol.6 , pp. 363-372
    • Sahni, V.1    Kessler, J.A.2
  • 6
    • 0032967382 scopus 로고    scopus 로고
    • The role of excitotoxicity in neurodegenerative disease: Implications for therapy
    • Doble A. The role of excitotoxicity in neurodegenerative disease: Implications for therapy. Pharmacol Ther 1999; 81: 163-221
    • (1999) Pharmacol Ther , vol.81 , pp. 163-221
    • Doble, A.1
  • 7
    • 0036454326 scopus 로고    scopus 로고
    • Secondary injury mechanisms of spinal cord trauma: A novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole
    • Schwartz G, Fehlings MG. Secondary injury mechanisms of spinal cord trauma: A novel therapeutic approach for the management of secondary pathophysiology with the sodium channel blocker riluzole. Prog Brain Res 2002; 137: 177-190
    • (2002) Prog Brain Res , vol.137 , pp. 177-190
    • Schwartz, G.1    Fehlings, M.G.2
  • 8
    • 84861164255 scopus 로고    scopus 로고
    • Understanding secondary injury
    • Borgens RB, Liu-Snyder P. Understanding secondary injury. Q Rev Biol 2012; 87: 89-127
    • (2012) Q Rev Biol , vol.87 , pp. 89-127
    • Borgens, R.B.1    Liu-Snyder, P.2
  • 9
    • 0028812680 scopus 로고
    • Update on the pathophysiology and pathology of acute spinal cord injury
    • Tator CH. Update on the pathophysiology and pathology of acute spinal cord injury. Brain Pathol 1995; 5: 407-413
    • (1995) Brain Pathol , vol.5 , pp. 407-413
    • Tator, C.H.1
  • 10
    • 79955021464 scopus 로고    scopus 로고
    • The spinal cord ependymal region: A stem cell niche in the caudal central nervous system
    • Hugnot JP, Franzen R. The spinal cord ependymal region: A stem cell niche in the caudal central nervous system. Front Biosci 2011; 16: 1044-1059
    • (2011) Front Biosci , vol.16 , pp. 1044-1059
    • Hugnot, J.P.1    Franzen, R.2
  • 11
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell 2008; 132: 645-660
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3
  • 12
    • 0035894866 scopus 로고    scopus 로고
    • Transcription factor Expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord
    • Yamamoto S, Nagao M, Sugimori M, Kosako H, Nakatomi H, Yamamoto N et al. Transcription factor Expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord. J Neurosci 2001; 21: 9814-9823
    • (2001) J Neurosci , vol.21 , pp. 9814-9823
    • Yamamoto, S.1    Nagao, M.2    Sugimori, M.3    Kosako, H.4    Nakatomi, H.5    Yamamoto, N.6
  • 14
    • 0035214298 scopus 로고    scopus 로고
    • Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord
    • Yamamoto S, Yamamoto N, Kitamura T, Nakamura K, Nakafuku M. Proliferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol 2001; 172: 115-127
    • (2001) Exp Neurol , vol.172 , pp. 115-127
    • Yamamoto, S.1    Yamamoto, N.2    Kitamura, T.3    Nakamura, K.4    Nakafuku, M.5
  • 15
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
    • Johe KK, Hazel TG, Muller T, Dugich-Djordjevic MM, McKay RD. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev 1996; 10: 3129-3140
    • (1996) Genes Dev , vol.10 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugich-Djordjevic, M.M.4    McKay, R.D.5
  • 16
    • 80051579878 scopus 로고    scopus 로고
    • Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures
    • Mazzone GL, Nistri A. Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures. Neuroscience 2011; 190: 318-327
    • (2011) Neuroscience , vol.190 , pp. 318-327
    • Mazzone, G.L.1    Nistri, A.2
  • 17
    • 79955554974 scopus 로고    scopus 로고
    • Effect of the PARP-1 Inhibitor PJ 34 on excitotoxic damage evoked by kainate on rat spinal cord organotypic slices
    • Mazzone GL, Nistri A. Effect of the PARP-1 Inhibitor PJ 34 on excitotoxic damage evoked by kainate on rat spinal cord organotypic slices. Cell Mol Neurobiol 2011; 31: 469-478
    • (2011) Cell Mol Neurobiol , vol.31 , pp. 469-478
    • Mazzone, G.L.1    Nistri, A.2
  • 18
    • 33744901157 scopus 로고    scopus 로고
    • Locomotor circuits in the mammalian spinal cord
    • Kiehn O. Locomotor circuits in the mammalian spinal cord. Annu Rev Neurosci 2006; 29: 279-306
    • (2006) Annu Rev Neurosci , vol.29 , pp. 279-306
    • Kiehn, O.1
  • 19
    • 79953043583 scopus 로고    scopus 로고
    • Electrochemical detection of endogenous glutamate release from rat spinal cord organotypic slices as a real-time method to monitor excitotoxicity
    • Mazzone GL, Nistri A. Electrochemical detection of endogenous glutamate release from rat spinal cord organotypic slices as a real-time method to monitor excitotoxicity. J Neurosci Methods 2011; 197: 128-132
    • (2011) J Neurosci Methods , vol.197 , pp. 128-132
    • Mazzone, G.L.1    Nistri, A.2
  • 20
    • 84861235455 scopus 로고    scopus 로고
    • Pathway-specific plasticity in the human spinal cord
    • Leukel C, Taube W, Beck S, Schubert M. Pathway-specific plasticity in the human spinal cord. Eur J Neurosci 2012; 35: 1622-1629
    • (2012) Eur J Neurosci , vol.35 , pp. 1622-1629
    • Leukel, C.1    Taube, W.2    Beck, S.3    Schubert, M.4
  • 21
    • 33645107862 scopus 로고    scopus 로고
    • Neurogenesis in the adult hippocampus
    • Christie BR, Cameron HA. Neurogenesis in the adult hippocampus. Hippocampus 2006; 16: 199-207
    • (2006) Hippocampus , vol.16 , pp. 199-207
    • Christie, B.R.1    Cameron, H.A.2
  • 22
    • 84863565187 scopus 로고    scopus 로고
    • Postnatal developmental profile of neurons and glia in motor nuclei of the brainstem and spinal cord, and its comparison with organotypic slice cultures
    • Cifra A, Mazzone GL, Nani F, Nistri A, Mladinic M. Postnatal developmental profile of neurons and glia in motor nuclei of the brainstem and spinal cord, and its comparison with organotypic slice cultures. Dev Neurobiol 2012; 72: 1140-1160
    • (2012) Dev Neurobiol , vol.72 , pp. 1140-1160
    • Cifra, A.1    Mazzone, G.L.2    Nani, F.3    Nistri, A.4    Mladinic, M.5
  • 23
    • 0024465254 scopus 로고
    • Development of glial cells in the cerebral wall of ferrets: Direct tracing of their transformation from radial glia into astrocytes
    • Voigt T. Development of glial cells in the cerebral wall of ferrets: Direct tracing of their transformation from radial glia into astrocytes. J Comp Neurol 1989; 289: 74-88
    • (1989) J Comp Neurol , vol.289 , pp. 74-88
    • Voigt, T.1
  • 24
    • 84876012910 scopus 로고    scopus 로고
    • Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats
    • Liu C, Wu W, Zhang B, Xiang J, Zou J. Temporospatial expression and cellular localization of glutamine synthetase following traumatic spinal cord injury in adult rats. Mol Med Rep 2013; 7: 1431-1436
    • (2013) Mol Med Rep , vol.7 , pp. 1431-1436
    • Liu, C.1    Wu, W.2    Zhang, B.3    Xiang, J.4    Zou, J.5
  • 25
    • 84890556640 scopus 로고    scopus 로고
    • Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression
    • e-pub ahead of print 30 August 2013
    • Yeh C-Y, Verkhratsky A, Terzieva S, Rodríguez JJ. Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression. Biogerontology 2013; e-pub ahead of print 30 August 2013
    • (2013) Biogerontology
    • Yeh, C.-Y.1    Verkhratsky, A.2    Terzieva, S.3    Rodríguez, J.J.4
  • 26
    • 84877074745 scopus 로고    scopus 로고
    • Development of the microglial phenotype in culture
    • Szabo M, Gulya K. Development of the microglial phenotype in culture. Neuroscience 2013; 241: 280-295
    • (2013) Neuroscience , vol.241 , pp. 280-295
    • Szabo, M.1    Gulya, K.2
  • 27
    • 84872149088 scopus 로고    scopus 로고
    • A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion
    • Morrison HW, Filosa JA. A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion. J Neuroinflammation 2013; 10: 4
    • (2013) J Neuroinflammation , vol.10 , pp. 4
    • Morrison, H.W.1    Filosa, J.A.2
  • 28
    • 33847026077 scopus 로고    scopus 로고
    • Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability
    • Vreugdenhil E, Kolk SM, Boekhoorn K, Fitzsimons CP, Schaaf M, Schouten T et al. Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability. Eur J Neurosci 2007; 25: 635-648
    • (2007) Eur J Neurosci , vol.25 , pp. 635-648
    • Vreugdenhil, E.1    Kolk, S.M.2    Boekhoorn, K.3    Fitzsimons, C.P.4    Schaaf, M.5    Schouten, T.6
  • 30
    • 49349106393 scopus 로고    scopus 로고
    • Kainate and metabolic perturbation mimicking spinal injury differentially contribute to early damage of locomotor networks in the in vitro neonatal rat spinal cord
    • Taccola G, Margaryan G, Mladinic M, Nistri A. Kainate and metabolic perturbation mimicking spinal injury differentially contribute to early damage of locomotor networks in the in vitro neonatal rat spinal cord. Neuroscience 2008; 155: 538-555
    • (2008) Neuroscience , vol.155 , pp. 538-555
    • Taccola, G.1    Margaryan, G.2    Mladinic, M.3    Nistri, A.4
  • 31
    • 0035074297 scopus 로고    scopus 로고
    • Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion
    • Grossman SD, Rosenberg LJ, Wrathall Jr. Temporal-spatial pattern of acute neuronal and glial loss after spinal cord contusion. Exp Neurol 2001; 168: 273-282
    • (2001) Exp Neurol , vol.168 , pp. 273-282
    • Grossman, S.D.1    Rosenberg, L.J.2    Wrathall, J.R.3
  • 32
    • 83055163963 scopus 로고    scopus 로고
    • Molecular mechanisms underlying cell death in spinal networks in relation to locomotor activity after acute injury in vitro
    • Kuzhandaivel A, Nistri A, Mazzone GL, Mladinic M. Molecular mechanisms underlying cell death in spinal networks in relation to locomotor activity after acute injury in vitro. Front Cell Neurosci 2011; 5: 9
    • (2011) Front Cell Neurosci , vol.5 , pp. 9
    • Kuzhandaivel, A.1    Nistri, A.2    Mazzone, G.L.3    Mladinic, M.4
  • 33
    • 77249125330 scopus 로고    scopus 로고
    • Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment
    • Beck KD, Nguyen HX, Galvan MD, Salazar DL, Woodruff TM, Anderson AJ. Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain 2010; 133: 433-447
    • (2010) Brain , vol.133 , pp. 433-447
    • Beck, K.D.1    Nguyen, H.X.2    Galvan, M.D.3    Salazar, D.L.4    Woodruff, T.M.5    Anderson, A.J.6
  • 35
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005; 308: 1314-1348
    • (2005) Science , vol.308 , pp. 1314-1348
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 36
    • 0028652288 scopus 로고
    • Which proliferation markers for routine immunohistology? A comparison of five antibodies
    • Rose DS, Maddox PH, Brown DC. Which proliferation markers for routine immunohistology? A comparison of five antibodies. J Clin Pathol 1994; 47: 1010-1014
    • (1994) J Clin Pathol , vol.47 , pp. 1010-1014
    • Rose, D.S.1    Maddox, P.H.2    Brown, D.C.3
  • 37
    • 0037039823 scopus 로고    scopus 로고
    • Repairing the injured spinal cord
    • Schwab ME. Repairing the injured spinal cord. Science 2002; 295: 1029-1031
    • (2002) Science , vol.295 , pp. 1029-1031
    • Schwab, M.E.1
  • 38
    • 84857194696 scopus 로고    scopus 로고
    • The S100B protein in biological fluids: More than a lifelong biomarker of brain distress
    • Michetti F, Corvino V, Geloso MC, Lattanzi W, Bernardini C, Serpero L et al. The S100B protein in biological fluids: More than a lifelong biomarker of brain distress. J Neurochem 2012; 120: 644-659
    • (2012) J Neurochem , vol.120 , pp. 644-659
    • Michetti, F.1    Corvino, V.2    Geloso, M.C.3    Lattanzi, W.4    Bernardini, C.5    Serpero, L.6
  • 39
    • 84858619494 scopus 로고    scopus 로고
    • Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid
    • Pérez-Gómez A, Tasker RA. Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid. Neuroscience 2012; 208: 97-108
    • (2012) Neuroscience , vol.208 , pp. 97-108
    • Pérez-Gómez, A.1    Tasker, R.A.2
  • 40
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D, Kokaia Z, Lindvall O. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002; 8: 963-970
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3    Kokaia, Z.4    Lindvall, O.5
  • 41
    • 33644774441 scopus 로고    scopus 로고
    • Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation
    • Bonde S, Ekdahl CT, Lindvall O. Long-term neuronal replacement in adult rat hippocampus after status epilepticus despite chronic inflammation. Eur J Neurosci 2006; 23: 965-974
    • (2006) Eur J Neurosci , vol.23 , pp. 965-974
    • Bonde, S.1    Ekdahl, C.T.2    Lindvall, O.3
  • 42
    • 58149474392 scopus 로고    scopus 로고
    • Kainate receptors in epilepsy and excitotoxicity
    • Vincent P, Mulle C. Kainate receptors in epilepsy and excitotoxicity. Neuroscience 2009; 158: 309-323
    • (2009) Neuroscience , vol.158 , pp. 309-323
    • Vincent, P.1    Mulle, C.2
  • 43
    • 70349754683 scopus 로고    scopus 로고
    • Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury
    • Gwak YS, Unabia GC, Hulsebosch CE. Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. Exp Neurol 2009; 220: 154-161
    • (2009) Exp Neurol , vol.220 , pp. 154-161
    • Gwak, Y.S.1    Unabia, G.C.2    Hulsebosch, C.E.3
  • 44
    • 0033565016 scopus 로고    scopus 로고
    • Novel injury mechanism in anoxia and trauma of spinal cord white matter: Glutamate release via reverse Na+-dependent glutamate transport
    • Li S, Mealing GA, Morley P, Stys PK. Novel injury mechanism in anoxia and trauma of spinal cord white matter: glutamate release via reverse Na+-dependent glutamate transport. J Neurosci 1999; 19: RC16
    • (1999) J Neurosci , vol.19
    • Li, S.1    Mealing, G.A.2    Morley, P.3    Stys, P.K.4
  • 45
    • 0034717084 scopus 로고    scopus 로고
    • Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord
    • McAdoo DJ, Xu G, Robak G, Hughes MG, Price EM. Evidence that reversed glutamate uptake contributes significantly to glutamate release following experimental injury to the rat spinal cord. Brain Res 2000; 865: 283-285
    • (2000) Brain Res , vol.865 , pp. 283-285
    • McAdoo, D.J.1    Xu, G.2    Robak, G.3    Hughes, M.G.4    Price, E.M.5
  • 46
    • 77956177653 scopus 로고    scopus 로고
    • Persistent inward currents in spinal motoneurons: Important for normal function but potentially harmful after spinal cord injury and in amyotrophic lateral sclerosis
    • ElBasiouny SM, Schuster JE, Heckman CJ. Persistent inward currents in spinal motoneurons: Important for normal function but potentially harmful after spinal cord injury and in amyotrophic lateral sclerosis. Clin Neurophysiol 2010; 121: 1669-1679
    • (2010) Clin Neurophysiol , vol.121 , pp. 1669-1679
    • ElBasiouny, S.M.1    Schuster, J.E.2    Heckman, C.J.3
  • 47
    • 14844336917 scopus 로고    scopus 로고
    • The effect of glutamate receptor blockers on glutamate release following spinal cord injury Lack of evidence for an ongoing feedback cascade of damage -4glutamate release -4damage -4glutamate release -4 etc
    • McAdoo DJ, Hughes MG, Nie L, Shah B, Clifton C, Fullwood S et al. The effect of glutamate receptor blockers on glutamate release following spinal cord injury. Lack of evidence for an ongoing feedback cascade of damage -4glutamate release -4damage -4glutamate release -4 etc. Brain Res 2005; 1038: 92-99
    • (2005) Brain Res , vol.1038 , pp. 92-99
    • McAdoo, D.J.1    Hughes, M.G.2    Nie, L.3    Shah, B.4    Clifton, C.5    Fullwood, S.6
  • 50
    • 84872823325 scopus 로고    scopus 로고
    • Stem cell based strategies for spinal cord injury repair
    • Reeves A, Keirstead HS. Stem cell based strategies for spinal cord injury repair. Adv Exp Med Biol 2012; 760: 16-24
    • (2012) Adv Exp Med Biol , vol.760 , pp. 16-24
    • Reeves, A.1    Keirstead, H.S.2
  • 51
  • 52
    • 84870249383 scopus 로고    scopus 로고
    • Management strategies for acute spinal cord injury: Current options and future perspectives
    • Stahel PF, VanderHeiden T, Finn MA. Management strategies for acute spinal cord injury: Current options and future perspectives. Curr Opin Crit Care 2012; 18: 651-660
    • (2012) Curr Opin Crit Care , vol.18 , pp. 651-660
    • Stahel, P.F.1    VanderHeiden, T.2    Finn, M.A.3
  • 53
    • 77952875450 scopus 로고    scopus 로고
    • Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord
    • Mazzone GL, Margaryan G, Kuzhandaivel A, Nasrabady SE, Mladinic M, Nistri A. Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord. Neuroscience 2010; 168: 451-462
    • (2010) Neuroscience , vol.168 , pp. 451-462
    • Mazzone, G.L.1    Margaryan, G.2    Kuzhandaivel, A.3    Nasrabady, S.E.4    Mladinic, M.5    Nistri, A.6
  • 54
    • 0025935416 scopus 로고
    • An organotypic spinal cord - dorsal root ganglion - skeletal muscle coculture of embryonic rat i the morphological correlates of the spinal reflex arc
    • Spenger C, Braschler UF, Streit J, Luscher HR. An organotypic spinal cord - dorsal root ganglion - skeletal muscle coculture of embryonic rat. I. The morphological correlates of the spinal reflex Arc. Eur J Neurosci 1991; 3: 1037-1053
    • (1991) Eur J Neurosci , vol.3 , pp. 1037-1053
    • Spenger, C.1    Braschler, U.F.2    Streit, J.3    Luscher, H.R.4
  • 55
    • 0026038918 scopus 로고
    • An organotypic spinal cord - dorsal root ganglion - skeletal muscle coculture of embryonic rat. II. Functional evidence for the formation of spinal reflex arcs in vitro
    • Streit J, Spenger C, Luscher HR. An organotypic spinal cord - dorsal root ganglion - skeletal muscle coculture of embryonic rat. II. functional evidence for the formation of spinal reflex arcs in vitro. Eur J Neurosci 1991; 3: 1054-1068
    • (1991) Eur J Neurosci , vol.3 , pp. 1054-1068
    • Streit, J.1    Spenger, C.2    Luscher, H.R.3
  • 56
    • 33745002751 scopus 로고    scopus 로고
    • Examination of granule layer cell count, cell density, and single-pulse BrdU incorporation in rat organotypic hippocampal slice cultures with respect to culture medium, septotemporal position, and time in vitro
    • Sadgrove MP, Laskowski A, Gray WP. Examination of granule layer cell count, cell density, and single-pulse BrdU incorporation in rat organotypic hippocampal slice cultures with respect to culture medium, septotemporal position, and time in vitro. J Comp Neurol 2006; 497: 397-415
    • (2006) J Comp Neurol , vol.497 , pp. 397-415
    • Sadgrove, M.P.1    Laskowski, A.2    Gray, W.P.3
  • 57
    • 0026465350 scopus 로고
    • Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons
    • Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT et al. Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev Dyn 1992; 194: 209-221
    • (1992) Dev Dyn , vol.194 , pp. 209-221
    • Cashman, N.R.1    Durham, H.D.2    Blusztajn, J.K.3    Oda, K.4    Tabira, T.5    Shaw, I.T.6


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