Oncogenes and angiogenesis: A way to personalize anti-angiogenic therapy?

Cellular and Molecular Life Sciences

Volumn 70, Issue 21, 2013, Pages 4131-4140

  Bottos, Alessia ^a   Bardelli, Alberto ^b,c,d  

^a FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^b UNIVERSITY OF TURIN   (Italy)

^c CANDIOLO CANCER INSTITUTE   (Italy)

^d FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

Author keywords

Angiogenesis; Anti angiogenic therapy; Oncogenes; Targeted therapy; Vessel normalization

Indexed keywords

1 (1 CYANO 1 METHYLETHYL) 3 METHYL 8 (3 QUINOLINYL)IMIDAZO[4,5 C]QUINOLIN 2(1H,3H) ONE; 2 (4 HYDROXYPHENYL) 4 MORPHOLINOPYRIDO[3',2':4,5]FURO[3,2 D]PYRIMIDINE; B RAF KINASE; BEVACIZUMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERLOTINIB; GEFITINIB; MAMMALIAN TARGET OF RAPAMYCIN; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; NELFINAVIR; PAZOPANIB; PHOSPHATIDYLINOSITOL 3 KINASE; SORAFENIB; SUNITINIB; TRASTUZUMAB; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VEMURAFENIB;

ANGIOGENESIS; ANTIANGIOGENIC ACTIVITY; ANTIANGIOGENIC THERAPY; CANCER SURVIVAL; DRUG RESPONSE; DRUG TARGETING; GENE MUTATION; HUMAN; HYPOXIA; KIDNEY CANCER; LIVER CELL CARCINOMA; METASTATIC COLORECTAL CANCER; MOLECULARLY TARGETED THERAPY; NONHUMAN; ONCOGENE; PERSONALIZED MEDICINE; PHASE 3 CLINICAL TRIAL (TOPIC); REVIEW; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDIVIDUALIZED MEDICINE; MUTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; ONCOGENES;

EID: 84887121023     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1331-3     Document Type: Review

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