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Volumn 93, Issue 21, 2013, Pages 763-772

Development and characterization of a novel controlled release drug delivery system based on nanostructured lipid carriers gel for meloxicam

Author keywords

Carrageenan induced paw edema model; Controlled release; Hemocompatibility; Meloxicam; Nanostructured lipid carriers; Permeation rate

Indexed keywords

ANTIINFLAMMATORY AGENT; DRUG CARRIER; MELOXICAM; NANOSTRUCTURED LIPID CARRIER; UNCLASSIFIED DRUG; DELAYED RELEASE FORMULATION; GEL; NANOMATERIAL; NONSTEROID ANTIINFLAMMATORY AGENT; THIAZINE DERIVATIVE; THIAZOLE DERIVATIVE;

EID: 84887110369     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.09.027     Document Type: Article
Times cited : (88)

References (52)
  • 1
    • 78049316339 scopus 로고    scopus 로고
    • Development, evaluation and clinical studies of Acitretin loaded nanostructured lipid carriers for topical treatment of psoriasis
    • Y. Agrawal, K.C. Petkar, and K.K. Sawant Development, evaluation and clinical studies of Acitretin loaded nanostructured lipid carriers for topical treatment of psoriasis Int J Pharm 401 2010 93 102
    • (2010) Int J Pharm , vol.401 , pp. 93-102
    • Agrawal, Y.1    Petkar, K.C.2    Sawant, K.K.3
  • 2
    • 8544253205 scopus 로고    scopus 로고
    • Transdermal self-permeation enhancement of ibuprofen
    • S.M. Al-Saidan Transdermal self-permeation enhancement of ibuprofen J Control Release 100 2004 199 209
    • (2004) J Control Release , vol.100 , pp. 199-209
    • Al-Saidan, S.M.1
  • 3
    • 33644990077 scopus 로고    scopus 로고
    • Thermotropic and spectroscopic behavior of skin: Relationship with percutaneous permeation enhancement
    • K. Babita, V. Kumar, V. Rana, S. Jain, and A.K. Tiwary Thermotropic and spectroscopic behavior of skin: relationship with percutaneous permeation enhancement Curr Drug Deliv 3 2006 95 113
    • (2006) Curr Drug Deliv , vol.3 , pp. 95-113
    • Babita, K.1    Kumar, V.2    Rana, V.3    Jain, S.4    Tiwary, A.K.5
  • 4
    • 0029891990 scopus 로고    scopus 로고
    • Phase behavior of lecithin-water mixtures in n-hexane and near-critical propane influence of cosurfactants caprylic acid and 1-butanol
    • K.A. Bartscherer, M. Minier, and H. Renon Phase behavior of lecithin-water mixtures in n-hexane and near-critical propane influence of cosurfactants caprylic acid and 1-butanol J Colloid Interface Sci 180 1996 77 85
    • (1996) J Colloid Interface Sci , vol.180 , pp. 77-85
    • Bartscherer, K.A.1    Minier, M.2    Renon, H.3
  • 5
    • 0024309114 scopus 로고
    • Use of an in vitro haemolysis test to predict tissue irritancy in an intramuscular formulation
    • S. Brown, L. Templeton, D.A. Prater, and C.J. Potter Use of an in vitro haemolysis test to predict tissue irritancy in an intramuscular formulation J Parenter Sci Technol 43 1989 117 120
    • (1989) J Parenter Sci Technol , vol.43 , pp. 117-120
    • Brown, S.1    Templeton, L.2    Prater, D.A.3    Potter, C.J.4
  • 6
    • 0031848454 scopus 로고    scopus 로고
    • Effect of vehicles on yohimbine permeation across excised hairless mouse skin
    • V. Carelli, G. Di Colo, E. Nannipieri, and M.F. Serafini Effect of vehicles on yohimbine permeation across excised hairless mouse skin Pharm Acta Helv 73 1998 127 134
    • (1998) Pharm Acta Helv , vol.73 , pp. 127-134
    • Carelli, V.1    Di Colo, G.2    Nannipieri, E.3    Serafini, M.F.4
  • 7
    • 33646937390 scopus 로고    scopus 로고
    • Effect of the composition of lecithin/n-propanol/isopropyl myristate/water microemulsions on barrier properties of rat skin for transdermal permeation of tetracaine hydrochloride: In vitro
    • M. Changez, M. Varshney, J. Chander, and A.K. Dinda Effect of the composition of lecithin/n-propanol/isopropyl myristate/water microemulsions on barrier properties of rat skin for transdermal permeation of tetracaine hydrochloride: in vitro Colloids Surf B Biointerfaces 50 2006 18 25
    • (2006) Colloids Surf B Biointerfaces , vol.50 , pp. 18-25
    • Changez, M.1    Varshney, M.2    Chander, J.3    Dinda, A.K.4
  • 8
    • 52449115600 scopus 로고    scopus 로고
    • Characterization of spreadability of nonaqueous ethylcellulose gel matrices using dynamic contact angle
    • K.T. Chow, L.W. Chan, and P.W.S. Heng Characterization of spreadability of nonaqueous ethylcellulose gel matrices using dynamic contact angle J Pharm Sci 97 2008 3467 3482
    • (2008) J Pharm Sci , vol.97 , pp. 3467-3482
    • Chow, K.T.1    Chan, L.W.2    Heng, P.W.S.3
  • 9
    • 0028963022 scopus 로고
    • Preparation and structure of a water-in-oil cream containing lipid nanoparticles
    • T. De Vringer, and H.A.G. De Ronde Preparation and structure of a water-in-oil cream containing lipid nanoparticles J Pharm Sci 84 1995 466 472
    • (1995) J Pharm Sci , vol.84 , pp. 466-472
    • De Vringer, T.1    De Ronde, H.A.G.2
  • 10
    • 0029979358 scopus 로고    scopus 로고
    • Safety of meloxicam: A global analysis of clinical trials
    • M. Distel, C. Mueller, E. Bluhmkij, and J. Fries Safety of meloxicam: a global analysis of clinical trials Br J Rheumatol 35 1996 68 77
    • (1996) Br J Rheumatol , vol.35 , pp. 68-77
    • Distel, M.1    Mueller, C.2    Bluhmkij, E.3    Fries, J.4
  • 12
    • 84857370635 scopus 로고    scopus 로고
    • Nanoemulsions with enhanced temperature stability using thermo-sensitive association of nonionic surfactant and amphiphilic polyelectrolytes
    • J. Galindo-Alvarez, V. Sadtler, P. Marchal, P. Perrin, C. Tribet, and E. Marie Nanoemulsions with enhanced temperature stability using thermo-sensitive association of nonionic surfactant and amphiphilic polyelectrolytes Colloids Surf A: Physicochem Eng 396 2012 115 121
    • (2012) Colloids Surf A: Physicochem Eng , vol.396 , pp. 115-121
    • Galindo-Alvarez, J.1    Sadtler, V.2    Marchal, P.3    Perrin, P.4    Tribet, C.5    Marie, E.6
  • 14
    • 84864123053 scopus 로고    scopus 로고
    • Design and characterization of submicron formulation for a poorly soluble drug: The effect of Vitamin e TPGS and other solubilizers on skin permeability enhancement
    • I. Ghosh, and B. Michniak-Kohn Design and characterization of submicron formulation for a poorly soluble drug: the effect of Vitamin E TPGS and other solubilizers on skin permeability enhancement Int J Pharm 434 2012 90 98
    • (2012) Int J Pharm , vol.434 , pp. 90-98
    • Ghosh, I.1    Michniak-Kohn, B.2
  • 15
    • 84860754420 scopus 로고    scopus 로고
    • Development of a quercetin-loaded nanostructured lipid carrier formulation for topical delivery
    • C.Y. Guo, C.F. Yang, Q.L. Li, Q. Tan, Y.W. Xi, and W.N. Liu Development of a quercetin-loaded nanostructured lipid carrier formulation for topical delivery Int J Pharm 430 2012 292 298
    • (2012) Int J Pharm , vol.430 , pp. 292-298
    • Guo, C.Y.1    Yang, C.F.2    Li, Q.L.3    Tan, Q.4    Xi, Y.W.5    Liu, W.N.6
  • 16
    • 0036190838 scopus 로고    scopus 로고
    • Comparison of analgesic and anti-inflammatory activity of meloxicam gel with diclofenac and piroxicam gels in animal models: Pharmacokinetic parameters after topical application
    • S.K. Gupta, P. Bansal, R.K. Bhardwaj, J. Jaiswal, and T. Velpandian Comparison of analgesic and anti-inflammatory activity of meloxicam gel with diclofenac and piroxicam gels in animal models: pharmacokinetic parameters after topical application Skin Pharmacol Appl Skin Physiol 15 2002 105 111
    • (2002) Skin Pharmacol Appl Skin Physiol , vol.15 , pp. 105-111
    • Gupta, S.K.1    Bansal, P.2    Bhardwaj, R.K.3    Jaiswal, J.4    Velpandian, T.5
  • 17
    • 84869507147 scopus 로고    scopus 로고
    • Nanostructured lipid carriers (NLC) based topical gel of flurbiprofen: Design, characterization and in vivo evaluation
    • F. Han, R. Yin, X. Che, J. Yuan, Y. Cui, and H. Yin Nanostructured lipid carriers (NLC) based topical gel of flurbiprofen: design, characterization and in vivo evaluation Int J Pharm 439 2012 349 357
    • (2012) Int J Pharm , vol.439 , pp. 349-357
    • Han, F.1    Yin, R.2    Che, X.3    Yuan, J.4    Cui, Y.5    Yin, H.6
  • 18
    • 70350183760 scopus 로고    scopus 로고
    • Study on the mechanisms of chitosan and its derivatives used penetration enhancers
    • W. He, X. Guo, L. Xiao, and M. Feng Study on the mechanisms of chitosan and its derivatives used penetration enhancers Int J Pharm 382 2009 234 243
    • (2009) Int J Pharm , vol.382 , pp. 234-243
    • He, W.1    Guo, X.2    Xiao, L.3    Feng, M.4
  • 20
    • 1242338847 scopus 로고    scopus 로고
    • Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
    • K. Jores, W. Mehnert, M. Drechsler, H. Bunjes, C. Johann, and K. Mader Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy J Control Release 95 2004 217 227
    • (2004) J Control Release , vol.95 , pp. 217-227
    • Jores, K.1    Mehnert, W.2    Drechsler, M.3    Bunjes, H.4    Johann, C.5    Mader, K.6
  • 21
    • 36148968932 scopus 로고    scopus 로고
    • Nanostructured lipid carrier (NLC) based gel of celecoxib
    • M. Joshi, and V. Patravale Nanostructured lipid carrier (NLC) based gel of celecoxib Int J Pharm 346 2008 124 132
    • (2008) Int J Pharm , vol.346 , pp. 124-132
    • Joshi, M.1    Patravale, V.2
  • 24
    • 84860512855 scopus 로고    scopus 로고
    • Development of nanostructured lipid carriers (NLC) for controlled delivery of meloxicam
    • S. Khurana, P.M.S. Bedi, and N.K. Jain Development of nanostructured lipid carriers (NLC) for controlled delivery of meloxicam Int J Biomed Nanosci Nanotechnol 1 2010 247 266
    • (2010) Int J Biomed Nanosci Nanotechnol , vol.1 , pp. 247-266
    • Khurana, S.1    Bedi, P.M.S.2    Jain, N.K.3
  • 25
    • 84874109554 scopus 로고    scopus 로고
    • Development of nanostructured lipid carriers (NLC) for controlled delivery of mefenamic acid
    • S. Khurana, P.M.S. Bedi, and N.K. Jain Development of nanostructured lipid carriers (NLC) for controlled delivery of mefenamic acid Int J Biomed Nanosci Nanotechnol 2 2012 232 250
    • (2012) Int J Biomed Nanosci Nanotechnol , vol.2 , pp. 232-250
    • Khurana, S.1    Bedi, P.M.S.2    Jain, N.K.3
  • 26
    • 84874115579 scopus 로고    scopus 로고
    • Nanoemulsion based gel for transdermal delivery of meloxicam: Physico-chemical, mechanistic investigation
    • S. Khurana, N.K. Jain, and P.M.S. Bedi Nanoemulsion based gel for transdermal delivery of meloxicam: physico-chemical, mechanistic investigation Life Sci 92 2013 383 392
    • (2013) Life Sci , vol.92 , pp. 383-392
    • Khurana, S.1    Jain, N.K.2    Bedi, P.M.S.3
  • 27
    • 33947152888 scopus 로고    scopus 로고
    • The effect of meloxicam/ethanolamine salt formation on percutaneous absorption of meloxicam
    • H.M. Ki, and H.K. Choi The effect of meloxicam/ethanolamine salt formation on percutaneous absorption of meloxicam Arch Pharm Res 30 2007 215 221
    • (2007) Arch Pharm Res , vol.30 , pp. 215-221
    • Ki, H.M.1    Choi, H.K.2
  • 28
    • 84855237683 scopus 로고    scopus 로고
    • Electronmicroscopy of nanoemulsions: An essential tool for characterisation and stability assessment
    • V. Klang, N.B. Matsko, C. Valenta, and F. Hofer Electronmicroscopy of nanoemulsions: an essential tool for characterisation and stability assessment Micron 43 2012 85 103
    • (2012) Micron , vol.43 , pp. 85-103
    • Klang, V.1    Matsko, N.B.2    Valenta, C.3    Hofer, F.4
  • 30
    • 11144358243 scopus 로고    scopus 로고
    • Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis
    • W.J. Kraemer, N.A. Ratamess, J.M. Anderson, C.M. Maresh, D.P. Tiberio, and M.E. Joyce Effect of a cetylated fatty acid topical cream on functional mobility and quality of life of patients with osteoarthritis J Rheumatol 31 2004 767 774
    • (2004) J Rheumatol , vol.31 , pp. 767-774
    • Kraemer, W.J.1    Ratamess, N.A.2    Anderson, J.M.3    Maresh, C.M.4    Tiberio, D.P.5    Joyce, M.E.6
  • 31
    • 0034024249 scopus 로고    scopus 로고
    • Baseline risk of gastrointestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin
    • S.F. Lanes, L.A. Rodriguez, and G.E. Hwang Baseline risk of gastrointestinal disorders among new users of meloxicam, ibuprofen, diclofenac, naproxen and indomethacin Pharmacoepidemiol Drug Saf 9 2000 113 117
    • (2000) Pharmacoepidemiol Drug Saf , vol.9 , pp. 113-117
    • Lanes, S.F.1    Rodriguez, L.A.2    Hwang, G.E.3
  • 32
    • 17844406124 scopus 로고    scopus 로고
    • ATR-FTIR spectroscopy: A chemometric approach for studying the lipid organisation of the stratum corneum
    • C. Laugel, N. Yagoubi, and A. Baillet ATR-FTIR spectroscopy: a chemometric approach for studying the lipid organisation of the stratum corneum Chem Phys Lipids 135 2005 55 58
    • (2005) Chem Phys Lipids , vol.135 , pp. 55-58
    • Laugel, C.1    Yagoubi, N.2    Baillet, A.3
  • 33
    • 0031573919 scopus 로고    scopus 로고
    • Percutaneous absorption and histopathology of a poloxamer-based formulation of capsaicin analog
    • B.J. Lee, T.S. Lee, B.J. Cha, S.H. Kim, and W.B. Kim Percutaneous absorption and histopathology of a poloxamer-based formulation of capsaicin analog Int J Pharm 159 1997 105 114
    • (1997) Int J Pharm , vol.159 , pp. 105-114
    • Lee, B.J.1    Lee, T.S.2    Cha, B.J.3    Kim, S.H.4    Kim, W.B.5
  • 34
    • 67349129109 scopus 로고    scopus 로고
    • Thixotropic property in pharmaceutical formulations
    • C.H. Lee, V. Moturi, and Y. Lee Thixotropic property in pharmaceutical formulations J Control Release 136 2009 88 98
    • (2009) J Control Release , vol.136 , pp. 88-98
    • Lee, C.H.1    Moturi, V.2    Lee, Y.3
  • 35
    • 64149094878 scopus 로고    scopus 로고
    • Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery
    • Q. Lv, A. Yu, Y. Xi, H. Li, Z. Song, J. Cui, F. Cao, and G. Zhai Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery Int J Pharm 372 2009 191 198
    • (2009) Int J Pharm , vol.372 , pp. 191-198
    • Lv, Q.1    Yu, A.2    Xi, Y.3    Li, H.4    Song, Z.5    Cui, J.6    Cao, F.7    Zhai, G.8
  • 36
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles. Production, characterization and applications
    • W. Mehnert, and K. Mader Solid lipid nanoparticles. Production, characterization and applications Adv Drug Deliv Rev 47 2001 165 196
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 37
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art
    • R.H. Muller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur J Pharm Biopharm 50 2000 161 177
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 161-177
    • Muller, R.H.1    Mader, K.2    Gohla, S.3
  • 38
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • R.H. Muller, M. Radtke, and S.A. Wissing Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations Adv Drug Deliv Rev 54 2002 S131 S155
    • (2002) Adv Drug Deliv Rev , vol.54
    • Muller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 39
    • 11844281473 scopus 로고    scopus 로고
    • Effect of l-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine
    • S.T.K. Narishetty, and R. Panchagnula Effect of l-menthol and 1,8-cineole on phase behavior and molecular organization of SC lipids and skin permeation of zidovudine J Control Release 102 2005 59 70
    • (2005) J Control Release , vol.102 , pp. 59-70
    • Narishetty, S.T.K.1    Panchagnula, R.2
  • 40
    • 34547905035 scopus 로고    scopus 로고
    • Lipid nanoparticles for improved topical application of drugs for skin diseases
    • M. Schäfer-Korting, W. Mehnert, and H.C. Korting Lipid nanoparticles for improved topical application of drugs for skin diseases Adv Drug Deliv Rev 59 2007 427 443
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 427-443
    • Schäfer-Korting, M.1    Mehnert, W.2    Korting, H.C.3
  • 41
    • 83355166267 scopus 로고    scopus 로고
    • Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs
    • P.P. Shah, P.R. Desai, A.R. Patel, S. Mandip, and M.S. Singh Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs Biomaterials 33 2012 1607 1617
    • (2012) Biomaterials , vol.33 , pp. 1607-1617
    • Shah, P.P.1    Desai, P.R.2    Patel, A.R.3    Mandip, S.4    Singh, M.S.5
  • 42
    • 3242671374 scopus 로고    scopus 로고
    • Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam
    • G. Singh, S. Lanes, and G. Triadafilopoulos Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam Am J Med 117 2004 100 106
    • (2004) Am J Med , vol.117 , pp. 100-106
    • Singh, G.1    Lanes, S.2    Triadafilopoulos, G.3
  • 43
    • 33646574622 scopus 로고    scopus 로고
    • The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents
    • E.B. Souto, and R.H. Muller The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents Pharmazie 6 2006 431 437
    • (2006) Pharmazie , vol.6 , pp. 431-437
    • Souto, E.B.1    Muller, R.H.2
  • 44
    • 0032956744 scopus 로고    scopus 로고
    • Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations
    • T.M. Suhonen, J.A. Bouwstra, and A. Urtti Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations J Control Release 59 1999 149 161
    • (1999) J Control Release , vol.59 , pp. 149-161
    • Suhonen, T.M.1    Bouwstra, J.A.2    Urtti, A.3
  • 45
    • 34250893864 scopus 로고    scopus 로고
    • Cetyl palmitate-based NLC for topical delivery of coenzyme Q10-development, physicochemical characterization and in vitro release studies
    • V. Teeranachaideekul, E.B. Souto, V.B. Junyaprasert, H. Rainer, and R.H. Muller Cetyl palmitate-based NLC for topical delivery of coenzyme Q10-development, physicochemical characterization and in vitro release studies Eur J Pharm Biopahrm 67 2007 141 148
    • (2007) Eur J Pharm Biopahrm , vol.67 , pp. 141-148
    • Teeranachaideekul, V.1    Souto, E.B.2    Junyaprasert, V.B.3    Rainer, H.4    Muller, R.H.5
  • 46
    • 28444443300 scopus 로고    scopus 로고
    • Solid lipid nanoparticles
    • N.K. Jain, CBS Publishers and Distributors New Delhi
    • S. Utreja, and N.K. Jain Solid lipid nanoparticles N.K. Jain, Advances in controlled and novel drug delivery 2001 CBS Publishers and Distributors New Delhi 408 425
    • (2001) Advances in Controlled and Novel Drug Delivery , pp. 408-425
    • Utreja, S.1    Jain, N.K.2
  • 47
    • 0032805535 scopus 로고    scopus 로고
    • Lipoprotein-mimicking biovectorized systems for methotrexate delivery
    • S. Utreja, A.J. Khopade, and N.K. Jain Lipoprotein-mimicking biovectorized systems for methotrexate delivery Pharm Acta Helv 73 1999 275 279
    • (1999) Pharm Acta Helv , vol.73 , pp. 275-279
    • Utreja, S.1    Khopade, A.J.2    Jain, N.K.3
  • 48
    • 0024317312 scopus 로고
    • Evaluation of the non-sink dialysis method for the measurement of drug release from colloids effect of drug partition
    • C. Washington Evaluation of the non-sink dialysis method for the measurement of drug release from colloids effect of drug partition Int J Pharm 56 1989 71 74
    • (1989) Int J Pharm , vol.56 , pp. 71-74
    • Washington, C.1
  • 49
    • 0029923125 scopus 로고    scopus 로고
    • Skin corrosivity potential of fatty acids: In vitro rat and human skin testing and QSAR studies
    • E. Whittle, M.D. Barratt, J.A. Carter, D.A. Basketter, and M. Chamberlain Skin corrosivity potential of fatty acids: in vitro rat and human skin testing and QSAR studies Toxicol In Vitro 10 1996 95 100
    • (1996) Toxicol in Vitro , vol.10 , pp. 95-100
    • Whittle, E.1    Barratt, M.D.2    Carter, J.A.3    Basketter, D.A.4    Chamberlain, M.5
  • 51
    • 0029128104 scopus 로고
    • Interaction of phosphatidylcholine liposomes with the human stratum corneum
    • S. Zellmer, W. Pfeil, and J. Lasch Interaction of phosphatidylcholine liposomes with the human stratum corneum Biochim Biophys Acta 1237 1995 176 182
    • (1995) Biochim Biophys Acta , vol.1237 , pp. 176-182
    • Zellmer, S.1    Pfeil, W.2    Lasch, J.3


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