Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation

Journal of Biological Chemistry

Volumn 287, Issue 36, 2012, Pages 30701-30710

  Zhang, Long ^a   Zhou, Fangfang ^a   Li, Yihao ^a   Drabsch, Yvette ^a   Zhang, Juan ^a   Van Dam, Hans ^a   Ten Dijke, Peter ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER CELLS; BREAST TISSUES; CATENIN DEGRADATION; CATENIN SIGNALING; E-CADHERINS; EPITHELIAL TO MESENCHYMAL TRANSITIONS; HUMAN BREAST; HUMAN BREAST CANCER CELLS; IN-VITRO; IN-VIVO; MCF-7 CELLS; MOLECULAR MECHANISM; POLYUBIQUITINATION; SCAFFOLD PROTEIN; TRANSDUCIN; UBIQUITIN LIGASES; UBIQUITINATION; VIMENTIN; WNT SIGNALING;

CELLS; DEGRADATION; PROTEINS; SIGNALING; TISSUE;

SCAFFOLDS (BIOLOGY);

BETA CATENIN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; FAS ASSOCIATED FACTOR 1; SCAFFOLD PROTEIN; SKP1 CUL1 F BOX PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER INVASION; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; DATA MINING; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UBIQUITINATION; ZEBRA FISH;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BETA CATENIN; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; BREAST NEOPLASMS; CADHERINS; CELL MOVEMENT; CULLIN PROTEINS; FEMALE; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HELA CELLS; HUMANS; PROTEOLYSIS; S-PHASE KINASE-ASSOCIATED PROTEINS; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION; WNT SIGNALING PATHWAY;

EID: 84865712651     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353524     Document Type: Article

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