The enhanced immune response of hepatitis B virus DNA vaccine using SiO2@LDH nanoparticles as an adjuvant

Biomaterials

Volumn 35, Issue 1, 2014, Pages 466-478

  Wang, Jin ^a   Zhu, Rongrong ^a   Gao, Bo ^a   Wu, Bin ^a   Li, Kun ^a   Sun, Xiaoyu ^a   Liu, Hui ^b   Wang, Shilong ^a  

^a TONGJI UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adjuvant; DNA vaccine; Hepatitis B surface antigen; Immunology; Layered double hydroxides; Macrophages

Indexed keywords

ADJUVANT; CORE SHELL STRUCTURE; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; LAYERED DOUBLE HYDROXIDES; NON-VIRAL GENE DELIVERY; PROTECTIVE IMMUNITIES; TRANSFECTION EFFICIENCY;

CELL PROLIFERATION; GENE TRANSFER; IMMUNE SYSTEM; IMMUNOLOGY; MACROPHAGES; NANOPARTICLES; T-CELLS; VACCINES; VIRUSES;

SYNTHESIS (CHEMICAL);

CD86 ANTIGEN; DNA VACCINE; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; HYDROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LAYERED DOUBLE HYDROXIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NANOPARTICLE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA IMMUNIZATION; DOSE RESPONSE; FEMALE; HEPATITIS B; HEPATITIS B VIRUS; IMMUNE RESPONSE; IMMUNIZATION; MACROPHAGE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL;

HEPATITIS B VIRUS; MUS;

ADJUVANT; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; IMMUNOLOGY; LAYERED DOUBLE HYDROXIDES; MACROPHAGES;

ADJUVANTS, IMMUNOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOKINES; ENDOCYTOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HEPATITIS B VACCINES; HUMANS; HYDROXIDES; MACROPHAGES; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; SILICON DIOXIDE; VACCINES, DNA;

EID: 84887022044     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.09.060     Document Type: Article

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