Enhancement of humoral and cellular responses to HBsAg DNA vaccination by immunization with praziquantel through inhibition TGF-β/Smad2,3 signaling

Vaccine

Volumn 28, Issue 8, 2010, Pages 2032-2038

  Zou, Qiang ^a   Zhong, Yiwei ^a   Su, Hairui ^a   Kang, Youmin ^a   Jin, Jin ^a   Liu, Qiang ^a   Geng, Shuang ^a   Zhao, Gan ^a   Wang, Bin ^a  

^a College of Biological Sciences   (China)

Author keywords

Adjuvant; Cellular immune responses; HBV DNA vaccine; In vivo CTL; Praziquantel; Regulatory T cell

Indexed keywords

BETA ACTIN; DNA VACCINE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; PRAZIQUANTEL; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ADJUVANT THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DNA IMMUNIZATION; DOWN REGULATION; DRUG EFFECT; FEMALE; HUMORAL IMMUNITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOREGULATION; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL PROLIFERATION; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; GENE EXPRESSION REGULATION; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNOGLOBULIN G; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED C57BL; PRAZIQUANTEL; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA; VACCINES, DNA;

EID: 76949094664     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.10.101     Document Type: Article

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