Intranasal delivery of cationic PLGA nano/microparticles- loaded fmdv DNA vaccine encoding IL-6 elicited protective immunity against FMDV challenge

PLoS ONE

Volumn 6, Issue 11, 2011, Pages

  Wang, Gang ^a   Pan, Li ^a   Zhang, Yongguang ^a   Wang, Yonglu ^a   Zhang, Zhongwang ^a   Lü, Jianliang ^a   Zhou, Peng ^a   Fang, Yuzhen ^a   Jiang, Shoutian ^a  

^a INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; CATION; CHITOSAN; DNA VACCINE; FOOT AND MOUTH DISEASE VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 6; NANOPARTICLE; NEUTRALIZING ANTIBODY; POLYGLACTIN; SECRETORY IMMUNOGLOBULIN; VIRUS ANTIGEN; CYTOKINE; DRUG CARRIER; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TRANSCRIPTOME; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; EUKARYOTE; FEMALE; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE; GENE LOCATION; IL 6 GENE; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; NONHUMAN; PLASMID; PROTEIN EXPRESSION; RAT; SPLEEN CELL; T LYMPHOCYTE; VACCINATION; VIRUS ASSEMBLY; VIRUS CAPSID; ANIMAL; BIOSYNTHESIS; BLOOD; CATTLE; CHEMISTRY; CYTOLOGY; DENDRITIC CELL; DRUG EFFECT; GENETICS; GUINEA PIG; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; METABOLISM; MICROTECHNOLOGY; MUCOSA;

ANIMALIA; BOVINAE; CAVIA; EUKARYOTA; FOOT-AND-MOUTH DISEASE VIRUS; MIRIDAE; RATTUS;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, NEUTRALIZING; CAPSID PROTEINS; CATTLE; CHITOSAN; CYTOKINES; DENDRITIC CELLS; DRUG CARRIERS; FEMALE; FOOT-AND-MOUTH DISEASE VIRUS; GUINEA PIGS; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; INTERLEUKIN-6; LACTIC ACID; MICROTECHNOLOGY; MUCOUS MEMBRANE; NANOPARTICLES; PLASMIDS; POLYGLYCOLIC ACID; RATS; T-LYMPHOCYTES; TRANSCRIPTOME; VACCINES, DNA; VIRAL VACCINES;

EID: 81155125702     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027605     Document Type: Article

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