Regulation of prostaglandin F2α against β amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia

Prostaglandins and Other Lipid Mediators

Volumn 106, Issue , 2013, Pages 45-52

  Zhuang, Jingjing ^a   Zhang, Haikun ^a   Zhou, Rong ^a   Chen, Lili ^b   Chen, Jing ^b   Shen, Xu ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

A clearance; Alzheimer's disease; Inflammation; Microglia; Prostaglandin F2

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; DIMER; DRUG METABOLITE; HETERODIMER; LIPOPOLYSACCHARIDE; LIVER X RECEPTOR; PROSTAGLANDIN F2 ALPHA; RETINOID X RECEPTOR ALPHA; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); FLUORINATED HYDROCARBON; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; ORPHAN NUCLEAR RECEPTOR; PEPTIDE FRAGMENT; RETINOID X RECEPTOR; SULFONAMIDE; TO-901317;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; MICROGLIA; PROMOTER REGION; PROTEIN EXPRESSION; AΒ CLEARANCE; CELL LINE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; PROSTAGLANDIN F(2Α); PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE;

AΒ CLEARANCE; ALZHEIMER'S DISEASE; INFLAMMATION; MICROGLIA; PROSTAGLANDIN F(2Α);

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; CELL LINE; DINOPROST; GENE EXPRESSION REGULATION; HUMANS; HYDROCARBONS, FLUORINATED; INFLAMMATION; MICROGLIA; ORPHAN NUCLEAR RECEPTORS; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; RETINOID X RECEPTORS; SULFONAMIDES;

EID: 84886907869     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2013.09.002     Document Type: Article

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