Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis

Journal of Biological Chemistry

Volumn 288, Issue 42, 2013, Pages 30399-30410

  Cao, Huiling ^a   Zhu, Ke ^a,b   Qiu, Lugui ^c   Li, Shuai ^a   Niu, Hanjie ^a   Hao, Mu ^c   Yang, Shengyong ^d   Zhao, Zhongfang ^a   Lai, Yumei ^b   Anderson, Judith L ^e   Fan, Jie ^d   Im, Hee Jeong ^b   Chen, Di ^b   Roodman, G David ^e   Xiao, Guozhi ^a,b  

^a NANKAI UNIVERSITY   (China)

^b RUSH UNIVERSITY   (United States)

^c INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE DISEASE; MYELOMA CELL; OSTEOCLAST FORMATION; OSTEOCLAST PRECURSOR; OSTEOLYSIS; TUMOR GROWTH;

BIOCHEMISTRY; BIOLOGY;

BONE;

2 MORPHOLINO 8 PHENYLCHROMONE; ACTIVATING TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; CANCER TISSUE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; MALE; MONOCYTE; MOUSE; MULTIPLE MYELOMA; MYELOMA CELL; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCID MOUSE; UPREGULATION;

AKT; BONE; METASTASIS; OSTEOCLAST; TRANSCRIPTION FACTORS;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; CHROMONES; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HETEROGRAFTS; HUMANS; MALE; MICE; MICE, SCID; MORPHOLINES; MULTIPLE MYELOMA; NEOPLASM TRANSPLANTATION; OSTEOCLASTS; OSTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 84886878565     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.469973     Document Type: Article

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