Metabolomics uncovers dietary omega-3 fatty acid-derived metabolites implicated in anti-nociceptive responses after experimental spinal cord injury

Neuroscience

Volumn 255, Issue , 2013, Pages 1-18

  Figueroa, J D ^a   Cordero, K ^a   Serrano Illan, M ^a   Almeyda, A ^a   Baldeosingh, K ^a   Almaguel, F G ^a,b   De Leon, M ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

Chronic pain; DHA; Dietary fatty acids; Endocannabinoid metabolome; EPA; Spinal cord injury

Indexed keywords

BIOLOGICAL MARKER; CALCITONIN GENE RELATED PEPTIDE; DOCOSAHEXAENOIC ACID; DOCOSAPENTAENOYL ETHANOLAMINE; EICOSAPENTAENOYL ETHANOLAMINE; ENDOCANNABINOID; GLYCEROPHOSPHO CONTAINING DOCOSAHEXAENOYL ETHANOLAMINE; INOSITOL; MITOGEN ACTIVATED PROTEIN KINASE P38; N ACYLETHANOLAMINE; OMEGA 3 FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DIET THERAPY; EXPERIMENTAL TEST; FAT INTAKE; FEMALE; HARGREAVES TEST; HOT PLATE TEST; HYPERALGESIA; LIPID METABOLISM; LIPID STORAGE; METABOLITE; METABOLOMICS; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; TISSUE LEVEL;

1-OG; 1-OLEOYL GLYCEROL; 2-AG; 2-ARACHIDONOYL GLYCEROL; 2-PALMITOYL GLYCEROL; 2-PG; ABH4; AEA; ARACHIDONOYL ETHANOLAMINE; BASSO, BEATTIE AND BRESNAHAN; BBB; CALCITONIN GENE-RELATED PEPTIDE; CGRP; CHRONIC PAIN; DHA; DHEA; DIETARY FATTY ACIDS; DOCOSAHEXAENOIC ACID; DOCOSAHEXAENOYL ETHANOLAMINE/SYNAPTAMIDE; DOCOSAPENTAENOYL ETHANOLAMINE; DPEA; ECBS; EG; EICOSAPENTAENOYL ETHANOLAMINE; EICOSENOYL GLYCEROL; ENDOCANNABINOID METABOLOME; ENDOCANNABINOIDS; EPA; EPEA; G3P; GAP43; GAS CHROMATOGRAPHY/MASS SPECTROMETRY; GC/MS; GDE1; GLYCEROL-3-PHOSPHATE; GLYCEROPHOSPHO-CONTAINING N-ACYL ETHANOLAMINES; GLYCEROPHOSPHODIESTERASE; GP-NAES; GROWTH-ASSOCIATED PROTEIN 43; HINDPAW WITHDRAWAL LATENCY; HWL; LEA; LINOLEYL ETHANOLAMINE; LPA; LYSO-PHOSPHATIDIC ACID; MAPK; MITOGEN-ACTIVATED PROTEIN KINASE; N-ACYL ETHANOLAMINES; N-ACYL PHOSPHATIDYL ETHANOLAMINE; NAES; NAPE; O3PUFAS; OMEGA-3 POLYUNSATURATED FATTY ACIDS; PA; PALMITOYL ETHANOLAMINE; PARTIAL LEAST SQUARE-DISCRIMINANT ANALYSIS; PEA; PHOSPHATIDIC ACID; PHOSPHOLIPASE A/B OR Α-Β-HYDROLASE 4; PHOSPHOLIPASE D; PLD; PLS-DA; SCI; SPINAL CORD INJURY; TH; THERMAL HYPERALGESIA; UHPLC/MS/MS(2); ULTRAHIGH PERFORMANCE LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIETARY FATS; DISEASE MODELS, ANIMAL; FATTY ACIDS, OMEGA-3; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HYPERALGESIA; METABOLOMICS; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD INJURIES; TANDEM MASS SPECTROMETRY;

EID: 84886789799     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.09.012     Document Type: Article

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