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Volumn 28, Issue 8, 2011, Pages 1589-1610

A systematic review of directly applied biologic therapies for acute spinal cord injury

Author keywords

anti nogo antibodies; biologic therapies; cethrin; chondroitinase ABC; spinal cord injury

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CETHRIN; CHONDROITIN ABC LYASE; EXOENZYME C3; FASUDIL; FIBRIN GLUE; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; LITHIUM CHLORIDE; MONOCLONAL ANTIBODY; MYELIN; NOGO 66 RECEPTOR; NOGO A ANTIBODY; PENICILLINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VIMENTIN;

EID: 79960803845     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2009.1150     Document Type: Review
Times cited : (87)

References (61)
  • 1
  • 3
    • 14744306466 scopus 로고    scopus 로고
    • Chondroitinase ABCI improves locomotion and bladder function following contusion injury of the rat spinal cord
    • Caggiano, A.O., Zimber, M.P., Ganguly, A., Blight, A.R., and Gruskin, E.A. (2005). Chondroitinase ABCI improves locomotion and bladder function following contusion injury of the rat spinal cord. J. Neurotrauma 22, 226-239. (Pubitemid 40333517)
    • (2005) Journal of Neurotrauma , vol.22 , Issue.2 , pp. 226-239
    • Caggiano, A.O.1    Zimber, M.P.2    Ganguly, A.3    Blight, A.R.4    Gruskin, E.A.5
  • 4
    • 58149385768 scopus 로고    scopus 로고
    • The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury
    • Carter, L.M., Starkey, M.L., Akrimi, S.F., Davies, M., McMahon, S.B., and Bradbury, E.J. (2008). The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury. J. Neurosci. 28, 14107-14120.
    • (2008) J. Neurosci. , vol.28 , pp. 14107-14120
    • Carter, L.M.1    Starkey, M.L.2    Akrimi, S.F.3    Davies, M.4    McMahon, S.B.5    Bradbury, E.J.6
  • 5
    • 1342268329 scopus 로고    scopus 로고
    • Chondroitinase ABC enhances axonal regrowth through Schwann cell-seeded guidance channels after spinal cord injury
    • Chau, C.H., Shum, D.K., Li, H., Pei, J., Lui, Y.Y., Wirthlin, L., Chan, Y.S., and Xu, X.M. (2004). Chondroitinase ABC enhances axonal regrowth through Schwann cell-seeded guidance channels after spinal cord injury. FASEB J. 18, 194-196.
    • (2004) FASEB J. , vol.18 , pp. 194-196
    • Chau, C.H.1    Shum, D.K.2    Li, H.3    Pei, J.4    Lui, Y.Y.5    Wirthlin, L.6    Chan, Y.S.7    Xu, X.M.8
  • 6
    • 70349748600 scopus 로고    scopus 로고
    • Transplantation and repair: Combined cell implantation and chondroitinase delivery prevents deterioration of bladder function in rats with complete spinal cord injury
    • Fouad, K., Pearse, D.D., Tetzlaff, W., and Vavrek, R. (2009). Transplantation and repair: combined cell implantation and chondroitinase delivery prevents deterioration of bladder function in rats with complete spinal cord injury. Spinal Cord 47, 727-732.
    • (2009) Spinal Cor , vol.47 , pp. 727-732
    • Fouad, K.1    Pearse, D.D.2    Tetzlaff, W.3    Vavrek, R.4
  • 7
    • 13944266687 scopus 로고    scopus 로고
    • Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord
    • DOI 10.1523/JNEUROSCI.3562-04.2005
    • Fouad, K., Schnell, L., Bunge, M.B., Schwab, M.E., Liebscher, T., and Pearse, D.D. (2005). Combining Schwann cell bridges and olfactory-ensheathing glia grafts with chondroitinase promotes locomotor recovery after complete transection of the spinal cord. J. Neurosci. 25, 1169-1178. (Pubitemid 40268958)
    • (2005) Journal of Neuroscience , vol.25 , Issue.5 , pp. 1169-1178
    • Fouad, K.1    Schnell, L.2    Bunge, M.B.3    Schwab, M.E.4    Liebscher, T.5    Pearse, D.D.6
  • 8
    • 41149164275 scopus 로고    scopus 로고
    • Therapeutic time window for the application of chondroitinase ABC after spinal cord injury
    • García-Alías, G., Lin, R., Akrimi, S.F., Story, D., Bradbury, E.J., and Fawcett, J.W. (2007). Therapeutic time window for the application of chondroitinase ABC after spinal cord injury. Exp. Neurol. 210, 402-408.
    • (2007) Exp. Neurol. , vol.210 , pp. 402-408
    • García-Alías, G.1    Lin, R.2    Akrimi, S.F.3    Story, D.4    Bradbury, E.J.5    Fawcett, J.W.6
  • 9
    • 33746094328 scopus 로고    scopus 로고
    • Combining an autologous peripheral nervous system "bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord
    • DOI 10.1523/JNEUROSCI.1166-06.2006
    • Houle, J.D., Tom, V.J., Mayes, D., Wagoner, G., Phillips, N., and Silver, J. (2006). Combining an autologous peripheral nervous system "bridge" and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the adult rat spinal cord. J. Neurosci. 26, 7405-7415. (Pubitemid 44315209)
    • (2006) Journal of Neuroscience , vol.26 , Issue.28 , pp. 7405-7415
    • Houle, J.D.1    Tom, V.J.2    Mayes, D.3    Wagoner, G.4    Phillips, N.5    Silver, J.6
  • 11
    • 39449134309 scopus 로고    scopus 로고
    • Chondroitin sulfate proteoglycans in spinal cord contusion injury and the effects of chondroitinase treatment
    • DOI 10.1089/neu.2007.0366
    • Iaci, J.F., Vecchione, A.M., Zimber, M.P., and Caggiano, A.O. (2007). Chondroitin sulfate proteoglycans in spinal cord contusion injury and the effects of chondroitinase treatment. J. Neurotrauma 24, 1743-1759. (Pubitemid 351267795)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.11 , pp. 1743-1759
    • Iaci, J.F.1    Vecchione, A.M.2    Zimber, M.P.3    Caggiano, A.O.4
  • 12
    • 29344451629 scopus 로고    scopus 로고
    • Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury
    • DOI 10.1111/j.1460-9568.2005.04492.x
    • Ikegami, T., Nakamura, M., Yamane, J., Katoh, H., Okada, S., Iwanami, A., Watanabe, K., Ishii, K., Kato, F., Fujita, H., Takahashi, T., Okano, H.J., Toyama, Y., and Okano, H. (2005). Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. Eur. J. Neurosci. 22, 3036-3046. (Pubitemid 43001987)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.12 , pp. 3036-3046
    • Ikegami, T.1    Nakamura, M.2    Yamane, J.3    Katoh, H.4    Okada, S.5    Iwanami, A.6    Watanabe, K.7    Ishii, K.8    Kato, F.9    Fujita, H.10    Takahashi, T.11    Okano, H.J.12    Toyama, Y.13    Okano, H.14
  • 13
    • 41449105151 scopus 로고    scopus 로고
    • Single, high-dose intraspinal injection of chondroitinase reduces glycosaminoglycans in injured spinal cord and promotes corticospinal axonal regrowth after hemisection but not contusion
    • DOI 10.1089/neu.2007.0289
    • Iseda, T., Okuda, T., Kane-Goldsmith, N., Mathew, M., Ahmed, S., Chang, Y.W., Young, W., and Grumet, M. (2008). Single, high-dose intraspinal injection of chondroitinase reduces glycosaminoglycans in injured spinal cord and promotes corticospinal axonal regrowth after hemisection but not contusion. J. Neurotrauma 25, 334-349. (Pubitemid 351457758)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.4 , pp. 334-349
    • Iseda, T.1    Okuda, T.2    Kane-Goldsmith, N.3    Mathew, M.4    Ahmed, S.5    Chang, Y.-W.6    Young, W.7    Grumet, M.8
  • 14
    • 33744733410 scopus 로고    scopus 로고
    • Degradation of chondroitin sulfate proteoglycans potentiates transplant-mediated axonal remodeling and functional recovery after spinal cord injury in adult rats
    • DOI 10.1002/cne.20980
    • Kim, B.G., Dai, H.N., Lynskey, J.V., McAtee, M., and Bregman, B.S. (2006). Degradation of chondroitin sulfate proteoglycans potentiates transplant-mediated axonal remodeling and functional recovery after spinal cord injury in adult rats. J. Comp. Neurol. 497, 182-198. (Pubitemid 43825426)
    • (2006) Journal of Comparative Neurology , vol.497 , Issue.2 , pp. 182-198
    • Kim, B.G.1    Dai, H.-N.2    Lynskey, J.V.3    McAtee, M.4    Bregman, B.S.5
  • 15
    • 38649124935 scopus 로고    scopus 로고
    • Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3
    • DOI 10.1016/j.expneurol.2007.03.029, PII S0014488607001367
    • Massey, J.M., Amps, J., Viapiano, M.S., Matthews, R.T., Wagoner, M.R., Whitaker, C.M., Alilain, W., Yonkof, A.L., Khalyfa, A., Cooper, N.G., Silver, J., and Onifer, S.M. (2008). Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3. Exp. Neurol. 209, 426-445. (Pubitemid 351174125)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 426-445
    • Massey, J.M.1    Amps, J.2    Viapiano, M.S.3    Matthews, R.T.4    Wagoner, M.R.5    Whitaker, C.M.6    Alilain, W.7    Yonkof, A.L.8    Khalyfa, A.9    Cooper, N.G.F.10    Silver, J.11    Onifer, S.M.12
  • 16
    • 33646442052 scopus 로고    scopus 로고
    • Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury
    • DOI 10.1523/JNEUROSCI.5467-05.2006
    • Massey, J.M., Hubscher, C.H., Wagoner, M.R., Decker, J.A., Amps, J., Silver, J., and Onifer, S.M. (2006). Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury. J. Neurosci. 26, 4406-4414. (Pubitemid 44315399)
    • (2006) Journal of Neuroscience , vol.26 , Issue.16 , pp. 4406-4414
    • Massey, J.M.1    Hubscher, C.H.2    Wagoner, M.R.3    Decker, J.A.4    Amps, J.5    Silver, J.6    Onifer, S.M.7
  • 17
    • 43449101472 scopus 로고    scopus 로고
    • Benefit of chondroitinase ABC on sensory axon regeneration in a laceration model of spinal cord injury in the rat
    • DOI 10.1016/j.surneu.2008.02.009, PII S0090301908001456
    • Shields, L.B., Zhang, Y.P., Burke, D.A., Gray, R., and Shields, C.B. (2008). Benefit of chondroitinase ABC on sensory axon regeneration in a laceration model of spinal cord injury in the rat. Surg. Neurol. 69, 568-577. (Pubitemid 351671849)
    • (2008) Surgical Neurology , vol.69 , Issue.6 , pp. 568-577
    • Shields, L.B.E.1    Zhang, Y.P.2    Burke, D.A.3    Gray, R.4    Shields, C.B.5
  • 18
    • 33646926966 scopus 로고    scopus 로고
    • Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord
    • DOI 10.1523/JNEUROSCI.3900-05.2006
    • Tan, A.M., Colletti, M., Rorai, A.T., Skene, J.H., and Levine, J.M. (2006). Antibodies against the NG2 proteoglycan promote the regeneration of sensory axons within the dorsal columns of the spinal cord. J. Neurosci. 26, 4729-4739. (Pubitemid 44315312)
    • (2006) Journal of Neuroscience , vol.26 , Issue.18 , pp. 4729-4739
    • Tan, A.M.1    Colletti, M.2    Rorai, A.T.3    Skene, J.H.P.4    Levine, J.M.5
  • 19
    • 38649143667 scopus 로고    scopus 로고
    • Chondroitinase ABC improves basic and skilled locomotion in spinal cord injured cats
    • DOI 10.1016/j.expneurol.2007.07.019, PII S0014488607002981
    • Tester, N.J., and Howland, D.R. (2008). Chondroitinase ABC improves basic and skilled locomotion in spinal cord injured cats. Exp. Neurol. 209, 483-496. (Pubitemid 351174137)
    • (2008) Experimental Neurology , vol.209 , Issue.2 , pp. 483-496
    • Tester, N.J.1    Howland, D.R.2
  • 20
    • 42749092831 scopus 로고    scopus 로고
    • Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft bridge
    • Tom, V., and Houlé, J.D. (2008). Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft bridge. Exp. Neurol. 211, 315-319.
    • (2008) Exp. Neurol. , vol.211 , pp. 315-319
    • Tom, V.1    Houlé, J.D.2
  • 21
    • 35649017602 scopus 로고    scopus 로고
    • Neuronal populations capable of regeneration following a combined treatment in rats with spinal cord transection
    • DOI 10.1089/neu.2007.0290
    • Vavrek, R., Pearse, D.D., and Fouad, K. (2007). Neuronal populations capable of regeneration following a combined treatment in rats with spinal cord transection. J. Neurotrauma 24, 1667-1673. (Pubitemid 350035836)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.10 , pp. 1667-1673
    • Vavrek, R.1    Pearse, D.D.2    Fouad, K.3
  • 22
    • 3242879990 scopus 로고    scopus 로고
    • Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury
    • Yick, L.W., So, K.F., Cheung, P.T., and Wu, W.T. (2004). Lithium chloride reinforces the regeneration-promoting effect of chondroitinase ABC on rubrospinal neurons after spinal cord injury. J. Neurotrauma 21, 932-943.
    • (2004) J. Neurotraum , vol.21 , pp. 932-943
    • Yick, L.W.1    So, K.F.2    Cheung, P.T.3    Wu, W.T.4
  • 23
    • 0037757588 scopus 로고    scopus 로고
    • Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC
    • DOI 10.1016/S0014-4886(02)00052-3
    • Yick, L.W., Cheung, P.T., So, K.F., and Wu, W. (2003). Axonal regeneration of Clarke's neurons beyond the spinal cord injury scar after treatment with chondroitinase ABC. Exp. Neurol. 182, 160-168. (Pubitemid 36776259)
    • (2003) Experimental Neurology , vol.182 , Issue.1 , pp. 160-168
    • Yick, L.-W.1    Cheung, P.-T.2    So, K.-F.3    Wu, W.4
  • 24
    • 0000137795 scopus 로고    scopus 로고
    • Chondroitinase ABC promotes axonal regeneration of Clarke's neurons after spinal cord injury
    • Yick, L.W., Wu, W., So, K.F., Yip, H.K., Shum, D.K., (2000). Chondroitinase ABC promotes axonal regeneration of Clarke's neurons after spinal cord injury. Neuroreport. 11, 1063-1067. (Pubitemid 30235456)
    • (2000) NeuroReport , vol.11 , Issue.5 , pp. 1063-1067
    • Yick, L.-W.1    Wu, W.2    So, K.-F.3    Yip, H.K.4    Shum, D.K.-Y.5
  • 25
    • 55549096356 scopus 로고    scopus 로고
    • Antisense vimentin cDNA combined with chondroitinase ABC reduces glial scar and cystic cavity formation following spinal cord injury in rats
    • Xia, Y., Zhao, T., Li, J., Li, L., Hu, R., Hu, S., Feng, H., and Lin, J. (2008). Antisense vimentin cDNA combined with chondroitinase ABC reduces glial scar and cystic cavity formation following spinal cord injury in rats. Biochem. Biophys. Res. Commun. 377, 562-566.
    • (2008) Biochem. Biophys. Res. Commun. , vol.377 , pp. 562-566
    • Xia, Y.1    Zhao, T.2    Li, J.3    Li, L.4    Hu, R.5    Hu, S.6    Feng, H.7    Lin, J.8
  • 26
    • 36849012627 scopus 로고    scopus 로고
    • Antibodies neutralizing Nogo-A increase pan-cadherin expression and motor recovery following spinal cord injury in rats
    • DOI 10.1038/sj.sc.3102113, PII 3102113
    • Atalay, B., Bavbek, M., Cekinmez, M., Ozen, O., Nacar, A., Karabay, G., and Gulsen, S. (2007). Antibodies neutralizing Nogo-A increase pan-cadherin expression and motor recovery following spinal cord injury in rats. Spinal Cord 45, 780-786. (Pubitemid 350224262)
    • (2007) Spinal Cord , vol.45 , Issue.12 , pp. 780-786
    • Atalay, B.1    Bavbek, M.2    Cekinmez, M.3    Ozen, O.4    Nacar, A.5    Karabay, G.6    Gulsen, S.7
  • 27
    • 39149112820 scopus 로고    scopus 로고
    • Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion
    • doi:10.1186=1471-2202-9-5
    • Beaud, M.L., Schmidlin, E.,Wannier, T., Freund, P., Bloch, J., Mir, A., Schwab, M.E., and Rouiller, E.M. (2008). Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC Neurosci. 9, doi:10.1186=1471-2202-9-5.
    • (2008) BMC Neurosci. , vol.9
    • Beaud, M.L.1    Schmidlin, E.2    Wannier, T.3    Freund, P.4    Bloch, J.5    Mir, A.6    Schwab, M.E.7    Rouiller, E.M.8
  • 28
    • 0028867947 scopus 로고
    • Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
    • Bregman, B.S., Kunkel-Bagden, E., Schnell, L., Dai, H.N., Gao, D., and Schwab, M.E. (1995). Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors. Nature 378, 498-501.
    • (1995) Nature , vol.378 , pp. 498-501
    • Bregman, B.S.1    Kunkel-Bagden, E.2    Schnell, L.3    Dai, H.N.4    Gao, D.5    Schwab, M.E.6
  • 29
    • 0034331170 scopus 로고    scopus 로고
    • Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment
    • Brosamle, C., Huber, A.B., Fiedler, M., Skerra, A., and Schwab, M.E. (2000). Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J. Neurosci. 20, 8061-8068.
    • (2000) J. Neurosci. , vol.20 , pp. 8061-8068
    • Brosamle, C.1    Huber, A.B.2    Fiedler, M.3    Skerra, A.4    Schwab, M.E.5
  • 30
    • 42449104410 scopus 로고    scopus 로고
    • Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat
    • DOI 10.1177/1545968307308550
    • Cao, Y., Shumsky, J.S., Sabol, M.A., Kushner, R.A., Strittmatter, S., Hamers, F.P., Lee, D.H., Rabacchi, S.A., and Murray, M. (2008). Nogo-66 receptor antagonist peptide (NEP1-40) administration promotes functional recovery and axonal growth after lateral funiculus injury in the adult rat. Neurorehabil. Neural Repair 22, 262-278. (Pubitemid 351561674)
    • (2008) Neurorehabilitation and Neural Repair , vol.22 , Issue.3 , pp. 262-278
    • Cao, Y.1    Shumsky, J.S.2    Sabol, M.A.3    Kushner, R.A.4    Strittmatter, S.5    Hamers, F.P.T.6    Lee, D.H.S.7    Rabacchi, S.A.8    Murray, M.9
  • 31
    • 8144228423 scopus 로고    scopus 로고
    • Regenerating corticospinal fibers in the Marmoset (Callitrix jacchus) after spinal cord lesion and treatment with the anti-Nogo-A antibody IN-1
    • DOI 10.1111/j.1460-9568.2004.03716.x
    • Fouad, K., Klusman, I., and Schwab, M.E. (2004). Regenerating corticospinal fibers in the Marmoset (Callitrix jacchus) after spinal cord lesion and treatment with the anti-Nogo-A antibody IN-1. Eur. J. Neurosci. 20, 2479-2482. (Pubitemid 39472410)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.9 , pp. 2479-2482
    • Fouad, K.1    Klusman, I.2    Schwab, M.E.3
  • 32
    • 61449199550 scopus 로고    scopus 로고
    • Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates-re-examination and extension of behavioral dat
    • Freund, P., Schmidlin, E., Wannier, T., Bloch, J., Mir, A., Schwab, M.E., and Rouiller, E.M. (2009). Anti-Nogo-A antibody treatment promotes recovery of manual dexterity after unilateral cervical lesion in adult primates-re- examination and extension of behavioral data. Eur. J. Neurosci. 29, 983-996.
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 983-996
    • Freund, P.1    Schmidlin, E.2    Wannier, T.3    Bloch, J.4    Mir, A.5    Schwab, M.E.6    Rouiller, E.M.7
  • 33
    • 33745879440 scopus 로고    scopus 로고
    • Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates
    • DOI 10.1038/nm1436, PII NM1436
    • Freund, P., Schmidlin, E., Wannier, T., Bloch, J., Mir, A., Schwab, M.E., and Rouiller, E.M. (2006). Nogo-A-specific antibody treatment enhances sprouting and functional recovery after cervical lesion in adult primates. Nat. Med. 12, 790-792. (Pubitemid 44050068)
    • (2006) Nature Medicine , vol.12 , Issue.7 , pp. 790-792
    • Freund, P.1    Schmidlin, E.2    Wannier, T.3    Bloch, J.4    Mir, A.5    Schwab, M.E.6    Rouiller, E.M.7
  • 34
    • 34248353098 scopus 로고    scopus 로고
    • Anti-Nogo-A antibody treatment enhances sprouting of corticospinal axons rostral to a unilateral cervical spinal cord lesion in adult macaque monkey
    • DOI 10.1002/cne.21321
    • Freund, P., Wannier, T., Schmidlin, E., Bloch, J., Mir, A., Schwab, M.E., and Rouiller, E.M. (2007). Anti-Nogo-A antibody treatment enhances sprouting of corticospinal axons rostral to a unilateral cervical spinal cord lesion in adult macaque monkey. J. Comp. Neurol. 502, 644-659. (Pubitemid 46732514)
    • (2007) Journal of Comparative Neurology , vol.502 , Issue.4 , pp. 644-659
    • Freund, P.1    Wannier, T.2    Schmidlin, E.3    Bloch, J.4    Mir, A.5    Schwab, M.E.6    Rouiller, E.M.7
  • 35
    • 0037198689 scopus 로고    scopus 로고
    • Nogo-66 receptor antagonist peptide promotes axonal regeneration
    • DOI 10.1038/417547a
    • GrandPre, T., Li, S., and Strittmatter, S.M. (2002). Nogo-66 receptor antagonist peptide promotes axonal regeneration. Nature 417, 547-551. (Pubitemid 34595921)
    • (2002) Nature , vol.417 , Issue.6888 , pp. 547-551
    • GrandPre, T.1    Shuxin, L.I.2    Strittmatter, S.M.3
  • 37
    • 20844439022 scopus 로고    scopus 로고
    • Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury
    • DOI 10.1523/JNEUROSCI.2828-04.2004
    • Li, S., Liu, B.P., Budel, S., Li, M., Ji, B., Walus, L., Li, W., Jirik, A., Rabacchi, S., Choi, E., Worley, D., Sah, D.W., Pepinsky, B., Lee, D., Relton, J., and Strittmatter, S.M. (2004). Blockade of Nogo-66, myelin-associated glycoprotein, and oligodendrocyte myelin glycoprotein by soluble Nogo-66 receptor promotes axonal sprouting and recovery after spinal injury. J. Neurosci. 24, 10511-10520. (Pubitemid 39552636)
    • (2004) Journal of Neuroscience , vol.24 , Issue.46 , pp. 10511-10520
    • Li, S.1    Liu, B.P.2    Budel, S.3    Li, M.4    Ji, B.5    Walus, L.6    Li, W.7    Jirik, A.8    Rabacchi, S.9    Choi, E.10    Worley, D.11    Sah, D.W.Y.12    Pepinsky, B.13    Lee, D.14    Relton, J.15    Strittmatter, S.M.16
  • 38
    • 0038042274 scopus 로고    scopus 로고
    • Delayed systemic Nogo-66 receptor antagonist promotes recovery from spinal cord injury
    • Li, S., and Strittmatter, S.M. (2003). Delayed systematic Nogo-66 receptor antagonist promotes recovery from spinal cord injury. J. Neurosci. 23, 4219-4227. (Pubitemid 36958442)
    • (2003) Journal of Neuroscience , vol.23 , Issue.10 , pp. 4219-4227
    • Li, S.1    Strittmatter, S.M.2
  • 40
    • 67649388365 scopus 로고    scopus 로고
    • Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury
    • Maier, I.C., Ichiyama, R.M., Courtine, G., Schnell, L., Lavrov, I., Edgerton, V.R., and Schwab, M.E. (2009). Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury. Brain 132, 1426-1440.
    • (2009) Brain , vol.132 , pp. 1426-1440
    • Maier, I.C.1    Ichiyama, R.M.2    Courtine, G.3    Schnell, L.4    Lavrov, I.5    Edgerton, V.R.6    Schwab, M.E.7
  • 41
    • 0035873174 scopus 로고    scopus 로고
    • Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A
    • Merkler, D.,Metz, G.A., Rainteau, O., Dietz, V., Schwab,M.E., and Fouad, K. (2001). Locomotor recovery in spinal cord-injured rats treated with an antibody neutralizing the myelin-associated neurite growth inhibitor Nogo-A. J. Neurosci. 21, 3665-3673. (Pubitemid 32422831)
    • (2001) Journal of Neuroscience , vol.21 , Issue.10 , pp. 3665-3673
    • Merkler, D.1    Metz, G.A.S.2    Raineteau, O.3    Dietz, V.4    Schwab, M.E.5    Fouad, K.6
  • 42
    • 0036436365 scopus 로고    scopus 로고
    • Reorganization of descending motor tracts in the rat spinal cord
    • DOI 10.1046/j.1460-9568.2002.02243.x
    • Raineteau, O., Fouad, K., Bereyre, F.M., and Schwab, M.E. (2002). Reorganization of descending motor tracts in the rat spinal cord. Eur. J. Neurosci. 16, 1761-1771. (Pubitemid 35370709)
    • (2002) European Journal of Neuroscience , vol.16 , Issue.9 , pp. 1761-1771
    • Raineteau, O.1    Fouad, K.2    Bareyre, F.M.3    Schwab, M.E.4
  • 44
    • 0033000956 scopus 로고    scopus 로고
    • Sprouting and regeneration after pyramidotomy and blockade of the myelin-associated neurite growth inhibitors NI 35/250 in adult rats
    • DOI 10.1046/j.1460-9568.1999.00560.x
    • Raineteau, O., Z'Graggen, W.J., Thallmair, M., and Schwab, M.E. (1999). Sprouting and regeneration after pyramidotomy and blockade of the myelin-associated neurite growth inhibitors NI 35/250 in adult rats. Eur. J. Neurosci. 11, 1486-1490. (Pubitemid 29142207)
    • (1999) European Journal of Neuroscience , vol.11 , Issue.4 , pp. 1486-1490
    • Raineteau, O.1
  • 45
    • 0025017637 scopus 로고
    • Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
    • DOI 10.1038/343269a0
    • Schnell, L., and Schwab, M.E. (1990). Axonal regneration in the rat spinal cord produced by an antibody against myelinassociated neurite growth inhibitors. Nature 343, 269-272. (Pubitemid 20030644)
    • (1990) Nature , vol.343 , Issue.6255 , pp. 269-272
    • Schnell, L.1    Schwab, M.E.2
  • 46
    • 38649105790 scopus 로고    scopus 로고
    • A re-assessment of the effects of a Nogo-66 receptor on regenerative growth of axons and locomotor recovery after spinal cord injury in mice
    • Steward, O., Sharp, K., Yee, K.M., and Hofstadter, M. (2008). A re-assessment of the effects of a Nogo-66 receptor on regenerative growth of axons and locomotor recovery after spinal cord injury in mice. Exp. Neurol. 209, 446-468.
    • (2008) Exp. Neurol. , vol.209 , pp. 446-468
    • Steward, O.1    Sharp, K.2    Yee, K.M.3    Hofstadter, M.4
  • 47
    • 0032082502 scopus 로고    scopus 로고
    • Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions
    • Thallmair, M., Metz, G.A., Z'Graggen, W.J., Raineteau, O., Kartje, G.L., and Schwab, M.E. (1998). Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions. Nat. Neurosci. 1, 124-131.
    • (1998) Nat. Neurosci. , vol.1 , pp. 124-131
    • Thallmair, M.1    Metz, G.A.2    Z'graggen, W.J.3    Raineteau, O.4    Kartje, G.L.5    Schwab, M.E.6
  • 48
    • 0032428520 scopus 로고    scopus 로고
    • Regeneration and sprouting of chronically injured corticospinal tract fibers in adult rats promoted by NT-3 and the mAb IN-1, which neutralizes myelin-associated neurite growth inhibitors
    • Von Meyenburg, J., Brosamle, C., Metz, G.A., and Schwab, M.E. (1998). Regeneration and sprouting of chronically injured corticospinal tract fibers in adult rats promoted by NT-3 and the mAb IN-1, which neutralizes myelin-associated neurite growth inhibitors. Exp. Neurol. 154, 583-594.
    • (1998) Exp. Neurol. , vol.154 , pp. 583-594
    • Von Meyenburg, J.1    Brosamle, C.2    Metz, G.A.3    Schwab, M.E.4
  • 49
    • 33845285911 scopus 로고    scopus 로고
    • Delayed nogo receptor therapy improves recovery from spinal cord contusion
    • DOI 10.1002/ana.20953
    • Wang, X., Baughman, K.W., Basso, D.M., and Strittmatter, S.M. (2006). Delayed Nogo receptor therapy improves recovery from spinal cord contusion. Ann. Neurol. 60, 540-549. (Pubitemid 44871796)
    • (2006) Annals of Neurology , vol.60 , Issue.5 , pp. 540-549
    • Wang, X.1    Baughman, K.W.2    Basso, D.M.3    Strittmatter, S.M.4
  • 50
    • 39149142805 scopus 로고    scopus 로고
    • Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: Effects of an antibody treatment neutralizing Nogo-A
    • Wannier-Morino, P., Schmidlin, E., Freund, P., Belhaj-Saif, A., Bloch, J., Mir, A., Schwab, M.E., Rouiller, E.M., and Wannier, T. (2008). Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: effects of an antibody treatment neutralizing Nogo-A. Brain Res. 1217, 96-109.
    • (2008) Brain Res. , vol.1217 , pp. 96-109
    • Wannier-Morino, P.1    Schmidlin, E.2    Freund, P.3    Belhaj-Saif, A.4    Bloch, J.5    Mir, A.6    Schwab, M.E.7    Rouiller, E.M.8    Wannier, T.9
  • 51
    • 0032526742 scopus 로고    scopus 로고
    • Functional recovery and enhanced corticofugal plasticity after unilateral pyramidal tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats
    • Z'Graggen, W.J., Metz, G.A., Kartje, G.L., Thallmair, M., and Schwab, M.E. (1998). Functional recovery and enhanced corticofugal plasticity after unilateral pyramid tract lesion and blockade of myelin-associated neurite growth inhibitors in adult rats. J. Neurosci. 18, 4744-4757. (Pubitemid 28280182)
    • (1998) Journal of Neuroscience , vol.18 , Issue.12 , pp. 4744-4757
    • Z'Graggen, W.J.1    Metz, G.A.S.2    Kartje, G.L.3    Thallmair, M.4    Schwab, M.E.5
  • 52
    • 27744532683 scopus 로고    scopus 로고
    • Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury
    • DOI 10.1016/j.expneurol.2005.08.011, PII S0014488605002967
    • Chan, C.C., Khodarahmi, K., Liu, J., Sutherland, D., Oschipok, L.W., Steeves, J.D., and Tetzlaff, W. (2005). Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury. Exp. Neurol. 196, 352-364. (Pubitemid 41607824)
    • (2005) Experimental Neurology , vol.196 , Issue.2 , pp. 352-364
    • Chan, C.C.M.1    Khodarahmi, K.2    Liu, J.3    Sutherland, D.4    Oschipok, L.W.5    Steeves, J.D.6    Tetzlaff, W.7
  • 54
    • 0042171820 scopus 로고    scopus 로고
    • Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
    • DOI 10.1083/jcb.200301080
    • Dubreuil, C.I., Winton, M.J., and McKerracher, L. (2003). Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J. Cell. Biol. 162, 233-243. (Pubitemid 36928837)
    • (2003) Journal of Cell Biology , vol.162 , Issue.2 , pp. 233-243
    • Dubreuil, C.I.1    Winton, M.J.2    McKerracher, L.3
  • 55
    • 0037443069 scopus 로고    scopus 로고
    • Rho kinase inhibition enhances axonal regeneration in the injured CNS
    • Fournier, A.E., Takizawa, B.T., and Strittmatter, S.M. (2003). Rho kinase inhibition enhances axonal regeneration in the injured CNS. J. Neurosci. 23, 1416-1423. (Pubitemid 36258920)
    • (2003) Journal of Neuroscience , vol.23 , Issue.4 , pp. 1416-1423
    • Fournier, A.E.1    Takizawa, B.T.2    Strittmatter, S.M.3
  • 56
    • 57349179914 scopus 로고    scopus 로고
    • Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury
    • Lord-Fontaine, S., Yang, F., Diep, Q., Dergham, P., Munzer, S., Tremblay, P., and McKerracher, L. (2008). Local inhibition of Rho signaling by cell-permeable recombinant protein BA-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury. J. Neurotrauma 25, 1309-1322.
    • (2008) J. Neurotraum , vol.25 , pp. 1309-1322
    • Lord-Fontaine, S.1    Yang, F.2    Diep, Q.3    Dergham, P.4    Munzer, S.5    Tremblay, P.6    McKerracher, L.7
  • 57
    • 33746286637 scopus 로고    scopus 로고
    • Delayed treatment with Rho-kinase inhibitor does not enhance axonal regeneration or functional recovery after spinal cord injury in rats
    • DOI 10.1016/j.expneurol.2006.02.123, PII S0014488606001828
    • Nishio, Y., Koda, M., Kitajo, K., Seto, M., Hata, K., Taniguchi, J., Moriya, H., Fujitani, M., Kubo, T., and Yamashita, T. (2006). Delayed treatment with Rho-kinase inhibitor does not enhance axonal regeneration or functional recovery after spinal cord injury in rats. Exp. Neurol. 200, 392-397. (Pubitemid 44107920)
    • (2006) Experimental Neurology , vol.200 , Issue.2 , pp. 392-397
    • Nishio, Y.1    Koda, M.2    Kitajo, K.3    Seto, M.4    Hata, K.5    Taniguchi, J.6    Moriya, H.7    Fujitani, M.8    Kubo, T.9    Yamashita, T.10
  • 58
    • 0037414673 scopus 로고    scopus 로고
    • A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat
    • DOI 10.1016/S0006-8993(02)03717-4, PII S0006899302037174
    • Sung, J.K., Miao, L., Calvert, J.W., Huang, L., Louis, H.H., and Zhang, J.H. (2003). A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat. Brain Res. 959, 29-38. (Pubitemid 35435403)
    • (2003) Brain Research , vol.959 , Issue.1 , pp. 29-38
    • Sung, J.-K.1    Miao, L.2    Calvert, J.W.3    Huang, L.4    Harkey, H.L.5    Zhang, J.H.6
  • 59
    • 3042552705 scopus 로고    scopus 로고
    • Cip1/WAF1 enhances axonal regeneration and functional recovery after spinal cord injury in rats
    • DOI 10.1016/j.neuroscience.2004.05.010, PII S0306452204003653
    • Tanaka, H., Yamashita, T., Yachi, K., Fujiwara, T., Yoshikawa, H., and Tohyama, M. (2004). Cytoplasmic p21(Cip1/WAF1) enhances axonal regeneration and functional recovery after spinal cord injury in rats. Neuroscience 127, 155-164. (Pubitemid 38829161)
    • (2004) Neuroscience , vol.127 , Issue.1 , pp. 155-164
    • Tanaka, H.1    Yamashita, T.2    Yachi, K.3    Fujiwara, T.4    Yoshikawa, H.5    Tohyama, M.6


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