-
1
-
-
19444382327
-
The dynamics of autophagy visualized in live cells: From autophagosome formation to fusion with endo/lysosomes
-
Bampton ET, Goemans CG, Niranjan D, Mizushima N, Tolkovsky AM (2005) The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes. Autophagy 1:23-36
-
(2005)
Autophagy
, vol.1
, pp. 23-36
-
-
Bampton, E.T.1
Goemans, C.G.2
Niranjan, D.3
Mizushima, N.4
Tolkovsky, A.M.5
-
2
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HT (2008) A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456:259-263
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
Kishi, C.7
Kc, W.8
Carrero, J.A.9
Hunt, S.10
Stone, C.D.11
Brunt, E.M.12
Xavier, R.J.13
Sleckman, B.P.14
Li, E.15
Mizushima, N.16
Stappenbeck, T.S.17
Virgin, H.T.18
-
3
-
-
79958799724
-
ATG16L1 contribution to Crohn's disease risk in Sicily
-
Fabio RR, Concetta RM, Giuseppe C, Sara R, Ambrogio O, Aurelio M, Mario C (2011) ATG16L1 contribution to Crohn's disease risk in Sicily. Inflamm Bowel Dis 17:1635-1636
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1635-1636
-
-
Fabio, R.R.1
Concetta, R.M.2
Giuseppe, C.3
Sara, R.4
Ambrogio, O.5
Aurelio, M.6
Mario, C.7
-
4
-
-
80052641505
-
Crohn's disease: NOD2, autophagy and ER stress converge
-
Fritz T, Niederreiter L, Adolph T, Blumberg RS, Kaser A (2011) Crohn's disease: NOD2, autophagy and ER stress converge. Gut 60:1580-1588
-
(2011)
Gut
, vol.60
, pp. 1580-1588
-
-
Fritz, T.1
Niederreiter, L.2
Adolph, T.3
Blumberg, R.S.4
Kaser, A.5
-
5
-
-
74049140368
-
Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy
-
Fujioka Y, Noda NN, Nakatogawa H, Ohsumi Y, Inagaki F (2010) Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy. J Biol Chem 285:1508-1515
-
(2010)
J Biol Chem
, vol.285
, pp. 1508-1515
-
-
Fujioka, Y.1
Noda, N.N.2
Nakatogawa, H.3
Ohsumi, Y.4
Inagaki, F.5
-
6
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T (2008) The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 19:2092-2100
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
7
-
-
70450248450
-
Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: Analysis of the organization of the Atg16L1 complex in fibroblasts
-
Fujita N, Saitoh T, Kageyama S, Akira S, Noda T, Yoshimori T (2009) Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: analysis of the organization of the Atg16L1 complex in fibroblasts. J Biol Chem 284:32602-32609
-
(2009)
J Biol Chem
, vol.284
, pp. 32602-32609
-
-
Fujita, N.1
Saitoh, T.2
Kageyama, S.3
Akira, S.4
Noda, T.5
Yoshimori, T.6
-
8
-
-
50249131810
-
Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals
-
Fukuda M, Itoh T (2008) Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals. Autophagy 4:824-826
-
(2008)
Autophagy
, vol.4
, pp. 824-826
-
-
Fukuda, M.1
Itoh, T.2
-
9
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Gunther S, Prescott NJ, Onnie CM, Hasler R, Sipos B, Folsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S (2007) A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 39:207-211
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
10
-
-
84863344601
-
Phospho-DeltaNp63alpha-dependent regulation of autophagic signaling through transcription and micro-RNA modulation
-
Huang Y, Guerrero-Preston R, Ratovitski EA (2012) Phospho-DeltaNp63alpha- dependent regulation of autophagic signaling through transcription and micro-RNA modulation. Cell Cycle 11:1247-1259
-
(2012)
Cell Cycle
, vol.11
, pp. 1247-1259
-
-
Huang, Y.1
Guerrero-Preston, R.2
Ratovitski, E.A.3
-
11
-
-
84859982621
-
Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon gamma
-
Hwang S, Maloney NS, Bruinsma MW, Goel G, Duan E, Zhang L, Shrestha B, Diamond MS, Dani A, Sosnovtsev SV, Green KY, Lopez-Otin C, Xavier RJ, Thackray LB, Virgin HW (2012) Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon gamma. Cell Host Microbe 11:397-409
-
(2012)
Cell Host Microbe
, vol.11
, pp. 397-409
-
-
Hwang, S.1
Maloney, N.S.2
Bruinsma, M.W.3
Goel, G.4
Duan, E.5
Zhang, L.6
Shrestha, B.7
Diamond, M.S.8
Dani, A.9
Sosnovtsev, S.V.10
Green, K.Y.11
Lopez-Otin, C.12
Xavier, R.J.13
Thackray, L.B.14
Virgin, H.W.15
-
12
-
-
50249098491
-
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation
-
Itoh T, Fujita N, Kanno E, Yamamoto A, Yoshimori T, Fukuda M (2008) Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell 19:2916-2925
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2916-2925
-
-
Itoh, T.1
Fujita, N.2
Kanno, E.3
Yamamoto, A.4
Yoshimori, T.5
Fukuda, M.6
-
13
-
-
84871888497
-
Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity
-
Koutaro I, Takefumi U, Satoshi W, Mitsunori F (2012) Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity. Mol Biol Cell 23:3193-3202
-
(2012)
Mol Biol Cell
, vol.23
, pp. 3193-3202
-
-
Koutaro, I.1
Takefumi, U.2
Satoshi, W.3
Mitsunori, F.4
-
14
-
-
0037166241
-
Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast
-
Kuma A, Mizushima N, Ishihara N, Ohsumi Y (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277:18619-18625
-
(2002)
J Biol Chem
, vol.277
, pp. 18619-18625
-
-
Kuma, A.1
Mizushima, N.2
Ishihara, N.3
Ohsumi, Y.4
-
15
-
-
84863078686
-
Autophagy suppresses interleukin-1beta (IL-1beta) signaling by activation of p62 degradation via lysosomal and proteasomal pathways
-
Lee J, Kim HR, Quinley C, Kim J, Gonzalez-Navajas J, Xavier R, Raz E (2012) Autophagy suppresses interleukin-1beta (IL-1beta) signaling by activation of p62 degradation via lysosomal and proteasomal pathways. J Biol Chem 287:4033-4040
-
(2012)
J Biol Chem
, vol.287
, pp. 4033-4040
-
-
Lee, J.1
Kim, H.R.2
Quinley, C.3
Kim, J.4
Gonzalez-Navajas, J.5
Xavier, R.6
Raz, E.7
-
16
-
-
80655149205
-
New IBD genetics: Common pathways with other diseases
-
Lees CW, Barrett JC, Parkes M, Satsangi J (2011) New IBD genetics: common pathways with other diseases. Gut 60:1739-1753
-
(2011)
Gut
, vol.60
, pp. 1739-1753
-
-
Lees, C.W.1
Barrett, J.C.2
Parkes, M.3
Satsangi, J.4
-
17
-
-
0038325675
-
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
-
Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, Natsume T, Ohsumi Y, Yoshimori T (2003) Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci 116:1679-1688
-
(2003)
J Cell Sci
, vol.116
, pp. 1679-1688
-
-
Mizushima, N.1
Kuma, A.2
Kobayashi, Y.3
Yamamoto, A.4
Matsubae, M.5
Takao, T.6
Natsume, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
18
-
-
79960774898
-
Autophagosome precursor maturation requires homotypic fusion
-
Moreau K, Ravikumar B, Renna M, Puri C, Rubinsztein DC (2011) Autophagosome precursor maturation requires homotypic fusion. Cell 146:303-317
-
(2011)
Cell
, vol.146
, pp. 303-317
-
-
Moreau, K.1
Ravikumar, B.2
Renna, M.3
Puri, C.4
Rubinsztein, D.C.5
-
19
-
-
0034757896
-
A novel assay to study autophagy: Regulation of autophagosome vacuole size by amino acid deprivation
-
Munafo DB, Colombo MI (2001) A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation. J Cell Sci 114:3619-3629
-
(2001)
J Cell Sci
, vol.114
, pp. 3619-3629
-
-
Munafo, D.B.1
Colombo, M.I.2
-
20
-
-
80051550866
-
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2
-
Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong D.J., Philpott D.J., van der Meer JW, Girardin SE, Joosten LA, Netea M.G. (2011) Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut 60:1229-1235
-
(2011)
Gut
, vol.60
, pp. 1229-1235
-
-
Plantinga, T.S.1
Crisan, T.O.2
Oosting, M.3
Van De Veerdonk, F.L.4
De Jong, D.J.5
Philpott, D.J.6
Van Der Meer, J.W.7
Girardin, S.E.8
Joosten, L.A.9
Netea, M.G.10
-
21
-
-
84860223287
-
Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans
-
Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, Hold G, Kunstmann E, Yoshimori T, Silverberg MS, Girardin SE, Philpott D.J., El OE, Jones NL (2012) Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology 142:1160-1171
-
(2012)
Gastroenterology
, vol.142
, pp. 1160-1171
-
-
Raju, D.1
Hussey, S.2
Ang, M.3
Terebiznik, M.R.4
Sibony, M.5
Galindo-Mata, E.6
Gupta, V.7
Blanke, S.R.8
Delgado, A.9
Romero-Gallo, J.10
Ramjeet, M.S.11
Mascarenhas, H.12
Peek, R.M.13
Correa, P.14
Streutker, C.15
Hold, G.16
Kunstmann, E.17
Yoshimori, T.18
Silverberg, M.S.19
Girardin, S.E.20
Philpott, D.J.21
El, O.E.22
Jones, N.L.23
more..
-
22
-
-
77955131007
-
Plasma membrane contributes to the formation of preautophagosomal structures
-
Ravikumar B, Moreau K, Jahreiss L, Puri C, Rubinsztein DC (2010) Plasma membrane contributes to the formation of preautophagosomal structures. Nat Cell Biol 12:747-757
-
(2010)
Nat Cell Biol
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.C.5
-
23
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR (2007) Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 39:596-604
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
24
-
-
84866346322
-
Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-αlpha
-
Saito M, Katsuno T, Nakagawa T, Sato T, Noguchi Y, Sazuka S, Saito K, Arai M, Yokote K, Yokosuka O (2012) Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-αlpha. Dig Dis Sci 8:2022-2030
-
(2012)
Dig Dis Sci
, vol.8
, pp. 2022-2030
-
-
Saito, M.1
Katsuno, T.2
Nakagawa, T.3
Sato, T.4
Noguchi, Y.5
Sazuka, S.6
Saito, K.7
Arai, M.8
Yokote, K.9
Yokosuka, O.10
-
25
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S (2008) Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 456:264-268
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
26
-
-
42649090428
-
Autophagy and endocytosis in the amnion
-
Shen ZY, Xu LY, Li EM, Zhuang BR, Lu XF, Shen J, Wu XY, Li QS, Lin YJ, Chen YW, Tan LJ (2008) Autophagy and endocytosis in the amnion. J Struct Biol 162:197-204
-
(2008)
J Struct Biol
, vol.162
, pp. 197-204
-
-
Shen, Z.Y.1
Xu, L.Y.2
Li, E.M.3
Zhuang, B.R.4
Lu, X.F.5
Shen, J.6
Wu, X.Y.7
Li, Q.S.8
Lin, Y.J.9
Chen, Y.W.10
Tan, L.J.11
-
28
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhaes JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nunez G, Girardin SE, Philpott D.J. (2010) Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11:55-62
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
Magalhaes, J.G.6
Yuan, L.7
Soares, F.8
Chea, E.9
Le Bourhis, L.10
Boneca, I.G.11
Allaoui, A.12
Jones, N.L.13
Nunez, G.14
Girardin, S.E.15
Philpott, D.J.16
-
29
-
-
84856007744
-
Role of genetics in the diagnosis and prognosis of Crohn's disease
-
Tsianos EV, Katsanos KH, Tsianos VE (2012) Role of genetics in the diagnosis and prognosis of Crohn's disease. World J Gastroenterol 18:105-118
-
(2012)
World J Gastroenterol
, vol.18
, pp. 105-118
-
-
Tsianos, E.V.1
Katsanos, K.H.2
Tsianos, V.E.3
-
30
-
-
73449121083
-
Using LC3 to monitor autophagy flux in the retinal pigment epithelium
-
Wang AL, Boulton ME, Dunn WJ, Rao HV, Cai J, Lukas TJ, Neufeld AH (2009) Using LC3 to monitor autophagy flux in the retinal pigment epithelium. Autophagy 5:1190-1193
-
(2009)
Autophagy
, vol.5
, pp. 1190-1193
-
-
Wang, A.L.1
Boulton, M.E.2
Dunn, W.J.3
Rao, H.V.4
Cai, J.5
Lukas, T.J.6
Neufeld, A.H.7
-
31
-
-
84861615385
-
Autophagy attenuates the adaptive immune response by destabilizing the immunologic synapse
-
Wildenberg ME, Vos AC, Wolfkamp SC, Duijvestein M, Verhaar AP, Te VA, van den Brink GR, Hommes DW (2012) Autophagy attenuates the adaptive immune response by destabilizing the immunologic synapse. Gastroenterology 142:1493-1503
-
(2012)
Gastroenterology
, vol.142
, pp. 1493-1503
-
-
Wildenberg, M.E.1
Vos, A.C.2
Wolfkamp, S.C.3
Duijvestein, M.4
Verhaar, A.P.5
Te, V.A.6
Van Den Brink, G.R.7
Hommes, D.W.8
-
32
-
-
28144431882
-
Molecular cloning and characterization of rat LC3A and LC3B: Two novel markers of autophagosome
-
Wu J, Dang Y, Su W, Liu C, Ma H, Shan Y, Pei Y, Wan B, Guo J, Yu L (2006) Molecular cloning and characterization of rat LC3A and LC3B: two novel markers of autophagosome. Biochem Biophys Res Commun 339:437-442
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 437-442
-
-
Wu, J.1
Dang, Y.2
Su, W.3
Liu, C.4
Ma, H.5
Shan, Y.6
Pei, Y.7
Wan, B.8
Guo, J.9
Yu, L.10
-
33
-
-
7444244288
-
Cloning and analysis of human Apg16L
-
Zheng H, Ji C, Li J, Jiang H, Ren M, Lu Q, Gu S, Mao Y, Xie Y (2004) Cloning and analysis of human Apg16L. DNA Seq 15:303-305
-
(2004)
DNA Seq
, vol.15
, pp. 303-305
-
-
Zheng, H.1
Ji, C.2
Li, J.3
Jiang, H.4
Ren, M.5
Lu, Q.6
Gu, S.7
Mao, Y.8
Xie, Y.9
|