-
1
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science. 2010;330:1344-1348.
-
(2010)
Science.
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
2
-
-
36249025723
-
Autophagy: Process and function
-
Mizushima N. Autophagy: process and function. Genes Dev. 2007;21:2861-2873.
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
3
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet. 2009;43:67-93.
-
(2009)
Annu Rev Genet.
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
4
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature. 2011;469:323-335.
-
(2011)
Nature.
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
5
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature. 2006;441:885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
-
6
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature. 2006;441:880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
-
7
-
-
34248994604
-
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models
-
Sarkar S, Perlstein EO, Imarisio S, et al. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. Nat Chem Biol. 2007;3:331-338.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 331-338
-
-
Sarkar, S.1
Perlstein, E.O.2
Imarisio, S.3
-
8
-
-
33947416152
-
Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection
-
Py BF, Lipinski MM, Yuan J. Autophagy limits Listeria monocytogenes intracellular growth in the early phase of primary infection. Autophagy. 2007;3:117-125.
-
(2007)
Autophagy
, vol.3
, pp. 117-125
-
-
Py, B.F.1
Lipinski, M.M.2
Yuan, J.3
-
9
-
-
33744958258
-
Autophagy controls Salmonella infection in response to damage to the Salmonella- containing vacuole
-
Birmingham CL, Smith AC, Bakowski MA, et al. Autophagy controls Salmonella infection in response to damage to the Salmonella- containing vacuole. J Biol Chem. 2006;281:11374-11383.
-
(2006)
J Biol Chem
, vol.281
, pp. 11374-11383
-
-
Birmingham, C.L.1
Smith, A.C.2
Bakowski, M.A.3
-
10
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007; 39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
11
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Consortium. TWTCC.
-
Consortium. TWTCC. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447:661-678.
-
(2007)
Nature.
, vol.447
, pp. 661-678
-
-
-
12
-
-
37249006192
-
New links to the pathogenesis of Crohn disease provided by genome-wide association scans
-
Mathew CG. New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet. 2008;9:9-14.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 9-14
-
-
Mathew, C.G.1
-
13
-
-
44149123849
-
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis
-
Xavier RJ, Huett A, Rioux JD. Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesis. Gut. 2008;57:717-720.
-
(2008)
Gut
, vol.57
, pp. 717-720
-
-
Xavier, R.J.1
Huett, A.2
Rioux, J.D.3
-
14
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol. 2010;11:55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
15
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16:90-97.
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
16
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, et al. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS ONE. 2008;3:e3391.
-
(2008)
PLoS ONE.
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
-
17
-
-
0005677775
-
3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
-
Seglen PO, Gordon PB. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci USA. 1982;79:1889-1892.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 1889-1892
-
-
Seglen, P.O.1
Gordon, P.B.2
-
18
-
-
0025694803
-
Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine
-
Hendil KB, Lauridsen AM, Seglen PO. Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine. Biochem J. 1990;272:577-581.
-
(1990)
Biochem J.
, vol.272
, pp. 577-581
-
-
Hendil, K.B.1
Lauridsen, A.M.2
Seglen, P.O.3
-
19
-
-
0027164524
-
Rapid induction and isolation of focal adhesion complexes
-
Plopper G, Ingber DE. Rapid induction and isolation of focal adhesion complexes. Biochem Biophys Res Commun. 1993;193: 571-578.
-
(1993)
Biochem Biophys Res Commun.
, vol.193
, pp. 571-578
-
-
Plopper, G.1
Ingber, D.E.2
-
20
-
-
0032782860
-
TNFalpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase
-
Koukouritaki SB, Vardaki EA, Papakonstanti EA, et al. TNFalpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinase. Mol Med. 1999;5:382-392.
-
(1999)
Mol Med
, vol.5
, pp. 382-392
-
-
Koukouritaki, S.B.1
Vardaki, E.A.2
Papakonstanti, E.A.3
-
21
-
-
66049141980
-
Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation
-
Campos SB, Ashworth SL, Wean S, et al. Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation. Am J Physiol Renal Physiol. 2009;296:F487-F495.
-
(2009)
Am J Physiol Renal Physiol.
, vol.296
-
-
Campos, S.B.1
Ashworth, S.L.2
Wean, S.3
-
22
-
-
77953796877
-
Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment
-
Kadandale P, Stender JD, Glass CK, et al. Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitment. Proc Natl Acad Sci USA. 2010;107:10502-10507.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 10502-10507
-
-
Kadandale, P.1
Stender, J.D.2
Glass, C.K.3
-
23
-
-
0642283970
-
Regulation of proliferation, survival and apoptosis by members of the TNF superfamily
-
Gaur U, Aggarwal BB. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol. 2003;66:1403-1408.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1403-1408
-
-
Gaur, U.1
Aggarwal, B.B.2
-
24
-
-
0032704934
-
The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
-
Kollias G, Douni E, Kassiotis G, et al. The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease. Ann Rheum Dis. 1999;58:I32-I39.
-
(1999)
Ann Rheum Dis.
, vol.58
-
-
Kollias, G.1
Douni, E.2
Kassiotis, G.3
-
25
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science. 2002;296:1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
26
-
-
79952498248
-
TNFR1-induced activation of the classical NF-kappaB pathway
-
Wajant H, Scheurich P. TNFR1-induced activation of the classical NF-kappaB pathway. FEBS J. 2011;278:862-876.
-
(2011)
FEBS J
, vol.278
, pp. 862-876
-
-
Wajant, H.1
Scheurich, P.2
-
28
-
-
79151474603
-
Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-kappaB activation
-
Fujishima Y, Nishiumi S, Masuda A, et al. Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-kappaB activation. Arch Biochem Biophys. 2011;506:223-235.
-
(2011)
Arch Biochem Biophys
, vol.506
, pp. 223-235
-
-
Fujishima, Y.1
Nishiumi, S.2
Masuda, A.3
-
31
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell. 2002;110:673-687.
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
33
-
-
0030479197
-
Integrins: Role in cell adhesion and communication
-
Gille J, Swerlick RA. Integrins: role in cell adhesion and communication. Ann N Y Acad Sci. 1996;797:93-106.
-
(1996)
Ann N y Acad Sci.
, vol.797
, pp. 93-106
-
-
Gille, J.1
Swerlick, R.A.2
-
34
-
-
0032493934
-
Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes
-
Hodivala-Dilke KM, DiPersio CM, Kreidberg JA, et al. Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes. J Cell Biol. 1998;142:1357-1369.
-
(1998)
J Cell Biol
, vol.142
, pp. 1357-1369
-
-
Hodivala-Dilke, K.M.1
Dipersio, C.M.2
Kreidberg, J.A.3
-
35
-
-
4444361792
-
Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1
-
Choma DP, Pumiglia K, DiPersio CM. Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1. J Cell Sci. 2004;117:3947-3959.
-
(2004)
J Cell Sci
, vol.117
, pp. 3947-3959
-
-
Choma, D.P.1
Pumiglia, K.2
Dipersio, C.M.3
-
36
-
-
0034668127
-
Adhesion complexes implicated in intestinal epithelial cell-matrix interactions
-
Stutzmann J, Bellissent-Waydelich A, Fontao L, et al. Adhesion complexes implicated in intestinal epithelial cell-matrix interactions. Microsc Res Tech. 2000;51:179-190.
-
(2000)
Microsc Res Tech
, vol.51
, pp. 179-190
-
-
Stutzmann, J.1
Bellissent-Waydelich, A.2
Fontao, L.3
-
37
-
-
67349153324
-
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment
-
Kim M, Ogawa M, Fujita Y, et al. Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment. Nature. 2009;459:578-582.
-
(2009)
Nature
, vol.459
, pp. 578-582
-
-
Kim, M.1
Ogawa, M.2
Fujita, Y.3
-
38
-
-
77956296581
-
Humanrestricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation
-
Muenzner P, Bachmann V, Zimmermann W, et al. Humanrestricted bacterial pathogens block shedding of epithelial cells by stimulating integrin activation. Science. 2010;329:1197-1201.
-
(2010)
Science
, vol.329
, pp. 1197-1201
-
-
Muenzner, P.1
Bachmann, V.2
Zimmermann, W.3
-
39
-
-
0027452326
-
Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells
-
Kapron-Bras C, Fitz-Gibbon L, Jeevaratnam P, et al. Stimulation of tyrosine phosphorylation and accumulation of GTP-bound p21ras upon antibody-mediated alpha 2 beta 1 integrin activation in T-lymphoblastic cells. J Biol Chem. 1993;268:20701-20704.
-
(1993)
J Biol Chem
, vol.268
, pp. 20701-20704
-
-
Kapron-Bras, C.1
Fitz-Gibbon, L.2
Jeevaratnam, P.3
-
40
-
-
0025336326
-
The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin
-
Shaw LM, Messier JM, Mercurio AM. The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrin. J Cell Biol. 1990;110:2167-2174.
-
(1990)
J Cell Biol
, vol.110
, pp. 2167-2174
-
-
Shaw, L.M.1
Messier, J.M.2
Mercurio, A.M.3
-
41
-
-
0030006484
-
TNF-alpha inactivation of collagen receptors: Implications for fibroblast function and fibrosis
-
Chou DH, Lee W, McCulloch CA. TNF-alpha inactivation of collagen receptors: implications for fibroblast function and fibrosis. J Immunol. 1996;156:4354-4362.
-
(1996)
J Immunol
, vol.156
, pp. 4354-4362
-
-
Chou, D.H.1
Lee, W.2
McCulloch, C.A.3
-
44
-
-
77950988234
-
Infliximab, azathioprine, or combination therapy for Crohn's disease
-
Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med. 2010;362:1383-1395.
-
(2010)
N Engl J Med.
, vol.362
, pp. 1383-1395
-
-
Colombel, J.F.1
Sandborn, W.J.2
Reinisch, W.3
|